DK1079851T3 - Anvendelse af anti-prolactinmidler til behandling af cancer - Google Patents
Anvendelse af anti-prolactinmidler til behandling af cancerInfo
- Publication number
- DK1079851T3 DK1079851T3 DK99921843T DK99921843T DK1079851T3 DK 1079851 T3 DK1079851 T3 DK 1079851T3 DK 99921843 T DK99921843 T DK 99921843T DK 99921843 T DK99921843 T DK 99921843T DK 1079851 T3 DK1079851 T3 DK 1079851T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- cancer
- prolactin
- agents
- prolactin agents
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 230000001263 anti-prolactin effect Effects 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 101000687438 Homo sapiens Prolactin Proteins 0.000 abstract 1
- 108010002519 Prolactin Receptors Proteins 0.000 abstract 1
- 102100029000 Prolactin receptor Human genes 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 210000002307 prostate Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2257—Prolactin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8512898P | 1998-05-12 | 1998-05-12 | |
US24604199A | 1999-02-05 | 1999-02-05 | |
PCT/US1999/010232 WO1999058142A1 (fr) | 1998-05-12 | 1999-05-11 | Utilisation d'agents anti-prolactine pour le traitement d'etats proliferatifs |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1079851T3 true DK1079851T3 (da) | 2007-09-24 |
Family
ID=26772335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99921843T DK1079851T3 (da) | 1998-05-12 | 1999-05-11 | Anvendelse af anti-prolactinmidler til behandling af cancer |
Country Status (11)
Country | Link |
---|---|
US (2) | US7115556B2 (fr) |
EP (2) | EP1079851B1 (fr) |
JP (4) | JP5259896B2 (fr) |
AT (1) | ATE366114T1 (fr) |
AU (1) | AU3895299A (fr) |
CA (1) | CA2328520C (fr) |
DE (1) | DE69936451T2 (fr) |
DK (1) | DK1079851T3 (fr) |
ES (1) | ES2288777T3 (fr) |
PT (1) | PT1079851E (fr) |
WO (1) | WO1999058142A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004504272A (ja) | 2000-03-23 | 2004-02-12 | グリーンビル ホスピタル システム | 双機能癌治療剤 |
ATE468104T1 (de) * | 2002-06-12 | 2010-06-15 | Oreal | Mit silikonpolymeren und organischen geliermitteln strukturierte pflege- und/oder- makeup-zusammensetzung in starrer form |
US6995244B2 (en) | 2002-12-13 | 2006-02-07 | The Ohio State University | Antagonists for human prolactin |
GEP20084486B (en) | 2002-12-26 | 2008-09-25 | Mountain View Pharmaceuticals | Polymer conjugates of interferon-beta with enhanced biological potency |
US8754031B2 (en) * | 2004-03-08 | 2014-06-17 | Oncolix, Inc. | Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway |
US7507716B2 (en) * | 2005-07-06 | 2009-03-24 | Board Of Regents, The University Of Texas System | Method for treating pain with prolactin antagonists |
WO2008028684A2 (fr) * | 2006-09-08 | 2008-03-13 | Novo Nordisk A/S | Peptides présentant une affinité élevée avec le récepteur de la prolactine |
WO2008114077A1 (fr) * | 2007-03-20 | 2008-09-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Mutants constitutivement actifs du recepteur de la prolactine |
EP2167116A2 (fr) * | 2007-07-05 | 2010-03-31 | Novo Nordisk A/S | Peptides ayant une forte affinite pour le recepteut de la prolactine |
WO2009135056A2 (fr) * | 2008-04-30 | 2009-11-05 | Monsanto Technology Llc | Vecteurs d’adn recombiné destinés à l’expression d’antagonistes de la prolactine humaine |
US8648046B2 (en) | 2009-02-26 | 2014-02-11 | Oncolix, Inc. | Compositions and methods for visualizing and eliminating cancer stem cells |
JP5963443B2 (ja) * | 2009-02-26 | 2016-08-03 | オンコリックス, インコーポレイテッド | がん幹細胞を可視化・排除するための組成物および方法 |
CA2788640A1 (fr) * | 2010-02-03 | 2011-08-11 | Orbis Health Solutions Llc | Procede de sensibilisation de cellules a un traitement contre le cancer |
US9545451B2 (en) | 2013-08-21 | 2017-01-17 | Regeneron Pharmaceuticals, Inc. | Anti-PRLR antibodies and methods for killing PRLR-expressing cells |
TWI641620B (zh) | 2013-08-21 | 2018-11-21 | 再生元醫藥公司 | 抗-prlr抗體及其用途 |
KR20190091290A (ko) | 2016-11-29 | 2019-08-05 | 리제너론 파아마슈티컬스, 인크. | Prlr 양성 유방암 치료 방법 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4833516A (en) * | 1987-08-03 | 1989-05-23 | International Business Machines Corporation | High density memory cell structure having a vertical trench transistor self-aligned with a vertical trench capacitor and fabrication methods therefor |
US5350836A (en) | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
US6429186B1 (en) | 1991-05-10 | 2002-08-06 | Genentech, Inc. | Ligand antagonists for treatment of breast cancer |
DE69231467T2 (de) | 1991-05-10 | 2001-01-25 | Genentech, Inc. | Auswählen von agonisten und antagonisten von liganden |
US5590656A (en) * | 1992-09-15 | 1997-01-07 | The Ohio State University Research Foundation | Application of peptide/cell receptor kinetics utilizing radiolabeled somatostatin congeners in the in situ, in vivo detection and differentiation of neoplastic tissue |
DE4231297A1 (de) | 1992-09-18 | 1994-03-24 | Basf Ag | Verfahren zur Herstellung von 3-(2'-Oxyethyl)-dihydro-2-(3H)furanonen |
CA2154163C (fr) * | 1993-02-19 | 2009-12-01 | Germaine Fuh | Antagonistes de ligands pour le traitement du cancer du sein |
KR100293867B1 (ko) * | 1994-04-06 | 2001-09-17 | 니뽄 신야쿠 가부시키가이샤 | 아미노스틸바졸유도체및의약 |
DE19718721C2 (de) * | 1997-05-02 | 1999-10-07 | Siemens Ag | DRAM-Zellenanordnung und Verfahren zu deren Herstellung |
-
1999
- 1999-05-11 AT AT99921843T patent/ATE366114T1/de active
- 1999-05-11 DK DK99921843T patent/DK1079851T3/da active
- 1999-05-11 EP EP99921843A patent/EP1079851B1/fr not_active Revoked
- 1999-05-11 EP EP10010603A patent/EP2316467A1/fr not_active Withdrawn
- 1999-05-11 ES ES99921843T patent/ES2288777T3/es not_active Expired - Lifetime
- 1999-05-11 WO PCT/US1999/010232 patent/WO1999058142A1/fr active IP Right Grant
- 1999-05-11 AU AU38952/99A patent/AU3895299A/en not_active Abandoned
- 1999-05-11 PT PT99921843T patent/PT1079851E/pt unknown
- 1999-05-11 JP JP2000547993A patent/JP5259896B2/ja not_active Expired - Lifetime
- 1999-05-11 DE DE69936451T patent/DE69936451T2/de not_active Expired - Lifetime
- 1999-05-11 CA CA2328520A patent/CA2328520C/fr not_active Expired - Lifetime
-
2002
- 2002-05-08 US US10/140,293 patent/US7115556B2/en not_active Expired - Lifetime
-
2006
- 2006-08-04 US US11/498,962 patent/US20070060520A1/en not_active Abandoned
-
2010
- 2010-10-01 JP JP2010223963A patent/JP2011079821A/ja not_active Withdrawn
-
2011
- 2011-07-05 JP JP2011149371A patent/JP5453355B2/ja not_active Expired - Lifetime
-
2013
- 2013-06-18 JP JP2013127119A patent/JP2013224309A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE69936451D1 (de) | 2007-08-16 |
WO1999058142A1 (fr) | 1999-11-18 |
ES2288777T3 (es) | 2008-01-16 |
US20030022833A1 (en) | 2003-01-30 |
CA2328520C (fr) | 2013-06-25 |
JP2012020996A (ja) | 2012-02-02 |
AU3895299A (en) | 1999-11-29 |
US20070060520A1 (en) | 2007-03-15 |
CA2328520A1 (fr) | 1999-11-18 |
PT1079851E (pt) | 2007-10-08 |
JP2013224309A (ja) | 2013-10-31 |
ATE366114T1 (de) | 2007-07-15 |
EP1079851A1 (fr) | 2001-03-07 |
WO1999058142A9 (fr) | 2000-02-10 |
JP2002515404A (ja) | 2002-05-28 |
US7115556B2 (en) | 2006-10-03 |
JP5453355B2 (ja) | 2014-03-26 |
JP2011079821A (ja) | 2011-04-21 |
EP1079851B1 (fr) | 2007-07-04 |
DE69936451T2 (de) | 2008-03-13 |
JP5259896B2 (ja) | 2013-08-07 |
EP2316467A1 (fr) | 2011-05-04 |
EP1079851A4 (fr) | 2004-03-17 |
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