DK1001961T3 - Substituerede derivater af tetrahydrofuran og fremgangsmåde til deres fremstilling - Google Patents
Substituerede derivater af tetrahydrofuran og fremgangsmåde til deres fremstillingInfo
- Publication number
- DK1001961T3 DK1001961T3 DK98945178T DK98945178T DK1001961T3 DK 1001961 T3 DK1001961 T3 DK 1001961T3 DK 98945178 T DK98945178 T DK 98945178T DK 98945178 T DK98945178 T DK 98945178T DK 1001961 T3 DK1001961 T3 DK 1001961T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- tetrahydrofuran
- substituted derivatives
- pharmaceutical
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
- C07H5/10—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19734392 | 1997-08-08 | ||
DE19820815 | 1998-05-09 | ||
PCT/EP1998/005025 WO1999007718A2 (fr) | 1997-08-08 | 1998-08-07 | Derives substitues du tetrahydropyrane, leur procede de production, leur utilisation comme medicaments ou agents diagnostiques, et medicaments les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1001961T3 true DK1001961T3 (da) | 2005-05-23 |
Family
ID=26038972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98945178T DK1001961T3 (da) | 1997-08-08 | 1998-08-07 | Substituerede derivater af tetrahydrofuran og fremgangsmåde til deres fremstilling |
Country Status (11)
Country | Link |
---|---|
US (1) | US6756489B1 (fr) |
EP (1) | EP1001961B1 (fr) |
JP (1) | JP4555466B2 (fr) |
AT (1) | ATE287895T1 (fr) |
AU (1) | AU9258798A (fr) |
CA (1) | CA2299295C (fr) |
DE (1) | DE59812518D1 (fr) |
DK (1) | DK1001961T3 (fr) |
ES (1) | ES2235362T3 (fr) |
PT (1) | PT1001961E (fr) |
WO (1) | WO1999007718A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002950657A0 (en) * | 2002-08-08 | 2002-09-12 | Alchemia Limited | Derivatives of monosaccharides for drug discovery |
AU2002951995A0 (en) | 2002-10-11 | 2002-10-31 | Alchemia Limited | Classes of compounds that interact with gpcrs |
CN101111243A (zh) * | 2005-02-04 | 2008-01-23 | 阿尔卡米亚有限公司 | 与整联蛋白相互作用的几类化合物 |
ES2272154B1 (es) * | 2005-04-13 | 2008-04-01 | Consejo Superior Investig. Cientificas | Fosfinitos tioglicosidos, procedimiento de preparacion y utilizacion como nuevos ligandos en catalisis asimetrica. |
EP2098238B1 (fr) * | 2007-01-12 | 2012-10-17 | The Noguchi Institute | Inhibiteur de la croissance de helicobacter pylori contenant un dérivé de monosaccharide comprenant un groupe n-acétylglucosaminyle lié en position alpha |
JP6047273B2 (ja) | 2008-02-08 | 2016-12-21 | プロセラ インコーポレイテッド | 胃腸のバイオフィルムの抑制および治療 |
EP2345656B1 (fr) | 2008-10-10 | 2018-05-02 | The Noguchi Institute | Dérivés de monosaccharide beta-liés à n-acétylglucosamine en tant qu'inhibiteurs de prolifération de bactérie helicobacter pylori |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2212014A1 (de) * | 1971-04-21 | 1972-10-26 | Deutsche Akademie der Wissenschaf ten zu Berlin, χ 1199 Berlin | Verfahren zur fermentativen Spaltung von Transportformen von Chemotherapeutika, insbesondere Cancerostatica |
GB1544908A (en) * | 1975-07-08 | 1979-04-25 | Chembiomed Ltd | Artificial oligosaccharide antigenic determinants |
GB1603609A (en) * | 1977-04-14 | 1981-11-25 | Chembiomed Ltd | O-protected 2-azido-2-deoxy-glycosyl nitrates |
US4386026A (en) * | 1981-04-20 | 1983-05-31 | Merck & Co., Inc. | Cell-specific glycopeptide ligands |
DE3220427A1 (de) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | Ss-d-galactosederivate, verfahren zu ihrer herstellung und ihre verwendung |
US4873322A (en) * | 1986-01-24 | 1989-10-10 | Ciba-Geigy Corporation | Saccharide derivatives and processes for their manufacture |
FR2633929B2 (fr) * | 1987-09-25 | 1995-05-24 | Picardie Universite | Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees |
US5079353A (en) | 1987-12-02 | 1992-01-07 | Chembiomed, Ltd. | Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation |
JPH06500781A (ja) * | 1990-09-21 | 1994-01-27 | イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー | ポリ(フルオロアルキル)糖試薬および表面改質のためのそれらの使用 |
CA2110707A1 (fr) * | 1991-06-10 | 1992-12-23 | Robert M. Ippolito | Composes lewis x et lewis a modifies par un oligosaccharide, immunosuppresseurs et tolerogeniques |
JPH0517359A (ja) * | 1991-07-10 | 1993-01-26 | Sanyo Chem Ind Ltd | 制ガン剤 |
US5552534A (en) * | 1991-08-22 | 1996-09-03 | The Trustees Of The University Of Pennsylvania | Non-Peptide peptidomimetics |
US5220008A (en) * | 1991-11-22 | 1993-06-15 | E. I. Du Pont De Nemours And Company | Oligosaccharide inhibitors for influenza virus |
US5268364A (en) * | 1991-12-12 | 1993-12-07 | The Biomembrane Institute | Method for inhibiting selectin-dependent adhesion of leukocytes and platelets by O-glycosylation modification |
US6297363B1 (en) * | 1993-02-12 | 2001-10-02 | Nomura Co., Ltd. | Glycoside indoles |
US5639866A (en) * | 1993-02-23 | 1997-06-17 | Princeton University | Single-step formation of multiple glycosidic linkages |
IL108748A0 (en) | 1993-02-23 | 1994-08-26 | Univ Princeton | Solution and solid-phase formation of glycosidic linkages |
AU7193494A (en) * | 1993-07-21 | 1995-02-20 | Oxford Glycosystems Ltd | Saccharides, their synthesis and use |
JPH0748264A (ja) * | 1993-08-06 | 1995-02-21 | Nippon Terupen Kagaku Kk | アルドース還元酵素阻害剤 |
US5616698A (en) * | 1994-01-10 | 1997-04-01 | University Of Toronto Innovations Foundation | Polymer-supported solution synthesis of oligosaccharides |
US5444050A (en) * | 1994-04-29 | 1995-08-22 | Texas Biotechnology Corporation | Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa |
WO1995029927A2 (fr) * | 1994-05-02 | 1995-11-09 | Biomira, Inc. | Procede de preparation de glycosides d'antigenes glucidiques associes aux tumeurs |
US5455240A (en) * | 1994-06-20 | 1995-10-03 | The Rockefeller University | Modulators of pneumococcal adhesion to cellular targets involving the platelet activating factor receptor, and uses thereof |
US5686426A (en) * | 1994-11-17 | 1997-11-11 | Bristol-Myers Squibb Company | Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors |
DE19503423A1 (de) * | 1995-02-03 | 1996-08-08 | Beiersdorf Ag | Antiadhäsive Wirkstoffe |
DE19517889C2 (de) * | 1995-05-16 | 1998-12-03 | Hoechst Ag | Verfahren zur gezielten Synthese von ß-glycosidisch verknüpften N-Acetylglucosaminderivaten |
AU719356B2 (en) * | 1995-12-07 | 2000-05-04 | Genzyme Limited | Solid phase organic synthesis |
US5716812A (en) * | 1995-12-12 | 1998-02-10 | The University Of British Columbia | Methods and compositions for synthesis of oligosaccharides, and the products formed thereby |
US20020165168A1 (en) * | 1995-12-16 | 2002-11-07 | Joachim Bunger | Use of sugar derivatives as antimicrobial, antimycotic and/or antiviral active substances |
EP0886640B1 (fr) * | 1996-01-30 | 2007-03-21 | GlycoMimetics, Inc. | ANALOGUES D'EPITOPES DE SIALYLE-LEWISa ET DE SIALYLE-LEWISx |
JP2000507247A (ja) * | 1996-03-21 | 2000-06-13 | プリンストン ユニバーシティー | グリコシル化に有用なスルフィニルヘキソース誘導体 |
DE19621177A1 (de) * | 1996-05-24 | 1997-11-27 | Basf Ag | Kohlenhydratderivate und ihre Synthese an fester Phase |
US5998595A (en) * | 1996-11-05 | 1999-12-07 | Wako Pure Chemical Industries, Ltd. | Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups |
US5780603A (en) * | 1996-11-15 | 1998-07-14 | Synsorb Biotech, Inc. | Combinatorial synthesis of carbohydrate libraries |
-
1998
- 1998-08-07 PT PT98945178T patent/PT1001961E/pt unknown
- 1998-08-07 US US09/485,233 patent/US6756489B1/en not_active Expired - Lifetime
- 1998-08-07 CA CA2299295A patent/CA2299295C/fr not_active Expired - Fee Related
- 1998-08-07 DE DE59812518T patent/DE59812518D1/de not_active Expired - Lifetime
- 1998-08-07 ES ES98945178T patent/ES2235362T3/es not_active Expired - Lifetime
- 1998-08-07 AT AT98945178T patent/ATE287895T1/de active
- 1998-08-07 AU AU92587/98A patent/AU9258798A/en not_active Abandoned
- 1998-08-07 EP EP98945178A patent/EP1001961B1/fr not_active Expired - Lifetime
- 1998-08-07 DK DK98945178T patent/DK1001961T3/da active
- 1998-08-07 JP JP2000506220A patent/JP4555466B2/ja not_active Expired - Fee Related
- 1998-08-07 WO PCT/EP1998/005025 patent/WO1999007718A2/fr active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DE59812518D1 (de) | 2005-03-03 |
JP4555466B2 (ja) | 2010-09-29 |
US6756489B1 (en) | 2004-06-29 |
WO1999007718A2 (fr) | 1999-02-18 |
EP1001961A2 (fr) | 2000-05-24 |
ATE287895T1 (de) | 2005-02-15 |
WO1999007718A3 (fr) | 1999-09-10 |
CA2299295C (fr) | 2010-11-30 |
CA2299295A1 (fr) | 1999-02-18 |
PT1001961E (pt) | 2005-04-29 |
ES2235362T3 (es) | 2005-07-01 |
EP1001961B1 (fr) | 2005-01-26 |
JP2001512737A (ja) | 2001-08-28 |
AU9258798A (en) | 1999-03-01 |
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