DK1073415T3 - Gelerbare farmaceutiske sammensætninger - Google Patents

Gelerbare farmaceutiske sammensætninger

Info

Publication number
DK1073415T3
DK1073415T3 DK99923418T DK99923418T DK1073415T3 DK 1073415 T3 DK1073415 T3 DK 1073415T3 DK 99923418 T DK99923418 T DK 99923418T DK 99923418 T DK99923418 T DK 99923418T DK 1073415 T3 DK1073415 T3 DK 1073415T3
Authority
DK
Denmark
Prior art keywords
weight
gellable
pharmaceutical compositions
active substance
composition
Prior art date
Application number
DK99923418T
Other languages
Danish (da)
English (en)
Inventor
Domenico Fanara
Michel Deleers
Henri Vranckx
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Application granted granted Critical
Publication of DK1073415T3 publication Critical patent/DK1073415T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1274Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK99923418T 1998-04-30 1999-04-16 Gelerbare farmaceutiske sammensætninger DK1073415T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9800329A BE1011899A6 (fr) 1998-04-30 1998-04-30 Compositions pharmaceutiques gelifiables utilisables.

Publications (1)

Publication Number Publication Date
DK1073415T3 true DK1073415T3 (da) 2006-03-06

Family

ID=3891230

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99923418T DK1073415T3 (da) 1998-04-30 1999-04-16 Gelerbare farmaceutiske sammensætninger

Country Status (26)

Country Link
US (3) US6464987B1 (bg)
EP (2) EP1073415B1 (bg)
JP (2) JP2002513748A (bg)
KR (1) KR100567975B1 (bg)
CN (1) CN1183901C (bg)
AT (2) ATE219659T1 (bg)
AU (2) AU738455B2 (bg)
BE (1) BE1011899A6 (bg)
BG (1) BG64723B1 (bg)
BR (1) BR9910066A (bg)
CA (1) CA2330500C (bg)
DE (2) DE69927963T2 (bg)
DK (1) DK1073415T3 (bg)
EA (1) EA002530B1 (bg)
ES (2) ES2178430T3 (bg)
HK (1) HK1033263A1 (bg)
HU (1) HU226556B1 (bg)
ID (1) ID26221A (bg)
IL (1) IL139113A0 (bg)
IS (1) IS2354B (bg)
NO (1) NO20005431L (bg)
NZ (1) NZ507707A (bg)
RS (1) RS50025B (bg)
TR (1) TR200003158T2 (bg)
WO (2) WO1999056726A1 (bg)
ZA (1) ZA200005915B (bg)

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1011899A6 (fr) * 1998-04-30 2000-02-01 Ucb Sa Compositions pharmaceutiques gelifiables utilisables.
US11026768B2 (en) 1998-10-08 2021-06-08 Align Technology, Inc. Dental appliance reinforcement
DE10024413A1 (de) * 2000-05-19 2001-12-06 Mika Pharma Gmbh Pharmazeutische und/oder kosmetische Zubereitung
DE10057769A1 (de) 2000-11-22 2002-05-23 Beiersdorf Ag Haarpflegeprodukte mit einem Gehalt an dispersen Flüssigkristallen, welche kubische Phasen darstellen
CN101785861B (zh) * 2001-10-19 2014-08-13 爱德士实验室公司 用于药理活性化合物的可控释放的可注射组合物
US6946137B2 (en) * 2001-10-19 2005-09-20 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
FR2837099B1 (fr) * 2002-03-12 2005-03-18 Ethypharm Sa Composition a proprietes gelifiantes destinee a la delivrance prolongee de substances bio-actives
EP1485066B1 (fr) * 2002-03-12 2016-09-21 Ethypharm Composition a proprietes gelifiantes destinee a la delivrance prolongee de substances bio-actives
US20040018237A1 (en) * 2002-05-31 2004-01-29 Perricone Nicholas V. Topical drug delivery using phosphatidylcholine
US8435942B2 (en) * 2002-05-31 2013-05-07 Transdermal Biotechnology, Inc. Methods for formulating stabilized insulin compositions
US20050031650A1 (en) * 2002-08-26 2005-02-10 Ethypharm Composition with gelling properties for the sustained delivery of bioactive substances
DE10255195A1 (de) * 2002-11-27 2004-06-09 Lipoid Gmbh Micellare wasserlösliche Konzentrate
JP5600233B2 (ja) * 2003-11-07 2014-10-01 カムルス エービー 脂質及びカチオン性ペプチドの組成物
US20070232695A1 (en) * 2004-01-28 2007-10-04 Collegium Pharmaceutical, Inc. Gelled Periodontal Anesthetic Preparation
US9492245B2 (en) 2004-02-27 2016-11-15 Align Technology, Inc. Method and system for providing dynamic orthodontic assessment and treatment profiles
GB0412530D0 (en) * 2004-06-04 2004-07-07 Camurus Ab Formulation
US8236292B2 (en) 2004-06-04 2012-08-07 Camurus Ab Liquid depot formulations
US7858115B2 (en) * 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
CN101048139A (zh) * 2004-10-28 2007-10-03 艾德克斯实验室公司 药物活性化合物的控释组合物
US20060115785A1 (en) 2004-11-30 2006-06-01 Chunhua Li Systems and methods for intra-oral drug delivery
US20060115782A1 (en) * 2004-11-30 2006-06-01 Chunhua Li Systems and methods for coating a dental appliance
US20070059350A1 (en) * 2004-12-13 2007-03-15 Kennedy John P Agents for controlling biological fluids and methods of use thereof
US20060127437A1 (en) * 2004-12-13 2006-06-15 Misty Anderson Kennedy Semisolid system and combination semisolid, multiparticulate system for sealing tissues and/or controlling biological fluids
US8920782B2 (en) * 2005-01-14 2014-12-30 Camurus Ab Topical bioadhesive formulations
US9649382B2 (en) * 2005-01-14 2017-05-16 Camurus Ab Topical bioadhesive formulations
CA2594711C (en) * 2005-01-14 2012-11-06 Camurus Ab Somatostatin analogue formulations
PL1848403T3 (pl) * 2005-01-14 2010-09-30 Camurus Ab Preparaty bioadhezyjne o działaniu miejscowym
US8871712B2 (en) * 2005-01-14 2014-10-28 Camurus Ab Somatostatin analogue formulations
CA2595385C (en) 2005-01-21 2011-01-25 Camurus Ab Pharmaceutical lipid compositions
WO2006131730A1 (en) * 2005-06-06 2006-12-14 Camurus Ab Glp-1 analogue formulations
SE531318C2 (sv) * 2007-02-22 2009-02-24 Tigran Technologies Ab Publ Injicerbar suspension innefattande titan-,titanlegerings- eller titanoxidpartiklar av mikrostruktur
US7878805B2 (en) 2007-05-25 2011-02-01 Align Technology, Inc. Tabbed dental appliance
GB0711656D0 (en) 2007-06-15 2007-07-25 Camurus Ab Formulations
GB0716385D0 (en) 2007-08-22 2007-10-03 Camurus Ab Formulations
WO2009047434A2 (fr) * 2007-09-12 2009-04-16 Galderma Research & Development Utilisation d'excipients en tant que conservateurs et composition pharmaceutique les comprenant
US8738394B2 (en) 2007-11-08 2014-05-27 Eric E. Kuo Clinical data file
FR2926996B1 (fr) * 2008-01-31 2013-06-21 Ethypharm Sa Composition pharmaceutique a proprietes gelifiantes contenant un derive de tyrosine
US8108189B2 (en) 2008-03-25 2012-01-31 Align Technologies, Inc. Reconstruction of non-visible part of tooth
US8092215B2 (en) 2008-05-23 2012-01-10 Align Technology, Inc. Smile designer
US9492243B2 (en) 2008-05-23 2016-11-15 Align Technology, Inc. Dental implant positioning
US8172569B2 (en) 2008-06-12 2012-05-08 Align Technology, Inc. Dental appliance
GB0815435D0 (en) 2008-08-22 2008-10-01 Camurus Ab Formulations
US20110229565A1 (en) 2008-09-17 2011-09-22 Karp Jeffrey M Drug Delivery Composition Comprising a Self-Assembled Gelator
US8152518B2 (en) 2008-10-08 2012-04-10 Align Technology, Inc. Dental positioning appliance having metallic portion
US8292617B2 (en) 2009-03-19 2012-10-23 Align Technology, Inc. Dental wire attachment
US8362013B2 (en) * 2009-04-30 2013-01-29 Abbvie Inc. Salt of ABT-263 and solid-state forms thereof
US20100297194A1 (en) * 2009-04-30 2010-11-25 Nathaniel Catron Formulation for oral administration of apoptosis promoter
US20100280031A1 (en) * 2009-04-30 2010-11-04 Paul David Lipid formulation of apoptosis promoter
US20100278921A1 (en) * 2009-04-30 2010-11-04 Fischer Cristina M Solid oral formulation of abt-263
US8728516B2 (en) * 2009-04-30 2014-05-20 Abbvie Inc. Stabilized lipid formulation of apoptosis promoter
TWI471321B (zh) * 2009-06-08 2015-02-01 Abbott Gmbh & Co Kg Bcl-2族群抑制劑之口服醫藥劑型
TWI532484B (zh) * 2009-06-08 2016-05-11 艾伯維有限公司 包含凋亡促進劑之固態分散劑
PL2387391T3 (pl) * 2009-07-24 2017-09-29 Mika Pharma Gesellschaft Für Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh Sposób otrzymywania ciekłej kompozycji stosowalnej w postaci piany na skórę oraz kompozycja do aplikowania miejscowego
US8765031B2 (en) 2009-08-13 2014-07-01 Align Technology, Inc. Method of forming a dental appliance
WO2011079127A1 (en) * 2009-12-22 2011-06-30 Abbott Laboratories Abt-263 capsule
AU2011223730A1 (en) * 2010-03-02 2012-10-18 Imagenetix, Inc. Compositions comprising myristic acid and uses thereof
US9241774B2 (en) 2010-04-30 2016-01-26 Align Technology, Inc. Patterned dental positioning appliance
US9211166B2 (en) 2010-04-30 2015-12-15 Align Technology, Inc. Individualized orthodontic treatment index
WO2012040623A2 (en) 2010-09-24 2012-03-29 The Brigham And Women's Hospital, Inc. Nanostructured gels capable of controlled release of encapsulated agents
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
EP2685962A1 (en) 2011-03-17 2014-01-22 Transdermal Biotechnology, Inc. Topical nitric oxide systems and methods of use thereof
US20140044779A1 (en) * 2011-04-18 2014-02-13 Lipidor Ab Liquid Carrier for Oral Delivery of a Pharmacologically Active Agent
US9403238B2 (en) 2011-09-21 2016-08-02 Align Technology, Inc. Laser cutting
US8716363B2 (en) * 2011-09-28 2014-05-06 Globus Medical, Inc. Biodegradable putty compositions and implant devices, methods, and kits relating to the same
EP2787975B1 (en) * 2011-12-05 2017-10-04 Camurus AB Robust controlled-release formulations
JP2015511117A (ja) * 2011-12-21 2015-04-16 ヒルズ・ペット・ニュートリシャン・インコーポレーテッド アスコルビル・エステルによる歯の病気の治療または減少
US9375300B2 (en) 2012-02-02 2016-06-28 Align Technology, Inc. Identifying forces on a tooth
US9220580B2 (en) 2012-03-01 2015-12-29 Align Technology, Inc. Determining a dental treatment difficulty
US9668974B2 (en) 2012-05-10 2017-06-06 Painreform Ltd. Depot formulations of a local anesthetic and methods for preparation thereof
US9414897B2 (en) 2012-05-22 2016-08-16 Align Technology, Inc. Adjustment of tooth position in a virtual dental model
AU2013265210B2 (en) 2012-05-25 2016-09-15 Camurus Ab Somatostatin receptor agonist formulations
EP2877155B1 (en) 2012-07-26 2020-10-28 Camurus AB Opioid formulations
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9750787B2 (en) 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9314422B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9393264B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9339457B2 (en) 2013-03-13 2016-05-17 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US20140271937A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9610141B2 (en) 2014-09-19 2017-04-04 Align Technology, Inc. Arch expanding appliance
US10449016B2 (en) 2014-09-19 2019-10-22 Align Technology, Inc. Arch adjustment appliance
US9744001B2 (en) 2014-11-13 2017-08-29 Align Technology, Inc. Dental appliance with cavity for an unerupted or erupting tooth
US10504386B2 (en) 2015-01-27 2019-12-10 Align Technology, Inc. Training method and system for oral-cavity-imaging-and-modeling equipment
US9610242B2 (en) * 2015-08-18 2017-04-04 Concept Labs, Inc. Water-gel emulsion compositions and methods
CN108289833B (zh) * 2015-10-08 2022-01-25 布里格姆及妇女医院股份有限公司 用于递送囊封剂的稳定的已组装纳米结构
US11554000B2 (en) 2015-11-12 2023-01-17 Align Technology, Inc. Dental attachment formation structure
US11931222B2 (en) 2015-11-12 2024-03-19 Align Technology, Inc. Dental attachment formation structures
US11103330B2 (en) 2015-12-09 2021-08-31 Align Technology, Inc. Dental attachment placement structure
US11596502B2 (en) 2015-12-09 2023-03-07 Align Technology, Inc. Dental attachment placement structure
EP3978022A1 (en) 2016-05-06 2022-04-06 The Brigham and Women's Hospital, Inc. Binary self assembled gels for controlled delivery of encapsulated agents to cartilage
EP3471653B1 (en) 2016-06-17 2021-12-22 Align Technology, Inc. Orthodontic appliance performance monitor
US10470847B2 (en) 2016-06-17 2019-11-12 Align Technology, Inc. Intraoral appliances with sensing
US10380212B2 (en) 2016-07-27 2019-08-13 Align Technology, Inc. Methods and apparatuses for forming a three-dimensional volumetric model of a subject's teeth
CN117257492A (zh) 2016-11-04 2023-12-22 阿莱恩技术有限公司 用于牙齿图像的方法和装置
EP3824843A1 (en) 2016-12-02 2021-05-26 Align Technology, Inc. Palatal expanders and methods of expanding a palate
AU2017366755B2 (en) 2016-12-02 2022-07-28 Align Technology, Inc. Methods and apparatuses for customizing rapid palatal expanders using digital models
US11376101B2 (en) 2016-12-02 2022-07-05 Align Technology, Inc. Force control, stop mechanism, regulating structure of removable arch adjustment appliance
WO2018102702A1 (en) 2016-12-02 2018-06-07 Align Technology, Inc. Dental appliance features for speech enhancement
US10548700B2 (en) 2016-12-16 2020-02-04 Align Technology, Inc. Dental appliance etch template
WO2018144991A1 (en) 2017-02-03 2018-08-09 The Brigham And Women's Hospital, Inc. Self-assembled gels formed with anti-retroviral drugs, prodrugs thereof, and pharmaceutical uses thereof
US10779718B2 (en) 2017-02-13 2020-09-22 Align Technology, Inc. Cheek retractor and mobile device holder
WO2018183358A1 (en) 2017-03-27 2018-10-04 Align Technology, Inc. Apparatuses and methods assisting in dental therapies
US10613515B2 (en) 2017-03-31 2020-04-07 Align Technology, Inc. Orthodontic appliances including at least partially un-erupted teeth and method of forming them
EP3621594A1 (en) 2017-05-08 2020-03-18 Alivio Therapeutics, Inc. Formulation of nanostructured gels for increased agent loading and adhesion
US11045283B2 (en) 2017-06-09 2021-06-29 Align Technology, Inc. Palatal expander with skeletal anchorage devices
CN110769777B (zh) 2017-06-16 2023-08-11 阿莱恩技术有限公司 牙齿类型和萌出状态的自动检测
US10639134B2 (en) 2017-06-26 2020-05-05 Align Technology, Inc. Biosensor performance indicator for intraoral appliances
US10885521B2 (en) 2017-07-17 2021-01-05 Align Technology, Inc. Method and apparatuses for interactive ordering of dental aligners
CN114903623A (zh) 2017-07-21 2022-08-16 阿莱恩技术有限公司 颚轮廓锚固
CN115462921A (zh) 2017-07-27 2022-12-13 阿莱恩技术有限公司 牙齿着色、透明度和上釉
EP4278957A3 (en) 2017-07-27 2024-01-24 Align Technology, Inc. System and methods for processing an orthodontic aligner by means of an optical coherence tomography
US20190046297A1 (en) * 2017-08-11 2019-02-14 Align Technology, Inc. Devices and systems for creation of attachments for use with dental appliances and changeable shaped attachments
US11116605B2 (en) 2017-08-15 2021-09-14 Align Technology, Inc. Buccal corridor assessment and computation
US11123156B2 (en) 2017-08-17 2021-09-21 Align Technology, Inc. Dental appliance compliance monitoring
US10813720B2 (en) 2017-10-05 2020-10-27 Align Technology, Inc. Interproximal reduction templates
CN114939001A (zh) 2017-10-27 2022-08-26 阿莱恩技术有限公司 替代咬合调整结构
EP3703608B1 (en) 2017-10-31 2023-08-30 Align Technology, Inc. Determination of a dental appliance having selective occlusal loading and controlled intercuspation
US11096763B2 (en) 2017-11-01 2021-08-24 Align Technology, Inc. Automatic treatment planning
WO2019100022A1 (en) 2017-11-17 2019-05-23 Align Technology, Inc. Orthodontic retainers
CN114948315B (zh) 2017-11-30 2024-08-27 阿莱恩技术有限公司 用于监测口腔矫治器的传感器
US11432908B2 (en) 2017-12-15 2022-09-06 Align Technology, Inc. Closed loop adaptive orthodontic treatment methods and apparatuses
US10980613B2 (en) 2017-12-29 2021-04-20 Align Technology, Inc. Augmented reality enhancements for dental practitioners
KR20200115580A (ko) 2018-01-26 2020-10-07 얼라인 테크널러지, 인크. 구강 내 진단 스캔 및 추적
US11937991B2 (en) 2018-03-27 2024-03-26 Align Technology, Inc. Dental attachment placement structure
CN108498376B (zh) * 2018-04-02 2020-11-13 榛硕(武汉)智能科技有限公司 一种甲基硅油乳液及其制备方法
AU2019251474B2 (en) 2018-04-11 2024-09-12 Align Technology, Inc. Releasable palatal expanders
WO2020076453A1 (en) 2018-10-11 2020-04-16 Alivio Therapeutics, Inc. Non-injectable hydrogel formulations for smart release
WO2020079706A1 (en) 2018-10-15 2020-04-23 Cipla Limited Pharmaceutical formulation
EP3848016A1 (en) * 2020-01-08 2021-07-14 3M Innovative Properties Company Oral care composition containing fatty acid components for treating caries
US11992483B2 (en) 2021-03-31 2024-05-28 Cali Biosciences Us, Llc Emulsions for local anesthetics
JP7092922B1 (ja) * 2021-06-11 2022-06-28 キユーピー株式会社 製剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5230899A (en) * 1985-08-07 1993-07-27 Smithkline Beecham Corporation Methods and compositions for making liposomes
US5262164A (en) * 1989-11-17 1993-11-16 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5230895A (en) * 1990-05-01 1993-07-27 Copley Pharmaceutical Inc. Sustained released delivery system for use in the periodontal pocket
US5567456A (en) * 1991-11-04 1996-10-22 Creative Products Inc. Of Rossville Food release compositions with organic fluidizing agents
CA2082561A1 (en) * 1991-11-12 1993-05-13 Francis J. Leng Antiperspirant materials and compositions
JP3190441B2 (ja) * 1992-07-20 2001-07-23 エーザイ株式会社 塩酸アゼラスチンを含有する安定な製剤
GB9224010D0 (en) * 1992-11-16 1993-01-06 Phares Pharma Holland Composition and method
PT711148E (pt) * 1993-07-28 2001-02-28 Pharmaderm Lab Ltd Vesicula lipidica multilamelar bifasica
DE19536244A1 (de) * 1994-09-30 1996-04-04 Juergen Dr Regenold Pharmazeutische Zusammensetzung zur lokalen Applikation
US5736152A (en) 1995-10-27 1998-04-07 Atrix Laboratories, Inc. Non-polymeric sustained release delivery system
BE1011899A6 (fr) * 1998-04-30 2000-02-01 Ucb Sa Compositions pharmaceutiques gelifiables utilisables.

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ATE219659T1 (de) 2002-07-15
CN1183901C (zh) 2005-01-12
KR20010043000A (ko) 2001-05-25
DE69901951T2 (de) 2002-11-28
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HU226556B1 (en) 2009-03-30
EP1073414B1 (fr) 2002-06-26
IS5669A (is) 2000-10-17
AU4030899A (en) 1999-11-23
BR9910066A (pt) 2000-12-26
NO20005431L (no) 2000-12-19
NO20005431D0 (no) 2000-10-27
ES2249891T3 (es) 2006-04-01
HUP0101580A3 (en) 2002-10-28
EA002530B1 (ru) 2002-06-27
IL139113A0 (en) 2001-11-25
ES2178430T3 (es) 2002-12-16
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CN1301147A (zh) 2001-06-27
DE69901951D1 (de) 2002-08-01
ID26221A (id) 2000-12-07
DE69927963T2 (de) 2006-06-29
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