DK0807431T3 - Fremgangsmåde til fremstilling af carotenoidpræparater - Google Patents

Fremgangsmåde til fremstilling af carotenoidpræparater

Info

Publication number
DK0807431T3
DK0807431T3 DK97106957T DK97106957T DK0807431T3 DK 0807431 T3 DK0807431 T3 DK 0807431T3 DK 97106957 T DK97106957 T DK 97106957T DK 97106957 T DK97106957 T DK 97106957T DK 0807431 T3 DK0807431 T3 DK 0807431T3
Authority
DK
Denmark
Prior art keywords
carotenoid
preparation
carotenoid preparations
disclosed
emulsion
Prior art date
Application number
DK97106957T
Other languages
Danish (da)
English (en)
Inventor
Leonard Joseph Scialpi
Ray Edward Kowalski
William Joseph Mergens
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of DK0807431T3 publication Critical patent/DK0807431T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924Significant dispersive or manipulative operation or step in making or stabilizing colloid system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK97106957T 1996-05-14 1997-04-26 Fremgangsmåde til fremstilling af carotenoidpræparater DK0807431T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1756896P 1996-05-14 1996-05-14

Publications (1)

Publication Number Publication Date
DK0807431T3 true DK0807431T3 (da) 2004-07-26

Family

ID=21783319

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97106957T DK0807431T3 (da) 1996-05-14 1997-04-26 Fremgangsmåde til fremstilling af carotenoidpræparater

Country Status (10)

Country Link
US (1) US6093348A (cs)
EP (1) EP0807431B1 (cs)
JP (1) JP3961070B2 (cs)
CN (1) CN1079212C (cs)
AT (1) ATE262316T1 (cs)
BR (1) BR9703134A (cs)
DE (1) DE69728206T2 (cs)
DK (1) DK0807431T3 (cs)
ES (1) ES2216079T3 (cs)
IN (1) IN183685B (cs)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3176934B2 (ja) * 1996-01-22 2001-06-18 セーホーエル.ハンセン アクティーゼルスカブ 疎水性天然色素を含む水分散性配合物、その製造方法および使用
EE05190B1 (et) 1998-11-20 2009-08-17 Rtp Pharma Inc. Dispergeeruvad fosfolipiididega stabiliseeritud mikroosakesed
HK1053786A1 (zh) * 2000-04-20 2003-11-07 Rtp Pharma Inc. 改进的水不溶的药物颗粒工艺
US20030104090A1 (en) * 2000-05-05 2003-06-05 Levy Pedro E. Supplements containing annatto extracts and carotenoids and methods for using the same
AU2001262945B2 (en) 2000-09-20 2006-02-02 Skyepharma Canada Inc. Spray drying process and compositions of fenofibrate
DE10064387A1 (de) * 2000-12-21 2002-06-27 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Sauerstoff-haltiger Carotinoide
JPWO2002077105A1 (ja) * 2001-03-22 2004-07-15 富士化学工業株式会社 安定なアスタキサンチン含有粉体組成物及びその製造方法
US6811801B2 (en) * 2001-12-12 2004-11-02 Abbott Laboratories Methods and compositions for brightening the color of thermally processed nutritionals
EP2823809B1 (en) 2002-06-28 2016-11-02 Protiva Biotherapeutics Inc. Method and apparatus for producing liposomes
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
CN101845009B (zh) 2002-07-29 2012-10-03 卡达克斯药物公司 用于抑制和改善疾病的类胡萝卜素结构类似物
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
US7723327B2 (en) 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
US20050059635A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling C-reactive protein levels
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US7763649B2 (en) 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
JP4773337B2 (ja) * 2003-03-27 2011-09-14 ディーエスエム アイピー アセッツ ビー.ブイ. ビーズレットの製造方法
US7332178B2 (en) 2003-04-25 2008-02-19 Abbott Laboratories Stable nutritional powder containing ascorbyl palmitate
US7110827B2 (en) * 2003-04-25 2006-09-19 Medtronic, Inc. Electrical connectors for medical lead having weld-less wiring connection
US9247765B2 (en) * 2004-01-14 2016-02-02 Omniactive Health Technologies Limited Stable beadlets of lipophilic nutrients
WO2005102356A1 (en) * 2004-04-14 2005-11-03 Hawaii Biotech, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
JP4562174B2 (ja) * 2004-08-23 2010-10-13 カゴメ株式会社 カロテノイド含有物の製造方法
MX2007002374A (es) * 2004-08-31 2007-04-23 Akzo Nobel Nv Metodo de solubilizacion de pigmento, una composicion de pigmento y su uso.
US10463061B2 (en) * 2004-11-19 2019-11-05 Dsm Ip Assets B.V. Modified plant gums for preparations of active ingredients
US8755258B2 (en) 2005-02-16 2014-06-17 Mitsubishi Electric Corporation Optical disc and optical disc device
CN100421650C (zh) * 2005-03-23 2008-10-01 浙江新和成股份有限公司 水分散性类胡萝卜素粉的制备方法
AU2006274413B2 (en) * 2005-07-27 2013-01-10 Arbutus Biopharma Corporation Systems and methods for manufacturing liposomes
ES2420155T3 (es) * 2005-08-15 2013-08-22 Phares Drug Delivery Ag Formas de cristal de astaxantina
US7435846B2 (en) * 2006-08-18 2008-10-14 Industrial Organica, S.A. De C.V. Absorption and bioavailability of carotenoids, formulations and applications
CA2677897A1 (en) * 2007-03-15 2008-09-18 Dsm Ip Assets B.V. Stabilized micronised particles
WO2009093595A1 (ja) * 2008-01-25 2009-07-30 Fujifilm Corporation カロテノイド含有エマルション組成物の製造方法、それにより得られるカロテノイド含有エマルション組成物並びにカロテノイド含有粉末組成物、該組成物を含む機能性食品及び化粧品
EP2210593A3 (en) 2009-01-21 2011-05-18 DSM IP Assets B.V. Tablettable formulations of vitamin A and derivatives thereof
US9724664B2 (en) 2009-03-27 2017-08-08 Bend Research, Inc. Spray-drying process
JP5574266B2 (ja) * 2009-09-14 2014-08-20 国立大学法人北海道大学 抗植物ウイルス剤
CN102933098B (zh) 2010-06-08 2017-03-29 三荣源有限公司 防止类胡萝卜色素附着于容器的方法
JP5600513B2 (ja) * 2010-07-29 2014-10-01 理研ビタミン株式会社 クロセチン製剤の製造方法
WO2012031133A2 (en) 2010-09-03 2012-03-08 Bench Research, Inc. Spray-drying apparatus and methods of using the same
US9084976B2 (en) 2010-09-03 2015-07-21 Bend Research, Inc. Spray-drying apparatus and methods of using the same
WO2012040502A1 (en) 2010-09-24 2012-03-29 Bend Research, Inc. High-temperature spray drying process and apparatus
CN103327827B (zh) * 2010-11-26 2016-02-10 帝斯曼知识产权资产管理有限公司 用于活性成分的保护性水胶体
US20120157547A1 (en) 2010-12-21 2012-06-21 Ricardo Montoya-Olvera Compositions and applications of carotenoids of improved absorption and bioavailability
CN104736229B (zh) * 2012-10-18 2017-05-03 帝斯曼知识产权资产管理有限公司 包含类胡萝卜素的珠粒
WO2015044222A1 (en) * 2013-09-24 2015-04-02 Dsm Ip Assets B.V. Stable formulations for coloring beverages and food products
CA2962719A1 (en) 2014-10-31 2016-05-06 Bend Research Inc. Process for forming active domains dispersed in a matrix
US11744266B2 (en) 2016-03-15 2023-09-05 Dsm Ip Assets B.V. Coated particles
EP3432730B1 (de) * 2016-03-24 2023-11-08 Basf Se Mehrphasige wirkstoffzubereitungen
JP7171542B2 (ja) * 2016-07-19 2022-11-15 ビーエーエスエフ ソシエタス・ヨーロピア 没食子酸プロピル含有ビタミン製剤
US11197493B2 (en) * 2017-09-12 2021-12-14 Omniactive Health Technologies Limited Stabilized fat soluble nutrient compositions and process for the preparation thereof
JP7225820B2 (ja) 2019-01-21 2023-02-21 株式会社アイシン 車両用開閉体制御装置
WO2020254409A1 (en) * 2019-06-17 2020-12-24 Dsm Ip Assets B.V. Composition comprising metformin hci, vitamin b12 and at least one flow additive
KR20220024544A (ko) * 2019-06-17 2022-03-03 디에스엠 아이피 어셋츠 비.브이. 메트포르민 및 칼슘 시트레이트를 포함하는 약학적 투여 형태
WO2020254396A1 (en) * 2019-06-17 2020-12-24 Dsm Ip Assets B.V. Solid pharmaceutical dosage form comprising spray dried vitamin b12
CN112438950A (zh) * 2019-08-16 2021-03-05 北京化工大学 一种β-胡萝卜素透明水分散液及其制备方法
CN111471317B (zh) * 2020-03-26 2021-06-04 广东省农业科学院蚕业与农产品加工研究所 一种稳态化玉米黄色素及其制备方法
CN111838648B (zh) * 2020-06-16 2023-04-25 嘉必优生物技术(武汉)股份有限公司 一种生产纳米级类胡萝卜素乳液的装置及方法
CA3189338A1 (en) 2020-07-16 2022-01-20 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles
CN112841645A (zh) * 2021-01-14 2021-05-28 江南大学 一种β-胡萝卜素微胶囊的制备方法
CN113426355A (zh) * 2021-06-25 2021-09-24 骏马化纤股份有限公司 一种化纤生产用油剂乳液自动化控制系统及制备方法
WO2023114943A2 (en) 2021-12-16 2023-06-22 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
CN118525919A (zh) * 2023-02-22 2024-08-23 浙江可明生物医药有限公司 类胡萝卜素制剂的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2756177A (en) * 1953-03-09 1956-07-24 Hoffmann La Roche Process for making fat-soluble vitamin active powder
US2861891A (en) * 1956-12-13 1958-11-25 Hoffmann La Roche Water dispersible carotenoid compositions and process of making the same
DE1211911B (de) * 1959-09-08 1966-03-03 Hoffmann La Roche Verfahren zur Herstellung eines insbesondere zum Faerben von Lebens- und Futtermitteln geeigneten Carotinoidpraeparates
US3998753A (en) * 1974-08-13 1976-12-21 Hoffmann-La Roche Inc. Water dispersible carotenoid preparations and processes thereof
DE3048000A1 (de) * 1980-12-19 1982-07-15 Basf Ag Stabile injizierbare (beta)-carotin-solubilisate und verfahren zu ihrer herstellung
US4908154A (en) * 1981-04-17 1990-03-13 Biotechnology Development Corporation Method of forming a microemulsion
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
DE3119383A1 (de) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten
SE8604117D0 (sv) * 1986-09-29 1986-09-29 Kabivitrum Ab Composition
DE3702031A1 (de) * 1987-01-24 1988-08-04 Basf Ag Verfahren zur herstellung von mikrodispersen fischoelpraeparaten
ATE96312T1 (de) * 1989-07-25 1993-11-15 Hoffmann La Roche Verfahren zur herstellung von carotinoidpraeparaten.
DK546289D0 (da) * 1989-11-02 1989-11-02 Danochemo As Carotenoidpulvere
DK19393D0 (da) * 1993-02-19 1993-02-19 Danochemo As Fremgangsmaade til fremstilling af et i vand dispergerbart pulverformigt carotenoidpraeparat
DE4329446A1 (de) * 1993-09-01 1995-03-02 Basf Ag Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen
DE19649062A1 (de) * 1996-11-27 1998-05-28 Basf Ag Flüssige, mit Öl mischbare Carotinoid-Zubereitungen

Also Published As

Publication number Publication date
CN1176760A (zh) 1998-03-25
ES2216079T3 (es) 2004-10-16
EP0807431B1 (en) 2004-03-24
IN183685B (cs) 2000-03-18
BR9703134A (pt) 1998-08-18
EP0807431A3 (en) 1998-08-12
JP3961070B2 (ja) 2007-08-15
ATE262316T1 (de) 2004-04-15
US6093348A (en) 2000-07-25
DE69728206D1 (de) 2004-04-29
EP0807431A2 (en) 1997-11-19
JPH1046041A (ja) 1998-02-17
DE69728206T2 (de) 2005-03-10
CN1079212C (zh) 2002-02-20

Similar Documents

Publication Publication Date Title
DK0807431T3 (da) Fremgangsmåde til fremstilling af carotenoidpræparater
DK0805822T4 (da) Spraytørret erythropoietin
HUT54895A (en) Process for producing stabilized fgf composition
DE69717263D1 (de) Zubereitung mit verzögerter freisetzung und deren herstellung
AU2741295A (en) Method for preparing an influenza virus, antigens obtained and applications thereof
ES2066491T3 (es) Composiciones de colorantes en polvo y procedimiento para su preparacion.
NO974768D0 (no) Fremgangsmåte for fremstilling av et forbedret lavtstövende, lettflytende pigment
EP0837139A3 (en) Two step conversion of vegetable protein isoflavone conjugates to isoflavone aglucones
AU2808295A (en) Aqueous fluoropolymer emulsion and process for producing the same
EP0755440A4 (en) NOVEL MUT VIRUSES, ANTIVIRAL COMPOUNDS, AND NOVEL VACCINE PRODUCTION METHODS
EP1044617A3 (de) Verfahren zur Herstellung fixierbarer Einlagestoffe
BR9000736A (pt) Processo para preparar uma composicao aquosa para xampu
DK0566645T3 (da) Fremgangsmåde til fremstilling af et vegetabilsk proteinhydrolysat
ES2196743T3 (es) Sorbitol en polvo y su procedimiento de preparacion.
DK559887A (da) Fremgangsmaade til fremstilling af carbinolderivater
CA2085114A1 (en) Method for preparation of colored porous polytetrafluorethylene material
GB2363360B (en) A method of shaping heat-shrinkable materials
HU186343B (en) Pungicide preparations containing 2,3,6-trisubsituted-n-acyl-anilide derivatives as actor as well as method for producing the actors
DE3881326D1 (de) Verfahren zur herstellung von paramunitaetsinducern.
NO302370B1 (no) Fremgangsmåte for fremstilling av en vandig emulsjon med snever dråpestörrelsesfordeling, og anvendelse av en slik emulsjon for fremstilling av en polymerdispersjon
AU5266790A (en) Hydraulic substance, method of producing and curing the same, curing chamber, and paint
GB8618114D0 (en) Joining of pipes
AU2484488A (en) Method for the production of antigenic protein-hapten conjugates, and antibodies corresponding thereto
AU7408591A (en) Plasticizing resins, aqueous dispersions thereof and methods of making the same
ATA251486A (de) Verfahren zur herstellung von neuen loeslichen und/oder schmelzbaren polyamidimid-polyimidblockcopolymeren