DK1019048T3 - Anvendelse af en angiotensin II-reseptorantagonist til fremstilling af lægemidler til forøgelse af overlevelsesfrekvensen af nyretransplanterede patienter - Google Patents
Anvendelse af en angiotensin II-reseptorantagonist til fremstilling af lægemidler til forøgelse af overlevelsesfrekvensen af nyretransplanterede patienterInfo
- Publication number
- DK1019048T3 DK1019048T3 DK98946713T DK98946713T DK1019048T3 DK 1019048 T3 DK1019048 T3 DK 1019048T3 DK 98946713 T DK98946713 T DK 98946713T DK 98946713 T DK98946713 T DK 98946713T DK 1019048 T3 DK1019048 T3 DK 1019048T3
- Authority
- DK
- Denmark
- Prior art keywords
- transplant patients
- preparation
- increase
- receptor antagonist
- survival rate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97RM000586A IT1295405B1 (it) | 1997-09-30 | 1997-09-30 | Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di |
PCT/IT1998/000259 WO1999016437A1 (fr) | 1997-09-30 | 1998-09-30 | Utilisation d'un antagoniste du recepteur de l'angiotensine ii pour la preparation de medicaments servant a accroitre le taux de survie des patients ayant subi une transplantation renale |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1019048T3 true DK1019048T3 (da) | 2004-05-03 |
Family
ID=11405271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98946713T DK1019048T3 (da) | 1997-09-30 | 1998-09-30 | Anvendelse af en angiotensin II-reseptorantagonist til fremstilling af lægemidler til forøgelse af overlevelsesfrekvensen af nyretransplanterede patienter |
Country Status (12)
Country | Link |
---|---|
US (1) | US6576652B2 (fr) |
EP (1) | EP1019048B1 (fr) |
JP (1) | JP2001517698A (fr) |
AT (1) | ATE258051T1 (fr) |
AU (1) | AU754852B2 (fr) |
CA (1) | CA2303217C (fr) |
DE (1) | DE69821252T2 (fr) |
DK (1) | DK1019048T3 (fr) |
ES (1) | ES2213296T3 (fr) |
IT (1) | IT1295405B1 (fr) |
PT (1) | PT1019048E (fr) |
WO (1) | WO1999016437A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
BR0102252B1 (pt) | 2001-04-10 | 2013-10-22 | Sistema de liberação controlada para antagonista do receptor AT1 da angiotensina II, composição farmacêutica e seu uso | |
DE60304175T2 (de) | 2002-04-29 | 2007-03-15 | Teva Pharmaceutical Industries Ltd. | Verfahren zur herstellung von losartan und losartan-kaliumsalz |
WO2005097109A1 (fr) * | 2004-04-01 | 2005-10-20 | Daniel Batlle | Methodes pour obtenir un niveau d'expression d'ace2 protecteur |
WO2005110386A2 (fr) * | 2004-04-13 | 2005-11-24 | Wisconsin Alumni Research Foundation | Methode permettant de reduire l'inflammation lors d'une greffe de rein a l'aide d'agents bloquant les recepteurs de l'angiotensine |
US7531560B2 (en) * | 2004-11-10 | 2009-05-12 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
ES2753874T3 (es) * | 2009-04-28 | 2020-04-14 | Daiichi Sankyo Co Ltd | Cristales de solvato novedosos |
AU2013345894B2 (en) * | 2012-11-14 | 2017-05-25 | Teijin Limited | Pyridine derivative |
WO2018002673A1 (fr) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Nouvelles formulations d'antagonistes du récepteur de l'angiotensine ii |
AU2019246406A1 (en) * | 2018-03-29 | 2020-10-15 | Bruno Reichart | Compositions for prolonging the survival after orthopic and heteropic xenogeneic heart, kidney, lung or liver transplantations |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH528514A (de) | 1969-05-22 | 1972-09-30 | Bayer Ag | Verfahren zur Herstellung von Acylimidazolen |
JPS54148788A (en) | 1978-05-15 | 1979-11-21 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation |
JPS55313A (en) | 1978-06-13 | 1980-01-05 | Kissei Pharmaceut Co Ltd | Imidazole derivative |
DK531479A (da) | 1979-01-19 | 1980-07-20 | Pfizer | Fremgangsmaade til fremstilling af imidazolderivater og salte deraf |
JPS5671073A (en) | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | Imidazole derivative |
JPS5671074A (en) | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
DE3106150A1 (de) | 1981-02-13 | 1982-09-16 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "verfahren zur herstellung von imidazolessigsaeurederivaten" |
JPS58157768A (ja) | 1982-03-16 | 1983-09-19 | Takeda Chem Ind Ltd | 4−クロロ−2−フエニルイミダゾ−ル−5−酢酸誘導体 |
PT78388B (en) | 1983-04-12 | 1986-09-15 | Smithkline Beckman Corp | Dopamine-beta-hydroxylase inhibitors |
FI833794A0 (fi) | 1983-10-18 | 1983-10-18 | Farmos Oy | Substituerade 2-merkapto-imidazoler |
US5138069A (en) | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
US5064825A (en) * | 1989-06-01 | 1991-11-12 | Merck & Co., Inc. | Angiotensin ii antagonists |
EP0505098A1 (fr) * | 1991-03-19 | 1992-09-23 | Merck & Co. Inc. | Dérivés d'imidazole ayant des groupes fonctionnels acides comme angiotensin II antagonistes |
US5492904A (en) * | 1991-05-15 | 1996-02-20 | E. I. Du Pont De Nemours And Company | Composition of angiotensin-II receptor antagonists and calcium channel blockers |
US5130439A (en) | 1991-11-18 | 1992-07-14 | Lo Young S | Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists |
DE69233208T2 (de) | 1991-11-18 | 2004-07-08 | E.I. Du Pont De Nemours And Co., Wilmington | Tetrazolylphenylborsäureintermediate zur synthese von aii rezeptor antagonisten |
US5219856A (en) * | 1992-04-06 | 1993-06-15 | E. I. Du Pont De Nemours And Company | Angiotensin-II receptor blocking, heterocycle substituted imidazoles |
US5310929A (en) * | 1992-08-06 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists |
US5395844A (en) * | 1993-06-10 | 1995-03-07 | The Du Pont Merck Pharmaceutical Company | Imidazole 5-position substituted angiotensin II antagonists |
BR9611007A (pt) * | 1995-10-06 | 1999-07-13 | Novartis Ag | Antagonistas do receptor at1 para prevenir e tratar a deficiência renal pós-isquêmica e para a proteção de rins isquêmicos |
CA2238975A1 (fr) * | 1995-12-12 | 1997-06-19 | Merck & Co., Inc. | Nouvelle utilisation du losartan |
-
1997
- 1997-09-30 IT IT97RM000586A patent/IT1295405B1/it active IP Right Grant
-
1998
- 1998-09-30 DK DK98946713T patent/DK1019048T3/da active
- 1998-09-30 WO PCT/IT1998/000259 patent/WO1999016437A1/fr active IP Right Grant
- 1998-09-30 JP JP2000513573A patent/JP2001517698A/ja active Pending
- 1998-09-30 PT PT98946713T patent/PT1019048E/pt unknown
- 1998-09-30 DE DE1998621252 patent/DE69821252T2/de not_active Expired - Lifetime
- 1998-09-30 CA CA002303217A patent/CA2303217C/fr not_active Expired - Fee Related
- 1998-09-30 AU AU93666/98A patent/AU754852B2/en not_active Ceased
- 1998-09-30 EP EP98946713A patent/EP1019048B1/fr not_active Expired - Lifetime
- 1998-09-30 ES ES98946713T patent/ES2213296T3/es not_active Expired - Lifetime
- 1998-09-30 AT AT98946713T patent/ATE258051T1/de active
-
2002
- 2002-02-19 US US10/076,396 patent/US6576652B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020115702A1 (en) | 2002-08-22 |
PT1019048E (pt) | 2004-05-31 |
AU754852B2 (en) | 2002-11-28 |
DE69821252T2 (de) | 2004-11-18 |
CA2303217A1 (fr) | 1999-04-08 |
EP1019048A1 (fr) | 2000-07-19 |
DE69821252D1 (de) | 2004-02-26 |
JP2001517698A (ja) | 2001-10-09 |
ITRM970586A1 (it) | 1999-03-30 |
ATE258051T1 (de) | 2004-02-15 |
WO1999016437A1 (fr) | 1999-04-08 |
IT1295405B1 (it) | 1999-05-12 |
CA2303217C (fr) | 2005-08-09 |
EP1019048B1 (fr) | 2004-01-21 |
AU9366698A (en) | 1999-04-23 |
ES2213296T3 (es) | 2004-08-16 |
US6576652B2 (en) | 2003-06-10 |
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