DK0807185T3 - Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcus - Google Patents
Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcusInfo
- Publication number
- DK0807185T3 DK0807185T3 DK96902922T DK96902922T DK0807185T3 DK 0807185 T3 DK0807185 T3 DK 0807185T3 DK 96902922 T DK96902922 T DK 96902922T DK 96902922 T DK96902922 T DK 96902922T DK 0807185 T3 DK0807185 T3 DK 0807185T3
- Authority
- DK
- Denmark
- Prior art keywords
- new
- lta
- streptococcus
- lipoteichoic acid
- grop
- Prior art date
Links
- 241000194017 Streptococcus Species 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol Substances OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical compound C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 1
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 1
- 108010003272 Hyaluronate lyase Proteins 0.000 abstract 1
- 102000001974 Hyaluronidases Human genes 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000007857 degradation product Substances 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 125000003128 glycerophosphate group Chemical group 0.000 abstract 1
- 229960002773 hyaluronidase Drugs 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/51—Lyases (4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95101208 | 1995-01-30 | ||
| PCT/EP1996/000309 WO1996023896A1 (en) | 1995-01-30 | 1996-01-24 | Antitumor and anticholesterol preparations containing a lipoteichoic acid from steptococcus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0807185T3 true DK0807185T3 (da) | 2002-10-07 |
Family
ID=8218940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96902922T DK0807185T3 (da) | 1995-01-30 | 1996-01-24 | Antitumorpræparater indeholdende en lipoteichoinsyre fra streptococcus |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6114161A (da) |
| EP (1) | EP0807185B9 (da) |
| JP (1) | JP3638955B2 (da) |
| CN (1) | CN1113102C (da) |
| AT (1) | ATE219146T1 (da) |
| AU (1) | AU4714196A (da) |
| CA (1) | CA2208780C (da) |
| DE (1) | DE69621776T2 (da) |
| DK (1) | DK0807185T3 (da) |
| ES (1) | ES2178699T3 (da) |
| WO (1) | WO1996023896A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113102C (zh) * | 1995-01-30 | 2003-07-02 | 彼得·特鲁格 | 抗肿瘤制剂 |
| US6610293B1 (en) | 1997-06-16 | 2003-08-26 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria |
| DE19728900A1 (de) * | 1997-07-07 | 1999-01-14 | Henkel Kgaa | Hydrophile Glykoside |
| EP1832662B1 (en) * | 1998-04-02 | 2011-03-09 | The Board Of Regents Of The University Of Oklahoma | DNA encoding chondroitin synthase from Pasteurella multocida and methods of use |
| ATE543509T1 (de) | 2001-08-13 | 2012-02-15 | Univ Florida | Material und verfahren zur förderung der reparatur von nervengewebe |
| AU2003220115A1 (en) * | 2002-05-20 | 2003-12-12 | Board Of Regents, The University Of Texas System | Methods and compositions for delivering enzymes and nucleic acid molecules to brain, bone, and other tissues |
| KR100443080B1 (ko) * | 2002-07-11 | 2004-08-04 | 일동제약주식회사 | 콜레스테롤 저하능을 갖는 스트렙토코커스 페시움 균주 |
| EP1567868A4 (en) * | 2002-12-02 | 2008-02-06 | Biosynexus Inc | CELL WALL TEICHONSURE AS A GOAL F RANTI-STAPHYLOCOCCUS THERAPIES AND VACCINATES |
| GB0717442D0 (en) * | 2007-09-07 | 2007-10-17 | Isis Innovation | Compositions and uses thereof |
| SI2454284T1 (en) | 2009-07-15 | 2018-07-31 | Aimm Therapeutics B.V. | Compounds that specifically bind to Gram-positive bacteria |
| WO2011025286A2 (ko) * | 2009-08-26 | 2011-03-03 | 주식회사 알엔에이 | 리포테이코익산 유래 당지질 및 이를 포함하는 조성물 |
| EP2380565A1 (en) | 2010-03-31 | 2011-10-26 | Lunamed AG | Compositions for dental treatment comprising Lipoteichoic acids or parts thereof like mono- or polyglycerphosphates |
| EP2500349B1 (en) * | 2011-03-11 | 2015-05-06 | Universitätsklinikum Freiburg | Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections |
| EP2545909A1 (en) | 2011-07-12 | 2013-01-16 | Lunamed AG | Combination of D-Amino Acids and Lipoteichoic Acid |
| EP2545911A1 (en) | 2011-07-12 | 2013-01-16 | Lunamed AG | Use of Lipoteichoic Acid in the Treatment of Non-Encapsulated Cancer Cells |
| EP2545910A1 (en) | 2011-07-12 | 2013-01-16 | Lunamed AG | Use of Lipoteichoic Acid in the treatment of cancer in an inflammatory state |
| EP2574237A1 (en) | 2011-09-30 | 2013-04-03 | Lunamed AG | Use of a lipoteichoic acid, mono- or polyglycerophosphate for antibacterial pre-treatment and especially in medical devices |
| EP2589387A1 (en) | 2011-11-04 | 2013-05-08 | Lunamed AG | Use of a teichoic acid for the treatment of malignant liquor cerebrospinalis in the brain |
| EP2589388A1 (en) | 2011-11-04 | 2013-05-08 | Lunamed AG | Use of a Teichoic acid for the treatment of malignant ascites |
| KR20190137397A (ko) * | 2018-06-01 | 2019-12-11 | 경희대학교 산학협력단 | 리포테이코익산, TNF-α 및 IFN-γ를 유효성분으로 함유하는 항암용 조성물 |
| KR102259799B1 (ko) * | 2018-06-01 | 2021-06-02 | 경희대학교 산학협력단 | 리포테이코익산, TNF-α 및 IFN-γ를 유효성분으로 함유하는 항암용 조성물 |
| AU2020412749A1 (en) | 2019-12-27 | 2022-06-16 | Biopolis, S.L. | Uses of lipoteichoic acid from Bifidobacteria |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3729461A (en) * | 1970-12-23 | 1973-04-24 | Us Agriculture | Synthesis of glycosyl glycerides |
| SU787414A1 (ru) * | 1978-10-05 | 1980-12-15 | Московский Ордена Трудового Красного Знамени Институт Тонкой Химической Технологии Им. М.В. Ломоносова | Способ получени 1,2-ди-0-пальмитоил- 3-0-/6-0-(1,2-ди-0-пальмитоил- - глицеро-3-0-фосфорил)- - глюкопиранозил/- -глицерина |
| US4678773A (en) * | 1983-08-26 | 1987-07-07 | Chugai Seiyaku Kabushiki Kaisha | Antitumor agent |
| JPS61275217A (ja) * | 1985-05-29 | 1986-12-05 | Yakult Honsha Co Ltd | グラム陰性桿菌感染症防御剤 |
| JPS6456692A (en) * | 1987-08-27 | 1989-03-03 | Nisshin Oil Mills Ltd | Production of sugar glycerol |
| JPS6467237A (en) * | 1987-09-09 | 1989-03-13 | Nisshin Oil Mills Ltd | Novel surface active composition and emulsified composition combined therewith |
| NL9100510A (nl) * | 1991-03-21 | 1992-10-16 | Centraal Diergeneeskundig Inst | Dna-sequenties die coderen voor kenmerken van virulentie van streptococcus suis en delen daarvan, daarvan afgeleide polypeptiden en antilichamen, alsmede toepassing daarvan bij de diagnose van en de bescherming tegen infectie met s. suis bij zoogdieren, waaronder de mens. |
| AU6362594A (en) * | 1993-03-10 | 1994-09-26 | Miles Inc. | Hyaluronic acid used as a cancer treatment |
| CN1113102C (zh) * | 1995-01-30 | 2003-07-02 | 彼得·特鲁格 | 抗肿瘤制剂 |
-
1996
- 1996-01-24 CN CN96191668A patent/CN1113102C/zh not_active Expired - Fee Related
- 1996-01-24 AT AT96902922T patent/ATE219146T1/de active
- 1996-01-24 WO PCT/EP1996/000309 patent/WO1996023896A1/en not_active Ceased
- 1996-01-24 DE DE69621776T patent/DE69621776T2/de not_active Expired - Lifetime
- 1996-01-24 CA CA2208780A patent/CA2208780C/en not_active Expired - Fee Related
- 1996-01-24 JP JP52322796A patent/JP3638955B2/ja not_active Expired - Fee Related
- 1996-01-24 EP EP96902922A patent/EP0807185B9/en not_active Expired - Lifetime
- 1996-01-24 ES ES96902922T patent/ES2178699T3/es not_active Expired - Lifetime
- 1996-01-24 US US08/875,018 patent/US6114161A/en not_active Expired - Lifetime
- 1996-01-24 DK DK96902922T patent/DK0807185T3/da active
- 1996-01-24 AU AU47141/96A patent/AU4714196A/en not_active Abandoned
-
1999
- 1999-01-15 US US09/232,106 patent/US6214978B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0807185B1 (en) | 2002-06-12 |
| ES2178699T3 (es) | 2003-01-01 |
| CA2208780A1 (en) | 1996-08-08 |
| JPH11500901A (ja) | 1999-01-26 |
| CN1173206A (zh) | 1998-02-11 |
| US6214978B1 (en) | 2001-04-10 |
| CN1113102C (zh) | 2003-07-02 |
| EP0807185B9 (en) | 2002-12-11 |
| DE69621776T2 (de) | 2003-01-30 |
| AU4714196A (en) | 1996-08-21 |
| DE69621776D1 (de) | 2002-07-18 |
| CA2208780C (en) | 2010-03-30 |
| JP3638955B2 (ja) | 2005-04-13 |
| EP0807185A1 (en) | 1997-11-19 |
| ATE219146T1 (de) | 2002-06-15 |
| WO1996023896A1 (en) | 1996-08-08 |
| US6114161A (en) | 2000-09-05 |
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