ATE206416T1 - Trizyklische verbindungen als matrix- metalloproteinase inhibitoren - Google Patents
Trizyklische verbindungen als matrix- metalloproteinase inhibitorenInfo
- Publication number
- ATE206416T1 ATE206416T1 AT96913185T AT96913185T ATE206416T1 AT E206416 T1 ATE206416 T1 AT E206416T1 AT 96913185 T AT96913185 T AT 96913185T AT 96913185 T AT96913185 T AT 96913185T AT E206416 T1 ATE206416 T1 AT E206416T1
- Authority
- AT
- Austria
- Prior art keywords
- tricyclic compounds
- matrix metalloproteinase
- metalloproteinase inhibitors
- gelatinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/460,436 US5665764A (en) | 1995-06-02 | 1995-06-02 | Tricyclic inhibitors of matrix metalloproteinases |
| US08/460,437 US5627206A (en) | 1995-06-02 | 1995-06-02 | Tricyclic inhibitor of matrix metalloproteinases |
| PCT/US1996/005830 WO1996038434A1 (en) | 1995-06-02 | 1996-04-26 | Tricyclic inhibitors of matrix metalloproteinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE206416T1 true ATE206416T1 (de) | 2001-10-15 |
Family
ID=27039692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96913185T ATE206416T1 (de) | 1995-06-02 | 1996-04-26 | Trizyklische verbindungen als matrix- metalloproteinase inhibitoren |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0828726B1 (de) |
| JP (1) | JPH11506097A (de) |
| KR (1) | KR19990022171A (de) |
| AT (1) | ATE206416T1 (de) |
| AU (1) | AU717570B2 (de) |
| CA (1) | CA2220040A1 (de) |
| DE (1) | DE69615680T2 (de) |
| DK (1) | DK0828726T3 (de) |
| ES (1) | ES2165496T3 (de) |
| MX (1) | MX9708728A (de) |
| PT (1) | PT828726E (de) |
| WO (1) | WO1996038434A1 (de) |
| ZA (1) | ZA964508B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9711988A (pt) * | 1996-09-04 | 1999-08-24 | Warner Lambert Co | Inibidores de metaloproteinase de matriz e seus empregos terap-uticos |
| US6624177B1 (en) | 1996-09-04 | 2003-09-23 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
| BR9712794A (pt) | 1996-09-04 | 1999-12-14 | Warner Lambert Co | Compostos para e um método de inibição de metaloproteinases matriciais |
| MXPA99001974A (es) * | 1996-12-09 | 2002-03-27 | Warner Lambert Co | Metodo para tratar y prevenir fallas cardiacas y dilatacion ventricular. |
| SI0946166T1 (en) * | 1996-12-17 | 2004-06-30 | Warner-Lambert Company Llc | Use of matrix metalloproteinase inhibitors for promoting wound healing |
| JP2001507342A (ja) * | 1996-12-17 | 2001-06-05 | ワーナー−ランバート・コンパニー | 神経疾患の治療および創傷治癒を促進するためのマトリックスメタロプロテイナーゼ阻害剤の使用 |
| US6399612B1 (en) | 1997-10-06 | 2002-06-04 | Warner-Lambert Company | Heteroaryl butyric acids and their derivatives as inhibitors of matrix metalloproteinases |
| AU4229499A (en) | 1998-07-30 | 2000-02-21 | Warner-Lambert Company | Tricyclic heteroaromatics and their derivatives as inhibitors of matrix metalloproteinases |
| JP2002521478A (ja) | 1998-07-30 | 2002-07-16 | ワーナー−ランバート・カンパニー | マトリックスメタロプロテイナーゼの阻害剤としての３環式スルホンアミド及びそれらの誘導体 |
| DOP2002000334A (es) * | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Pirimidinas biciclicas como inhibidores de metaloproteinasas de matriz |
| WO2004014880A1 (en) * | 2002-08-13 | 2004-02-19 | Warner-Lambert Company Llc | Chromone derivatives as matrix metalloproteinase inhibitors |
| CA2661299A1 (en) * | 2006-08-22 | 2008-02-28 | Ranbaxy Laboratories Limited | Beta -hydroxy-and amino-substituted carboxylic acids as matrix metalloproteinase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3649651A (en) * | 1969-07-02 | 1972-03-14 | American Home Prod | Dibenzofuran derivatives and preparation thereof |
| US5326760A (en) * | 1992-06-29 | 1994-07-05 | Glaxo, Inc. | Aminobutanoic acid compounds having metalloprotease inhibiting properties |
-
1996
- 1996-04-26 KR KR1019970708650A patent/KR19990022171A/ko not_active Application Discontinuation
- 1996-04-26 AT AT96913185T patent/ATE206416T1/de not_active IP Right Cessation
- 1996-04-26 EP EP96913185A patent/EP0828726B1/de not_active Expired - Lifetime
- 1996-04-26 PT PT96913185T patent/PT828726E/pt unknown
- 1996-04-26 CA CA002220040A patent/CA2220040A1/en not_active Abandoned
- 1996-04-26 AU AU55777/96A patent/AU717570B2/en not_active Ceased
- 1996-04-26 WO PCT/US1996/005830 patent/WO1996038434A1/en not_active Application Discontinuation
- 1996-04-26 ES ES96913185T patent/ES2165496T3/es not_active Expired - Lifetime
- 1996-04-26 MX MX9708728A patent/MX9708728A/es not_active IP Right Cessation
- 1996-04-26 DK DK96913185T patent/DK0828726T3/da active
- 1996-04-26 JP JP8536475A patent/JPH11506097A/ja not_active Abandoned
- 1996-04-26 DE DE69615680T patent/DE69615680T2/de not_active Expired - Fee Related
- 1996-05-31 ZA ZA964508A patent/ZA964508B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2165496T3 (es) | 2002-03-16 |
| PT828726E (pt) | 2002-03-28 |
| AU5577796A (en) | 1996-12-18 |
| AU717570B2 (en) | 2000-03-30 |
| DE69615680T2 (de) | 2002-07-11 |
| JPH11506097A (ja) | 1999-06-02 |
| EP0828726A1 (de) | 1998-03-18 |
| WO1996038434A1 (en) | 1996-12-05 |
| EP0828726B1 (de) | 2001-10-04 |
| DK0828726T3 (da) | 2002-01-21 |
| MX9708728A (es) | 1997-12-31 |
| ZA964508B (en) | 1996-12-09 |
| CA2220040A1 (en) | 1996-12-05 |
| KR19990022171A (ko) | 1999-03-25 |
| DE69615680D1 (de) | 2001-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |