DK1119634T3 - Enzymkatalyseret racematspaltning af primære aminer - Google Patents

Enzymkatalyseret racematspaltning af primære aminer

Info

Publication number
DK1119634T3
DK1119634T3 DK99941616T DK99941616T DK1119634T3 DK 1119634 T3 DK1119634 T3 DK 1119634T3 DK 99941616 T DK99941616 T DK 99941616T DK 99941616 T DK99941616 T DK 99941616T DK 1119634 T3 DK1119634 T3 DK 1119634T3
Authority
DK
Denmark
Prior art keywords
optically active
primary amines
enzyme
amine
racemate cleavage
Prior art date
Application number
DK99941616T
Other languages
Danish (da)
English (en)
Inventor
Christoph Nuebling
Klaus Ditrich
Christian Dully
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK1119634T3 publication Critical patent/DK1119634T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK99941616T 1998-08-20 1999-08-13 Enzymkatalyseret racematspaltning af primære aminer DK1119634T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19837745A DE19837745A1 (de) 1998-08-20 1998-08-20 Enzymkatalysierte Racematspaltung von primären Aminen

Publications (1)

Publication Number Publication Date
DK1119634T3 true DK1119634T3 (da) 2004-06-28

Family

ID=7878111

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99941616T DK1119634T3 (da) 1998-08-20 1999-08-13 Enzymkatalyseret racematspaltning af primære aminer

Country Status (12)

Country Link
US (1) US6465223B1 (fr)
EP (1) EP1119634B1 (fr)
JP (1) JP4493851B2 (fr)
CN (1) CN1161477C (fr)
AT (1) ATE267874T1 (fr)
AU (1) AU5516499A (fr)
BR (1) BR9913101A (fr)
CA (1) CA2341345C (fr)
DE (2) DE19837745A1 (fr)
DK (1) DK1119634T3 (fr)
ES (1) ES2221423T3 (fr)
WO (1) WO2000011203A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19956786A1 (de) * 1999-11-25 2001-05-31 Basf Ag Verfahren zur Herstellung optisch aktiver Amine
EP1315827A1 (fr) * 2000-09-08 2003-06-04 Dsm N.V. Procede permettant la preparation d'amines enrichies en enantiomeres
US7951566B2 (en) * 2005-12-13 2011-05-31 E.I. Du Pont De Nemours And Company Production of peracids using an enzyme having perhydrolysis activity
DE102006032061B4 (de) * 2006-07-11 2009-01-02 Mark, Christoph, Dr. Verfahren zur Herstellung von optisch aktiven Aminen
DE502007006556D1 (de) * 2006-09-13 2011-04-07 Basf Se Verfahren zur herstellung von optisch aktivem 2-benzyloxycyclohexylamin
WO2023160805A1 (fr) * 2022-02-25 2023-08-31 Symrise Ag Parfums à structure méthoxy-acétate
CN114561440B (zh) * 2022-04-27 2022-07-29 天津全和诚科技有限责任公司 一种高纯(r)-(+)-1-(4-甲氧基苯)乙胺单体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4332738A1 (de) * 1993-09-25 1995-03-30 Basf Ag Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung
JP3789938B2 (ja) * 1995-02-03 2006-06-28 ビーエーエスエフ アクチェンゲゼルシャフト 酵素触媒作用アシル化による1級及び2級のヘテロ原子置換アミンのラセミ体分割
DE19637336A1 (de) * 1995-12-06 1997-06-12 Bayer Ag Verfahren zur Herstellung von optisch aktiven Aminen
DE19603575A1 (de) * 1996-02-01 1997-08-07 Bayer Ag Verfahren zur Herstellung von optisch aktiven Aminen
US5981267A (en) * 1996-01-24 1999-11-09 The Scripps Research Institute Enantioselection of amines using homocarbonates with hydrolase
DE19621686A1 (de) * 1996-05-30 1997-12-04 Bayer Ag Verfahren zur Herstellung von optisch aktiven Aminen
AU7359198A (en) * 1997-05-01 1998-11-27 G.D. Searle & Co. Method and apparatus for preparation of chiral beta amino acids
DE19727517A1 (de) * 1997-06-30 1999-01-07 Basf Ag Racematspaltung von Aminosäureestern durch Enzym-katalysierte Acylierung

Also Published As

Publication number Publication date
CN1161477C (zh) 2004-08-11
WO2000011203A1 (fr) 2000-03-02
CA2341345C (fr) 2010-10-26
ATE267874T1 (de) 2004-06-15
EP1119634A1 (fr) 2001-08-01
EP1119634B1 (fr) 2004-05-26
DE59909610D1 (de) 2004-07-01
US6465223B1 (en) 2002-10-15
CN1313905A (zh) 2001-09-19
CA2341345A1 (fr) 2000-03-02
DE19837745A1 (de) 2000-02-24
BR9913101A (pt) 2001-05-08
AU5516499A (en) 2000-03-14
JP2002523055A (ja) 2002-07-30
JP4493851B2 (ja) 2010-06-30
ES2221423T3 (es) 2004-12-16

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