DK0828726T3 - Tricykliske inhibitorer af matrixmetalloproteinaser - Google Patents
Tricykliske inhibitorer af matrixmetalloproteinaserInfo
- Publication number
- DK0828726T3 DK0828726T3 DK96913185T DK96913185T DK0828726T3 DK 0828726 T3 DK0828726 T3 DK 0828726T3 DK 96913185 T DK96913185 T DK 96913185T DK 96913185 T DK96913185 T DK 96913185T DK 0828726 T3 DK0828726 T3 DK 0828726T3
- Authority
- DK
- Denmark
- Prior art keywords
- matrix metalloproteinases
- gelatinase
- inhibitors
- tricyclic inhibitors
- tricyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/460,436 US5665764A (en) | 1995-06-02 | 1995-06-02 | Tricyclic inhibitors of matrix metalloproteinases |
| US08/460,437 US5627206A (en) | 1995-06-02 | 1995-06-02 | Tricyclic inhibitor of matrix metalloproteinases |
| PCT/US1996/005830 WO1996038434A1 (fr) | 1995-06-02 | 1996-04-26 | Inhibiteurs tricycliques de metalloproteinases matricielles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0828726T3 true DK0828726T3 (da) | 2002-01-21 |
Family
ID=27039692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96913185T DK0828726T3 (da) | 1995-06-02 | 1996-04-26 | Tricykliske inhibitorer af matrixmetalloproteinaser |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0828726B1 (fr) |
| JP (1) | JPH11506097A (fr) |
| KR (1) | KR19990022171A (fr) |
| AT (1) | ATE206416T1 (fr) |
| AU (1) | AU717570B2 (fr) |
| CA (1) | CA2220040A1 (fr) |
| DE (1) | DE69615680T2 (fr) |
| DK (1) | DK0828726T3 (fr) |
| ES (1) | ES2165496T3 (fr) |
| MX (1) | MX9708728A (fr) |
| PT (1) | PT828726E (fr) |
| WO (1) | WO1996038434A1 (fr) |
| ZA (1) | ZA964508B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9711988A (pt) * | 1996-09-04 | 1999-08-24 | Warner Lambert Co | Inibidores de metaloproteinase de matriz e seus empregos terap-uticos |
| US6624177B1 (en) | 1996-09-04 | 2003-09-23 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
| BR9712794A (pt) | 1996-09-04 | 1999-12-14 | Warner Lambert Co | Compostos para e um método de inibição de metaloproteinases matriciais |
| MXPA99001974A (es) * | 1996-12-09 | 2002-03-27 | Warner Lambert Co | Metodo para tratar y prevenir fallas cardiacas y dilatacion ventricular. |
| SI0946166T1 (en) * | 1996-12-17 | 2004-06-30 | Warner-Lambert Company Llc | Use of matrix metalloproteinase inhibitors for promoting wound healing |
| JP2001507342A (ja) * | 1996-12-17 | 2001-06-05 | ワーナー−ランバート・コンパニー | 神経疾患の治療および創傷治癒を促進するためのマトリックスメタロプロテイナーゼ阻害剤の使用 |
| US6399612B1 (en) | 1997-10-06 | 2002-06-04 | Warner-Lambert Company | Heteroaryl butyric acids and their derivatives as inhibitors of matrix metalloproteinases |
| AU4229499A (en) | 1998-07-30 | 2000-02-21 | Warner-Lambert Company | Tricyclic heteroaromatics and their derivatives as inhibitors of matrix metalloproteinases |
| JP2002521478A (ja) | 1998-07-30 | 2002-07-16 | ワーナー−ランバート・カンパニー | マトリックスメタロプロテイナーゼの阻害剤としての３環式スルホンアミド及びそれらの誘導体 |
| DOP2002000334A (es) * | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Pirimidinas biciclicas como inhibidores de metaloproteinasas de matriz |
| WO2004014880A1 (fr) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Derives de chromone inhibiteurs de metalloproteinase de matrice |
| CA2661299A1 (fr) * | 2006-08-22 | 2008-02-28 | Ranbaxy Laboratories Limited | Acides carboxyliques a substitution beta-hydroxy et amino en tant qu'inhibiteurs de la metalloprotease matricielle |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3649651A (en) * | 1969-07-02 | 1972-03-14 | American Home Prod | Dibenzofuran derivatives and preparation thereof |
| US5326760A (en) * | 1992-06-29 | 1994-07-05 | Glaxo, Inc. | Aminobutanoic acid compounds having metalloprotease inhibiting properties |
-
1996
- 1996-04-26 KR KR1019970708650A patent/KR19990022171A/ko not_active Application Discontinuation
- 1996-04-26 AT AT96913185T patent/ATE206416T1/de not_active IP Right Cessation
- 1996-04-26 EP EP96913185A patent/EP0828726B1/fr not_active Expired - Lifetime
- 1996-04-26 PT PT96913185T patent/PT828726E/pt unknown
- 1996-04-26 CA CA002220040A patent/CA2220040A1/fr not_active Abandoned
- 1996-04-26 AU AU55777/96A patent/AU717570B2/en not_active Ceased
- 1996-04-26 WO PCT/US1996/005830 patent/WO1996038434A1/fr not_active Application Discontinuation
- 1996-04-26 ES ES96913185T patent/ES2165496T3/es not_active Expired - Lifetime
- 1996-04-26 MX MX9708728A patent/MX9708728A/es not_active IP Right Cessation
- 1996-04-26 DK DK96913185T patent/DK0828726T3/da active
- 1996-04-26 JP JP8536475A patent/JPH11506097A/ja not_active Abandoned
- 1996-04-26 DE DE69615680T patent/DE69615680T2/de not_active Expired - Fee Related
- 1996-05-31 ZA ZA964508A patent/ZA964508B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2165496T3 (es) | 2002-03-16 |
| PT828726E (pt) | 2002-03-28 |
| AU5577796A (en) | 1996-12-18 |
| AU717570B2 (en) | 2000-03-30 |
| DE69615680T2 (de) | 2002-07-11 |
| JPH11506097A (ja) | 1999-06-02 |
| EP0828726A1 (fr) | 1998-03-18 |
| WO1996038434A1 (fr) | 1996-12-05 |
| EP0828726B1 (fr) | 2001-10-04 |
| MX9708728A (es) | 1997-12-31 |
| ZA964508B (en) | 1996-12-09 |
| CA2220040A1 (fr) | 1996-12-05 |
| ATE206416T1 (de) | 2001-10-15 |
| KR19990022171A (ko) | 1999-03-25 |
| DE69615680D1 (de) | 2001-11-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL123901A (en) | Sulfonamide inhibitors of matrix metalloproteinases and pharmaceutical compositions comprising them | |
| DK0828726T3 (da) | Tricykliske inhibitorer af matrixmetalloproteinaser | |
| ATE277929T1 (de) | Immunsuppressive wirkungen von pteridinderivaten | |
| DE69619865T2 (de) | Aromatische keto-säure und ihre derivate als inhibitoren der matrix metalloproteinase | |
| HN1997000052A (es) | Nuevas 4(3h)--quinazolinas 2,3-disustituidas | |
| AP2001002037A0 (en) | Tricyclic sulfonamides and their derivatives as inhibitors of matrix metalloproteinases. | |
| FI953139A (fi) | Atovakonia käsittäviä farmaseuttisia koostumuksia | |
| DK0642351T3 (da) | Nye farmaceutiske anvendelser af krillenzymer | |
| WO2001012592A3 (fr) | Composes d'acide hydroxamique utiles comme inhibiteurs de metalloproteinases matricielles | |
| NO20000771D0 (no) | Anvendelse av fankinon for behandling av Alzheimers sykdom | |
| ATE330604T1 (de) | Behandlung von manischen erkrankungen | |
| CA2233560A1 (fr) | Inhibiteurs de metalloprotineases matricielles a base de sulfamide | |
| EA199700451A1 (ru) | Мономерные 4,4-(дизамещенные) циклогексан-1-олы и родственные соединения | |
| EA200000006A1 (ru) | Новые производные пентаэритрита, их получение и применение, а также промежуточные соединения для их синтеза |