DK1082410T3 - Humane CD45 - og/eller fibroblast mesenchymale stamceller - Google Patents

Humane CD45 - og/eller fibroblast mesenchymale stamceller

Info

Publication number
DK1082410T3
DK1082410T3 DK99926044T DK99926044T DK1082410T3 DK 1082410 T3 DK1082410 T3 DK 1082410T3 DK 99926044 T DK99926044 T DK 99926044T DK 99926044 T DK99926044 T DK 99926044T DK 1082410 T3 DK1082410 T3 DK 1082410T3
Authority
DK
Denmark
Prior art keywords
human
stem cells
mesenchymal stem
fibroblast
fibroblast mesenchymal
Prior art date
Application number
DK99926044T
Other languages
Danish (da)
English (en)
Inventor
Janice M Davis-Sproul
Mark Aaron Moorman
Donald William Jr Wa Simonetti
Renee Marie Mcneil
Lora Catherine Hammill
Stewart Craig
Original Assignee
Osiris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osiris Therapeutics Inc filed Critical Osiris Therapeutics Inc
Application granted granted Critical
Publication of DK1082410T3 publication Critical patent/DK1082410T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK99926044T 1998-05-29 1999-05-28 Humane CD45 - og/eller fibroblast mesenchymale stamceller DK1082410T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8712398P 1998-05-29 1998-05-29
PCT/US1999/011975 WO1999061587A1 (en) 1998-05-29 1999-05-28 Human cd45+ and/or fibroblast + mesenchymal stem cells

Publications (1)

Publication Number Publication Date
DK1082410T3 true DK1082410T3 (da) 2007-11-26

Family

ID=22203248

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99926044T DK1082410T3 (da) 1998-05-29 1999-05-28 Humane CD45 - og/eller fibroblast mesenchymale stamceller

Country Status (11)

Country Link
US (1) US6387367B1 (pt)
EP (1) EP1082410B1 (pt)
AT (1) ATE368731T1 (pt)
AU (1) AU4221399A (pt)
CA (1) CA2328524A1 (pt)
CY (1) CY1107778T1 (pt)
DE (1) DE69936720T2 (pt)
DK (1) DK1082410T3 (pt)
ES (1) ES2292245T3 (pt)
PT (1) PT1082410E (pt)
WO (1) WO1999061587A1 (pt)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7001746B1 (en) 1999-01-29 2006-02-21 Artecel Sciences, Inc. Methods and compositions for the differentiation of human preadipocytes into adipocytes
WO2000049136A1 (en) * 1999-02-17 2000-08-24 United States Surgical Genetically altered mesenchymal stem cells and methods of use thereof
US8062675B2 (en) 1999-07-07 2011-11-22 Angioblast Systems, Inc. Mesenchymal precursor cell
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US7670628B2 (en) * 1999-07-07 2010-03-02 Angioblast Systems, Inc. Mesenchymal precursor cell
US20050158289A1 (en) * 1999-07-07 2005-07-21 Simmons Paul J. Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals
US6555374B1 (en) 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
EP1918366A1 (en) 2000-02-26 2008-05-07 Artecel, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
US7078230B2 (en) 2000-02-26 2006-07-18 Artecel, Inc. Adipose tissue-derived stromal cell that expresses characteristics of a neuronal cell
US7582292B2 (en) 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
AU7493101A (en) * 2000-05-23 2001-12-03 Nexell Therapeutics Inc Reagents for cell selection and methods of use
US20030219445A1 (en) * 2000-05-23 2003-11-27 Nexell Therapeutics, Inc. Reagents for cell selection and methods of use
US6632620B1 (en) 2000-06-22 2003-10-14 Andrew N. Makarovskiy Compositions for identification and isolation of stem cells
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
ES2522890T3 (es) * 2000-12-06 2014-11-19 Anthrogenesis Corporation Método para recolectar células troncales placentarias
NZ527849A (en) * 2001-02-14 2006-09-29 Anthrogenesis Corp Post-partum mammalian placenta, its use and placental stem cells therefrom
CA2437957C (en) * 2001-02-14 2014-04-22 Robert J. Hariri Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
IL158622A0 (en) * 2001-04-30 2004-05-12 Yissum Res Dev Co Composite scaffolds and methods using same for generating complex tissue grafts
US20050064587A1 (en) * 2001-09-07 2005-03-24 Lawrence Rosenberg Pancreatic small cells and uses thereof
ATE464373T1 (de) * 2001-12-21 2010-04-15 Mount Sinai Hospital Corp Zelluläre zusammensetzungen und verfahren zur deren bereitung und verwendung
CN1281739C (zh) * 2002-02-19 2006-10-25 美迪宝斯特有限公司 从脐带血中分离并扩大培养间充质干细胞/祖细胞及将脐带血来源的间充质干细胞/祖细胞分化成各种间充质组织的方法
EP1551955A4 (en) * 2002-07-16 2006-11-29 Yissum Res Dev Co METHOD FOR IMPLANTING MESENCHYMAL STEM CELLS FOR TISSUE PAIRING AND FORMATION
US7470538B2 (en) * 2002-12-05 2008-12-30 Case Western Reserve University Cell-based therapies for ischemia
WO2004052177A2 (en) 2002-12-05 2004-06-24 Case Western Reserve University Cell-based therapies for ischemia
WO2004069172A2 (en) 2003-01-30 2004-08-19 The Government of the United States of America as represented by the Department of Veterans Affairs Multilineage-inducible cells and uses thereof
EP2335738A1 (en) * 2003-04-01 2011-06-22 United States Government as represented by the Department of Veteran's Affaires Stem-cell, precursor cell or target cell-based treatment of wound healing
ATE470199T1 (de) * 2003-04-24 2010-06-15 Koninkl Philips Electronics Nv Eingriffsfreie links-herzkammervolumenbestimmung
US20050014255A1 (en) * 2003-05-29 2005-01-20 Board Of Regents, The University Of Texas System Stem cells for clinical and commercial uses
EP1636341A4 (en) * 2003-05-29 2007-08-01 Univ Texas STEM CELLS FOR CLINICAL AND COMMERCIAL APPLICATIONS
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US8491883B2 (en) * 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
JP5148873B2 (ja) * 2003-06-27 2013-02-20 エチコン、インコーポレイテッド 臍帯組織由来の分娩後細胞、及びその作成及び使用方法
WO2006071794A2 (en) 2004-12-23 2006-07-06 Ethicon Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
US7744869B2 (en) * 2003-08-20 2010-06-29 Ebi, Llc Methods of treatment using electromagnetic field stimulated mesenchymal stem cells
US8043614B2 (en) * 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
AU2004280616A1 (en) * 2003-10-08 2005-04-21 Vet-Stem Inc. Methods of preparing and using stem cell compositions and kits comprising the same
WO2005046596A2 (en) * 2003-11-04 2005-05-26 University Of Maryland Baltimore Stem cell culture medium and method of using said medium and the cells
EP1576957A1 (en) 2004-03-18 2005-09-21 Universiteit Twente Tissue repair using pluripotent cells
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
CN101080486B (zh) * 2004-04-23 2012-05-16 佰欧益股份有限公司 多谱系祖细胞
ES2645012T3 (es) * 2004-09-24 2017-12-01 Mesoblast, Inc. Método para potenciar la proliferación y/o supervivencia de las células precursoras mesenquimales (MPC)
EP1851858B1 (en) * 2004-12-03 2016-06-08 New Jersey Institute of Technology Substrate recognition by differentiable human mesenchymal stem cells
WO2006060779A2 (en) * 2004-12-03 2006-06-08 Case Western Reserve University Novel methods, compositions and devices for inducing neovascularization
US20060166361A1 (en) * 2004-12-21 2006-07-27 Agnieszka Seyda Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
US20060153815A1 (en) * 2004-12-21 2006-07-13 Agnieszka Seyda Tissue engineering devices for the repair and regeneration of tissue
US20060171930A1 (en) * 2004-12-21 2006-08-03 Agnieszka Seyda Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
WO2006071802A2 (en) 2004-12-23 2006-07-06 Ethicon Incorporated Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells
CA2512667A1 (en) * 2005-01-07 2006-07-07 Takahiro Ochiya Human hepatocyte-like cells and uses thereof
BRPI0520280A2 (pt) * 2005-05-10 2009-04-28 Us Of America Dept Of Veteran terapia de disfunÇÕes renais e falÊncia méltipla de àrgços com cÉlulas-tronco mesenquimais e meio condicionado por exposiÇço a cÉlulas-tronco mesenquimais
US20070038298A1 (en) * 2005-06-30 2007-02-15 Sulner Joseph W Repair of tympanic membrane using placenta derived collagen biofabric
WO2007009062A2 (en) * 2005-07-13 2007-01-18 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
EP2796544B1 (en) 2005-09-09 2019-04-03 Duke University Tissue engineering methods and compositions
WO2008048671A1 (en) * 2006-10-18 2008-04-24 University Of Illinois Embryonic-like stem cells derived from adult human peripheral blood and methods of use
DK1957633T3 (en) 2005-10-13 2014-03-17 Anthrogenesis Corp Immunomodulation USING PLACE SPEECH STEM CELLS
US8268361B2 (en) 2005-10-26 2012-09-18 Ahlfors Jan-Eric W Acellular bioabsorbable tissue regeneration matrices
US8182444B2 (en) * 2005-11-04 2012-05-22 Medrad, Inc. Delivery of agents such as cells to tissue
US7713232B2 (en) 2005-11-04 2010-05-11 Medrad, Inc. System for washing and processing of cells for delivery thereof to tissue
US20070105769A1 (en) * 2005-11-07 2007-05-10 Ebi, L.P. Methods of treating tissue defects
US7521221B2 (en) * 2005-11-21 2009-04-21 Board Of Trustees Of The University Of Arknasas Staphylococcus aureus strain CYL1892
KR100697326B1 (ko) * 2005-12-02 2007-03-20 재단법인서울대학교산학협력재단 Ｏｃｔ４ 발현능을 가지는 제대혈 유래 다분화능 성체줄기세포 및 그의 제조방법
ES2642844T3 (es) * 2005-12-16 2017-11-20 DePuy Synthes Products, Inc. Composiciones y métodos para inhibir una respuesta inmune adversa en el trasplante de histocompatibilidad que no coinciden
US8741638B2 (en) * 2005-12-19 2014-06-03 DePuy Synthes Products, LLC In vitro expansion of postpartum-derived cells in roller bottles
WO2007076522A2 (en) * 2005-12-28 2007-07-05 Ethicon, Incorporated Treatment of peripheral vascular disease using postpartum-derived cells
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
JP2009521930A (ja) 2005-12-29 2009-06-11 アントフロゲネシス コーポレーション 胎盤幹細胞及び第２供給源由来幹細胞の共存培養
KR20190104428A (ko) 2005-12-29 2019-09-09 안트로제네시스 코포레이션 태반 줄기 세포 집단
EP2422800A3 (en) 2006-03-07 2013-03-06 Geeta Shroff Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
CA2646491A1 (en) * 2006-04-17 2007-10-25 Bioe, Inc. Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
WO2007143139A1 (en) * 2006-05-31 2007-12-13 The Brigham And Women's Hospital, Inc. Abcb5 positive mesenchymal stem cells as immunomodulators
JP2009539378A (ja) * 2006-06-09 2009-11-19 アントフロゲネシス コーポレーション 胎盤環境及び幹細胞を培養するためのその使用
US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
US8105634B2 (en) * 2006-08-15 2012-01-31 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
MX354253B (es) 2006-10-06 2018-02-20 Anthrogenesis Corp Composiciones de colageno placentario (telopeptido), natural.
CN104099290A (zh) 2006-10-23 2014-10-15 人类起源公司 用胎盘细胞群治疗骨缺损的方法和组合物
CA2913024A1 (en) * 2006-11-03 2008-05-08 Aastrom Biosciences, Inc. Mixed cell populations for tissue repair and separation technique for cell processing
US20080299097A1 (en) * 2006-11-08 2008-12-04 Tulane University Health Sciences Center Isolated population of rapidly proliferating marrow stromal cells for enhanced in vivo engraftment
WO2008085229A2 (en) * 2006-11-15 2008-07-17 Arteriocyte Inc. Cell-based therapies for treating liver disease
US8920305B2 (en) 2007-01-19 2014-12-30 Advanced Bariatric Technology, Llc Vertically oriented band for stomach
US8084023B2 (en) 2007-01-22 2011-12-27 The Board Of Trustees Of The University Of Arkansas Maintenance and propagation of mesenchymal stem cells
SI2120977T1 (sl) 2007-02-12 2014-01-31 Anthrogenesis Coroporation Zdravljenje vnetnih bolezni z uporabo placentarnih matičnih celic
CA2679178A1 (en) * 2007-02-26 2008-09-04 Mount Sinai Hospital Compositions and methods for treating peripheral vascular diseases
US8034014B2 (en) 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth
US20090028921A1 (en) 2007-06-18 2009-01-29 New Jersey Institute Of Technology Electrospun Ceramic-Polymer Composite As A Scaffold For Tissue Repair
WO2009015343A2 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of multi-lineage progenitor cells to chondrocytes
WO2009045360A2 (en) 2007-09-28 2009-04-09 Celgene Cellular Therapeutics Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
WO2009046335A1 (en) * 2007-10-05 2009-04-09 Ethicon, Incorporated Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells
WO2009073724A1 (en) * 2007-12-04 2009-06-11 Ingeneron, Inc. Apparatus and methods for cell isolation
US8236538B2 (en) 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
CN102026546A (zh) 2008-03-14 2011-04-20 再生科学有限责任公司 软骨修复的合成物和方法
US20090325296A1 (en) 2008-03-25 2009-12-31 New Jersey Institute Of Technology Electrospun electroactive polymers for regenerative medicine applications
US20110150845A1 (en) * 2008-05-02 2011-06-23 Massachusetts Institute Of Technology Methods and compositions for modulating immunological tolerance
WO2009143241A2 (en) * 2008-05-21 2009-11-26 Bioe, Inc. Differentiation of multi-lineage progenitor cells to pancreatic cells
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
US8828376B2 (en) 2008-08-20 2014-09-09 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
US8728805B2 (en) 2008-08-22 2014-05-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
US8865199B2 (en) * 2008-11-17 2014-10-21 Ingeneron, Inc. Biomatrix composition and methods of biomatrix seeding
RU2562154C2 (ru) 2008-11-19 2015-09-10 Антродженезис Корпорейшн Амниотические адгезивные клетки
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
US10179900B2 (en) * 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
CA2747794C (en) 2008-12-19 2018-10-30 Advanced Technologies And Regenerative Medicine, Llc Treatment of lung and pulmonary diseases and disorders
SI2379087T1 (sl) * 2008-12-19 2015-01-30 DePuy Synthes Products, LLC Celice, izpeljane iz popkovniäśnega tkiva, za zdravljenje nevropatske boleäśine in spastiäśnosti
JP6095893B2 (ja) * 2008-12-19 2017-03-15 デピュイ・シンセス・プロダクツ・インコーポレイテッド 傷害後の神経組織の再生および修復
US20100310527A1 (en) * 2009-01-09 2010-12-09 Board Of Regents Of The University Of Texas System Liposome mediated delivery of lineage determining factors
US9192655B2 (en) 2009-03-12 2015-11-24 New Jersey Institute Of Technology System and method for a hydrogel and hydrogel composite for cartilage repair applications
US9334476B2 (en) 2009-03-12 2016-05-10 New Jersey Institute Of Technology Method for nerve growth and repair using a piezoelectric scaffold
US9476026B2 (en) 2009-03-12 2016-10-25 New Jersey Institute Of Technology Method of tissue repair using a piezoelectric scaffold
US9771557B2 (en) 2009-03-12 2017-09-26 New Jersey Institute Of Technology Piezoelectric scaffold for nerve growth and repair
AU2010229651B2 (en) * 2009-03-26 2014-05-08 Advanced Technologies And Regenerative Medicine, Llc Human umbilical cord tissue cells as therapy for Alzheimer' s disease
US9301975B2 (en) 2009-05-01 2016-04-05 Biocardia, Inc. Method of preparing autologous cells and method of use for therapy
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
EP3284818B1 (en) 2010-01-26 2022-03-09 Celularity Inc. Treatment of bone-related cancers using placental stem cells
US9180166B2 (en) 2010-03-12 2015-11-10 New Jersey Institute Of Technology Cartilage repair systems and applications utilizing a glycosaminoglycan mimic
TW201902496A (zh) 2010-04-07 2019-01-16 美商安瑟吉納西斯公司 利用胎盤幹細胞之血管新生
AU2011237743A1 (en) 2010-04-08 2012-11-01 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
DK2561078T3 (en) 2010-04-23 2019-01-14 Cold Spring Harbor Laboratory NEW STRUCTURALLY DESIGNED SHRNAs
PL2576768T3 (pl) 2010-06-01 2017-10-31 Auxocell Laboratories Inc Oczyszczanie niehodowanych komórek macierzystych galarety Whartona
KR20190108599A (ko) 2010-07-13 2019-09-24 안트로제네시스 코포레이션 천연 킬러 세포의 생성 방법
DK2613776T3 (da) 2010-09-01 2020-10-19 Univ Jefferson Sammensætning og fremgangsmåde til muskelreparation og -regenerering
EP2614145B1 (en) 2010-09-07 2020-12-02 The Board of Regents of The University of Texas System Tissue-specific differentiation matrices and uses thereof
EP2625263B1 (en) 2010-10-08 2020-03-11 Terumo BCT, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012060517A1 (ko) * 2010-11-05 2012-05-10 하이스템(주) Ｃｄ45가 발현되는 중간엽 줄기세포를 유효성분으로 포함하는 신경질환 예방 및 치료용 의약 조성
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
US10081794B2 (en) 2011-04-13 2018-09-25 New Jersey Institute Of Technology System and method for electrospun biodegradable scaffold for bone repair
CN113559126A (zh) 2011-06-01 2021-10-29 人类起源公司 利用胎盘干细胞治疗疼痛
DK2729562T3 (en) 2011-07-06 2018-07-23 Cell Therapy Ltd Progenitor cells of mesodermal origin
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
CN104837987B (zh) 2011-12-23 2018-10-02 德普伊新特斯产品公司 人脐带组织来源的细胞的检测
ES2656614T3 (es) 2011-12-30 2018-02-27 Amit Patel Métodos y composiciones para la derivación clínica de células alogénicas y sus usos terapéuticos
GB201202319D0 (en) 2012-02-10 2012-03-28 Orbsen Therapeutics Ltd Stromal stem cells
MY184539A (en) 2012-08-09 2021-04-01 Advanced Bariatric Tech Llc Polymer overmolded bariatric clamp and method of installing
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
EP3865573A1 (en) 2013-02-19 2021-08-18 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
JP6600299B2 (ja) 2013-05-10 2019-10-30 ザ チルドレンズ メディカル センター コーポレーション 創傷治癒および組織工学
WO2015073918A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2015121380A1 (en) 2014-02-12 2015-08-20 National University Of Ireland, Galway Selection and use of stem cells
EP3122866B1 (en) 2014-03-25 2019-11-20 Terumo BCT, Inc. Passive replacement of media
EP3185784A4 (en) 2014-08-26 2018-09-12 Advanced Bariatric Technology LLC Bariatric clamp with suture portions, magnetic inserts and curvature
EP3198006B1 (en) 2014-09-26 2021-03-24 Terumo BCT, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (en) 2016-05-25 2020-01-01 Terumo BCT, Inc. CELL EXPANSION
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
EP3656842A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5654186A (en) * 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
US5591625A (en) * 1993-11-24 1997-01-07 Case Western Reserve University Transduced mesenchymal stem cells
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation

Also Published As

Publication number Publication date
CY1107778T1 (el) 2013-06-19
AU4221399A (en) 1999-12-13
WO1999061587A1 (en) 1999-12-02
PT1082410E (pt) 2007-11-09
EP1082410A1 (en) 2001-03-14
DE69936720D1 (de) 2007-09-13
EP1082410B1 (en) 2007-08-01
DE69936720T2 (de) 2008-04-30
US6387367B1 (en) 2002-05-14
ATE368731T1 (de) 2007-08-15
CA2328524A1 (en) 1999-12-02
ES2292245T3 (es) 2008-03-01

Similar Documents

Publication Publication Date Title
DK1082410T3 (da) Humane CD45 - og/eller fibroblast mesenchymale stamceller
DK1226233T3 (da) Multipotente voksne stamceller og fremgangsmåder til isolering heraf
BR9910251A (pt) Estimulação hematopoiética
MY135732A (en) 5,6-trimethylenepyrimidin - 4 - one compounds
HK1091228A1 (en) Methods for making recombinant proteins using apoptosis inhibitors
TR200103216T2 (tr) Pirimidinon bileşimleri
ATE265219T1 (de) Verwendung von cxcr4 antagonisten zur behandlung von krebs und autoimmunkrankheiten
NO20001583L (no) Stimulering av hematopoetiske celler in vitro
BR9811956A (pt) Naftiridinonas para a inibição de proteìna tirosina cinase e de proliferação celular mediada por cinase de ciclo de célula
DK0774005T3 (da) Overfladeudtrykkelse af enzymer i genorienteret prodrug-terapi
DE60132429D1 (de) Pluripotente stammzellen erzeugt aus stromalzellen aus dem fettgewebe und deren verwendungen
HUP0400689A2 (hu) ABCA-1 szint-emelő vegyületek
WO2006134602A3 (en) Isolated cells and populations comprising same for the treatment of cns diseases
TW200612918A (en) Lonidamine analogs
GB9807639D0 (en) Anti-inflammatory agents
BR0312764A (pt) Cardiomiócitos funcionais originados de células-tronco embrionárias humanas
EP1231914A4 (en) NORDIHYDROGUAIARTIC DERIVATIVES FOR USE IN THE TREATMENT OF TUMORS
IL148008A0 (en) Conditional immortalisation of cells
EP1233058A4 (en) PROCESS FOR THE REPRODUCTION OF NATURAL KILLER CELLS
ES2181461T3 (es) Utilizacion de nuevos agentes inductores de muerte celular en sinergia con interferones.
DE60039863D1 (de) Verwendung von zytokinen und mitogenen zur inhibierung von pathologischen immunantworten
DK0538330T3 (da) Beta-Alethin-anvendelse til celledyrkning og terapi
PT925064E (pt) 5-androsteno-3beta,17alfa-diol como um inibidor do crescimento tumoral
DK1196598T3 (da) DSP-3 phosphatase med dobbelt specificitet
AU8478601A (en) Methods for culturing human lung mast cells and uses thereof