DK110885A - Nucleinsyre-proteinkonjugater, disses anvendelse samt fremgangsmaade til fremstilling heraf - Google Patents

Nucleinsyre-proteinkonjugater, disses anvendelse samt fremgangsmaade til fremstilling heraf Download PDF

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Publication number
DK110885A
DK110885A DK110885A DK110885A DK110885A DK 110885 A DK110885 A DK 110885A DK 110885 A DK110885 A DK 110885A DK 110885 A DK110885 A DK 110885A DK 110885 A DK110885 A DK 110885A
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DK
Denmark
Prior art keywords
preparing
nucleic acid
acid protein
protein conjugates
conjugates
Prior art date
Application number
DK110885A
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Danish (da)
English (en)
Other versions
DK110885D0 (da
Inventor
Nanibhushan Dattagupta
Vincent Marchesi
William Knowles
Donald M Crothers
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Publication of DK110885D0 publication Critical patent/DK110885D0/da
Publication of DK110885A publication Critical patent/DK110885A/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/964Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/828Protein A

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK110885A 1984-03-12 1985-03-11 Nucleinsyre-proteinkonjugater, disses anvendelse samt fremgangsmaade til fremstilling heraf DK110885A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/588,858 US4748111A (en) 1984-03-12 1984-03-12 Nucleic acid-protein conjugate used in immunoassay

Publications (2)

Publication Number Publication Date
DK110885D0 DK110885D0 (da) 1985-03-11
DK110885A true DK110885A (da) 1985-09-13

Family

ID=24355587

Family Applications (1)

Application Number Title Priority Date Filing Date
DK110885A DK110885A (da) 1984-03-12 1985-03-11 Nucleinsyre-proteinkonjugater, disses anvendelse samt fremgangsmaade til fremstilling heraf

Country Status (12)

Country Link
US (1) US4748111A (fi)
EP (1) EP0154884A3 (fi)
JP (1) JPS60226900A (fi)
AU (1) AU578933B2 (fi)
CA (1) CA1222706A (fi)
DK (1) DK110885A (fi)
ES (1) ES8606653A1 (fi)
FI (1) FI850925L (fi)
IL (1) IL74539A (fi)
NO (1) NO850769L (fi)
NZ (1) NZ211366A (fi)
ZA (1) ZA851797B (fi)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957858A (en) * 1986-04-16 1990-09-18 The Salk Instute For Biological Studies Replicative RNA reporter systems
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
US5384241A (en) * 1987-09-11 1995-01-24 Enzo Diagnostics, Inc. Specific binding assay compound with inhibitive self-quenching characteristics
DE3732145A1 (de) * 1987-09-24 1989-04-06 Merck Patent Gmbh Verfahren und reagenz zur durchfuehrung von hybridisierungsreaktionen
US5428132A (en) * 1987-10-11 1995-06-27 United States Of America Conjugate and method for integration of foreign DNA into cells
US5656731A (en) * 1987-10-15 1997-08-12 Chiron Corporation Nucleic acid-amplified immunoassay probes
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5525465A (en) * 1987-10-28 1996-06-11 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates and methods of production and applications of the same
JP2597698B2 (ja) * 1987-10-28 1997-04-09 ハワード・フローレイ・インスティテュト・オブ・イクスペリメンタル・フィジオロジー・アンド・メディシン オリゴヌクレオチド‐ポリアミド コンジュゲート
US4921788A (en) * 1988-04-12 1990-05-01 The Research Foundation Of State University Of New York Competitive nucleic acid immunoassay for the detection of analytes
US5109124A (en) * 1988-06-01 1992-04-28 Biogen, Inc. Nucleic acid probe linked to a label having a terminal cysteine
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US5763162A (en) 1990-03-14 1998-06-09 The Regents Of University Of California Multichromophore fluorescent DNA intercalation complexes
US5783687A (en) * 1990-03-14 1998-07-21 The Regents Of The University Of California Dyes designed for high sensitivity detection of double-stranded DNA
JPH05505526A (ja) * 1990-03-14 1993-08-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 多発光団蛍光プローブ
KR0171617B1 (ko) * 1990-05-04 1999-05-01 로버트 피.블랙비언 단백질-핵산 프로브 및 그를 사용하는 면역분석법
US5677440A (en) * 1990-07-16 1997-10-14 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates
EP0488152A3 (en) * 1990-11-30 1992-11-25 Hitachi, Ltd. Method for immunoassay and apparatus therefor
WO1992014758A1 (en) * 1991-02-13 1992-09-03 The Austin Research Institute Conjugate molecules
EP0646242A4 (en) * 1991-11-12 1997-12-03 Promega Corp NON-RADIOACTIVE ENZYME ASSAY.
JPH05149949A (ja) * 1991-11-26 1993-06-15 Nisshin Flour Milling Co Ltd 新規な微量物質測定法
US5747244A (en) * 1991-12-23 1998-05-05 Chiron Corporation Nucleic acid probes immobilized on polystyrene surfaces
EP1958646A1 (en) * 1992-02-11 2008-08-20 Henry M. Jackson Foundation For The Advancement Of Military Medicine Dual carrier immunogenic construct
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5354658A (en) * 1993-01-28 1994-10-11 Dennis Wright Non-radioactive method for detecting a labelled segment and a solution or composition therefor
JP3197277B2 (ja) * 1993-05-10 2001-08-13 日水製薬株式会社 一種類以上の免疫学的配位子の分析方法,その分析試薬およびそのキット
GB9404709D0 (en) * 1994-03-11 1994-04-27 Multilyte Ltd Binding assay
US5876924A (en) * 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
DK0774119T3 (da) * 1994-07-25 2004-07-12 Roche Diagnostics Gmbh Oligomere bæremolekyler med på defineret måde indföjede markeringsgrupper og haptener
SE504798C2 (sv) * 1995-06-16 1997-04-28 Ulf Landegren Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten
WO1997019193A2 (en) 1995-11-21 1997-05-29 Yale University Unimolecular segment amplification and detection
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
JP3130538B2 (ja) * 1996-06-10 2001-01-31 株式会社 分子バイオホトニクス研究所 高感度蛍光アッセイ
DE69739163D1 (de) * 1996-10-17 2009-01-22 Mitsubishi Chem Corp Molekül, welches Genotyp und Phänotyp zusammenführt und dessen Anwendungen
US6225074B1 (en) 1997-08-18 2001-05-01 Dennis Wright Direct chloramphenicol acetyl transferase assay
US6316229B1 (en) 1998-07-20 2001-11-13 Yale University Single molecule analysis target-mediated ligation of bipartite primers
AU770993B2 (en) * 1998-09-15 2004-03-11 Yale University Molecular cloning using rolling circle amplification
US6255082B1 (en) * 1998-09-15 2001-07-03 Yale University Artificial long terminal repeat vectors
US6203989B1 (en) * 1998-09-30 2001-03-20 Affymetrix, Inc. Methods and compositions for amplifying detectable signals in specific binding assays
US6232068B1 (en) * 1999-01-22 2001-05-15 Rosetta Inpharmatics, Inc. Monitoring of gene expression by detecting hybridization to nucleic acid arrays using anti-heteronucleic acid antibodies
FR2791141B1 (fr) * 1999-03-15 2001-06-01 Cis Bio Int Procede de reduction de l'extinction de fluorescence due au milieu de mesure
US6623926B1 (en) * 1999-06-01 2003-09-23 Phylos, Inc. Methods for producing 5′-nucleic acid-protein conjugates
US20060166227A1 (en) * 2000-06-20 2006-07-27 Stephen Kingsmore Protein expression profiling
US6323009B1 (en) * 2000-06-28 2001-11-27 Molecular Staging, Inc. Multiply-primed amplification of nucleic acid sequences
AU2001271722B2 (en) 2000-06-30 2006-04-13 Qiagen, Gmbh Signal amplification with lollipop probes
DE10041766A1 (de) * 2000-08-25 2002-03-14 Friz Biochem Gmbh Verfahren zur Markierung chemischer Substanzen
US6573051B2 (en) * 2001-03-09 2003-06-03 Molecular Staging, Inc. Open circle probes with intramolecular stem structures
US7553619B2 (en) * 2002-02-08 2009-06-30 Qiagen Gmbh Detection method using dissociated rolling circle amplification
US20040003559A1 (en) * 2002-04-24 2004-01-08 Minke Ronald C. Doors and methods of producing same
US7955795B2 (en) * 2003-06-06 2011-06-07 Qiagen Gmbh Method of whole genome amplification with reduced artifact production
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US6977153B2 (en) * 2002-12-31 2005-12-20 Qiagen Gmbh Rolling circle amplification of RNA
US8043834B2 (en) 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
EP1863908B1 (de) 2005-04-01 2010-11-17 Qiagen GmbH Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
WO2007044671A2 (en) * 2005-10-06 2007-04-19 Lucigen Corporation Thermostable viral polymerases and methods of use
US7811810B2 (en) 2007-10-25 2010-10-12 Industrial Technology Research Institute Bioassay system including optical detection apparatuses, and method for detecting biomolecules
US7767441B2 (en) 2007-10-25 2010-08-03 Industrial Technology Research Institute Bioassay system including optical detection apparatuses, and method for detecting biomolecules
US20100317020A1 (en) * 2008-02-14 2010-12-16 Roscoe Stephen B Methods and compositions for detecting microorganisms
KR101249273B1 (ko) * 2008-05-05 2013-04-01 다우 글로벌 테크놀로지스 엘엘씨 가요성 시트의 가장자리를 감싸는 개선된 방법
US9778188B2 (en) * 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
US9482615B2 (en) 2010-03-15 2016-11-01 Industrial Technology Research Institute Single-molecule detection system and methods
US8865077B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
US8865078B2 (en) 2010-06-11 2014-10-21 Industrial Technology Research Institute Apparatus for single-molecule detection
EP2972353B1 (en) 2013-03-11 2023-02-22 Meso Scale Technologies, LLC Improved methods for conducting multiplexed assays
CN109891218A (zh) * 2016-06-02 2019-06-14 乌尔蒂维尤股份有限公司 促进基于抗体的交换成像的组合物和方法
CN115060912B (zh) * 2022-06-23 2024-02-02 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
ES8307897A1 (es) * 1981-04-13 1983-08-01 Hoechst Co American Un metodo de determinar la presencia de un antigeno en un medio liquido sospechoso de contenerlo.
FR2519005B1 (fr) * 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
US4469787A (en) * 1982-05-14 1984-09-04 Mallinckrodt Inc. Immunoassay involving soluble complex of second antibody and labeled binding protein
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US4556643A (en) * 1982-07-26 1985-12-03 Agracetus Assay method and probe for polynucleotide sequences
GB8306426D0 (en) * 1983-03-09 1983-04-13 Malcolm A D B Detecting polynucleotide sequence
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4587044A (en) * 1983-09-01 1986-05-06 The Johns Hopkins University Linkage of proteins to nucleic acids

Also Published As

Publication number Publication date
CA1222706A (en) 1987-06-09
AU3943485A (en) 1985-09-19
JPS60226900A (ja) 1985-11-12
AU578933B2 (en) 1988-11-10
EP0154884A3 (en) 1988-11-30
NZ211366A (en) 1988-05-30
ZA851797B (en) 1985-11-27
ES8606653A1 (es) 1986-04-16
NO850769L (no) 1985-09-13
DK110885D0 (da) 1985-03-11
US4748111A (en) 1988-05-31
FI850925A0 (fi) 1985-03-08
EP0154884A2 (en) 1985-09-18
IL74539A0 (en) 1985-06-30
FI850925L (fi) 1985-09-13
ES541077A0 (es) 1986-04-16
IL74539A (en) 1989-01-31

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