DK0885218T3 - Muscarinreceptorantagonistisk oxa- og thiadiazol - Google Patents

Muscarinreceptorantagonistisk oxa- og thiadiazol

Info

Publication number
DK0885218T3
DK0885218T3 DK97902337T DK97902337T DK0885218T3 DK 0885218 T3 DK0885218 T3 DK 0885218T3 DK 97902337 T DK97902337 T DK 97902337T DK 97902337 T DK97902337 T DK 97902337T DK 0885218 T3 DK0885218 T3 DK 0885218T3
Authority
DK
Denmark
Prior art keywords
thiadiazole
oxa
receptor antagonistic
muscarin receptor
muscarin
Prior art date
Application number
DK97902337T
Other languages
Danish (da)
English (en)
Inventor
Alexander Roderick Mackenzie
Anthony Wood
Robert John Bass
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Application granted granted Critical
Publication of DK0885218T3 publication Critical patent/DK0885218T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
DK97902337T 1996-02-22 1997-02-04 Muscarinreceptorantagonistisk oxa- og thiadiazol DK0885218T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9603755.1A GB9603755D0 (en) 1996-02-22 1996-02-22 Therapeutic agents
PCT/EP1997/000525 WO1997030994A1 (en) 1996-02-22 1997-02-04 Oxa- and thia-diazole muscarinic receptor antagonists

Publications (1)

Publication Number Publication Date
DK0885218T3 true DK0885218T3 (da) 2001-05-28

Family

ID=10789217

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97902337T DK0885218T3 (da) 1996-02-22 1997-02-04 Muscarinreceptorantagonistisk oxa- og thiadiazol

Country Status (43)

Country Link
US (1) US5977142A (es)
EP (1) EP0885218B1 (es)
JP (1) JP3148252B2 (es)
KR (1) KR100315934B1 (es)
CN (1) CN1089340C (es)
AP (1) AP751A (es)
AR (1) AR005916A1 (es)
AT (1) ATE200899T1 (es)
AU (1) AU712230B2 (es)
BG (2) BG63971B1 (es)
BR (1) BR9707733A (es)
CA (1) CA2247164C (es)
CO (1) CO4650040A1 (es)
CZ (1) CZ292650B6 (es)
DE (1) DE69704701T2 (es)
DK (1) DK0885218T3 (es)
DZ (1) DZ2181A1 (es)
ES (1) ES2156357T3 (es)
GB (1) GB9603755D0 (es)
GR (1) GR3036032T3 (es)
HK (1) HK1018274A1 (es)
HN (1) HN1997000020A (es)
HR (1) HRP970098B1 (es)
HU (1) HUP9900501A3 (es)
ID (1) ID16642A (es)
IL (1) IL125413A (es)
IS (1) IS4803A (es)
MY (1) MY129729A (es)
NO (1) NO313414B1 (es)
NZ (1) NZ331039A (es)
OA (1) OA10838A (es)
PE (1) PE42798A1 (es)
PL (1) PL186879B1 (es)
PT (1) PT885218E (es)
RU (1) RU2162848C2 (es)
SK (1) SK283461B6 (es)
TN (1) TNSN97039A1 (es)
TR (1) TR199801644T2 (es)
TW (1) TW492961B (es)
UA (1) UA61068C2 (es)
WO (1) WO1997030994A1 (es)
YU (1) YU35698A (es)
ZA (1) ZA971513B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
GB0510141D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B3
GB0510139D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B1
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
WO2008017827A2 (en) * 2006-08-08 2008-02-14 Argenta Discovery Limited Azole and thiazole derivatives and their uses
WO2008023157A1 (en) * 2006-08-21 2008-02-28 Argenta Discovery Limited Nitrogen containing heterocyclic compounds useful as m3-receptor modulators
WO2008096093A1 (en) * 2007-02-06 2008-08-14 Argenta Discovery Ltd. Oxazole and thiazole derivatives and their uses
GB0702414D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd Oxazole and thiazole derivatives and their uses 2
GB0702416D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New combination
BRPI0807004A2 (pt) * 2007-02-07 2014-04-15 Argenta Discovery Ltd Sal
GB0702382D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New salt
GB0702385D0 (en) * 2007-02-07 2007-03-21 Argenta Discovery Ltd New combination
RU2009133258A (ru) * 2007-02-15 2011-03-20 Арджента Дискавери Лимитед (Gb) Гетероциклические производные в качестве ингибиторов мускариновых рецепторов типа мз
WO2009098453A1 (en) * 2008-02-06 2009-08-13 Astrazeneca Ab Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists
US8263623B2 (en) 2008-07-11 2012-09-11 Pfizer Inc. Triazol derivatives useful for the treatment of diseases
WO2010018352A1 (en) * 2008-08-12 2010-02-18 Argenta Discovery Limited Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated
JP2014065387A (ja) * 2012-09-25 2014-04-17 Showa Corp 自動二輪車の車高調整装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL88846A0 (en) * 1988-01-08 1989-07-31 Merck Sharp & Dohme Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
EP0619814A1 (en) * 1991-12-31 1994-10-19 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
TW360653B (en) * 1995-03-01 1999-06-11 Janssen Pharmaceutica Nv A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition

Also Published As

Publication number Publication date
ZA971513B (en) 1998-08-21
PT885218E (pt) 2001-08-30
KR19990087143A (ko) 1999-12-15
TNSN97039A1 (fr) 2005-03-15
TW492961B (en) 2002-07-01
NZ331039A (en) 1999-10-28
BG63971B1 (bg) 2003-08-29
KR100315934B1 (ko) 2002-03-21
BG102699A (en) 1999-09-30
CO4650040A1 (es) 1998-09-03
ATE200899T1 (de) 2001-05-15
ID16642A (id) 1997-10-23
HUP9900501A2 (hu) 1999-06-28
DE69704701T2 (de) 2001-08-16
SK283461B6 (sk) 2003-08-05
DE69704701D1 (de) 2001-06-07
DZ2181A1 (fr) 2002-12-01
GB9603755D0 (en) 1996-04-24
MY129729A (en) 2007-04-30
OA10838A (en) 2001-08-13
CA2247164C (en) 2004-11-16
PL328633A1 (en) 1999-02-15
CN1211981A (zh) 1999-03-24
AR005916A1 (es) 1999-07-21
PE42798A1 (es) 1998-08-18
WO1997030994A1 (en) 1997-08-28
HRP970098B1 (en) 2001-12-31
TR199801644T2 (xx) 1998-11-23
UA61068C2 (en) 2003-11-17
EP0885218B1 (en) 2001-05-02
JPH11504051A (ja) 1999-04-06
AU712230B2 (en) 1999-11-04
NO983871L (no) 1998-08-21
ES2156357T3 (es) 2001-06-16
YU35698A (sh) 1999-07-28
NO313414B1 (no) 2002-09-30
HN1997000020A (es) 1997-06-05
CZ292650B6 (cs) 2003-11-12
CZ267898A3 (cs) 1999-08-11
HRP970098A2 (en) 1999-04-30
BR9707733A (pt) 1999-07-27
IL125413A (en) 2002-09-12
EP0885218A1 (en) 1998-12-23
AP9700930A0 (en) 1997-04-30
PL186879B1 (pl) 2004-03-31
IL125413A0 (en) 1999-03-12
HK1018274A1 (en) 1999-12-17
AP751A (en) 1999-07-12
AU1601497A (en) 1997-09-10
JP3148252B2 (ja) 2001-03-19
NO983871D0 (no) 1998-08-21
HUP9900501A3 (en) 2001-02-28
IS4803A (is) 1998-07-21
US5977142A (en) 1999-11-02
CN1089340C (zh) 2002-08-21
SK112398A3 (en) 2000-04-10
CA2247164A1 (en) 1997-08-28
RU2162848C2 (ru) 2001-02-10
GR3036032T3 (en) 2001-09-28

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