DK0877600T3 - Konserveringssystem til farmaceutiske præparater indeholdende cyclodextrine - Google Patents

Konserveringssystem til farmaceutiske præparater indeholdende cyclodextrine

Info

Publication number
DK0877600T3
DK0877600T3 DK97936482T DK97936482T DK0877600T3 DK 0877600 T3 DK0877600 T3 DK 0877600T3 DK 97936482 T DK97936482 T DK 97936482T DK 97936482 T DK97936482 T DK 97936482T DK 0877600 T3 DK0877600 T3 DK 0877600T3
Authority
DK
Denmark
Prior art keywords
pct
alkyl
alkene
sec
pharmaceutical preparations
Prior art date
Application number
DK97936482T
Other languages
English (en)
Inventor
J Castillo Ernesto
L Espino Ramon
Original Assignee
Alcon Mfg Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Mfg Ltd filed Critical Alcon Mfg Ltd
Application granted granted Critical
Publication of DK0877600T3 publication Critical patent/DK0877600T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
DK97936482T 1996-08-09 1997-08-08 Konserveringssystem til farmaceutiske præparater indeholdende cyclodextrine DK0877600T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2245396P 1996-08-09 1996-08-09
PCT/US1997/014119 WO1998006381A1 (en) 1996-08-09 1997-08-08 Preservative systems for pharmaceutical compositions containing cyclodextrins

Publications (1)

Publication Number Publication Date
DK0877600T3 true DK0877600T3 (da) 2004-02-02

Family

ID=21809676

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97936482T DK0877600T3 (da) 1996-08-09 1997-08-08 Konserveringssystem til farmaceutiske præparater indeholdende cyclodextrine

Country Status (11)

Country Link
US (1) US5985310A (da)
EP (1) EP0877600B1 (da)
JP (1) JP4215277B2 (da)
AT (1) ATE252369T1 (da)
AU (1) AU709580B2 (da)
CA (1) CA2232435C (da)
DE (1) DE69725704T2 (da)
DK (1) DK0877600T3 (da)
ES (1) ES2207748T3 (da)
PT (1) PT877600E (da)
WO (1) WO1998006381A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802864D0 (sv) * 1998-08-27 1998-08-27 Pharmacia & Upjohn Ab Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder
JP2002523475A (ja) * 1998-09-02 2002-07-30 アラーガン・セイルズ・インコーポレイテッド 防腐したシクロデキストリン含有組成物
ATE255909T1 (de) 1998-10-27 2003-12-15 Alcon Lab Inc Konservierungssystem für topisch verabreichbare pharmazeutische zusammensetzungen
ATE416791T1 (de) * 2000-05-02 2008-12-15 Theravance Inc Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält
US7034013B2 (en) * 2001-03-20 2006-04-25 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
MXPA04008173A (es) * 2002-02-22 2004-11-26 Pharmacia Corp Formulaciones de farmaco antibiotico oftalmico que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio.
EP1747023B2 (en) 2004-05-04 2016-03-09 The Board of Trustees of The Leland Stanford Junior University Methods and compositions for reducing hcv viral genome amounts in a target cell
US6969706B1 (en) * 2004-05-12 2005-11-29 Allergan, Inc. Preserved pharmaceutical compositions comprising cyclodextrins
WO2006040839A1 (ja) * 2004-10-15 2006-04-20 Advanced Medicine Research Institute 眼疾患処置用点眼剤及びキット
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
US20070238789A1 (en) * 2006-03-31 2007-10-11 Chin-Ming Chang Prednisolone acetate compositions
AR066901A1 (es) * 2007-05-18 2009-09-23 Alcon Mfg Ltd Composiciones fodfolipidicas para elcuidado de lentes de contacto y conservacion de composiciones farmaceuticas
CA2729613C (en) 2008-03-03 2017-02-07 Tosk, Incorporated Methotrexate adjuvants to reduce toxicity and methods for using the same
BRPI0912302A2 (pt) * 2008-05-28 2015-10-20 Alcon Res Ltd emulsões autopreservados
TW201010727A (en) * 2008-09-03 2010-03-16 Alcon Res Ltd Pharmaceutical composition having relatively low ionic strength
JP2012513393A (ja) * 2008-12-22 2012-06-14 アルコン リサーチ， リミテッド 眼の後区に、有効濃度の活性剤を送達するための、眼の局部に用いる溶液の組成物
US8569254B2 (en) 2010-12-10 2013-10-29 National Yang Ming University Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
AU2016279804B2 (en) 2015-06-15 2019-03-07 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated conditions
WO2023148231A1 (en) 2022-02-02 2023-08-10 Oculis SA Multidose ophthalmic compositions

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209449A (en) * 1978-11-30 1980-06-24 Mona Industries Phosphate quaternary compounds
US4407791A (en) * 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
JPS59152320A (ja) * 1983-02-17 1984-08-31 Takeda Chem Ind Ltd 水性製剤
DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
JPS60149530A (ja) * 1984-01-13 1985-08-07 Takeda Chem Ind Ltd 水性製剤
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
US4870060A (en) * 1985-03-15 1989-09-26 Janssen Pharmaceutica Derivatives of γ-cylodextrin
US5322667A (en) * 1987-03-31 1994-06-21 Sherman Pharmaceuticals, Inc. Preservative system for ophthalmic and contact lens solutions and method for cleaning disinfecting and storing contact lenses
JPS6416718A (en) * 1987-06-22 1989-01-20 Three S Tech Bv Skin adhesive patch
US5298182A (en) * 1989-01-31 1994-03-29 Ciba-Geigy Corporation Rapid ophthalmic glycol/lower alkanol cleaning and disinfecting solution and method
US5089053A (en) * 1989-11-09 1992-02-18 Polymer Technology Corporation Contact lens cleaning material and method
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5286719A (en) * 1991-10-28 1994-02-15 Mona Industries, Inc. Phospholipid virucidal compositions
JPH0616547A (ja) * 1992-07-01 1994-01-25 Wakamoto Pharmaceut Co Ltd 消炎点眼剤
US5683709A (en) * 1994-05-05 1997-11-04 Ciba Vision Corporation Poly(benzalkonium salt) as an anti-microbial agent for aqueous drug compositions
EP0708646A1 (en) * 1994-05-06 1996-05-01 Alcon Laboratories, Inc. Use of vitamin e tocopheryl derivatives in ophthalmic compositions
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
JP3297969B2 (ja) * 1994-12-26 2002-07-02 ライオン株式会社 点眼剤
JPH08175985A (ja) * 1994-12-26 1996-07-09 Lion Corp 点眼剤
EP0807434B1 (en) * 1995-01-20 2002-04-10 Wakamoto Pharmaceutical Co., Ltd. Anti-inflammatory eyedrops
TW434023B (en) * 1995-09-18 2001-05-16 Novartis Ag Preserved ophthalmic composition

Also Published As

Publication number Publication date
EP0877600B1 (en) 2003-10-22
US5985310A (en) 1999-11-16
JPH11513045A (ja) 1999-11-09
ES2207748T3 (es) 2004-06-01
WO1998006381A1 (en) 1998-02-19
DE69725704T2 (de) 2004-05-13
ATE252369T1 (de) 2003-11-15
PT877600E (pt) 2004-02-27
DE69725704D1 (de) 2003-11-27
JP4215277B2 (ja) 2009-01-28
CA2232435A1 (en) 1998-02-19
EP0877600A1 (en) 1998-11-18
AU3914097A (en) 1998-03-06
CA2232435C (en) 2006-11-14
AU709580B2 (en) 1999-09-02

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