DK1030842T3 - Metalloproteinaseinhibitorer - Google Patents

Metalloproteinaseinhibitorer

Info

Publication number
DK1030842T3
DK1030842T3 DK97912351T DK97912351T DK1030842T3 DK 1030842 T3 DK1030842 T3 DK 1030842T3 DK 97912351 T DK97912351 T DK 97912351T DK 97912351 T DK97912351 T DK 97912351T DK 1030842 T3 DK1030842 T3 DK 1030842T3
Authority
DK
Denmark
Prior art keywords
methoxysuccinamide
pyridin
isobutyl
propyl
hydroxy
Prior art date
Application number
DK97912351T
Other languages
Danish (da)
English (en)
Inventor
Raymond Paul Beckett
Mark Whittaker
Andrew Miller
Fionna Mitchell Martin
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Application granted granted Critical
Publication of DK1030842T3 publication Critical patent/DK1030842T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK97912351T 1997-11-13 1997-11-13 Metalloproteinaseinhibitorer DK1030842T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1997/003132 WO1999025693A1 (en) 1997-11-13 1997-11-13 Metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
DK1030842T3 true DK1030842T3 (da) 2003-07-28

Family

ID=10807699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97912351T DK1030842T3 (da) 1997-11-13 1997-11-13 Metalloproteinaseinhibitorer

Country Status (21)

Country Link
EP (1) EP1030842B1 (no)
JP (1) JP2001523666A (no)
KR (1) KR100485479B1 (no)
AT (1) ATE236126T1 (no)
AU (1) AU740420B2 (no)
BR (1) BR9714934A (no)
CA (1) CA2310593C (no)
DE (1) DE69720554T2 (no)
DK (1) DK1030842T3 (no)
ES (1) ES2195122T3 (no)
GB (1) GB2333524A (no)
HU (1) HUP0002811A3 (no)
IL (1) IL135210A0 (no)
NO (1) NO315702B1 (no)
NZ (1) NZ503642A (no)
PL (1) PL189542B1 (no)
PT (1) PT1030842E (no)
RU (1) RU2198164C2 (no)
TR (1) TR200001353T2 (no)
TW (1) TW474919B (no)
WO (1) WO1999025693A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ290145B6 (cs) * 1994-01-20 2002-06-12 British Biotech Pharmaceuticals Limited Inhibitory metaloproteinázy
AU2986295A (en) * 1995-07-19 1997-02-18 British Biotech Pharmaceuticals Limited N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors

Also Published As

Publication number Publication date
AU4958497A (en) 1999-06-07
DE69720554T2 (de) 2004-01-08
EP1030842A1 (en) 2000-08-30
HUP0002811A2 (hu) 2001-01-29
PL189542B1 (pl) 2005-08-31
AU740420B2 (en) 2001-11-01
DE69720554D1 (de) 2003-05-08
RU2198164C2 (ru) 2003-02-10
KR100485479B1 (ko) 2005-04-27
BR9714934A (pt) 2000-10-03
NO20002480D0 (no) 2000-05-12
NO20002480L (no) 2000-05-12
GB9816317D0 (en) 1998-09-23
HUP0002811A3 (en) 2002-11-28
PL340494A1 (en) 2001-02-12
NO315702B1 (no) 2003-10-13
NZ503642A (en) 2001-10-26
ATE236126T1 (de) 2003-04-15
PT1030842E (pt) 2003-07-31
IL135210A0 (en) 2001-05-20
KR20010031879A (ko) 2001-04-16
CA2310593A1 (en) 1999-05-27
TW474919B (en) 2002-02-01
CA2310593C (en) 2007-05-08
GB2333524A (en) 1999-07-28
TR200001353T2 (tr) 2000-10-23
WO1999025693A1 (en) 1999-05-27
ES2195122T3 (es) 2003-12-01
JP2001523666A (ja) 2001-11-27
EP1030842B1 (en) 2003-04-02

Similar Documents

Publication Publication Date Title
ITMI921601A1 (it) Uso di nor- e omo-derivati di acidi biliari come promotori di assorbimento di farmaci.
TR200101969T2 (tr) Enflamasyon tedavisi için sübstitüe edilmiş benzopiran analogları.
AR012172A2 (es) Composiciones farmaceuticas que comprenden analogos de lactacistina y uso de los mismos para la fabricacion de un medicamento
DE69824622D1 (de) Verwendung von vitamin d derivaten zur verstärkung der wirkung von zytotoxischen stoffen
DE69015736D1 (de) 7-Keto- und 7-Hydroxy-androsta-3,5-dien-3-carbonsäure Derivate.
ATE163923T1 (de) 25-carbonsäure-derivate in der vitamin d-reihe, diese derivate enthaltende pharmazeutische präparate sowie deren verwendung zur herstellung von arzneimitteln
DE3778770D1 (de) Neue diphenylpropylamin-derivate, ihre herstellung sowie ihre pharmazeutische verwendung.
RU94037246A (ru) Применение 2-фенил-3-ароилбензотиофенов для ингибирования разрушения хряща
DE68909548T2 (de) Organische Hydrazin-Verbindungen für pharmazeutische Anwendung.
DK1030842T3 (da) Metalloproteinaseinhibitorer
EA200400096A1 (ru) Применение корриноидов при кожных заболеваниях
AU5516590A (en) Dehydrocholecalciferol derivatives
ITPD920145A1 (it) Uso terapeutico della fosforil-l-serina-n-acil-sfingosina
AU640647B2 (en) 3-butenamide derivatives
DE69414396T2 (de) Acylphenylglycin-derivat und dieses als aktivbestandteil enthaltendes vorbeugungs -und heilmittel gegen durch erhöhte collagenaseaktivität verursachte krankheiten
FI860074A (fi) Oktahydroindolizinfoereningar anvaendbara som smaertstillande medel.
BR9906975A (pt) Composto, uso do mesmo, composição farmacêutica, e, processo para estimular a liberação do hormÈnio do crescimento pela pituitária de um mamìfero
MX9706283A (es) Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo.
ES2073850T3 (es) Aductos con etanol de 3-hidroxicromanos sustituidos con sulfonilo en posicion 6 y su utilizacion como agentes para inhalacion en enfermedades.
AR019664A1 (es) Composicion para el tratamiento de enfermedades del cartilago
MX9203068A (es) Compuestos activirales oralmente activos.
DE69201863D1 (de) Acylaminoalkylidenhydroxybisphosphonsäure brauchbar in der Therapie von osteoartikularen Krankheiten.
DE69528984D1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
CO4780024A1 (es) Nuevos derivados del acido hidroxamico utiles para el tratamiento de enfermedades relacionadas con la degradacion del tejido conectivo
SU1556054A1 (ru) 4-(1-карбоксипентокси)-коричная кислота, обладающая гипотензивной активностью