DK0807173T3 - Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf - Google Patents
Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse derafInfo
- Publication number
- DK0807173T3 DK0807173T3 DK95944237T DK95944237T DK0807173T3 DK 0807173 T3 DK0807173 T3 DK 0807173T3 DK 95944237 T DK95944237 T DK 95944237T DK 95944237 T DK95944237 T DK 95944237T DK 0807173 T3 DK0807173 T3 DK 0807173T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunoglobulins
- plants
- preparation
- methods
- pathogens
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36739594A | 1994-12-30 | 1994-12-30 | |
US08/434,000 US6046037A (en) | 1994-12-30 | 1995-05-04 | Method for producing immunoglobulins containing protection proteins in plants and their use |
PCT/US1995/016889 WO1996021012A1 (en) | 1994-12-30 | 1995-12-27 | Methods for producing immunoglobulins containing protection proteins in plants and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0807173T3 true DK0807173T3 (da) | 2008-01-07 |
Family
ID=27003775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95944237T DK0807173T3 (da) | 1994-12-30 | 1995-12-27 | Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf |
Country Status (11)
Country | Link |
---|---|
US (2) | US6303341B1 (ja) |
EP (2) | EP0807173B1 (ja) |
JP (1) | JPH11504901A (ja) |
CN (1) | CN1183802A (ja) |
AT (1) | ATE369423T1 (ja) |
AU (1) | AU722668B2 (ja) |
CA (1) | CA2208783C (ja) |
DE (1) | DE69535557T2 (ja) |
DK (1) | DK0807173T3 (ja) |
ES (1) | ES2292173T3 (ja) |
WO (1) | WO1996021012A1 (ja) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7005560B1 (en) * | 1989-10-27 | 2006-02-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US5959177A (en) * | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US6808709B1 (en) | 1994-12-30 | 2004-10-26 | The Regents Of The University Of California | Immunoglobulins containing protection proteins and their use |
US5990385A (en) * | 1997-11-10 | 1999-11-23 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Protein production in transgenic alfalfa plants |
WO1999049024A2 (en) * | 1998-03-25 | 1999-09-30 | Planet Biotechnology, Inc. | Methods and compositions for production of multimeric proteins in transgenic plants |
US7485715B2 (en) * | 1999-06-18 | 2009-02-03 | Ceres, Inc. | Sequence-determined DNA encoding AP2 domain polypeptides |
US7479555B2 (en) * | 1999-07-21 | 2009-01-20 | Ceres, Inc. | Polynucleotides having a nucleotide sequence that encodes a polypeptide having MOV34 family activity |
IL151972A0 (en) * | 2000-03-27 | 2003-04-10 | Univ California | Ligands directed to the non-secretory component, non-stalk region of pigr and methods of use thereof |
US20060015969A1 (en) * | 2000-04-28 | 2006-01-19 | Planet Biotechnology, Inc. | Novel immunoadhesins for treating and prventing toxicity and pathogen-mediated diseases |
EP1290027B1 (en) | 2000-04-28 | 2009-09-09 | Planet Biotechnology, Inc. | Immunoadhesin for the prevention of rhinovirus infection |
US7304208B2 (en) * | 2000-05-02 | 2007-12-04 | Ventria Bioscience | Expression of human serum albumin (HSA) in monocot seeds |
US6696620B2 (en) * | 2000-05-02 | 2004-02-24 | Epicyte Pharmaceutical, Inc. | Immunoglobulin binding protein arrays in eukaryotic cells |
JP2004506695A (ja) * | 2000-08-24 | 2004-03-04 | ワシントン デンタル サービス | う蝕の予防の免疫学的方法 |
WO2002102979A2 (en) * | 2001-06-15 | 2002-12-27 | UNIVERSITY OF TOLEDO, THE a University instrumentality of the State of Ohio | Transformation of mono- and di- cotyledonous plants |
US20070118934A1 (en) * | 2001-10-26 | 2007-05-24 | Planet Biotechnology, Inc. | Chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax |
USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
ATE514717T1 (de) * | 2002-07-18 | 2011-07-15 | Merus B V | Rekombinante produktion von antikörpermischungen |
US7476777B2 (en) * | 2002-09-17 | 2009-01-13 | Ceres, Inc. | Biological containment system |
WO2004027038A2 (en) * | 2002-09-17 | 2004-04-01 | Ceres, Inc. | Biological containment system |
WO2004106375A1 (en) | 2003-05-30 | 2004-12-09 | Merus Biopharmaceuticals B.V. I.O. | Fab library for the preparation of anti vegf and anti rabies virus fabs |
US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
US20050138692A1 (en) * | 2003-06-02 | 2005-06-23 | Biotechnology Foundation, Inc. | Production of cancer-specific antibodies in plants |
JP2007517504A (ja) * | 2003-12-09 | 2007-07-05 | ベントリア バイオサイエンス | 融合担体として種子貯蔵蛋白を利用する植物種子中の融合ポリペプチドの高水準発現 |
CA2551392A1 (en) * | 2003-12-23 | 2005-07-28 | Ventria Bioscience | Methods of expressing heterologous protein in plant seeds using monocot non seed-storage protein promoters |
CA2554054C (en) | 2004-01-20 | 2013-06-04 | Merus B.V. | Mixtures of binding proteins |
US9758790B2 (en) | 2004-12-08 | 2017-09-12 | Ceres, Inc. | Modulating the level of components within plants |
WO2007050625A1 (en) * | 2005-10-25 | 2007-05-03 | Ceres, Inc. | Modulation of triterpenoid content in plants |
AU2006216715A1 (en) * | 2005-02-22 | 2006-08-31 | Ceres Inc. | Modulating plant alkaloids |
US7312376B2 (en) * | 2005-04-20 | 2007-12-25 | Ceres, Inc. | Regulatory regions from Papaveraceae |
US8124839B2 (en) * | 2005-06-08 | 2012-02-28 | Ceres, Inc. | Identification of terpenoid-biosynthesis related regulatory protein-regulatory region associations |
ES2426194T3 (es) * | 2005-08-02 | 2013-10-21 | Planet Biotechnology, Inc. | Proteínas quiméricas del receptor de toxina mejoradas y proteínas quiméricas del receptor de toxina para el tratamiento y la prevención de anthrax |
US20100062137A1 (en) * | 2005-09-30 | 2010-03-11 | Steven Craig Bobzin | Modulating plant tocopherol levels |
US20070199090A1 (en) * | 2006-02-22 | 2007-08-23 | Nestor Apuya | Modulating alkaloid biosynthesis |
WO2007117693A2 (en) * | 2006-04-07 | 2007-10-18 | Ceres, Inc. | Regulatory protein-regulatory region associations related to alkaloid biosynthesis |
US8470308B2 (en) * | 2009-01-03 | 2013-06-25 | Ray C. Wasielewski | Enhanced medical implant comprising disrupted tooth pulp and tooth particles |
US10328103B2 (en) | 2009-01-03 | 2019-06-25 | Ray C. Wasielewski | Medical treatment composition comprising mammalian dental pulp stem cells |
PT2838917T (pt) | 2012-04-20 | 2019-09-12 | Merus Nv | Métodos e meios para a produção de moléculas similares a ig heterodiméricas |
PL2888283T3 (pl) | 2012-08-24 | 2019-03-29 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
EP2762496A1 (en) | 2013-02-05 | 2014-08-06 | EngMab AG | Method for the selection of antibodies against BCMA |
WO2014122143A1 (en) | 2013-02-05 | 2014-08-14 | Engmab Ag | Method for the selection of antibodies against bcma |
WO2014124457A1 (en) * | 2013-02-11 | 2014-08-14 | University Of Louisville Research Foundation, Inc. | Methods for producing antibodies |
EP2789630A1 (en) | 2013-04-09 | 2014-10-15 | EngMab AG | Bispecific antibodies against CD3e and ROR1 |
CA2963692A1 (en) | 2014-10-09 | 2016-04-14 | Engmab Ag | Bispecific antibodies against cd3epsilon and ror1 |
EA202092435A3 (ru) | 2015-08-03 | 2021-06-30 | Энгмаб Сарл | Моноклональные антитела против bcma |
US10688181B2 (en) | 2016-06-27 | 2020-06-23 | The Regents Of The University Of California | Cancer treatment combinations |
WO2018083204A1 (en) | 2016-11-02 | 2018-05-11 | Engmab Sàrl | Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma |
JP2021536489A (ja) * | 2018-09-05 | 2021-12-27 | ベントリア、バイオサイエンス、インコーポレイテッドVentria Bioscience Inc. | 免疫グロブリンa製剤 |
US12016885B2 (en) | 2018-11-06 | 2024-06-25 | Alsatech, Inc. | Method of solubilizing TDP-43 protein aggregates in amyotrophic lateral sclerosis using a microvascular endothelial cell expressing an anti-TDP-43 Fab |
CN113875778A (zh) * | 2021-09-29 | 2022-01-04 | 季红进 | 含有植物免疫活性蛋白和5-氨基乙酰丙酸或其衍生物的生物刺激剂 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
US4443549A (en) | 1981-10-19 | 1984-04-17 | Molecular Genetics, Inc. | Production of monoclonal antibodies against bacterial adhesins |
US4652448A (en) | 1982-10-07 | 1987-03-24 | Molecular Genetics, Inc. | Use of monoclonal antibodies against bacterial adhesins |
US4870009A (en) | 1982-11-22 | 1989-09-26 | The Salk Institute For Biological Studies | Method of obtaining gene product through the generation of transgenic animals |
US5034322A (en) | 1983-01-17 | 1991-07-23 | Monsanto Company | Chimeric genes suitable for expression in plant cells |
US5352605A (en) | 1983-01-17 | 1994-10-04 | Monsanto Company | Chimeric genes for transforming plant cells using viral promoters |
GB8303994D0 (en) | 1983-02-14 | 1983-03-16 | Council Of Governors Of United | Antigenic materials |
FI68590C (fi) | 1984-03-15 | 1985-10-10 | Rosenlew Ab Oy W | Flexibel behaollare foer transport och lagring av massagods |
US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
WO1987000551A1 (en) | 1985-07-16 | 1987-01-29 | The Salk Institute For Biological Studies | Genetic alteration of plants with retroviruses |
CA1313830C (en) | 1985-08-07 | 1993-02-23 | Dilip Maganlal Shah | Glyphosate-resistant plants |
US5352446A (en) | 1986-03-25 | 1994-10-04 | Council Of Governors Of The United Medical And Dental Schools Of Guy's And St. Thomas's Hospitals | Method of treating dental caries with monoclonal antibodies against the antigen I and antigen I/II of streptococcus mutans |
GB8704648D0 (en) | 1987-02-27 | 1987-04-01 | Guy S & St Thomas S Hospitals | Antibodies |
US5352440A (en) | 1988-03-30 | 1994-10-04 | Trustees Of Boston University | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof |
DE68923728T2 (de) | 1988-04-25 | 1996-02-22 | Monsanto Co | Insektenresistente Salatpflanzen. |
US5183756A (en) | 1988-08-19 | 1993-02-02 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibody (D612) having selective reactivity for gastrointestinal caricinomas and method for employing the same |
CA2016842A1 (en) | 1989-05-16 | 1990-11-16 | Richard A. Lerner | Method for tapping the immunological repertoire |
US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US5202422A (en) | 1989-10-27 | 1993-04-13 | The Scripps Research Institute | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use |
CN1057785A (zh) * | 1990-04-16 | 1992-01-15 | 哈佛大学校长及研究员协会 | 合成多聚免疫球蛋白受体,受体-抗体复合物,生产及应用 |
JPH04169539A (ja) | 1990-11-01 | 1992-06-17 | Imuno Japan:Kk | 消化器疾患治療・予防剤およびその製造方法 |
-
1995
- 1995-12-27 DE DE69535557T patent/DE69535557T2/de not_active Expired - Lifetime
- 1995-12-27 AT AT95944237T patent/ATE369423T1/de active
- 1995-12-27 WO PCT/US1995/016889 patent/WO1996021012A1/en active IP Right Grant
- 1995-12-27 DK DK95944237T patent/DK0807173T3/da active
- 1995-12-27 ES ES95944237T patent/ES2292173T3/es not_active Expired - Lifetime
- 1995-12-27 CA CA2208783A patent/CA2208783C/en not_active Expired - Fee Related
- 1995-12-27 EP EP95944237A patent/EP0807173B1/en not_active Expired - Lifetime
- 1995-12-27 EP EP07113307A patent/EP1911767A3/en not_active Withdrawn
- 1995-12-27 JP JP8521124A patent/JPH11504901A/ja not_active Withdrawn
- 1995-12-27 CN CN95197699A patent/CN1183802A/zh active Pending
- 1995-12-27 AU AU46088/96A patent/AU722668B2/en not_active Ceased
-
1999
- 1999-05-14 US US09/312,157 patent/US6303341B1/en not_active Expired - Fee Related
-
2001
- 2001-10-16 US US09/982,107 patent/US20020159958A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU4608896A (en) | 1996-07-24 |
US20020159958A1 (en) | 2002-10-31 |
AU722668B2 (en) | 2000-08-10 |
ATE369423T1 (de) | 2007-08-15 |
DE69535557T2 (de) | 2008-04-30 |
CA2208783C (en) | 2010-09-28 |
CN1183802A (zh) | 1998-06-03 |
JPH11504901A (ja) | 1999-05-11 |
EP1911767A2 (en) | 2008-04-16 |
CA2208783A1 (en) | 1996-07-11 |
US6303341B1 (en) | 2001-10-16 |
DE69535557D1 (de) | 2007-09-20 |
EP0807173B1 (en) | 2007-08-08 |
ES2292173T3 (es) | 2008-03-01 |
EP1911767A3 (en) | 2008-09-10 |
WO1996021012A1 (en) | 1996-07-11 |
EP0807173A1 (en) | 1997-11-19 |
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