ZA918292B - Galactomannan derivatives for coating or embedding medicinally active substances - Google Patents
Galactomannan derivatives for coating or embedding medicinally active substancesInfo
- Publication number
- ZA918292B ZA918292B ZA918292A ZA918292A ZA918292B ZA 918292 B ZA918292 B ZA 918292B ZA 918292 A ZA918292 A ZA 918292A ZA 918292 A ZA918292 A ZA 918292A ZA 918292 B ZA918292 B ZA 918292B
- Authority
- ZA
- South Africa
- Prior art keywords
- active substances
- embedding
- coating
- medicinally active
- mannose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0087—Glucomannans or galactomannans; Tara or tara gum, i.e. D-mannose and D-galactose units, e.g. from Cesalpinia spinosa; Tamarind gum, i.e. D-galactose, D-glucose and D-xylose units, e.g. from Tamarindus indica; Gum Arabic, i.e. L-arabinose, L-rhamnose, D-galactose and D-glucuronic acid units, e.g. from Acacia Senegal or Acacia Seyal; Derivatives thereof
- C08B37/0093—Locust bean gum, i.e. carob bean gum, with (beta-1,4)-D-mannose units in the main chain branched with D-galactose units in (alpha-1,6), e.g. from the seeds of carob tree or Ceratonia siliqua; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Emergency Medicine (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Displays For Variable Information Using Movable Means (AREA)
- Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Galactomannans whose hydroxyl groups are completely or partially in the form of low molecular weight aliphatic, araliphatic and/or aromatic ether or ester groups, and 20 to 80% of the mannose units present in the galactomannan chain form continuous mannose blocks of 2 to 20 mannose units which are not substituted by galactose groups, for encasings and/or embeddings of solid and/or liquid active substances, which release these active substances only in the colon or in the presence of glycolytic enzymes, process for the preparation thereof and pharmaceutical compositions prepared using such galactomannans are described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4033041 | 1990-10-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA918292B true ZA918292B (en) | 1992-07-29 |
Family
ID=6416524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA918292A ZA918292B (en) | 1990-10-18 | 1991-10-17 | Galactomannan derivatives for coating or embedding medicinally active substances |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0481240B1 (en) |
JP (1) | JP3020684B2 (en) |
KR (1) | KR920008060A (en) |
AT (1) | ATE146191T1 (en) |
AU (1) | AU636800B2 (en) |
BR (1) | BR9104502A (en) |
CA (1) | CA2053569A1 (en) |
CS (1) | CS315091A3 (en) |
DE (2) | DE4131292A1 (en) |
ES (1) | ES2095894T3 (en) |
FI (1) | FI914909A (en) |
HU (1) | HUT58263A (en) |
IE (1) | IE913649A1 (en) |
IL (1) | IL99760A0 (en) |
MC (1) | MC2280A1 (en) |
NO (1) | NO914077L (en) |
PT (1) | PT99254A (en) |
ZA (1) | ZA918292B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4119306C2 (en) * | 1991-06-12 | 1996-05-30 | Wheli Inter Ag | Organic raw materials, intermediate and end products for nutrition and for use for technical purposes that contain vital substances |
FR2688422A1 (en) * | 1992-03-11 | 1993-09-17 | Coletica | MICROCAPSULES WITH POLYSACCHARIDE WALLS CONTAINING PRIMARY ALCOHOL FUNCTIONS, AND COMPOSITIONS CONTAINING SAME. |
DE4236025A1 (en) | 1992-10-24 | 1994-04-28 | Merck Patent Gmbh | Oral dosage forms |
US5459257A (en) * | 1993-01-11 | 1995-10-17 | Dainippon Ink And Chemicals, Inc. | Sulfated oligoglycoside acylate and antiviral agent containing the same as active ingredient |
IT1265092B1 (en) * | 1993-05-31 | 1996-10-30 | Giuliani Spa | PREPARATION FOR USE AS A FOOD OR DIETARY SUPPLEMENT WITH TARGETED RELEASE IN THE COLON |
US5872246A (en) * | 1994-10-17 | 1999-02-16 | Aqualon Company | Ethyl guar |
US5656294A (en) * | 1995-06-07 | 1997-08-12 | Cibus Pharmaceutical, Inc. | Colonic delivery of drugs |
US5811388A (en) * | 1995-06-07 | 1998-09-22 | Cibus Pharmaceutical, Inc. | Delivery of drugs to the lower GI tract |
FR2746011B1 (en) * | 1996-03-12 | 1998-04-24 | STABLE JELLY COMPOSITION CONTAINING LIPOPHILIC INGREDIENTS SENSITIVE TO OXYGEN AND/OR WATER AND ITS USE IN THE COSMETIC AND/OR DERMATOLOGICAL FIELDS | |
FR2768357B1 (en) | 1997-09-18 | 1999-11-05 | Snecma | METHOD OF ASSEMBLING OR RECHARGING BY BRAZING-DIFFUSING PARTS IN TITANIUM ALUMINIURE |
DE102011082716A1 (en) * | 2011-09-14 | 2013-03-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Indicators element used in cell culture vessel for determining pH value of substance comprises polymeric material and indicator dye |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB498149A (en) * | 1937-07-29 | 1939-01-04 | Ig Farbenindustrie Ag | Improvements in the conversion of constituents of carob beans |
DE1617626C3 (en) * | 1966-08-30 | 1975-02-13 | Merck Patent Gmbh, 6100 Darmstadt | Use of galactomannans to stabilize solid, water-soluble vitamin B deep 12 preparations |
DE2130545A1 (en) * | 1971-06-19 | 1972-12-21 | Merck Patent Gmbh | Pharmaceutical molded body |
-
1991
- 1991-09-20 AT AT91116011T patent/ATE146191T1/en not_active IP Right Cessation
- 1991-09-20 DE DE4131292A patent/DE4131292A1/en not_active Withdrawn
- 1991-09-20 DE DE59108407T patent/DE59108407D1/en not_active Expired - Fee Related
- 1991-09-20 ES ES91116011T patent/ES2095894T3/en not_active Expired - Lifetime
- 1991-09-20 EP EP91116011A patent/EP0481240B1/en not_active Expired - Lifetime
- 1991-09-24 MC MC912214A patent/MC2280A1/en unknown
- 1991-10-14 HU HU913245A patent/HUT58263A/en unknown
- 1991-10-16 KR KR1019910018166A patent/KR920008060A/en not_active Application Discontinuation
- 1991-10-16 CA CA002053569A patent/CA2053569A1/en not_active Abandoned
- 1991-10-16 IL IL99760A patent/IL99760A0/en unknown
- 1991-10-17 JP JP3269186A patent/JP3020684B2/en not_active Expired - Fee Related
- 1991-10-17 NO NO91914077A patent/NO914077L/en unknown
- 1991-10-17 CS CS913150A patent/CS315091A3/en unknown
- 1991-10-17 ZA ZA918292A patent/ZA918292B/en unknown
- 1991-10-17 PT PT99254A patent/PT99254A/en not_active Application Discontinuation
- 1991-10-17 FI FI914909A patent/FI914909A/en not_active Application Discontinuation
- 1991-10-17 IE IE364991A patent/IE913649A1/en not_active Application Discontinuation
- 1991-10-17 AU AU85957/91A patent/AU636800B2/en not_active Ceased
- 1991-10-17 BR BR919104502A patent/BR9104502A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE4131292A1 (en) | 1992-04-23 |
HUT58263A (en) | 1992-02-28 |
AU636800B2 (en) | 1993-05-06 |
CA2053569A1 (en) | 1992-04-19 |
BR9104502A (en) | 1992-06-09 |
HU913245D0 (en) | 1992-01-28 |
KR920008060A (en) | 1992-05-27 |
ES2095894T3 (en) | 1997-03-01 |
MC2280A1 (en) | 1993-06-23 |
IL99760A0 (en) | 1992-08-18 |
FI914909A (en) | 1992-04-19 |
NO914077D0 (en) | 1991-10-17 |
ATE146191T1 (en) | 1996-12-15 |
DE59108407D1 (en) | 1997-01-23 |
JP3020684B2 (en) | 2000-03-15 |
NO914077L (en) | 1992-04-21 |
JPH04264102A (en) | 1992-09-18 |
CS315091A3 (en) | 1992-05-13 |
IE913649A1 (en) | 1992-04-22 |
FI914909A0 (en) | 1991-10-17 |
AU8595791A (en) | 1992-05-21 |
EP0481240A2 (en) | 1992-04-22 |
EP0481240A3 (en) | 1993-04-21 |
PT99254A (en) | 1992-08-31 |
EP0481240B1 (en) | 1996-12-11 |
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