DK1077072T3 - In vitro-fremgangsmåde til fremstilling af en homolog hjerteklap- eller karprotese - Google Patents
In vitro-fremgangsmåde til fremstilling af en homolog hjerteklap- eller karproteseInfo
- Publication number
- DK1077072T3 DK1077072T3 DK00108986T DK00108986T DK1077072T3 DK 1077072 T3 DK1077072 T3 DK 1077072T3 DK 00108986 T DK00108986 T DK 00108986T DK 00108986 T DK00108986 T DK 00108986T DK 1077072 T3 DK1077072 T3 DK 1077072T3
- Authority
- DK
- Denmark
- Prior art keywords
- homologous
- matrix
- cardiac
- producing
- vitro method
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/12—Pulsatile flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Developmental Biology & Embryology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Manufacturing & Machinery (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19919625A DE19919625C2 (de) | 1999-04-29 | 1999-04-29 | In-vitro-Verfahren zum Herstellen einer homologen Herzklappe und durch dieses Verfahren herstellbare Klappe |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1077072T3 true DK1077072T3 (da) | 2004-03-22 |
Family
ID=7906358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00108986T DK1077072T3 (da) | 1999-04-29 | 2000-04-27 | In vitro-fremgangsmåde til fremstilling af en homolog hjerteklap- eller karprotese |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1077072B8 (da) |
AT (1) | ATE253948T1 (da) |
DE (2) | DE19919625C2 (da) |
DK (1) | DK1077072T3 (da) |
ES (1) | ES2209715T3 (da) |
PT (1) | PT1077072E (da) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6576019B1 (en) | 1997-10-31 | 2003-06-10 | Children's Medical Center Corporation | Bladder reconstruction |
DE10058240A1 (de) * | 2000-11-17 | 2002-05-29 | Auto Tissue Gmbh | Verfahren und Vorrichtung zur Herstellung biologischer Prothesen |
DE10123139B4 (de) * | 2001-04-30 | 2005-08-11 | Berlin Heart Ag | Verfahren zur Regelung einer Unterstützungspumpe für Fluidfördersysteme mit pulsatilem Druck |
BR0214217A (pt) * | 2001-11-16 | 2004-09-21 | Childrens Medical Center | Aumento de função de órgão |
DE10235237A1 (de) * | 2002-08-01 | 2004-02-12 | Symetis Ag | In-vitro-Verfahren zum Herstellen einer homologen "gestenteten" Tissue eingineerten Herzklappe |
EP1452189A1 (de) * | 2003-02-28 | 2004-09-01 | Eidgenössische Technische Hochschule (ETH) | Implantatkörper mit Multiblock-Copolymerbeschichtung |
EP1452190A1 (de) * | 2003-02-28 | 2004-09-01 | Eidgenössische Technische Hochschule (ETH) | Implantatkörper mit Multiblock-Copolymer- und Polylysin-Beschichtung |
DE10322024A1 (de) | 2003-05-16 | 2004-12-02 | Symetis Ag | Bioreaktor zum Herstellen einer Gewebeprothese, insbesondere Herzklappe |
DE10327904B3 (de) * | 2003-06-20 | 2004-07-29 | Universitätsklinikum Schleswig-Holstein | Verfahren zur Herstellung biologischer Herzklappenprothesen |
DE10350287A1 (de) * | 2003-10-24 | 2005-05-25 | Deutsche Institute für Textil- und Faserforschung Stuttgart - Stiftung des öffentlichen Rechts | Kardiovaskuläres Implantat, Verfahren und Vorrichtung zur Herstellung und Bereitstellung für die Chirurgie |
GB0410177D0 (en) * | 2004-05-07 | 2004-06-09 | Univ Wales Medicine | Engineered tubular tissue structures |
EP1693025A1 (en) | 2005-02-17 | 2006-08-23 | Universität Zürich | Method of manufacturing a tissue-engineered prosthesis |
US7531503B2 (en) | 2005-03-11 | 2009-05-12 | Wake Forest University Health Sciences | Cell scaffold matrices with incorporated therapeutic agents |
US9248015B2 (en) | 2005-03-11 | 2016-02-02 | Wake Forest University Health Services | Production of tissue engineered heart valves |
US8728463B2 (en) | 2005-03-11 | 2014-05-20 | Wake Forest University Health Science | Production of tissue engineered digits and limbs |
US20060204539A1 (en) | 2005-03-11 | 2006-09-14 | Anthony Atala | Electrospun cell matrices |
CA2602029C (en) | 2005-03-11 | 2014-07-15 | Wake Forest University Health Sciences | Tissue engineered blood vessels |
DE102005049905A1 (de) * | 2005-10-17 | 2007-04-19 | Medizinische Hochschule Hannover | Verfahren und Vorrichtung zur Herstellung eines Gelenkersatzes |
EP2267114B1 (en) | 2005-10-28 | 2014-03-12 | Universität Zürich | Tissue engineering using pure populations of isolated non-embryoblastic fetal cells |
US9580688B2 (en) | 2007-06-08 | 2017-02-28 | Wake Forest University Health Sciences | Kidney structures and methods of forming the same |
ES2725502T3 (es) | 2007-06-08 | 2019-09-24 | Univ Wake Forest Health Sciences | Terapia celular selectiva para el tratamiento de la insuficiencia renal |
EP2130905A1 (en) | 2008-06-04 | 2009-12-09 | Pharmacell B.V. | Method for culturing eukaryotic cells |
WO2011098367A2 (en) | 2010-02-12 | 2011-08-18 | Universität Zürich | Method for in-vitro production of tissue engineered auto- and allografts suitable for guarded cryopreservation |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
EP2399986A1 (en) | 2010-06-22 | 2011-12-28 | Ludwig-Maximilians-Universität München | Bioreactor and method for creating and/or conditioning biological tissues |
DE102010026369B4 (de) | 2010-07-07 | 2015-07-30 | Zellwerk Gmbh | Verfahren und Druck-Drehbett-Bioreaktor zur dynamischen Expansion und/oder Differenzierung von Stammzellen oder primären Zellen humanen und tierischen Ursprungs |
EP2468846A1 (en) | 2010-12-22 | 2012-06-27 | Ludwig-Maximilians-Universität München | A method of examining tissue growth and conditioning of cells on a scaffold and a perfusion bioreactor |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
CZ2012376A3 (cs) * | 2012-06-05 | 2013-12-18 | Institut Klinické A Experimentální Medicíny | Způsob výroby perikardiální náhrady srdeční chlopně, perikardiální náhrada srdeční chlopně vyrobená tímto způsobem, zařízení pro kondicioning a modifikaci tkáně autologního perikardu pro perikardiální náhradu srdeční chlopně |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US10092679B2 (en) | 2013-10-18 | 2018-10-09 | Wake Forest University Health Sciences | Laminous vascular constructs combining cell sheet engineering and electrospinning technologies |
DE102015111126A1 (de) * | 2015-07-09 | 2017-01-12 | Medizinische Hochschule Hannover | Verfahren zur Herstellung eines bioartifiziellen, primär azellulären Konstrukts auf Fibrinbasis und dieses Konstrukt selbst |
CN108882981B (zh) | 2016-01-29 | 2021-08-10 | 内奥瓦斯克迪亚拉公司 | 用于防止流出阻塞的假体瓣膜 |
WO2018090148A1 (en) | 2016-11-21 | 2018-05-24 | Neovasc Tiara Inc. | Methods and systems for rapid retraction of a transcatheter heart valve delivery system |
CA3073834A1 (en) | 2017-08-25 | 2019-02-28 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US11737872B2 (en) | 2018-11-08 | 2023-08-29 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
WO2020150107A1 (en) * | 2019-01-16 | 2020-07-23 | University Of Florida Research Foundation | Bioreactor chamber and systems thereof |
CA3127232A1 (en) * | 2019-02-04 | 2020-08-13 | Edwards Lifesciences Corporation | Reinforced regenerative heart valves |
CA3135753C (en) | 2019-04-01 | 2023-10-24 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
EP3952792A4 (en) | 2019-04-10 | 2023-01-04 | Neovasc Tiara Inc. | HEART VALVE PROSTHESIS WITH NATURAL BLOOD FLOW |
AU2020279750B2 (en) | 2019-05-20 | 2023-07-13 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
AU2020295566B2 (en) | 2019-06-20 | 2023-07-20 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994025584A1 (en) * | 1993-04-28 | 1994-11-10 | Johns Hopkins University School Of Medicine | Chronic endothelial cell culture under flow |
AU1931495A (en) * | 1994-03-14 | 1995-10-03 | Cryolife, Inc. | Treated tissue for implantation and preparation methods |
US5792603A (en) * | 1995-04-27 | 1998-08-11 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts |
US5855610A (en) * | 1995-05-19 | 1999-01-05 | Children's Medical Center Corporation | Engineering of strong, pliable tissues |
AU5990696A (en) * | 1995-06-07 | 1996-12-30 | St. Jude Medical Inc. | Method for spatially positioning cells within a three-dimens ional matrix |
JP2002507907A (ja) * | 1997-06-27 | 2002-03-12 | バーダー、アウグスチヌス | 生合成移植片及びその製造方法 |
-
1999
- 1999-04-29 DE DE19919625A patent/DE19919625C2/de not_active Expired - Fee Related
-
2000
- 2000-04-27 AT AT00108986T patent/ATE253948T1/de not_active IP Right Cessation
- 2000-04-27 DE DE50004406T patent/DE50004406D1/de not_active Expired - Lifetime
- 2000-04-27 PT PT00108986T patent/PT1077072E/pt unknown
- 2000-04-27 EP EP00108986A patent/EP1077072B8/de not_active Expired - Lifetime
- 2000-04-27 DK DK00108986T patent/DK1077072T3/da active
- 2000-04-27 ES ES00108986T patent/ES2209715T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE19919625A1 (de) | 2000-11-30 |
EP1077072B8 (de) | 2004-04-14 |
EP1077072A3 (de) | 2001-06-27 |
ES2209715T3 (es) | 2004-07-01 |
DE19919625C2 (de) | 2002-10-31 |
EP1077072B1 (de) | 2003-11-12 |
PT1077072E (pt) | 2004-04-30 |
ATE253948T1 (de) | 2003-11-15 |
DE50004406D1 (de) | 2003-12-18 |
EP1077072A2 (de) | 2001-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1077072T3 (da) | In vitro-fremgangsmåde til fremstilling af en homolog hjerteklap- eller karprotese | |
ATE367833T1 (de) | IN-VITRO-VERFAHREN ZUM HERSTELLEN EINER HOMOLOGEN ßGESTENTETENß TISSUE ENGINEERTEN HERZKLAPPE | |
CN101066477B (zh) | 能在体捕获内皮祖细胞的生物人工血管 | |
ATE265191T1 (de) | Herstellungsverfahren von gewebe zur implantation | |
DE60037909D1 (de) | Rekonstruktion von organen aus einem dezellularisierten biologischem gerüst | |
EP1228773A4 (en) | TRANSPLANT MATERIAL AND A PRODUCTION METHOD THEREFOR | |
AU8476698A (en) | Human mesenchymal stem cells from peripheral blood | |
Ito et al. | Effect of coacervated α-elastin on proliferation of vascular smooth muscle and endothelial cells | |
ATE314102T1 (de) | Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration | |
CN101792735B (zh) | 含色素的人工皮肤检测模型及其制备方法 | |
CA2432416A1 (en) | Method of creating biological and biosynthetic material for implantation | |
CN101773687A (zh) | 一种复合软组织补片的制备方法 | |
CN101327338B (zh) | 多孔的保留有生物活性因子的膀胱无细胞基质及制备方法 | |
CA2410622A1 (en) | Method for producing of a bio-artificial transplant | |
Mian et al. | Stimulating effect of an arteriovenous shunt on the in vivo growth of isografted fibroblasts: a preliminary report | |
US20020099440A1 (en) | Individual vein valve prosthesis | |
ATE382378T1 (de) | Implantatmaterial | |
ATE206936T1 (de) | Autologe epithelialisierung bzw. endothelialisierung von hohlorganen bzw. gefässen | |
CN107715179A (zh) | 复合型人工小血管支架及其制备方法 | |
CN106834119A (zh) | 轴型血管化组织瓣培育器 | |
Kim et al. | Tissue-engineered acellularized valve xenografts: a comparative animal study between plain acellularized xenografts and autologous endothelial cell seeded acellularized xenografts | |
CN110215541A (zh) | 一种管状细菌纳米纤维素/鱼源明胶复合材料及其制备方法和人工血管应用 | |
DE50113506D1 (de) | Verfahren zur herstellung eines empfängerspezifischen gewebe-transplantats oder -implantats | |
CN1651572A (zh) | 体外构建组织工程化血管的方法 | |
Tien et al. | Engineering of blood vessels |