DK0796280T3 - Murint monoklonalt anti-idiotypisk antistof 3H1 - Google Patents

Murint monoklonalt anti-idiotypisk antistof 3H1

Info

Publication number
DK0796280T3
DK0796280T3 DK95944582T DK95944582T DK0796280T3 DK 0796280 T3 DK0796280 T3 DK 0796280T3 DK 95944582 T DK95944582 T DK 95944582T DK 95944582 T DK95944582 T DK 95944582T DK 0796280 T3 DK0796280 T3 DK 0796280T3
Authority
DK
Denmark
Prior art keywords
monoclonal anti
cea
murine monoclonal
idiotypic antibody
provides
Prior art date
Application number
DK95944582T
Other languages
Danish (da)
English (en)
Inventor
Malaya Chatterjee
Heinz Kohler
Sunil K Chatterjee
Kenneth A Foon
Original Assignee
Univ Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kentucky filed Critical Univ Kentucky
Application granted granted Critical
Publication of DK0796280T3 publication Critical patent/DK0796280T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK95944582T 1994-12-28 1995-12-28 Murint monoklonalt anti-idiotypisk antistof 3H1 DK0796280T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36548494A 1994-12-28 1994-12-28
PCT/US1995/017105 WO1996020219A2 (en) 1994-12-28 1995-12-28 Murine monoclonal anti-idiotype antibody 3h1

Publications (1)

Publication Number Publication Date
DK0796280T3 true DK0796280T3 (da) 2003-04-22

Family

ID=23439088

Family Applications (2)

Application Number Title Priority Date Filing Date
DK95944450T DK0800578T3 (da) 1994-12-28 1995-12-28 Rekombinant monoklonalt anti-idiotype antistof 3H1
DK95944582T DK0796280T3 (da) 1994-12-28 1995-12-28 Murint monoklonalt anti-idiotypisk antistof 3H1

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK95944450T DK0800578T3 (da) 1994-12-28 1995-12-28 Rekombinant monoklonalt anti-idiotype antistof 3H1

Country Status (12)

Country Link
US (3) US7090842B1 (de)
EP (3) EP0796280B1 (de)
JP (2) JPH11500607A (de)
AT (2) ATE237687T1 (de)
AU (2) AU717779C (de)
CA (2) CA2209172C (de)
DE (2) DE69530107T2 (de)
DK (2) DK0800578T3 (de)
ES (2) ES2197217T3 (de)
MX (2) MX9704898A (de)
PT (2) PT796280E (de)
WO (2) WO1996020219A2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2209172C (en) * 1994-12-28 2007-04-10 University Of Kentucky Murine monoclonal anti-idiotype antibody 3h1
US6235280B1 (en) * 1996-04-12 2001-05-22 Malaya Chatterjee Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1
US20020041872A1 (en) 1996-04-12 2002-04-11 Malaya Chatterjee Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1
US7318921B2 (en) * 1996-05-15 2008-01-15 Altarex Medical Corp. Therapeutic compositions that alter the immune response
US6241985B1 (en) * 1996-05-15 2001-06-05 Altarex Corp. Method and composition for reconforming multi-epitopic antigens to initiate an immune response
US20080220012A1 (en) * 1996-05-15 2008-09-11 Ragupathy Madiyalakan Therapeutic Compositions that alter the immune response
US20020098190A1 (en) * 1997-06-13 2002-07-25 Malaya Chatterjee Compositions and methods for treating tumors bearing HMFG and CEA antigens
NZ501990A (en) * 1997-07-08 2002-09-27 Viventia Biotech Inc Compositions containing antigen-binding fragments that recognise the antigen recognised by a recombinant 4B5 antibody
US7569674B2 (en) 1998-05-04 2009-08-04 Innexus Biotechnology International Limited Autophilic antibodies
US6355244B1 (en) 1997-11-17 2002-03-12 University Of Kentucky Research Foundation Methods and compositions for the treatment of psoriasis
AT409086B (de) * 1999-11-16 2002-05-27 Igeneon Krebs Immuntherapie Neue verwendung von antikörpern als impfstoffe
US6774209B1 (en) 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
US8101200B2 (en) 2000-04-13 2012-01-24 Angiotech Biocoatings, Inc. Targeted therapeutic agent release devices and methods of making and using the same
DE20105649U1 (de) * 2001-03-30 2001-08-16 Wang Ming Theng Kettenzahnrad und Ratschenanordnung geringer Reibung für die rückwärtige Nabe eines Zweirades
US8029803B2 (en) * 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
AT500650B1 (de) * 2003-04-17 2009-11-15 Altropus Gmbh Immunogener rekombinanter antikörper
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
CN101005941B (zh) * 2004-08-05 2010-06-16 R&D绿色材料公司 用于制造固体可生物降解制品的低温模塑方法
AU2005309434A1 (en) * 2004-11-24 2006-06-01 Board Of Regents, The University Of Texas System Method for identifying and designing immunogenic peptides
CN101300355A (zh) * 2005-10-13 2008-11-05 威瑞克斯医药公司 包含丙型肝炎病毒多肽和用于引起免疫应答的Fc片段的嵌合抗原
JP5165672B2 (ja) * 2006-03-29 2013-03-21 キングス カレッジ ロンドン Ｔｓｈｒに対するアゴニスト抗体
TWI434855B (zh) * 2006-11-21 2014-04-21 Hoffmann La Roche 結合物及其在免疫分析中作為參考標準之用途
CA2700197C (en) 2007-11-08 2020-09-08 Neogenix Oncology, Inc. Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
US8093018B2 (en) * 2008-05-20 2012-01-10 Otsuka Pharmaceutical Co., Ltd. Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
KR101761541B1 (ko) * 2009-10-26 2017-07-26 네스텍 소시에테아노님 항-ｔｎｆ 약물 및 자가항체의 검출을 위한 검정법
AU2011317149B2 (en) 2010-10-18 2015-05-07 Société des Produits Nestlé S.A. Methods for determining anti-drug antibody isotypes
JP6181646B2 (ja) 2011-07-06 2017-08-16 ネステク ソシエテ アノニム Ｔｎｆアルファによる生物学的治療に対する中和自己抗体の検出のためのアッセイ
MA40094B1 (fr) * 2014-08-06 2022-05-31 Univ Miami Protéines de fusion de l'interleukine-2/récepteur alpha de l'interleukine-2 et procédés d'utilisation
WO2016088104A2 (en) 2014-12-05 2016-06-09 Nestec S.A. Indirect homogeneous mobility shift assays for the detection of biologics in patient samples
CA3094112A1 (en) 2018-03-28 2019-10-03 Bristol-Myers Squibb Company Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
JPS54140710A (en) * 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
JPS56145222A (en) * 1980-04-28 1981-11-11 Toshiyuki Hamaoka Improved antibody and its preparation
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4436728A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
EP0141783B2 (de) 1983-11-07 1993-06-16 The Wistar Institute Durch antiidiotype Antikörper induzierte immune Antwort zu Tumoren und Viren
US5053224A (en) 1983-11-07 1991-10-01 Hilary Koprowski Induction of antibody response to solid tumors with anti-idiotype antibodies
US4828991A (en) * 1984-01-31 1989-05-09 Akzo N.V. Tumor specific monoclonal antibodies
US5180814A (en) 1984-01-31 1993-01-19 Akzo N.V. Tumor specific monoclonal antibodies
US5106738A (en) 1984-01-31 1992-04-21 Akzo Nv Tumor specific monoclonal antibodies
US5171568A (en) * 1984-04-06 1992-12-15 Chiron Corporation Recombinant herpes simplex gb-gd vaccine
US4722840A (en) 1984-09-12 1988-02-02 Chiron Corporation Hybrid particle immunogens
US5160723A (en) 1985-04-19 1992-11-03 Sloan-Kettering Institute For Cancer Research Method of imaging colorectal carcinoma lesion and composition for use therein
GB2202017A (en) * 1987-03-07 1988-09-14 Alvan Michael Judson Anti-lock electric braking
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
JP2517343B2 (ja) * 1988-01-26 1996-07-24 富士写真フイルム株式会社 熱現像感光材料
JPH01207920A (ja) 1988-02-16 1989-08-21 Oki Electric Ind Co Ltd ＩｎＰ半導体薄膜の製造方法
GB8812137D0 (en) 1988-05-23 1988-06-29 Imp Cancer Res Tech Antibodies
US5183756A (en) * 1988-08-19 1993-02-02 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibody (D612) having selective reactivity for gastrointestinal caricinomas and method for employing the same
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5407684A (en) * 1988-12-30 1995-04-18 Virginia Commonwealth University Use of DHEA as a medicinal
US5077284A (en) 1988-12-30 1991-12-31 Loria Roger M Use of dehydroepiandrosterone to improve immune response
GB8928874D0 (en) * 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5244801A (en) 1989-12-28 1993-09-14 Martin Tobi Process for producing monoclonal antibodies which specifically bind to benign colonic adenomatous polyps of human origin and hybridomas and monoclonal antibodies produced by said process
EP0438803B1 (de) * 1990-01-26 1997-03-12 Immunomedics, Inc. Impfstoffe gegen Krebs und Infektionskrankheiten
US5200316A (en) 1990-02-15 1993-04-06 Miles Inc. Immunoassay methods using noncross reactive cea gene family members antibodies
ATE147990T1 (de) 1990-05-10 1997-02-15 Dana Farber Cancer Inst Inc Erhöhung der assoziation exogener peptide mit mhci-molekülen auf zellen des immunsystems
US5608039A (en) * 1990-10-12 1997-03-04 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Single chain B3 antibody fusion proteins and their uses
GB9105992D0 (en) 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccine
WO1993006233A1 (en) 1991-09-19 1993-04-01 Manson Lionel A Tumor immunotherapy utilizing a method of overcoming the resistance of a progressively growing tumor
US5227471A (en) * 1992-01-30 1993-07-13 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Monoclonal antibody PD41 that binds to a prostate mucin antigen that is expressed in human prostatic carcinoma
JPH08502954A (ja) 1992-08-31 1996-04-02 ジェナー テクノロジーズ 抗−イディオタイプ抗体を用いた抗腫瘍ｔ細胞応答の刺激
CA2209172C (en) * 1994-12-28 2007-04-10 University Of Kentucky Murine monoclonal anti-idiotype antibody 3h1

Also Published As

Publication number Publication date
PT796280E (pt) 2003-08-29
JPH11500607A (ja) 1999-01-19
ATE237687T1 (de) 2003-05-15
PT800578E (pt) 2003-09-30
DE69530107T2 (de) 2003-10-16
AU4692796A (en) 1996-07-19
ES2196098T3 (es) 2003-12-16
ES2197217T3 (es) 2004-01-01
AU4649896A (en) 1996-07-19
AU717779C (en) 2002-12-05
WO1996020277A2 (en) 1996-07-04
EP1298144A2 (de) 2003-04-02
WO1996020219A3 (en) 1996-09-06
US5977315A (en) 1999-11-02
EP0800578A2 (de) 1997-10-15
EP0800578B1 (de) 2003-04-16
EP0796280A2 (de) 1997-09-24
CA2209360C (en) 2010-07-06
JPH10511846A (ja) 1998-11-17
DK0800578T3 (da) 2003-08-11
WO1996020219A2 (en) 1996-07-04
US7090842B1 (en) 2006-08-15
DE69530415D1 (de) 2003-05-22
MX9704897A (es) 1998-06-28
EP0796280B1 (de) 2003-03-26
EP1298144A3 (de) 2006-05-31
AU704829B2 (en) 1999-05-06
DE69530107D1 (de) 2003-04-30
ATE235514T1 (de) 2003-04-15
MX9704898A (es) 1998-06-28
CA2209172C (en) 2007-04-10
WO1996020277A3 (en) 1996-09-06
CA2209360A1 (en) 1996-07-04
DE69530415T2 (de) 2004-02-12
AU717779B2 (en) 2000-03-30
CA2209172A1 (en) 1996-07-04
US20010047083A1 (en) 2001-11-29

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