DK1001811T3 - Nanopartikler med en jernoxidholdig kerne omgivet af mindst to skaller - Google Patents

Nanopartikler med en jernoxidholdig kerne omgivet af mindst to skaller

Info

Publication number
DK1001811T3
DK1001811T3 DK98939520T DK98939520T DK1001811T3 DK 1001811 T3 DK1001811 T3 DK 1001811T3 DK 98939520 T DK98939520 T DK 98939520T DK 98939520 T DK98939520 T DK 98939520T DK 1001811 T3 DK1001811 T3 DK 1001811T3
Authority
DK
Denmark
Prior art keywords
core
shells
particles
iron oxide
shell
Prior art date
Application number
DK98939520T
Other languages
Danish (da)
English (en)
Inventor
Christoph Lesniak
Thomas Schiestel
Helmut Schmidt
Andreas Jordan
Original Assignee
Inst Neue Mat Gemein Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Neue Mat Gemein Gmbh filed Critical Inst Neue Mat Gemein Gmbh
Application granted granted Critical
Publication of DK1001811T3 publication Critical patent/DK1001811T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Hard Magnetic Materials (AREA)
  • Compounds Of Iron (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK98939520T 1997-06-20 1998-06-19 Nanopartikler med en jernoxidholdig kerne omgivet af mindst to skaller DK1001811T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19726282A DE19726282A1 (de) 1997-06-20 1997-06-20 Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern
PCT/EP1998/003761 WO1998058673A1 (fr) 1997-06-20 1998-06-19 Particules de l'ordre de grandeur du nanometre avec un noyau contenant de l'oxyde de fer et entoure d'au moins deux enveloppes

Publications (1)

Publication Number Publication Date
DK1001811T3 true DK1001811T3 (da) 2003-01-20

Family

ID=7833178

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98939520T DK1001811T3 (da) 1997-06-20 1998-06-19 Nanopartikler med en jernoxidholdig kerne omgivet af mindst to skaller

Country Status (10)

Country Link
US (2) US6541039B1 (fr)
EP (1) EP1001811B1 (fr)
JP (2) JP4902900B2 (fr)
CN (1) CN1211127C (fr)
AT (1) ATE223731T1 (fr)
DE (2) DE19726282A1 (fr)
DK (1) DK1001811T3 (fr)
ES (1) ES2181256T3 (fr)
PT (1) PT1001811E (fr)
WO (1) WO1998058673A1 (fr)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
DE19921088C2 (de) * 1999-04-30 2003-08-07 Magforce Applic Gmbh Stent zur Offenhaltung gangartiger Strukturen
DE19924138A1 (de) 1999-05-26 2000-11-30 Henkel Kgaa Lösbare Klebeverbindungen
DE19940220B4 (de) * 1999-08-19 2007-05-03 Magforce Nanotechnologies Ag Medizinisches Präparat zur Behandlung von Arthrose, Arthritis und anderen rheumatischen Gelenkerkrankungen
EP1228158B1 (fr) * 1999-08-24 2008-07-30 Henkel AG & Co. KGaA Collage par adhésif contenant des particules nanometriques
DE19951599A1 (de) 1999-10-27 2001-05-23 Henkel Kgaa Verfahren zur adhesiven Trennung von Klebeverbunden
AU2001236798B2 (en) * 2000-02-08 2004-11-04 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
DE10020376A1 (de) * 2000-04-26 2001-11-08 Inst Zelltechnologie E V Dynamische Marker
DE10037883A1 (de) 2000-08-03 2002-02-14 Henkel Kgaa Ferromagnetische Resonanzanregung und ihre Verwendung zur Erwärmung teilchengefüllter Substrate
DE10037884A1 (de) 2000-08-03 2002-02-21 Henkel Kgaa Verfahren zur beschleunigten Klebstoffaushärtung
DE10141674A1 (de) 2000-09-01 2002-03-14 Henkel Kgaa Reaktionsklebstoff mit mindestens einer mikroverkapselten Komponente
US6997863B2 (en) * 2001-07-25 2006-02-14 Triton Biosystems, Inc. Thermotherapy via targeted delivery of nanoscale magnetic particles
US7074175B2 (en) * 2001-07-25 2006-07-11 Erik Schroeder Handy Thermotherapy via targeted delivery of nanoscale magnetic particles
US7951061B2 (en) * 2001-07-25 2011-05-31 Allan Foreman Devices for targeted delivery of thermotherapy, and methods related thereto
US7731648B2 (en) * 2001-07-25 2010-06-08 Aduro Biotech Magnetic nanoscale particle compositions, and therapeutic methods related thereto
WO2003035108A1 (fr) * 2001-10-25 2003-05-01 Ttc Co., Ltd. Immunopotentialiseurs pour thermotherapie anticancereuse
DE10163399A1 (de) 2001-12-21 2003-07-10 Sustech Gmbh & Co Kg Nanopartikuläre Zubereitung
DE10205332B4 (de) * 2002-02-06 2004-02-12 Berlin Heart Ag Verfahren zur Herstellung von magnetischen Nanoteilchen
EP1576060A1 (fr) * 2002-12-09 2005-09-21 Itn Nanovation Gmbh Particules nanometriques noyau-enveloppe et leur production
AU2003900335A0 (en) * 2003-01-22 2003-02-13 Sirtex Medical Limited Microparticles for selectively targeted hyperthermia
DE10331439B3 (de) 2003-07-10 2005-02-03 Micromod Partikeltechnologie Gmbh Magnetische Nanopartikel mit verbesserten Magneteigenschaften
US20050119725A1 (en) * 2003-04-08 2005-06-02 Xingwu Wang Energetically controlled delivery of biologically active material from an implanted medical device
US20050107870A1 (en) * 2003-04-08 2005-05-19 Xingwu Wang Medical device with multiple coating layers
DE10326538A1 (de) * 2003-06-12 2005-01-05 Institut für Neue Materialien Gemeinnützige GmbH Abriebfeste optische Schichten und Formkörper
DE10344449A1 (de) * 2003-09-25 2005-04-28 Henkel Kgaa Klebstoff-Zusammensetzung mit Barriere-Eigenschaften
US20050090732A1 (en) * 2003-10-28 2005-04-28 Triton Biosystems, Inc. Therapy via targeted delivery of nanoscale particles
DE10359252A1 (de) * 2003-12-17 2005-07-28 Siemens Ag Navigierte Wärmebehandlung von Tumoren mit enzymumhüllten Eisenpartikeln
US20060018835A1 (en) * 2004-04-02 2006-01-26 General Electric Company Nanoparticles with inorganic core and methods of using them
US7407816B2 (en) 2004-05-07 2008-08-05 Gentius, Inc Isoelectric particles and uses thereof
US7842281B2 (en) * 2004-05-10 2010-11-30 The Florida State University Research Foundation Magnetic particle composition for therapeutic hyperthermia
US8728525B2 (en) 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
US20050260137A1 (en) * 2004-05-18 2005-11-24 General Electric Company Contrast agents for magnetic resonance imaging
DE102004038274A1 (de) * 2004-08-06 2006-03-16 Henkel Kgaa Bindemittel mit Barriere-Eigenschaften II
JP5194251B2 (ja) * 2004-08-25 2013-05-08 国立大学法人 鹿児島大学 複合微粒子及びその製造方法
DE102004052533A1 (de) 2004-10-15 2006-05-04 Mykhaylyk, Olga, Dr. Magnetische Partikel zur Verwendung in Therapie und Diagnostik
DE102005016873A1 (de) 2005-04-12 2006-10-19 Magforce Nanotechnologies Ag Nanopartikel-Wirstoff-Konjugate
EP1883425A1 (fr) * 2005-05-23 2008-02-06 Universite De Geneve Nanoparticules superparamagnetiques injectables destinees a un traitement par hyperthermie et a la formation d'un implant
DE102005039579B4 (de) * 2005-08-19 2022-06-30 Magforce Ag Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen
DE102005060834A1 (de) 2005-12-20 2007-06-28 Grönemeyer Holding GmbH & Co. KG Magnetfeldapplikator
DE102006007564A1 (de) * 2006-02-16 2007-08-30 Röhm Gmbh Nanoskalige superparamagnetische Poly(meth)acrylatpolymere
US8303931B2 (en) 2006-02-17 2012-11-06 Topass Gmbh Multimodal imaging using a three compartment polymer nanoparticle with cell specificity
WO2007115291A2 (fr) * 2006-04-04 2007-10-11 Freedom-2, Inc. Marquages tissulaires à l'aide de particules d'absorption discrètes
EP1852107A1 (fr) * 2006-04-19 2007-11-07 Nanobiotix Compositions contenant des nanoparticules magnétiques et leur utilisation
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
US9277295B2 (en) * 2006-06-16 2016-03-01 Cisco Technology, Inc. Securing media content using interchangeable encryption key
CN101484081A (zh) * 2006-07-04 2009-07-15 布拉科成像S.P.A.公司 生物组织尤其是肿瘤组织等的局部热切除装置
MX2009001226A (es) 2006-08-04 2009-03-20 Baxter Int Composicion basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nuevo inicio.
EP2117600B1 (fr) 2006-12-18 2012-12-05 Colorobbia Italia S.p.a. Nanoparticules magnétiques pour l'application en hyperthermie, sa préparation et son utilisation dans des produits de construction ayant une application pharmacologique
US20080167548A1 (en) * 2007-01-04 2008-07-10 Sorensen Alma G Tissue Alteration With MRI RF Field
US20110104073A1 (en) * 2007-01-18 2011-05-05 Qi Zeng Iron/Iron Oxide Nanoparticle and Use Thereof
ES2393639T3 (es) 2007-01-21 2012-12-26 Hemoteq Ag Producto médico para tratar cierres de conductos corporales y prevención de nuevos cierres
US20080281318A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for inductive heat treatment of body tissue
US20080281386A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for treating body tissue
US20090005734A1 (en) * 2007-06-27 2009-01-01 Tessaron Medical, Inc. Systems and methods for delivering particles into patient body
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
ES2320837B1 (es) * 2007-07-26 2010-03-04 Consejo Superior De Investigaciones Cientificas Dispositivo de hipertermia y su utilizacion con nanoparticulas.
US20090157069A1 (en) * 2007-12-06 2009-06-18 Curtis Tom Systems and methods for thermal treatment of body tissue
DE102008003615A1 (de) * 2008-01-09 2009-07-16 Magforce Nanotechnologies Ag Magnetische Transducer
DE102008008522A1 (de) 2008-02-11 2009-08-13 Magforce Nanotechnologies Ag Implantierbare Nanopartikel-enthaltende Produkte
KR101101832B1 (ko) 2008-05-20 2012-01-05 연세대학교 산학협력단 열방출 나노 물질
US8367427B2 (en) 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323615B2 (en) 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
DE102008064036B4 (de) 2008-12-22 2012-06-06 Heraeus Medical Gmbh Polymethylmethacrylat-Knochenzement-Zusammensetzung zur kontrollierten Hyperthermiebehandlung und deren Verwendung
WO2010102066A1 (fr) 2009-03-05 2010-09-10 Bend Research, Inc. Poudre de polymère de dextrane destinée à l'administration de produits pharmaceutiques par inhalation
US8293213B2 (en) * 2009-03-12 2012-10-23 Palo Alto Research Center Incorporated Method and apparatus for thrombus removal using magnetic particles
EP2246376B1 (fr) * 2009-04-27 2014-03-05 Leibniz-Institut für Polymerforschung Dresden e.V. Procédé de préparation de particules avec un polymère enveloppe conjugué
US10369256B2 (en) 2009-07-10 2019-08-06 Boston Scientific Scimed, Inc. Use of nanocrystals for drug delivery from a balloon
JP5933434B2 (ja) * 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 薬剤送達バルーンの製造方法
US9205155B2 (en) 2009-10-30 2015-12-08 General Electric Company Treating water insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, the so modified nanoparticles and their use as contrast agents
US8565892B2 (en) * 2009-10-31 2013-10-22 Qteris, Inc. Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment
US8715150B2 (en) 2009-11-02 2014-05-06 Pulse Therapeutics, Inc. Devices for controlling magnetic nanoparticles to treat fluid obstructions
DE102009058769A1 (de) 2009-12-16 2011-06-22 MagForce Nanotechnologies AG, 10589 Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
WO2011081712A1 (fr) * 2009-12-31 2011-07-07 Boston Scientific Scimed, Inc. Délivrance de médicament activée par cryothérapie et ballonnets de coupe
WO2011135397A1 (fr) * 2010-04-29 2011-11-03 University Of Calcutta Antiagrégant plaquettaire et procédés d'utilisation de celui-ci
US9669200B2 (en) 2010-08-06 2017-06-06 Boston Scientific Scimed, Inc. Systems and methods for the treatment of pelvic disorders including magnetic particulates
EP2611476B1 (fr) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Procédé d'enrobage de ballonnets d'administration de médicaments utilisant une mémoire d'enveloppe induite par la chaleur
US8815294B2 (en) 2010-09-03 2014-08-26 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives and a carrier material
KR101173867B1 (ko) 2010-10-28 2012-08-14 삼성에스디아이 주식회사 리튬 이차 전지
US9180172B2 (en) 2010-12-15 2015-11-10 Ams Research Corporation Treatment of Peyronies disease
US8979797B2 (en) 2010-12-16 2015-03-17 Ams Research Corporation High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics
KR20140022904A (ko) 2011-04-20 2014-02-25 유니버시티 오브 시드니 치료방법 및 그에 사용가능한 제제
US9060938B2 (en) 2011-05-10 2015-06-23 Bend Research, Inc. Pharmaceutical compositions of active agents and cationic dextran polymer derivatives
WO2013022458A1 (fr) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Procédés de conversion d'une substance médicamenteuse amorphe en une forme cristalline
RU2622025C2 (ru) 2011-08-10 2017-06-08 Магфорс Аг Агломерирование магнитных покрытых алкоксисиланом наночастиц
WO2013021039A1 (fr) 2011-08-11 2013-02-14 Basf Se Composition absorbant les microondes
WO2013028208A1 (fr) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Dispositif médical comprenant un revêtement médicamenteux cristallin
WO2013087920A1 (fr) 2011-12-16 2013-06-20 Nanobiotix Nanoparticules comprenant des matériaux métalliques et d'oxydes d'hafnium, leur préparation et utilisations
WO2013118783A1 (fr) * 2012-02-07 2013-08-15 国立大学法人筑波大学 Complexe hybride organique-inorganique de composé nitroxyde à poids moléculaire élevé et particule inorganique
US9883878B2 (en) 2012-05-15 2018-02-06 Pulse Therapeutics, Inc. Magnetic-based systems and methods for manipulation of magnetic particles
US9828047B2 (en) * 2012-07-06 2017-11-28 Mtd Products Inc Suspension and lock-out systems for a tracked vehicle
US9884662B2 (en) 2013-09-13 2018-02-06 Mtd Products Inc Suspension and lock-out systems for a partially tracked vehicle
CA3133490A1 (fr) 2013-09-13 2015-03-19 Mtd Products Inc Roue dentee d'entrainement pour un vehicule a chenille
WO2015056960A1 (fr) 2013-10-16 2015-04-23 주식회사 지니스 Composition de sensibilisation utilisant des ondes électromagnétiques pour la thérapie thermique de cancers, et cancérothérapie l'utilisant
US9902441B2 (en) 2014-08-21 2018-02-27 Mtd Products Inc Track drive
AU2016269146B2 (en) 2015-05-28 2021-01-28 Nanobiotix Nanoparticles for use as a therapeutic vaccine
US10155537B2 (en) 2015-05-29 2018-12-18 Mtd Products Inc Utility vehicle
WO2016205291A1 (fr) 2015-06-15 2016-12-22 Boston Scientific Scimed, Inc. Dispositifs et procédés de traitement de thermothérapie
DE102016006320A1 (de) 2016-05-25 2017-11-30 Carl Freudenberg Kg Fixierbare Flächengebilde
JP7051483B2 (ja) * 2017-03-29 2022-04-11 三洋化成工業株式会社 マイクロ波加熱溶着用樹脂組成物
US11511818B2 (en) 2017-09-05 2022-11-29 Mtd Products Inc Track drive
CA3073820A1 (fr) 2017-10-06 2019-04-11 Mtd Products Inc Outil d'entretien de pelouse a efficacite elevee et lame de coupe a efficacite elevee
US11918315B2 (en) 2018-05-03 2024-03-05 Pulse Therapeutics, Inc. Determination of structure and traversal of occlusions using magnetic particles

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4827945A (en) * 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
FR2618084B1 (fr) * 1987-07-15 1989-11-10 Rhone Poulenc Chimie Microspheres magnetisables a base de polysiloxane, leur procede de preparation et leur application en biologie
DE68926708T2 (de) * 1988-08-04 1996-10-31 Advanced Magnetics Inc Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri
US5460831A (en) * 1990-06-22 1995-10-24 The Regents Of The University Of California Targeted transfection nanoparticles
US5462751A (en) * 1990-06-22 1995-10-31 The Regeants Of The University Of California Biological and pharmaceutical agents having a nanomeric biodegradable core
DE4026978A1 (de) * 1990-08-25 1992-02-27 Bayer Ag Auf traegern angebrachte ein- oder mehrlagige schichtelemente und ihre herstellung
US5616311A (en) * 1991-01-15 1997-04-01 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
ATE207727T1 (de) * 1992-05-29 2001-11-15 Univ California Beschichtetes transplantat sowie herstellungsverfahren dafür
ES2176209T3 (es) * 1992-11-06 2002-12-01 Hisamitsu Pharmaceutical Co Preparacion farmaceutica oral liberable en el tracto digestivo inferior.
US5547748A (en) * 1994-01-14 1996-08-20 Sri International Carbon nanoencapsulates
US6103379A (en) * 1994-10-06 2000-08-15 Bar-Ilan University Process for the preparation of microspheres and microspheres made thereby
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
US6022500A (en) * 1995-09-27 2000-02-08 The United States Of America As Represented By The Secretary Of The Army Polymer encapsulation and polymer microsphere composites
DE19614136A1 (de) * 1996-04-10 1997-10-16 Inst Neue Mat Gemein Gmbh Verfahren zur Herstellung agglomeratfreier nanoskaliger Eisenoxidteilchen mit hydrolysebeständigem Überzug
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

Also Published As

Publication number Publication date
JP5116743B2 (ja) 2013-01-09
US6979466B2 (en) 2005-12-27
JP2002507964A (ja) 2002-03-12
US20030180370A1 (en) 2003-09-25
PT1001811E (pt) 2003-01-31
WO1998058673A1 (fr) 1998-12-30
CN1260724A (zh) 2000-07-19
CN1211127C (zh) 2005-07-20
JP4902900B2 (ja) 2012-03-21
EP1001811A1 (fr) 2000-05-24
ES2181256T3 (es) 2003-02-16
US6541039B1 (en) 2003-04-01
JP2010001308A (ja) 2010-01-07
EP1001811B1 (fr) 2002-09-11
DE59805535D1 (de) 2002-10-17
ATE223731T1 (de) 2002-09-15
DE19726282A1 (de) 1998-12-24

Similar Documents

Publication Publication Date Title
DK1001811T3 (da) Nanopartikler med en jernoxidholdig kerne omgivet af mindst to skaller
WO2001037721A3 (fr) Nanoparticules magnetiques pour la therapie selective
PT1157041E (pt) Anticorpos para terapia e diagnostico de cancro
ZA951299B (en) 5-substituted derivatives of mycophenolic acid
HUP0201757A2 (en) Compositoins and methods for the therapy and diagnosis of lung cancer
CA1244889A (fr) Dispositif d'hyperthermie
HUP0200763A2 (en) Compositions for the treatment and diagnosis of breast cancer and methods for their use
EP0758904A4 (fr) Procedes et compositions s'appliquant au traitement de la glomerulonephrite et d'autres maladies inflammatoires
GB2116424B (en) Water soluable glass articles, their manufacture, and their use in the treatment of ruminant animals
AU9312198A (en) Genes amplified in tumours, antibodies against the proteins encoded thereby, andtheir use in diagnosis and treatment of cancer
ATE530168T1 (de) Magnetische nanoteilchen-zusammensetzungen und ihre verwendungen
PH31406A (en) 6-Substituted mycophenolic acid and derivatives.
IL110464A0 (en) Novel proteins for the diagnosis, imaging, and therapy of human cancer
ZA982968B (en) Compositions and methods for the treatment and diagnosis of breast cancer
WO2021030225A3 (fr) Variants de capsides aav pour le ciblage de cellules de glioblastome humain
CA2098113A1 (fr) Substances de nature polypeptidique pour usage therapeutique chez l'homme
MXPA02011563A (es) Composicionesy metodos para la terapia y diagnostico de cancer de seno.
EP1351967A4 (fr) Compositions et procedes pour la therapie et le diagnostic du cancer des poumons
AU2002218977A1 (en) Novel marker for the diagnosis and therapy of tumours
Carmichael Sex offenders
of Head Practice care guidance for clinicians participating in the management of head and neck cancer patients in the UK. Drawn up by a Consensus Group of Practising Clinicians
AU1388999A (en) The use of nitric oxide generations for the treatment of dry eye disorders
ZA95508B (en) Use of flavolignans as adjuvants in tumour therapy
HK1046019A1 (zh) 診斷和治療肺癌的組合物和方法
Ryasenko et al. Influence of Cs and Sr isotopes on blood producing tissue of animals in 30-km Chernobyl zone