DK1039802T3 - Transdermal terapeutisk anordning med capsicin og capsaicinanaloger - Google Patents

Transdermal terapeutisk anordning med capsicin og capsaicinanaloger

Info

Publication number
DK1039802T3
DK1039802T3 DK98962908T DK98962908T DK1039802T3 DK 1039802 T3 DK1039802 T3 DK 1039802T3 DK 98962908 T DK98962908 T DK 98962908T DK 98962908 T DK98962908 T DK 98962908T DK 1039802 T3 DK1039802 T3 DK 1039802T3
Authority
DK
Denmark
Prior art keywords
capsaicin
capsicin
therapeutic device
transdermal therapeutic
capsaicin analogues
Prior art date
Application number
DK98962908T
Other languages
Danish (da)
English (en)
Inventor
Wendye R Robbins
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK1039802T3 publication Critical patent/DK1039802T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
DK98962908T 1997-12-15 1998-12-08 Transdermal terapeutisk anordning med capsicin og capsaicinanaloger DK1039802T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/990,633 US6239180B1 (en) 1995-11-08 1997-12-15 Transdermal therapeutic device and method with capsaicin and capsaicin analogs
PCT/US1998/025794 WO1999030560A1 (fr) 1997-12-15 1998-12-08 Dispositif therapeutique transdermique et procede recourant a la capsaicine et a ses analogues

Publications (1)

Publication Number Publication Date
DK1039802T3 true DK1039802T3 (da) 2003-09-22

Family

ID=25536360

Family Applications (2)

Application Number Title Priority Date Filing Date
DK98962908T DK1039802T3 (da) 1997-12-15 1998-12-08 Transdermal terapeutisk anordning med capsicin og capsaicinanaloger
DK03005137T DK1316308T3 (da) 1997-12-15 1998-12-08 Transdermalt terapeutisk plaster med capsaicin og capsaicin-analoger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03005137T DK1316308T3 (da) 1997-12-15 1998-12-08 Transdermalt terapeutisk plaster med capsaicin og capsaicin-analoger

Country Status (11)

Country Link
US (2) US6239180B1 (fr)
EP (2) EP1316308B1 (fr)
AT (2) ATE240723T1 (fr)
CA (1) CA2314326C (fr)
CY (1) CY1107582T1 (fr)
DE (2) DE69836352T2 (fr)
DK (2) DK1039802T3 (fr)
ES (2) ES2272827T3 (fr)
HK (1) HK1030853A1 (fr)
PT (1) PT1039802E (fr)
WO (1) WO1999030560A1 (fr)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239180B1 (en) * 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
US6383511B1 (en) * 1999-10-25 2002-05-07 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
GB2355934B (en) * 1999-11-05 2003-11-05 Lohmann Gmbh & Co Kg Wound dressing
AUPQ622600A0 (en) * 2000-03-15 2000-04-06 Unisearch Limited Treatment and/or prevention of ocular pain
DE10056009A1 (de) * 2000-11-11 2002-05-16 Beiersdorf Ag Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung hyperämisierender Wirkstoffe
US8110217B2 (en) * 2001-08-13 2012-02-07 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
US7063860B2 (en) * 2001-08-13 2006-06-20 University Of Pittsburgh Application of lipid vehicles and use for drug delivery
US20030125347A1 (en) * 2001-11-02 2003-07-03 Elan Corporation Plc Pharmaceutical composition
EP1539124B1 (fr) * 2002-09-05 2018-07-18 Vanderbilt Royalty Sub L.P. Compositions et kits pour l'elimination de composes irritants de surfaces corporelles
EP1551402A4 (fr) * 2002-09-23 2009-05-27 Verion Inc Compositions pharmaceutiques n'induisant pas l'abus
US7687080B2 (en) * 2002-11-25 2010-03-30 Taraxos Inc. Treatment of neuropathy
US20040191338A1 (en) * 2002-12-18 2004-09-30 Algorx Administration of capsaicinoids
US20050020690A1 (en) 2002-12-18 2005-01-27 Algorx Infiltration of capsaicin into surgical sites and open wounds
US7235270B2 (en) 2003-03-10 2007-06-26 Mayeux Jerry V Pain balm
AU2004230915B2 (en) * 2003-04-08 2008-08-07 Algorx Pharmaceuticals, Inc. Preparation and purification of synthetic capsaicin
EP1610742B1 (fr) * 2003-04-10 2015-01-21 Neurogesx, Inc. Utilisation et compositions pour l'administration de la capsaïcine
PT1613297E (pt) * 2003-04-14 2007-08-23 Lohmann Therapie Syst Lts Emplastro terapêutico com matriz de polissiloxano compreendendo capsaicina
DE102004009904A1 (de) * 2004-02-26 2005-09-22 Grünenthal GmbH Kit aus einem gegebenenfalls wirkstoffhaltigen Pflaster und einem Hautirritationen verhindernden Mittel
CA2569155A1 (fr) * 2004-06-02 2005-12-15 Sri International Formulations contenant un casaicinoide, un anesthesiant local et/ou un agent antipruritique pour le traitement de la douleur
US7704522B2 (en) 2004-09-08 2010-04-27 Clyde Morgan Topical medicament
EA200701131A1 (ru) * 2004-11-24 2007-12-28 Алгоркс Фармасьютикалз, Инк. Гелеобразная препаративная форма капсаициноида и способы её применения
JP2006206471A (ja) * 2005-01-26 2006-08-10 Nitto Denko Corp テープ製剤
US20060204561A1 (en) * 2005-02-14 2006-09-14 Naweed Muhammad Device for delivery of TRPV1 agonists
WO2006099541A2 (fr) * 2005-03-15 2006-09-21 Richard Daniel Carliss Produit therapeutique pour soigner les blessures
EP1865933B1 (fr) * 2005-03-30 2015-11-04 Vanderbilt Royalty Sub L.P. Timbre transdermique a faible concentration de capsaicine et procedes de traitement des douleurs neuropathiques
WO2006107723A1 (fr) * 2005-04-01 2006-10-12 Neurogesx, Inc. Huiles de capsaicinoides et leurs methodes de conception et d'utilisation
US7282224B1 (en) 2006-06-09 2007-10-16 Guthy-Renker Corporation Pain relief composition
US7943666B2 (en) * 2006-07-24 2011-05-17 Trinity Laboratories, Inc. Esters of capsaicin for treating pain
US7645767B2 (en) * 2006-08-31 2010-01-12 Trinity Laboratories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
US20080107747A1 (en) * 2006-10-23 2008-05-08 Roederer Joy E Pain relief composition
EP2276420B1 (fr) 2008-04-04 2021-10-06 Journey1, Inc. Dispositif pour traiter un oeil ayant un épithélium défectueux
US8987328B2 (en) * 2008-10-30 2015-03-24 Trinity Laboratories, Inc. Esters of capsaicinoids as dietary supplements
NO2490635T3 (fr) 2009-10-23 2018-02-03
US8591025B1 (en) 2012-09-11 2013-11-26 Nexisvision, Inc. Eye covering and refractive correction methods for LASIK and other applications
US9498385B2 (en) 2009-10-23 2016-11-22 Nexisvision, Inc. Conformable therapeutic shield for vision and pain
WO2012061160A1 (fr) 2010-10-25 2012-05-10 Nexisvision, Inc. Procédés et appareils pour identifier des éléments de recouvrement des yeux pour la vue
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
JP2014514613A (ja) 2011-04-28 2014-06-19 ネクシスビジョン, インコーポレイテッド 涙流、快適性、および/または適用性が改善された、眼被覆物および屈折矯正法および装置
WO2014210186A2 (fr) 2013-06-26 2014-12-31 Nexisvision, Inc. Lentilles de contact pour correction réfractive
US9423632B2 (en) 2012-04-20 2016-08-23 Nexisvision, Inc. Contact lenses for refractive correction
US8889659B2 (en) 2011-09-09 2014-11-18 Api Genesis, Llc Pain relief compositions, manufacture and uses
US9465233B2 (en) 2012-04-20 2016-10-11 Nexisvision, Inc. Bimodular contact lenses
US9498461B2 (en) 2012-05-23 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
AU2013264896A1 (en) 2012-05-23 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9341864B2 (en) 2013-11-15 2016-05-17 Nexisvision, Inc. Contact lenses having a reinforcing scaffold
WO2015116559A1 (fr) 2014-01-29 2015-08-06 Nexisvision, Inc. Lentilles de contact bimodules multifocales
WO2015160941A1 (fr) 2014-04-15 2015-10-22 Vizuri Health Sciences Llc Compositions topiques pour le soulagement de la douleur, leur fabrication et leur utilisation
SG11201706952VA (en) 2014-09-26 2017-10-30 Cellix Bio Private Ltd Compositions and methods for the treatment of epilepsy and neurological disorders
JP6698643B2 (ja) 2014-09-29 2020-05-27 セリックス バイオ プライヴェート リミテッドCellix Bio Private Limited 多発性硬化症の治療のための組成物及び方法
CN107108535B (zh) 2014-10-27 2020-04-28 塞尔利克斯生物私人有限公司 用于治疗多发性硬化的富马酸单甲酯与哌嗪或乙二胺的三组分盐
WO2016067297A1 (fr) 2014-10-27 2016-05-06 Cellix Bio Private Limited Sels de l'acide valproïque associés à des dérivés aminés de la pipérazine, l'éthylènediamine, la lysine et/ou l'acide eicosapentaénoïque (epa) pour le traitement de l'épilepsie
WO2016088132A1 (fr) 2014-12-01 2016-06-09 Cellix Bio Private Limited Compositions et méthodes pour le traitement de la sclérose en plaques
CA2976187A1 (fr) 2015-02-09 2016-08-18 Cellix Bio Private Limited Sels de benzydamine et compositions connexes utiles pour le traitement de la mucosite
WO2017020125A1 (fr) 2015-07-31 2017-02-09 Delivra Inc. Préparations transdermiques pour administration de capsaïcinoïdes
NZ750126A (en) 2016-08-11 2022-07-01 Cellix Bio Private Ltd Compositions and methods for the treatment of irritable bowel syndrome
CA3039125A1 (fr) 2016-10-04 2018-04-12 Cellix Bio Private Limited Compositions et methodes pour le traitement de la xerostomie
WO2018115984A1 (fr) 2016-12-19 2018-06-28 Cellix Bio Private Limited Compositions et méthodes pour le traitement d'une inflammation
BR112020001748A2 (pt) 2017-07-27 2020-07-21 Allergan, Inc. agonistas de receptor de prostaciclina para redução de gordura corporal
RU2761436C1 (ru) 2017-11-17 2021-12-08 Целликс Био Прайвет Лимитед Композиции и способы лечения нарушений со стороны органа зрения
AU2018369853B2 (en) 2017-11-17 2022-07-14 Cellix Bio Private Limited Compounds, compositions and methods for treatment of eye disorders and skin diseases
JP2023517745A (ja) 2020-03-17 2023-04-26 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 初期非応答者を治療するためのカプサイシンパッチの繰り返しの局所適用
US20230310351A1 (en) 2020-04-03 2023-10-05 Gruenenthal Gmbh Regimen for repeated topical application of capsaicin patch
RU2755206C1 (ru) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Средство пролонгированного анальгетического действия и лекарственный препарат на его основе
US11234947B2 (en) * 2020-06-30 2022-02-01 Imperial College Innovations Limited Treatment of peripheral neuropathy induced by cancer chemotherapy

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486450B1 (en) 1980-07-14 1998-07-28 Joel E Bernstein Method of treating psoriatic skin and composition
US4313958A (en) 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
US4424205A (en) 1982-03-18 1984-01-03 The Procter & Gamble Company Hydroxyphenylacetamides having analgesic and anti-irritant activity
US4536404A (en) 1983-06-16 1985-08-20 Dermatological Enterprises, Ltd. Method and composition for treating post-herpetic neuralgia
US4532139A (en) 1983-07-14 1985-07-30 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4544669A (en) 1983-07-14 1985-10-01 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4544668A (en) 1983-07-14 1985-10-01 The Procter & Gamble Company Compounds and compositions useful for producing analgesia
US4592912A (en) 1983-10-31 1986-06-03 Harriet Nickolaus Ache and pain relieving and preventing composition
US4681897A (en) 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4898887A (en) * 1984-12-20 1990-02-06 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity
US4971800A (en) 1988-07-08 1990-11-20 The Regents Of The University Of California Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents
US4939149A (en) 1988-10-24 1990-07-03 The United States Of America As Represented By The Department Of Health And Human Services Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization
US4997853A (en) 1988-12-02 1991-03-05 Galenpharma, Inc. Method and compositions utilizing capsaicin as an external analgesic
CA1338779C (fr) 1989-03-17 1996-12-10 Harry Hind Methode pour traiter les douleurs associees au zona et les nevralgies post-zona grace a l'application topique d'anesthesiques locaux
US5411738A (en) 1989-03-17 1995-05-02 Hind Health Care, Inc. Method for treating nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia) by topical application of lidocaine
WO1990014083A1 (fr) 1989-05-15 1990-11-29 Afferon Corporation Composition et procede de desensibilisation neurale
US5063060A (en) 1989-12-19 1991-11-05 Cisco Limited Partnership Compositions and method for treating painful, inflammatory or allergic disorders
JP2748199B2 (ja) * 1991-08-27 1998-05-06 泰一郎 岩倉 気管支喘息発作の予防と治療貼付剤
US5260313A (en) 1992-03-12 1993-11-09 National Pain Institute, Inc. Diagnosis and treatment of various neuralgias
US5431914A (en) 1992-04-17 1995-07-11 Adekunle; Michael Method of treating an internal condition by external application of capsaicin without the need for systemic absorption
JP3414423B2 (ja) * 1992-11-27 2003-06-09 積水化学工業株式会社 眠気防止用外用剤及び貼付剤
US5665360A (en) 1993-05-14 1997-09-09 Mann; Richard H. Method of treating peripheral neuropathies of the feet and legs
US5910512A (en) 1994-04-18 1999-06-08 Healthline Laboratories, Inc. Topical analgesic using water soluble capsaicin
DE4414502A1 (de) * 1994-04-26 1995-11-02 Edda Scholten Salbe zur äußerlichen Anwendung bei Schmerzen
US5665378A (en) 1994-09-30 1997-09-09 Davis; Roosevelt Transdermal therapeutic formulation
US5762963A (en) 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US5788982A (en) 1995-06-16 1998-08-04 Nadoolman; Wolffe Method and composition for treating oral pain using capsaicin
US6239180B1 (en) * 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
US5854291A (en) 1996-04-23 1998-12-29 Medical Merchandising, Inc. Pain reliever and method of use
US5856361A (en) 1996-04-23 1999-01-05 Medical Merchandising, Inc. Pain reliever and method of use
US5869533A (en) 1996-04-23 1999-02-09 Holt; Stephen D. Non-irritating capsaicin formulations and applicators therefor
EP1201241B8 (fr) 1997-03-13 2010-10-27 James N. Campbell Compositions contenant de la capsaicine ou des analogues de capsaicine et un anesthésique
AU2466799A (en) 1998-01-22 1999-08-09 Regents Of The University Of California, The Nucleic acid sequences encoding capsaicin receptors
KR20060085258A (ko) 1998-02-24 2006-07-26 웨이크 포리스트 유니버시티 만성 통증 및 여성에 특유한 통증을 비롯한 통증의 치료방법

Also Published As

Publication number Publication date
ES2196640T3 (es) 2003-12-16
DE69814917T2 (de) 2004-02-12
DE69836352T2 (de) 2007-05-24
EP1316308A1 (fr) 2003-06-04
US6239180B1 (en) 2001-05-29
DE69814917D1 (de) 2003-06-26
EP1316308B1 (fr) 2006-11-02
EP1039802A1 (fr) 2000-10-04
PT1039802E (pt) 2003-10-31
ES2272827T3 (es) 2007-05-01
EP1039802B1 (fr) 2003-05-21
CY1107582T1 (el) 2013-03-13
ATE240723T1 (de) 2003-06-15
DE69836352D1 (de) 2006-12-14
ATE344023T1 (de) 2006-11-15
CA2314326C (fr) 2008-11-18
DK1316308T3 (da) 2007-03-05
CA2314326A1 (fr) 1999-06-24
WO1999030560A1 (fr) 1999-06-24
HK1030853A1 (en) 2001-05-25
US20010002406A1 (en) 2001-05-31
EP1039802A4 (fr) 2002-01-23

Similar Documents

Publication Publication Date Title
DK1039802T3 (da) Transdermal terapeutisk anordning med capsicin og capsaicinanaloger
DK1201241T3 (da) Sammensætninger indeholdende capsaicin eller capsaicinanaloge og et bedøvelsesmiddel
GEP20002146B (en) Therapeutic Peptide Derivatives
DK0480934T3 (da) Lægemiddel, der indeholder ephedrin og koffein til behandling af overvægt
NZ504026A (en) Methods for treating hypercoagulable states or acquired protein C deficiency using human-activated protein C
IS4083A (is) Samsetning lyfjaefna, aðferð til framleiðslu hennar, og notkunar sem lyfja
ATE140388T1 (de) Zusammensetzungen enthaltend omega conotoxin peptide derivate und deren verwendung zur behandlung von ischämie-artigen neuronalen schädigungen
DE69213814D1 (de) Melatoninderivate zur Behandlung von Schlafstörungen und zur Pre-Anästhesie
ES2166783T3 (es) Factor viii activado utilizado como agente terapeutico y metodo para el tratamiento de la deficiencia de factor viii.
DE69625682D1 (de) Verfahren zur behandlung von entzündungen und zusammensetzungen dafür
NO995944D0 (no) Anti-arrytmisk blanding og fremgangsmåter for behandling
ATE200617T1 (de) Pharmazeutische zusammensetzungen zur transdermalen verabreichung von melatonin und/oder seine analoge
ATE126061T1 (de) Verwendung von lithium zur behandlung oder prophylaxe von molluscum contagiusum.
MX9700967A (es) Uso terapeutico de acetazolamida para el tratamiento de edema cerebral.
CY1108368T1 (el) Διαδερμικη συσκευη φελοδιπινης και μεθοδοι
EA200600757A1 (ru) Тетрапептид, регулирующий уровень глюкозы в крови при сахарном диабете
NO960866L (no) Fremgangsmåte til behandling av leversykdom og lignende indikasjoner med vasodilaterende midler
RU95122262A (ru) Способ лечения повреждений периферических нервов при травмах конечностей
UA28769A (uk) Спосіб лікування променевих ушкоджень шкіри
UA32384A (uk) Спосіб лікування пародонтиту