DK0917874T3 - Fremgangsmåde til den langsigtede reduktion af legemsfedtdepoter, insulinresistens, hyperinsulimia og hypoglykæmi hos hvirveldyr - Google Patents

Fremgangsmåde til den langsigtede reduktion af legemsfedtdepoter, insulinresistens, hyperinsulimia og hypoglykæmi hos hvirveldyr

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Publication number
DK0917874T3
DK0917874T3 DK98110831T DK98110831T DK0917874T3 DK 0917874 T3 DK0917874 T3 DK 0917874T3 DK 98110831 T DK98110831 T DK 98110831T DK 98110831 T DK98110831 T DK 98110831T DK 0917874 T3 DK0917874 T3 DK 0917874T3
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DK
Denmark
Prior art keywords
insulin resistance
long term
treatment
peak
body fat
Prior art date
Application number
DK98110831T
Other languages
English (en)
Inventor
Anthony Cincotta
Albert Meier
Original Assignee
Univ Louisiana State
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Filing date
Publication date
Application filed by Univ Louisiana State filed Critical Univ Louisiana State
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Publication of DK0917874T3 publication Critical patent/DK0917874T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
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    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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DK98110831T 1990-01-10 1991-01-07 Fremgangsmåde til den langsigtede reduktion af legemsfedtdepoter, insulinresistens, hyperinsulimia og hypoglykæmi hos hvirveldyr DK0917874T3 (da)

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US46332790A 1990-01-10 1990-01-10

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DK0917874T3 true DK0917874T3 (da) 2008-07-28

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Family Applications (2)

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DK91300083T DK0440333T3 (da) 1990-01-10 1991-01-07 Anvendelse af prolactin-inhiberende forbindelser til genindstilling af prolactin-døgnrytmen
DK98110831T DK0917874T3 (da) 1990-01-10 1991-01-07 Fremgangsmåde til den langsigtede reduktion af legemsfedtdepoter, insulinresistens, hyperinsulimia og hypoglykæmi hos hvirveldyr

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DK91300083T DK0440333T3 (da) 1990-01-10 1991-01-07 Anvendelse af prolactin-inhiberende forbindelser til genindstilling af prolactin-døgnrytmen

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Country Link
US (2) US5496803A (da)
EP (2) EP0917874B1 (da)
JP (2) JP2896939B2 (da)
AT (2) ATE174793T1 (da)
CA (1) CA2030174C (da)
DE (2) DE69133595T2 (da)
DK (2) DK0440333T3 (da)
ES (2) ES2306465T3 (da)
GR (1) GR3029276T3 (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731287A (en) * 1988-05-10 1998-03-24 Louisiana State University And Agricultural And Mechanical College Process for the long term reduction of body fat stores, insulin resistance, and hyperinsulinemia in vertebrates
US5344832A (en) * 1990-01-10 1994-09-06 The Board Of Supervisors Of Louisiana University And Agricultural And Mechanical College Method for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hyperglycemia in vertebrates
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EP0440333B1 (en) 1998-12-23
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CA2030174A1 (en) 1991-07-11
GR3029276T3 (en) 1999-05-28
ATE174793T1 (de) 1999-01-15
JP2896939B2 (ja) 1999-05-31
EP0440333A2 (en) 1991-08-07
EP0917874B1 (en) 2008-04-09
DE69130651D1 (de) 1999-02-04
DE69133595D1 (de) 2008-05-21
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CA2030174C (en) 1996-12-24
DE69130651T2 (de) 1999-05-06
EP0440333A3 (en) 1992-06-17
US5866584A (en) 1999-02-02
EP0917874A1 (en) 1999-05-26
ATE391506T1 (de) 2008-04-15
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JPH0748257A (ja) 1995-02-21
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