DK1117440T3 - Farmaceutiske sammensætninger indeholdende paclitaxel - Google Patents

Farmaceutiske sammensætninger indeholdende paclitaxel

Info

Publication number
DK1117440T3
DK1117440T3 DK99945661T DK99945661T DK1117440T3 DK 1117440 T3 DK1117440 T3 DK 1117440T3 DK 99945661 T DK99945661 T DK 99945661T DK 99945661 T DK99945661 T DK 99945661T DK 1117440 T3 DK1117440 T3 DK 1117440T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical compositions
compositions containing
containing paclitaxel
paclitaxel
long term
Prior art date
Application number
DK99945661T
Other languages
Danish (da)
English (en)
Inventor
Mark K Burchett
Cynthia A Coddington
Rajagopalan Raghavan
Earl R Speicher
Cynthia A Fragale
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1117440T3 publication Critical patent/DK1117440T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
DK99945661T 1998-10-02 1999-09-14 Farmaceutiske sammensætninger indeholdende paclitaxel DK1117440T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/165,930 US5922754A (en) 1998-10-02 1998-10-02 Pharmaceutical compositions containing paclitaxel
PCT/US1999/021024 WO2000020036A1 (en) 1998-10-02 1999-09-14 Pharmaceutical compositions containing paclitaxel

Publications (1)

Publication Number Publication Date
DK1117440T3 true DK1117440T3 (da) 2003-12-01

Family

ID=22601068

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99945661T DK1117440T3 (da) 1998-10-02 1999-09-14 Farmaceutiske sammensætninger indeholdende paclitaxel

Country Status (11)

Country Link
US (1) US5922754A (de)
EP (1) EP1117440B1 (de)
JP (1) JP2002526424A (de)
AT (1) ATE246514T1 (de)
AU (1) AU759034B2 (de)
CA (1) CA2345729A1 (de)
DE (1) DE69910230T2 (de)
DK (1) DK1117440T3 (de)
ES (1) ES2205879T3 (de)
PT (1) PT1117440E (de)
WO (1) WO2000020036A1 (de)

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KR19990075621A (ko) * 1998-03-23 1999-10-15 임성주 경사 평판형 배양조
US6017948A (en) * 1998-10-30 2000-01-25 Supergen, Inc. Water-miscible pharmaceutical compositions
US6136846A (en) * 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
JP2003521545A (ja) * 2000-02-02 2003-07-15 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 改良された溶解性を有するタキサン製剤
US8618085B2 (en) * 2000-04-28 2013-12-31 Koasn Biosciences Incorporated Therapeutic formulations of desoxyepothilones
AU2001258872C1 (en) 2000-05-12 2005-05-26 Samyang Biopharmaceuticals Corporation Method for the preparation of polymeric micelle via phase separation of block copolymer
US7217770B2 (en) * 2000-05-17 2007-05-15 Samyang Corporation Stable polymeric micelle-type drug composition and method for the preparation thereof
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
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CA2466851C (en) * 2001-11-26 2012-09-11 Supergen, Inc. Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
WO2003057128A2 (en) * 2001-12-11 2003-07-17 Dor Biopharma, Inc. Lipid particles and suspensions and uses thereof
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
CA2516056C (en) * 2003-01-06 2012-05-29 Angiochem Inc. Aprotinin and analogs as carriers across the blood-brain barrier
BRPI0520032A2 (pt) * 2005-02-18 2009-04-14 Angiochem Inc moléculas para transportar um composto através da barreira hematoencefálica
US20090016959A1 (en) * 2005-02-18 2009-01-15 Richard Beliveau Delivery of antibodies to the central nervous system
JP2008543789A (ja) * 2005-06-17 2008-12-04 ホスピラ オーストラリア ピーティーワイ エルティーディー ドセタキセルの液体薬学的処方物
BRPI0613005A8 (pt) * 2005-07-15 2017-12-26 Angiochem Inc uso de polipeptídeos de aprotinina como veículos em conjugados farmacêuticos.
AR054215A1 (es) 2006-01-20 2007-06-13 Eriochem Sa Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit
BRPI0718030A2 (pt) * 2006-10-31 2013-11-12 Wyeth Corp Formulações de inibidores de enzima de fosfolipase
US9365634B2 (en) * 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
WO2009047794A2 (en) * 2007-10-01 2009-04-16 Intas Pharmaceuticals Limited Taxane derivative composition
AR063111A1 (es) 2007-10-03 2008-12-30 Eriochem Sa Una formulacion farmaceutica de taxano
US20090098168A1 (en) * 2007-10-08 2009-04-16 The Regents Of The University Of California Multiple-layer microbubble liposphere drug delivery vehicle and system
KR101053780B1 (ko) * 2008-02-29 2011-08-02 동아제약주식회사 도세탁셀을 함유하는 단일액상의 안정한 약제학적 조성물
EP2279008B1 (de) * 2008-04-18 2019-03-06 Angiochem Inc. Pharmazeutische zusammensetzungen von paclitaxel, paclitaxel-analoga oder paclitaxel-konjugaten und relevante herstellungs- und anwendungsverfahren
ES2344674B1 (es) 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
WO2010023321A1 (en) * 2008-09-01 2010-03-04 Stragen Pharma S.A. Liquid formulation containing a taxane derivative
BRPI0920209A2 (pt) 2008-10-15 2015-12-22 Angiochem Inc conjugados de agonistas de glp-1 e usos dos mesmos
WO2010043049A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Etoposide and doxorubicin conjugates for drug delivery
MX2011005963A (es) 2008-12-05 2011-09-01 Angiochem Inc Conjugados de neurotensina o analogos de neurotensina y sus usos.
US7862716B2 (en) * 2009-04-13 2011-01-04 Sielc Technologies Corporation HPLC schematic with integrated sample cleaning system
MX2011011023A (es) 2009-04-20 2012-01-20 Angiochem Inc Tratamiento de cancer de ovarios usando un agente anti-cancer conjugado con un analogo de angiopep-2.
CN102596993A (zh) 2009-07-02 2012-07-18 安吉奥开米公司 多聚体肽结合物以及其应用
FR2948568B1 (fr) * 2009-07-30 2012-08-24 Sanofi Aventis Formulation pharmaceutique
CN102151243B (zh) * 2010-12-29 2013-06-05 辰欣药业股份有限公司 一种紫杉醇注射液及其制备方法
CN103330941B (zh) * 2013-07-15 2014-11-19 贺金凤 一种紫杉醇注射剂的药物组合物
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
JP6823055B2 (ja) 2015-06-15 2021-01-27 アンジオケム インコーポレーテッド 軟髄膜癌腫症の治療方法
TWI715636B (zh) * 2015-09-30 2021-01-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法

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JPH07502274A (ja) * 1991-12-10 1995-03-09 ラシユ−プレスビタリアン−セントルークス・メデイカル・センター 多薬剤耐性を低下させる方法および組成物
CA2308082A1 (en) * 1992-11-27 1994-06-09 Paul Handreck Injectable compostion
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TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
AU702519B2 (en) * 1994-10-05 1999-02-25 Glaxo Wellcome Inc. Parenteral pharmaceutical compositions containing GF120918A
US5681846A (en) * 1995-03-17 1997-10-28 Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel
AU724842B2 (en) * 1995-12-21 2000-09-28 Genelabs Technologies, Inc. Taxane composition and method
EP0999826B1 (de) * 1997-07-29 2004-05-06 PHARMACIA & UPJOHN COMPANY Selbstemulgierbare formulierung enthaltend lipophile verbindungen

Also Published As

Publication number Publication date
DE69910230T2 (de) 2004-06-09
ATE246514T1 (de) 2003-08-15
DE69910230D1 (de) 2003-09-11
EP1117440A1 (de) 2001-07-25
ES2205879T3 (es) 2004-05-01
AU5822599A (en) 2000-04-26
US5922754A (en) 1999-07-13
CA2345729A1 (en) 2000-04-13
JP2002526424A (ja) 2002-08-20
AU759034B2 (en) 2003-04-03
WO2000020036A1 (en) 2000-04-13
PT1117440E (pt) 2003-12-31
EP1117440B1 (de) 2003-08-06

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