DK0817622T3 - Transdermalt applicerbart lægemiddel med ACE-hæmmere - Google Patents

Transdermalt applicerbart lægemiddel med ACE-hæmmere

Info

Publication number
DK0817622T3
DK0817622T3 DK96911973T DK96911973T DK0817622T3 DK 0817622 T3 DK0817622 T3 DK 0817622T3 DK 96911973 T DK96911973 T DK 96911973T DK 96911973 T DK96911973 T DK 96911973T DK 0817622 T3 DK0817622 T3 DK 0817622T3
Authority
DK
Denmark
Prior art keywords
ace inhibitors
applicable drug
transdermally applicable
transdermally
drug
Prior art date
Application number
DK96911973T
Other languages
English (en)
Inventor
Wilfried Fischer
Karin Klokkers
Anna Sendl-Lang
Original Assignee
Hexal Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexal Ag filed Critical Hexal Ag
Application granted granted Critical
Publication of DK0817622T3 publication Critical patent/DK0817622T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK96911973T 1995-03-31 1996-03-29 Transdermalt applicerbart lægemiddel med ACE-hæmmere DK0817622T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19512181A DE19512181C2 (de) 1995-03-31 1995-03-31 Transdermales System mit Ramipril und/oder Trandolapril als ACE-Hemmer
PCT/EP1996/001402 WO1996029999A1 (de) 1995-03-31 1996-03-29 Transdermal applizierbares arzneimittel mit ace-hemmern

Publications (1)

Publication Number Publication Date
DK0817622T3 true DK0817622T3 (da) 2002-03-25

Family

ID=7758491

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96911973T DK0817622T3 (da) 1995-03-31 1996-03-29 Transdermalt applicerbart lægemiddel med ACE-hæmmere

Country Status (19)

Country Link
US (1) US6303141B1 (da)
EP (1) EP0817622B1 (da)
JP (1) JP3924008B2 (da)
AT (1) ATE209482T1 (da)
AU (1) AU700418B2 (da)
BR (1) BR9607872A (da)
CA (1) CA2216278A1 (da)
CZ (1) CZ287373B6 (da)
DE (2) DE19512181C2 (da)
DK (1) DK0817622T3 (da)
ES (1) ES2167558T3 (da)
HU (1) HUP9801989A3 (da)
NO (1) NO974508L (da)
NZ (1) NZ306429A (da)
PL (1) PL322576A1 (da)
PT (1) PT817622E (da)
SK (1) SK125897A3 (da)
WO (1) WO1996029999A1 (da)
ZA (1) ZA962592B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
DE19820151A1 (de) * 1998-05-06 1999-11-11 Hexal Ag Transdermales therapeutisches System zur Anwendung von Candesartan
EE200100342A (xx) 1998-12-23 2002-10-15 Idea Ag Parendatud ravimvorm in vivo mitteinvasiivseks paikseks rakendamiseks
EP1031346B1 (en) 1999-01-27 2002-05-02 Idea Ag Noninvasive vaccination through the skin
ES2173679T3 (es) 1999-01-27 2002-10-16 Idea Ag Inmunizacion/transporte transnasal con vehiculos altamente adaptables.
MXPA02000053A (es) * 1999-07-05 2003-07-21 Idea Ag Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
DE10033855A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Matrixkontrolliertes transdermales System mit Sulfonsäuresalz eines ACE-Hemmers
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
RU2358699C2 (ru) * 2001-06-18 2009-06-20 Ноувен Фамэсьютикэлз, Инк. Композиция для чрескожной доставки лекарственного средства (варианты), способ ее получения и использование
US6805878B2 (en) 2001-09-13 2004-10-19 Noven Pharmaceuticals, Inc. Transdermal administration of ACE inhibitors
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
KR20070086045A (ko) * 2004-11-12 2007-08-27 이데아 아게 피부 상태 치료에서의 확대된 표면 집합체
WO2006100154A1 (en) 2005-03-24 2006-09-28 Nolabs Ab Cosmetic treatment with nitric oxide, device for performing said treatment and manufacturing method therefor
EP1704876A1 (en) * 2005-03-24 2006-09-27 NOLabs AB Cosmetic treatment, device for performing said treatment and manufacturing method thereof
JP5058531B2 (ja) 2005-09-09 2012-10-24 日東電工株式会社 ビソプロロール含有貼付製剤
DE102005058166A1 (de) 2005-12-05 2007-06-06 Hexal Ag Matrixkontrolliertes transdermales System mit Amin-Salzen der ACE-Hemmer-Dicarbonsäuren
JP4945228B2 (ja) * 2005-12-13 2012-06-06 日東電工株式会社 ビソプロロール含有貼付製剤
JP5015562B2 (ja) * 2005-12-13 2012-08-29 日東電工株式会社 貼付製剤
US7943655B2 (en) * 2006-04-05 2011-05-17 Universitat Zurich Polymorphic and pseudopolymorphic forms of trandolaprilat, pharmaceutical compositions and methods for production and use
KR20090118957A (ko) 2007-03-08 2009-11-18 닛토덴코 가부시키가이샤 비소프롤롤 경피 투여 디바이스
EP2729131B1 (en) 2011-07-05 2020-04-15 Novan, Inc. Topical compositions
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
US11813284B2 (en) 2013-08-08 2023-11-14 Novan, Inc. Topical compositions and methods of using the same
EP3177262A4 (en) 2014-08-08 2018-04-18 Novan Inc. Topical emulsions
US10912743B2 (en) 2016-03-02 2021-02-09 Novan, Inc. Compositions for treating inflammation and methods of treating the same
BR112018070578A2 (pt) 2016-04-13 2019-02-12 Novan, Inc. composições, sistemas, kits, e métodos para tratar uma infecção

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256687A (en) * 1985-09-09 1993-10-26 Hoechst Aktiengesellschaft Pharmaceutical composition for the treatment of high blood pressure
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4898732A (en) * 1988-05-04 1990-02-06 The Clinipad Corporation Inhibiting of tumor growth with an antagonist of the renin-angioten-sin system
JPH0774116B2 (ja) * 1989-10-05 1995-08-09 信越半導体株式会社 Ｓｉ単結晶中の酸素濃度調整方法およびその装置
US5269875A (en) 1989-10-05 1993-12-14 Shin-Etsu Handotai Company, Limited Method of adjusting concentration of oxygen in silicon single crystal and apparatus for use in the method
US5073539A (en) * 1990-01-22 1991-12-17 Ciba-Geigy Corporation Transdermal administration of zwitterionic drugs
JP2849937B2 (ja) 1990-04-18 1999-01-27 日東電工株式会社 医療用貼付剤
FR2664815B1 (fr) * 1990-07-23 1994-11-04 Adir Systeme matriciel autoadhesif pour la liberation prolongee du piribedil par voie transcutanee.
US5464387A (en) * 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
WO1993023019A1 (en) * 1992-05-11 1993-11-25 Sri International Transdermal drug delivery systems and related compositions and methods of use

Also Published As

Publication number Publication date
DE59608323D1 (de) 2002-01-10
AU5498296A (en) 1996-10-16
PT817622E (pt) 2002-05-31
HUP9801989A3 (en) 2000-06-28
DE19512181C2 (de) 2003-11-06
US6303141B1 (en) 2001-10-16
NO974508L (no) 1997-10-27
EP0817622A1 (de) 1998-01-14
PL322576A1 (en) 1998-02-02
ATE209482T1 (de) 2001-12-15
CA2216278A1 (en) 1996-10-03
HUP9801989A2 (hu) 1999-02-01
AU700418B2 (en) 1999-01-07
CZ287373B6 (en) 2000-11-15
EP0817622B1 (de) 2001-11-28
JPH11502827A (ja) 1999-03-09
CZ302897A3 (cs) 1998-02-18
ZA962592B (en) 1997-10-01
NZ306429A (en) 2000-07-28
MX9707507A (es) 1997-11-29
WO1996029999A1 (de) 1996-10-03
NO974508D0 (no) 1997-09-29
DE19512181A1 (de) 1996-10-02
JP3924008B2 (ja) 2007-06-06
ES2167558T3 (es) 2002-05-16
SK125897A3 (en) 1998-02-04
BR9607872A (pt) 1999-11-30

Similar Documents

Publication Publication Date Title
DK0817622T3 (da) Transdermalt applicerbart lægemiddel med ACE-hæmmere
FI962315A0 (fi) Entsyymi-inhibiittorit
DK125696A (da) Inhibitorer for rotamase enzymaktivitet
DE122004000046I1 (de) Medikamenten-Vorstufen f}r Thrombin-Inhibitoren.
DE69815090D1 (de) Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen
NO974213L (no) Små-molekylære inhibitorer for rotamase-enzym-aktivitet
ES2106888T3 (es) Sistemas terapeuticos transdermicos con inhibidores de la cristalizacion.
ES2144019T3 (es) Composicion farmaceutica que contiene inhibidores de glucosidasa y/o de amilasa, y un inhibidor de lipasa.
BR9908280A (pt) Inibidores de enzimas de fosfolipase
ATE230393T1 (de) Ace-inhibitoren stickstoffsalze
TR199600716A2 (tr) Siklik yapistirici inhibitörleri.
MX9300777A (es) Derivados aminoacetilmercapto novedosos utiles como inhibidores de la encefalinasa y la eca
FI973282A (fi) Trombiinin inhibiittoreita
DK0840606T3 (da) Små di- og trivalente molekyler som selectininhibitorer
ATE239755T1 (de) Thrombin inhibitoren
DE68904083D1 (de) Hmg-coa-reduktaseinhibitoren.
DE68901091D1 (de) Hmg-coa-reduktaseinhibitoren.
DK0825857T3 (da) Anvendelse af gabapentin og derivater deraf til behandling af mani og bipolær lidelse
EE9800044A (et) Prolüülendopeptidaasi inhibiitorid
ES2186807T3 (es) Inhibidores de trombina.
FI881972A0 (fi) Anvaendning av en ace-inhibitor foer inhibitering av foerlusten av kognitiva funktioner.
FI913645A0 (fi) Transdermalt system med vilket farmakologiskt aktiva foereningar appliseras i effekt-kontrollerade faorhaollanden.
SI0817622T1 (en) Medicament with angiotensin converting enzyme (ace) inhibitors suitable for transdermal application