DK1082128T3 - Lysinholdige peptider til behandling af hjertesygdom - Google Patents
Lysinholdige peptider til behandling af hjertesygdomInfo
- Publication number
- DK1082128T3 DK1082128T3 DK99926472T DK99926472T DK1082128T3 DK 1082128 T3 DK1082128 T3 DK 1082128T3 DK 99926472 T DK99926472 T DK 99926472T DK 99926472 T DK99926472 T DK 99926472T DK 1082128 T3 DK1082128 T3 DK 1082128T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptides
- lysine
- present
- cardiac
- treatment
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004472 Lysine Substances 0.000 title abstract 2
- 208000019622 heart disease Diseases 0.000 title abstract 2
- 230000000747 cardiac effect Effects 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 210000005003 heart tissue Anatomy 0.000 abstract 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
- 239000000816 peptidomimetic Substances 0.000 abstract 1
- 230000002633 protecting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/089,955 US5932548A (en) | 1998-06-03 | 1998-06-03 | Lysine containing peptides for treatment of heart disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1082128T3 true DK1082128T3 (da) | 2006-04-10 |
Family
ID=22220375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99926472T DK1082128T3 (da) | 1998-06-03 | 1999-05-28 | Lysinholdige peptider til behandling af hjertesygdom |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5932548A (https=) |
| EP (2) | EP1082128B1 (https=) |
| JP (1) | JP2002516872A (https=) |
| AT (1) | ATE314083T1 (https=) |
| AU (1) | AU4371799A (https=) |
| CA (1) | CA2330567A1 (https=) |
| DE (1) | DE69929188T2 (https=) |
| DK (1) | DK1082128T3 (https=) |
| ES (1) | ES2259834T3 (https=) |
| PT (1) | PT1082128E (https=) |
| WO (1) | WO1999062539A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1783222E (pt) | 1998-10-23 | 2012-07-26 | Kirin Amgen Inc | Péptidos diméricos de trombopoietina que simulam a ligação ao receptor mpl e têm actividade trombopoiética |
| US7488590B2 (en) | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
| US20030130185A1 (en) * | 2000-09-29 | 2003-07-10 | David Bar-Or | Metal-binding compounds and uses therefor |
| US7632803B2 (en) * | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US6211156B1 (en) * | 1999-11-10 | 2001-04-03 | Asta Medica A.G. | Peptides for treatment of erectile dysfunction |
| JP3498041B2 (ja) | 2000-05-29 | 2004-02-16 | 科研製薬株式会社 | プラルモレリン含有点鼻用製剤 |
| AU2001274601A1 (en) * | 2000-06-23 | 2002-01-02 | Kaken Pharmaceutical Co., Ltd. | Preventives or remedies for heart failure |
| US20030055003A1 (en) * | 2001-07-19 | 2003-03-20 | David Bar-Or | Use of copper chelators to inhibit the inactivation of protein C |
| TWI331922B (en) * | 2002-08-09 | 2010-10-21 | Ipsen Pharma Sas | Growth hormone releasing peptides |
| BRPI0410505A (pt) * | 2003-05-07 | 2006-06-20 | Dmi Biosciences Inc | métodos e produtos para cuidados orais |
| EA011879B1 (ru) | 2004-09-24 | 2009-06-30 | Эмджин Инк. | МОЛЕКУЛЫ С МОДИФИЦИРОВАННЫМ Fc ФРАГМЕНТОМ |
| US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
| GB0603295D0 (en) | 2006-02-18 | 2006-03-29 | Ardana Bioscience Ltd | Methods and kits |
| US9283260B2 (en) | 2006-04-21 | 2016-03-15 | Amgen Inc. | Lyophilized therapeutic peptibody formulations |
| WO2007127457A2 (en) * | 2006-04-28 | 2007-11-08 | The Administrators Of The Tulane Educational Fund | Ghrelin/growth hormone releasing peptide/growth hormone secretatogue receptor antagonists and uses thereof |
| TW200916113A (en) * | 2007-08-08 | 2009-04-16 | Sod Conseils Rech Applic | Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue |
| GB2454549B (en) * | 2007-09-25 | 2009-09-23 | Medical & Pharm Ind Tech & Dev | Uses of 2-[piperidinyl]methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one for providing an anti-allergic effect and histamine H1 receptor antagonism effect |
| US8476408B2 (en) * | 2008-06-13 | 2013-07-02 | Alize Pharma Sas | Unacylated ghrelin and analogs as therapeutic agents for vascular remodeling in diabetic patients and treatment of cardiovascular disease |
| EP2341942A1 (en) | 2008-09-19 | 2011-07-13 | Nektar Therapeutics | Polymer conjugates of therapeutic peptides |
| US9724381B2 (en) | 2009-05-12 | 2017-08-08 | The Administrators Of The Tulane Educational Fund | Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof |
| RU2404793C1 (ru) | 2009-06-04 | 2010-11-27 | Общество с ограниченной ответственностью Био Пептид | Стимулятор половой, сексуальной и репродуктивной функции |
| RU2507212C3 (ru) | 2012-03-28 | 2022-05-04 | Общество С Ограниченной Ответственностью "Айвикс" | Способ получения рекомбинантного пептида и полученный пептид |
| RU2626002C1 (ru) | 2016-10-24 | 2017-07-21 | Общество С Ограниченной Ответственностью "Айвикс" | Новая группа пептидов для лечения женской сексуальной дисфункции |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5668254A (en) * | 1990-05-11 | 1997-09-16 | Romano Deghenghi | D-2-alkyl-tryptophan and peptides containing same |
| US5661122A (en) * | 1994-04-15 | 1997-08-26 | Genentech, Inc. | Treatment of congestive heart failure |
| JP3810083B2 (ja) * | 1994-09-27 | 2006-08-16 | アーダナ・バイオサイエンス・リミテツド | 成長因子の放出を促進し得る２−アルキルトリプトファン含有ペプチド化合物 |
| US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
| IT1277113B1 (it) * | 1995-12-20 | 1997-11-04 | Romano Deghenghi | Composti oligopeptidici contenenti d-2-alchiltriptofano in grado di promuovere la liberazione dell'ormone della crescita |
| SE9703929D0 (sv) * | 1996-11-22 | 1997-10-28 | Pharmacia & Upjohn Ab | Therapeutical use and method |
| US5798102A (en) * | 1997-03-04 | 1998-08-25 | Milkhaus Laboratory, Inc. | Treatment of cardiomyopathy |
| ZA987383B (en) * | 1997-08-19 | 2000-02-17 | Lilly Co Eli | Treatment of congestive heart failure with growth hormone secretagogues. |
-
1998
- 1998-06-03 US US09/089,955 patent/US5932548A/en not_active Expired - Fee Related
-
1999
- 1999-05-28 DE DE69929188T patent/DE69929188T2/de not_active Expired - Fee Related
- 1999-05-28 AU AU43717/99A patent/AU4371799A/en not_active Abandoned
- 1999-05-28 CA CA002330567A patent/CA2330567A1/en not_active Abandoned
- 1999-05-28 EP EP99926472A patent/EP1082128B1/en not_active Expired - Lifetime
- 1999-05-28 ES ES99926472T patent/ES2259834T3/es not_active Expired - Lifetime
- 1999-05-28 WO PCT/EP1999/003731 patent/WO1999062539A1/en not_active Ceased
- 1999-05-28 AT AT99926472T patent/ATE314083T1/de not_active IP Right Cessation
- 1999-05-28 PT PT99926472T patent/PT1082128E/pt unknown
- 1999-05-28 JP JP2000551795A patent/JP2002516872A/ja active Pending
- 1999-05-28 EP EP04077333A patent/EP1616571A3/en not_active Withdrawn
- 1999-05-28 DK DK99926472T patent/DK1082128T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69929188T2 (de) | 2006-08-17 |
| CA2330567A1 (en) | 1999-12-09 |
| HK1035863A1 (en) | 2001-12-14 |
| ATE314083T1 (de) | 2006-01-15 |
| JP2002516872A (ja) | 2002-06-11 |
| EP1082128A1 (en) | 2001-03-14 |
| DE69929188D1 (de) | 2006-02-02 |
| EP1082128B1 (en) | 2005-12-28 |
| WO1999062539A1 (en) | 1999-12-09 |
| PT1082128E (pt) | 2006-05-31 |
| EP1616571A2 (en) | 2006-01-18 |
| ES2259834T3 (es) | 2006-10-16 |
| US5932548A (en) | 1999-08-03 |
| AU4371799A (en) | 1999-12-20 |
| EP1616571A3 (en) | 2008-08-13 |
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