PT1030842E - Inibidores da metaloproteinase - Google Patents

Inibidores da metaloproteinase

Info

Publication number
PT1030842E
PT1030842E PT97912351T PT97912351T PT1030842E PT 1030842 E PT1030842 E PT 1030842E PT 97912351 T PT97912351 T PT 97912351T PT 97912351 T PT97912351 T PT 97912351T PT 1030842 E PT1030842 E PT 1030842E
Authority
PT
Portugal
Prior art keywords
methoxysuccinamide
pyridin
isobutyl
propyl
hydroxy
Prior art date
Application number
PT97912351T
Other languages
English (en)
Inventor
Raymond Paul Beckett
Fionna Mitchell Martin
Mark Whittaker
Andrew Miller
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Publication of PT1030842E publication Critical patent/PT1030842E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT97912351T 1997-11-13 1997-11-13 Inibidores da metaloproteinase PT1030842E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1997/003132 WO1999025693A1 (en) 1997-11-13 1997-11-13 Metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
PT1030842E true PT1030842E (pt) 2003-07-31

Family

ID=10807699

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97912351T PT1030842E (pt) 1997-11-13 1997-11-13 Inibidores da metaloproteinase

Country Status (21)

Country Link
EP (1) EP1030842B1 (pt)
JP (1) JP2001523666A (pt)
KR (1) KR100485479B1 (pt)
AT (1) ATE236126T1 (pt)
AU (1) AU740420B2 (pt)
BR (1) BR9714934A (pt)
CA (1) CA2310593C (pt)
DE (1) DE69720554T2 (pt)
DK (1) DK1030842T3 (pt)
ES (1) ES2195122T3 (pt)
GB (1) GB2333524A (pt)
HU (1) HUP0002811A3 (pt)
IL (1) IL135210A0 (pt)
NO (1) NO315702B1 (pt)
NZ (1) NZ503642A (pt)
PL (1) PL189542B1 (pt)
PT (1) PT1030842E (pt)
RU (1) RU2198164C2 (pt)
TR (1) TR200001353T2 (pt)
TW (1) TW474919B (pt)
WO (1) WO1999025693A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0822186B1 (en) * 1994-01-20 2000-03-15 British Biotech Pharmaceuticals Limited L-tert-leucine-2-pyridylamide
AU2986295A (en) * 1995-07-19 1997-02-18 British Biotech Pharmaceuticals Limited N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors

Also Published As

Publication number Publication date
KR20010031879A (ko) 2001-04-16
HUP0002811A2 (hu) 2001-01-29
DK1030842T3 (da) 2003-07-28
AU740420B2 (en) 2001-11-01
DE69720554D1 (de) 2003-05-08
ATE236126T1 (de) 2003-04-15
KR100485479B1 (ko) 2005-04-27
IL135210A0 (en) 2001-05-20
JP2001523666A (ja) 2001-11-27
GB9816317D0 (en) 1998-09-23
DE69720554T2 (de) 2004-01-08
ES2195122T3 (es) 2003-12-01
NO20002480D0 (no) 2000-05-12
PL189542B1 (pl) 2005-08-31
AU4958497A (en) 1999-06-07
TW474919B (en) 2002-02-01
EP1030842B1 (en) 2003-04-02
WO1999025693A1 (en) 1999-05-27
TR200001353T2 (tr) 2000-10-23
HUP0002811A3 (en) 2002-11-28
NO20002480L (no) 2000-05-12
GB2333524A (en) 1999-07-28
RU2198164C2 (ru) 2003-02-10
CA2310593C (en) 2007-05-08
NO315702B1 (no) 2003-10-13
EP1030842A1 (en) 2000-08-30
BR9714934A (pt) 2000-10-03
PL340494A1 (en) 2001-02-12
CA2310593A1 (en) 1999-05-27
NZ503642A (en) 2001-10-26

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