DK1011329T3 - 7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler - Google Patents

7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler

Info

Publication number
DK1011329T3
DK1011329T3 DK98908734T DK98908734T DK1011329T3 DK 1011329 T3 DK1011329 T3 DK 1011329T3 DK 98908734 T DK98908734 T DK 98908734T DK 98908734 T DK98908734 T DK 98908734T DK 1011329 T3 DK1011329 T3 DK 1011329T3
Authority
DK
Denmark
Prior art keywords
methylthiooxomethyl
methylthiodioxomethyl
paclitaxels
present
invention concerns
Prior art date
Application number
DK98908734T
Other languages
Danish (da)
English (en)
Inventor
Jerzy Golik
Dolatrai M Vyas
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK1011329T3 publication Critical patent/DK1011329T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98908734T 1997-02-28 1998-02-24 7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler DK1011329T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3948097P 1997-02-28 1997-02-28
PCT/US1998/003741 WO1998037765A1 (en) 1997-02-28 1998-02-24 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels

Publications (1)

Publication Number Publication Date
DK1011329T3 true DK1011329T3 (da) 2003-12-22

Family

ID=21905699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98908734T DK1011329T3 (da) 1997-02-28 1998-02-24 7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler

Country Status (11)

Country Link
US (1) US5902822A (de)
EP (1) EP1011329B1 (de)
JP (1) JP2001513778A (de)
AT (1) ATE250340T1 (de)
AU (1) AU724591B2 (de)
CA (1) CA2282264A1 (de)
DE (1) DE69818492T2 (de)
DK (1) DK1011329T3 (de)
ES (1) ES2207817T3 (de)
PT (1) PT1011329E (de)
WO (1) WO1998037765A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046904A1 (en) * 1998-03-12 1999-09-16 John Griffits Improved realtime internet functions by use of a hybrid pstn and ip protocol means
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
WO2001098286A1 (en) 2000-06-22 2001-12-27 Nitromed, Inc. Nitrosated and nitrosylated taxanes, compositions and methods of use
PL217731B1 (pl) 2006-06-01 2014-08-29 Tomasz Byrski Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi
TN2015000543A1 (en) 2013-06-11 2017-04-06 Bayer Pharma AG Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
AU663732B2 (en) * 1991-09-23 1995-10-19 Bristol-Myers Squibb Company 10-desacetoxytaxol derivatives
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
EP0639186B1 (de) * 1992-04-17 1999-06-23 Abbott Laboratories Taxol-derivate
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
FR2697019B1 (fr) * 1992-10-15 1994-11-25 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.
CA2109861C (en) * 1992-12-04 1999-03-16 Shu-Hui Chen 6,7-modified paclitaxels
ES2252362T3 (es) * 1992-12-23 2006-05-16 Bristol-Myers Squibb Company Nuevos taxanos portadores de cadena lateral y productos intermedios de los mismos,.
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
CA2111527C (en) * 1992-12-24 2000-07-18 Jerzy Golik Phosphonooxymethyl ethers of taxane derivatives
AU689770B2 (en) * 1993-03-05 1998-04-09 Florida State University Process for the preparation of 9-desoxotaxanes
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
CA2192373A1 (en) * 1994-06-09 1995-12-14 Hirofumi Terasawa Deacetoxytaxol derivative
NZ288802A (en) * 1994-06-28 1998-05-27 Upjohn Co Ether taxol derivatives, preparation and pharmaceutical compositions thereof
CA2195844C (en) * 1994-07-26 2001-10-09 Ezio Bombardelli Semi-synthetic taxanes with anti-tumoural activity
US6201140B1 (en) * 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives

Also Published As

Publication number Publication date
DE69818492D1 (en) 2003-10-30
AU724591B2 (en) 2000-09-28
DE69818492T2 (de) 2004-07-22
EP1011329A4 (de) 2000-07-26
ATE250340T1 (de) 2003-10-15
CA2282264A1 (en) 1998-09-03
AU6668698A (en) 1998-09-18
EP1011329A1 (de) 2000-06-28
PT1011329E (pt) 2004-01-30
WO1998037765A1 (en) 1998-09-03
EP1011329B1 (de) 2003-09-24
JP2001513778A (ja) 2001-09-04
ES2207817T3 (es) 2004-06-01
US5902822A (en) 1999-05-11

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