DK0906276T3 - Nye vitamin D analoger - Google Patents
Nye vitamin D analogerInfo
- Publication number
- DK0906276T3 DK0906276T3 DK97924929T DK97924929T DK0906276T3 DK 0906276 T3 DK0906276 T3 DK 0906276T3 DK 97924929 T DK97924929 T DK 97924929T DK 97924929 T DK97924929 T DK 97924929T DK 0906276 T3 DK0906276 T3 DK 0906276T3
- Authority
- DK
- Denmark
- Prior art keywords
- stands
- alkyl radical
- aryl
- hydrogen
- formula
- Prior art date
Links
- 229930003316 Vitamin D Natural products 0.000 title 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
- 235000019166 vitamin D Nutrition 0.000 title 1
- 239000011710 vitamin D Substances 0.000 title 1
- 150000003710 vitamin D derivatives Chemical class 0.000 title 1
- 229940046008 vitamin d Drugs 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- AIDS & HIV (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9611603.3A GB9611603D0 (en) | 1996-06-04 | 1996-06-04 | Chemical compounds |
| PCT/DK1997/000225 WO1997046522A1 (en) | 1996-06-04 | 1997-05-15 | Novel vitamin d analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0906276T3 true DK0906276T3 (da) | 2002-12-02 |
Family
ID=10794707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97924929T DK0906276T3 (da) | 1996-06-04 | 1997-05-15 | Nye vitamin D analoger |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6197982B1 (Direct) |
| EP (1) | EP0906276B1 (Direct) |
| JP (1) | JP2000511894A (Direct) |
| CN (1) | CN1217926C (Direct) |
| AT (1) | ATE221875T1 (Direct) |
| AU (1) | AU714223B2 (Direct) |
| CZ (1) | CZ296255B6 (Direct) |
| DE (1) | DE69714590T2 (Direct) |
| DK (1) | DK0906276T3 (Direct) |
| ES (1) | ES2179343T3 (Direct) |
| GB (1) | GB9611603D0 (Direct) |
| NZ (1) | NZ332237A (Direct) |
| PL (1) | PL186804B1 (Direct) |
| PT (1) | PT906276E (Direct) |
| RO (1) | RO120133B1 (Direct) |
| RU (1) | RU2165413C2 (Direct) |
| WO (1) | WO1997046522A1 (Direct) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090098065A1 (en) * | 2000-01-11 | 2009-04-16 | Avikam Harel | Composition and methods for the treatment of skin disorders |
| EP1458678A1 (en) * | 2002-11-18 | 2004-09-22 | Teva Pharmaceutical Industries Limited | A crystallization method for purification of calcipotriene |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| KR20110113664A (ko) * | 2006-08-29 | 2011-10-17 | 테바 파마슈티컬 인더스트리즈 리미티드 | 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물 |
| US8377913B2 (en) * | 2007-11-20 | 2013-02-19 | Abbvie Inc. | Vitamin D receptor activators and methods of making |
| AU2010208323B2 (en) | 2009-01-27 | 2016-03-10 | Berg Llc | Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy |
| EP2464357B1 (en) | 2009-08-14 | 2019-05-22 | Berg LLC | Vitamin d3 and analogs thereof for treating alopecia |
| US20120322776A1 (en) * | 2009-12-22 | 2012-12-20 | Leo Pharma A/S | Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants |
| CN102770121B (zh) * | 2009-12-22 | 2014-10-15 | 利奥制药有限公司 | 包含溶剂混合物和维生素d衍生物或类似物的药物组合物 |
| PT2360145E (pt) * | 2010-01-26 | 2012-06-27 | Hybrigenics Sa | Novo processo para isomerização de estruturas bicíclicas condensadas e preparação de análogos de vitamina d que as contêm |
| HUE025554T2 (en) * | 2010-10-25 | 2016-02-29 | Teijin Pharma Ltd | Vitamin D3-23-in derivative |
| SG10201709894RA (en) | 2013-05-29 | 2018-01-30 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
| AU2016234990B2 (en) | 2015-10-02 | 2018-12-06 | Lg Electronics Inc. | Washing machine and method for controlling the same |
| AU2016234988B2 (en) | 2015-10-02 | 2018-08-02 | Lg Electronics Inc. | Washing machine |
| US20170096769A1 (en) | 2015-10-02 | 2017-04-06 | Lg Electronics Inc. | Method for controlling washing machine |
| US12351551B2 (en) * | 2019-11-27 | 2025-07-08 | Yonsung Fine Chemical Co., Ltd. | Method for producing maxacalcitol, and intermediate therefor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU688125A3 (ru) * | 1974-12-09 | 1979-09-25 | Тейдзин Лимитед (Фирма) | Способ получени 1 , 24/ /диокси-холекальциферола или 1 , 24 / /-диоксихолекальциферола или их производных |
| EP0296800B1 (en) | 1987-06-23 | 1991-10-16 | Yamanouchi Pharmaceutical Co. Ltd. | Vitamin d3 derivatives |
| GB9206648D0 (en) | 1992-03-26 | 1992-05-06 | Leo Pharm Prod Ltd | Chemical compounds |
| GB9223061D0 (en) | 1992-11-04 | 1992-12-16 | Leo Pharm Prod Ltd | Chemical compounds |
| US5552392A (en) | 1993-11-03 | 1996-09-03 | Wisconsin Alumni Research Foundation | Method of treating hypoparathyroidism with (20S) vitamin D compounds |
-
1996
- 1996-06-04 GB GBGB9611603.3A patent/GB9611603D0/en active Pending
-
1997
- 1997-05-15 CZ CZ0397198A patent/CZ296255B6/cs not_active IP Right Cessation
- 1997-05-15 RU RU98121401/04A patent/RU2165413C2/ru not_active IP Right Cessation
- 1997-05-15 ES ES97924929T patent/ES2179343T3/es not_active Expired - Lifetime
- 1997-05-15 DE DE69714590T patent/DE69714590T2/de not_active Expired - Lifetime
- 1997-05-15 DK DK97924929T patent/DK0906276T3/da active
- 1997-05-15 US US09/202,200 patent/US6197982B1/en not_active Expired - Fee Related
- 1997-05-15 PL PL97329941A patent/PL186804B1/pl not_active IP Right Cessation
- 1997-05-15 WO PCT/DK1997/000225 patent/WO1997046522A1/en not_active Ceased
- 1997-05-15 AU AU30256/97A patent/AU714223B2/en not_active Ceased
- 1997-05-15 RO RO98-01607A patent/RO120133B1/ro unknown
- 1997-05-15 CN CN971950202A patent/CN1217926C/zh not_active Expired - Fee Related
- 1997-05-15 EP EP97924929A patent/EP0906276B1/en not_active Expired - Lifetime
- 1997-05-15 PT PT97924929T patent/PT906276E/pt unknown
- 1997-05-15 NZ NZ332237A patent/NZ332237A/xx not_active IP Right Cessation
- 1997-05-15 AT AT97924929T patent/ATE221875T1/de active
- 1997-05-15 JP JP10500106A patent/JP2000511894A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0906276B1 (en) | 2002-08-07 |
| PL329941A1 (en) | 1999-04-26 |
| RU2165413C2 (ru) | 2001-04-20 |
| GB9611603D0 (en) | 1996-08-07 |
| CN1217926C (zh) | 2005-09-07 |
| RO120133B1 (ro) | 2005-09-30 |
| EP0906276A1 (en) | 1999-04-07 |
| WO1997046522A1 (en) | 1997-12-11 |
| DE69714590T2 (de) | 2003-04-24 |
| AU714223B2 (en) | 1999-12-23 |
| CZ296255B6 (cs) | 2006-02-15 |
| AU3025697A (en) | 1998-01-05 |
| ES2179343T3 (es) | 2003-01-16 |
| ATE221875T1 (de) | 2002-08-15 |
| CZ397198A3 (cs) | 1999-03-17 |
| JP2000511894A (ja) | 2000-09-12 |
| DE69714590D1 (de) | 2002-09-12 |
| PL186804B1 (pl) | 2004-02-27 |
| CN1219928A (zh) | 1999-06-16 |
| HK1019733A1 (en) | 2000-02-25 |
| PT906276E (pt) | 2002-12-31 |
| NZ332237A (en) | 2000-07-28 |
| US6197982B1 (en) | 2001-03-06 |
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