DK0784483T3 - Præparat indeholdende et rekombinant virus, der udtrykker et antigen, og et rekombinant virus, der udtrykker et immunstimul - Google Patents
Præparat indeholdende et rekombinant virus, der udtrykker et antigen, og et rekombinant virus, der udtrykker et immunstimulInfo
- Publication number
- DK0784483T3 DK0784483T3 DK95935264T DK95935264T DK0784483T3 DK 0784483 T3 DK0784483 T3 DK 0784483T3 DK 95935264 T DK95935264 T DK 95935264T DK 95935264 T DK95935264 T DK 95935264T DK 0784483 T3 DK0784483 T3 DK 0784483T3
- Authority
- DK
- Denmark
- Prior art keywords
- recombinant virus
- virus expressing
- antigen
- composition containing
- immune stimulus
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/46448—Cancer antigens from embryonic or fetal origin
- A61K39/464482—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70532—B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31726894A | 1994-10-03 | 1994-10-03 | |
US08/483,316 US6045802A (en) | 1994-10-03 | 1995-06-07 | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
PCT/US1995/012624 WO1996010419A2 (fr) | 1994-10-03 | 1995-10-02 | Composition comprenant un virus de recombinaison exprimant un antigene et un virus de recombinaison exprimant une molecule immunostimulatrice |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0784483T3 true DK0784483T3 (da) | 2001-03-26 |
Family
ID=26980864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95935264T DK0784483T3 (da) | 1994-10-03 | 1995-10-02 | Præparat indeholdende et rekombinant virus, der udtrykker et antigen, og et rekombinant virus, der udtrykker et immunstimul |
Country Status (12)
Country | Link |
---|---|
US (3) | US6548068B1 (fr) |
EP (2) | EP0784483B1 (fr) |
JP (3) | JP3907698B2 (fr) |
AT (1) | ATE197765T1 (fr) |
AU (1) | AU688606B2 (fr) |
CA (1) | CA2201587C (fr) |
DE (1) | DE69519521T2 (fr) |
DK (1) | DK0784483T3 (fr) |
ES (1) | ES2154738T3 (fr) |
GR (1) | GR3035458T3 (fr) |
PT (1) | PT784483E (fr) |
WO (1) | WO1996010419A2 (fr) |
Families Citing this family (113)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994024267A1 (fr) * | 1993-04-20 | 1994-10-27 | Robinson, William, S. | Methode et materiel de traitement de patients infectes par des agents infectieux intracellulaires |
AU718945B2 (en) * | 1996-07-25 | 2000-05-04 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
CA2261989C (fr) * | 1996-07-25 | 2008-09-30 | Therion Biologics Corporation | Poxvirus recombinant pour l'immunisation contre des antigenes associes aux tumeurs |
EP1012276A2 (fr) | 1997-02-24 | 2000-06-28 | Therion Biologics Corporation | Poxvirus recombine destine a une immunisation contre l'antigene associe aux tumeurs muc1 |
US6730512B2 (en) * | 1997-04-09 | 2004-05-04 | Amdl, Inc. | Combination immunogene therapy |
TW586934B (en) * | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
EP1015035B1 (fr) * | 1997-08-13 | 2009-01-28 | The Uab Research Foundation | Vaccination par application topique de vecteurs genetiques |
WO2000034494A1 (fr) * | 1998-12-09 | 2000-06-15 | The Government Of The United States Of America Represented By The Secretary, Department Of Health And Human Services | Vecteur recombine exprimant des molecules costimulantes multiples et leurs utilisations |
US6969609B1 (en) | 1998-12-09 | 2005-11-29 | The United States Of America As Represented By The Department Of Health And Human Serivces | Recombinant vector expressing multiple costimulatory molecules and uses thereof |
DE69935781T2 (de) | 1998-02-20 | 2007-12-27 | University Of Miami, Miami | Modifizierter hitzeschockprotein/peptidantigen komplex |
KR20070039615A (ko) * | 1998-02-27 | 2007-04-12 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 백신, 면역치료제 및 그의 이용 방법 |
US7279168B2 (en) | 1998-05-01 | 2007-10-09 | Texas A & M University System | Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof |
KR100869861B1 (ko) * | 1998-05-01 | 2008-11-24 | 쉐링-프라우 리미티드 | 고양이 cd80, 고양이 cd86, 고양이 cd28, 및 고양이ctla4 핵산과 폴리펩티드 |
WO1999057295A1 (fr) * | 1998-05-01 | 1999-11-11 | Schering-Plough Ltd. | Virus de recombinaison exprimant un adn etranger codant les cd80, cd86, ctla-4 ou cd86 felins et applications |
EP1865065A1 (fr) * | 1998-12-09 | 2007-12-12 | The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services | Vecteur recombinant exprimant plusieurs molécules costimulantes et ses utilisations |
WO2001016320A1 (fr) * | 1999-08-30 | 2001-03-08 | Ludwig Institute For Cancer Research | Nonapeptides et decapeptides se fixant aux molecules hla et utilisation |
WO2001024832A2 (fr) * | 1999-09-27 | 2001-04-12 | Gabriele Pecher | Composition pharmaceutique pour assurer le traitement et la prophylaxie de tumeurs chez l'homme, qui expriment l'antigene tumoral mucine et/ou l'antigene carcino-embryonnaire et son utilisation |
EP1218393A4 (fr) * | 1999-10-06 | 2004-03-31 | Univ Pennsylvania | Compositions de ciblage de cellules et procedes d'utilisation de celles-ci |
AU1013701A (en) | 1999-10-22 | 2001-05-08 | Aventis Pasteur Limited | Modified gp100 and uses thereof |
ES2276788T3 (es) * | 2000-05-10 | 2007-07-01 | Sanofi Pasteur Limited | Polipeptidos inmunogenos codificados por minigenes mage y sus utilizaciones. |
GB0111442D0 (en) * | 2001-05-10 | 2001-07-04 | Isis Innovation | Method for preparing recombinant virus |
US20030148973A1 (en) * | 2001-05-23 | 2003-08-07 | Peter Emtage | MAGE-A1 peptides for treating or preventing cancer |
US20040091995A1 (en) * | 2001-06-15 | 2004-05-13 | Jeffrey Schlom | Recombinant non-replicating virus expressing gm-csf and uses thereof to enhance immune responses |
EP1281767A3 (fr) | 2001-07-31 | 2003-05-28 | Aladar A. Szalay | Microbes et cellules lumineuses pour le diagnostic et le traitement des tumeurs |
US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
WO2003085087A2 (fr) | 2002-04-09 | 2003-10-16 | Aventis Pasteur, Limited | Acide nucleique d'antigene carcinoembryonnaire modifie et vecteurs d'expression |
US20030228261A1 (en) * | 2002-06-05 | 2003-12-11 | Aladar Szalay | Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue |
EP1369491A1 (fr) * | 2002-06-05 | 2003-12-10 | Aladar A. Szalay | Microorganismes et cellules luminescents pour le diagnostic et la thérapie de maladies asociées avec du tissu blessé ou inflammé |
US20040101522A1 (en) * | 2002-09-12 | 2004-05-27 | Therion Biologics Corporation | Transduced neoplastic cell preparations able to express T-cell costimulatory molecules B7.1, ICAM-1, and LFA-3 and induce immunostimulatory prophylactic and therapeutic anti-tumor effects in-vivo |
CA2510238A1 (fr) * | 2002-10-22 | 2004-05-06 | Sanofi Pasteur Limited | Traitement anticancereux utilisant un vaccin et des doses elevees de cytokine |
US8207314B2 (en) * | 2003-05-16 | 2012-06-26 | Sanofi Pasteur Limited | Tumor antigens for prevention and/or treatment of cancer |
SG179291A1 (en) | 2003-06-18 | 2012-04-27 | Genelux Corp | Modified recombinant vaccinia viruses and other microorganisms, uses thereof |
WO2005005465A2 (fr) * | 2003-07-08 | 2005-01-20 | Board Of Regents, University Of Texas System | Procedes et compositions permettant d'ameliorer des reactions immunitaires par l'intermediaire d'antigenes de rappel |
JP4668919B2 (ja) * | 2003-10-08 | 2011-04-13 | サノフィ パストゥール インコーポレイテッド | 修飾cea/b7ベクター |
EP1697399B1 (fr) | 2003-12-12 | 2016-11-23 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS | Epitope de lymphocyte t cytotoxique humain et son epitope agoniste issus du nombre non variable de sequences repetees en tandem de muc-1 |
JP2008501360A (ja) * | 2004-06-11 | 2008-01-24 | カソリック ユニバーシティー インダストリー アカデミー コオペレーション ファウンデーション | CEA−特異的な細胞毒性T細胞を生成する組み換えアデノウイルスAdVCEAで形質導入された樹枝状細胞、及びこれを含むワクチン並びに薬剤学的組成物 |
WO2007097370A1 (fr) | 2006-02-22 | 2007-08-30 | Riken | IMMUNOTHERAPIE PAR L'UTILISATION D'UNE CELLULE CAPABLE DE CO-EXPRIMER UN ANTIGENE CIBLE ET LE CD1d ET PULSEE PAR UN LIGAND DU CD1d |
ATE485305T1 (de) | 2006-02-24 | 2010-11-15 | Us Gov Health & Human Serv | Immunogene peptide und verwendungsverfahren dafür |
BRPI0708912B8 (pt) | 2006-03-14 | 2021-07-27 | Univ Oregon Health & Science | métodos in vitro para detecção de mycobacterium tuberculosis e de células t expressando cd8 que especificamente reconhecem seq id no: 11 em um indivíduo |
TW200819540A (en) | 2006-07-11 | 2008-05-01 | Genelux Corp | Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders |
EP2097517B1 (fr) | 2006-10-16 | 2014-06-04 | Genelux Corporation | Virus recombinant de la vaccine de souche Lister codant pour un anticorps anti-VEGF à chaîne unique |
AU2008221383B2 (en) * | 2007-02-28 | 2012-09-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
WO2008156655A2 (fr) * | 2007-06-15 | 2008-12-24 | Genelux Corporation | Microorganismes pour une imagerie et/ou un traitement de tumeurs |
EP2202297B1 (fr) * | 2007-07-18 | 2014-05-14 | Genelux Corporation | Utilisation d'un agent chemothérapeutique dans la préparation d'un médicament pour le traitement ou l'amélioration d'effets collatéraux des thérapies avec virus oncolytique |
CN102014937A (zh) | 2008-03-03 | 2011-04-13 | 迈阿密大学 | 基于异基因癌细胞的免疫治疗 |
WO2009114207A2 (fr) | 2008-03-14 | 2009-09-17 | Sanofi Pasteur Biologics Co. | Vaccins de flavivirus défaillant sur le plan de la réplication et vecteurs de vaccin |
EP2274001A4 (fr) | 2008-03-20 | 2012-08-01 | Univ Miami | Vaccination par protéine de choc thermique gp96 et procédés d'utilisation |
WO2010005474A1 (fr) * | 2008-06-16 | 2010-01-14 | Emergent Product Development Gaithersburg Inc. | Virus de la vaccine ankara (mva) recombinant modifié exprimant des antigènes polypeptidiques de chlamydia |
US20110280895A1 (en) | 2008-11-28 | 2011-11-17 | Riken | IMMUNOTHERAPEUTIC METHOD USING ALLO-CELLS WHICH CO-EXPRESS CD1d AND TARGET ANTIGEN |
DE102008055194A1 (de) | 2008-12-30 | 2010-07-08 | Federal-Mogul Wiesbaden Gmbh | Gleitelement |
WO2010099472A2 (fr) | 2009-02-27 | 2010-09-02 | The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services | Polypeptides spanx-b et leur utilisation |
KR102019728B1 (ko) * | 2009-04-17 | 2019-09-09 | 글로브이뮨 | 암에 대한 병용 면역요법 조성물 및 방법 |
US8961989B2 (en) | 2009-11-20 | 2015-02-24 | Oregon Health & Science University | Methods for producing an immune response to tuberculosis |
ES2625406T3 (es) | 2010-03-25 | 2017-07-19 | Oregon Health & Science University | Glicoproteínas de CMV y vectores recombinantes |
JPWO2011129379A1 (ja) | 2010-04-13 | 2013-07-18 | 独立行政法人理化学研究所 | 新規抗hsp90モノクローナル抗体 |
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CA2807514A1 (fr) | 2010-08-06 | 2012-02-09 | The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services | Biomarqueurs du cancer de la prostate et leurs methodes de detection |
TW201309799A (zh) | 2011-02-15 | 2013-03-01 | Immune Design Corp | 藉由載體化疫苗增強免疫原特異性免疫反應之方法 |
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US11149254B2 (en) | 2011-04-15 | 2021-10-19 | Genelux Corporation | Clonal strains of attenuated vaccinia viruses and methods of use thereof |
HUE037408T2 (hu) | 2011-06-10 | 2018-08-28 | Univ Oregon Health & Science | CMV glikoproteinek és rekombináns vektorok |
CA2789539A1 (fr) | 2011-09-12 | 2013-03-12 | International Aids Vaccine Initiative | Immunoselection de virus de la stomatite vesiculeuse recombinant exprimant des proteines hiv-1 en neutralisant largement les anticorps |
US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
BR112014028476A2 (pt) | 2012-05-16 | 2017-08-01 | Immune Design Corp | fragmento imunogênico de um polipeptídeo, polinucleotídeo isolado, composição farmacêutica imunogênica, métodos para tratar uma infecção, para gerar uma resposta imune em um sujeito, e para imunizar um sujeito |
EP2679596B1 (fr) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | Variante de la protéine env du VIH-1 |
EP2895191B1 (fr) | 2012-09-14 | 2019-06-05 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Protéine brachyury, vecteurs adénoviraux codant pour la protéine brachyury, et leur utilisation |
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US5833975A (en) | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
US5206353A (en) | 1988-07-23 | 1993-04-27 | The United States Of America As Represented By The Department Of Health And Human Services | CD-4/cytotoxic gene fusions |
EP0845537A1 (fr) * | 1989-08-18 | 1998-06-03 | Chiron Corporation | Retrovirus recombinants exprimant une pro-drogue pour le traitement des GVhD |
US5126132A (en) | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
CA2102623C (fr) * | 1991-05-06 | 2003-04-22 | Jeffrey Schlom | Virus recombinant exprimant un antigene carcino-embryonnaire et methodes d'utilisation |
US5342774A (en) | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
WO1994024267A1 (fr) | 1993-04-20 | 1994-10-27 | Robinson, William, S. | Methode et materiel de traitement de patients infectes par des agents infectieux intracellulaires |
US6969609B1 (en) * | 1998-12-09 | 2005-11-29 | The United States Of America As Represented By The Department Of Health And Human Serivces | Recombinant vector expressing multiple costimulatory molecules and uses thereof |
-
1995
- 1995-10-02 WO PCT/US1995/012624 patent/WO1996010419A2/fr active IP Right Grant
- 1995-10-02 AT AT95935264T patent/ATE197765T1/de active
- 1995-10-02 DE DE69519521T patent/DE69519521T2/de not_active Expired - Lifetime
- 1995-10-02 EP EP95935264A patent/EP0784483B1/fr not_active Expired - Lifetime
- 1995-10-02 EP EP00102998A patent/EP1016418B1/fr not_active Expired - Lifetime
- 1995-10-02 AU AU37353/95A patent/AU688606B2/en not_active Expired
- 1995-10-02 CA CA002201587A patent/CA2201587C/fr not_active Expired - Lifetime
- 1995-10-02 ES ES95935264T patent/ES2154738T3/es not_active Expired - Lifetime
- 1995-10-02 PT PT95935264T patent/PT784483E/pt unknown
- 1995-10-02 JP JP51210096A patent/JP3907698B2/ja not_active Expired - Lifetime
- 1995-10-02 DK DK95935264T patent/DK0784483T3/da active
-
2000
- 2000-01-07 US US09/480,340 patent/US6548068B1/en not_active Expired - Lifetime
-
2001
- 2001-02-22 GR GR20010400292T patent/GR3035458T3/el unknown
-
2003
- 2003-01-14 US US10/341,431 patent/US6893869B2/en not_active Expired - Lifetime
-
2004
- 2004-01-23 JP JP2004048693A patent/JP4078319B2/ja not_active Expired - Lifetime
-
2005
- 2005-03-28 US US11/090,686 patent/US7368116B2/en not_active Expired - Lifetime
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- 2006-10-26 JP JP2006291632A patent/JP4160612B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0784483A2 (fr) | 1997-07-23 |
PT784483E (pt) | 2001-05-31 |
JP4160612B2 (ja) | 2008-10-01 |
ATE197765T1 (de) | 2000-12-15 |
EP1016418A3 (fr) | 2004-03-03 |
US6893869B2 (en) | 2005-05-17 |
JP2004222726A (ja) | 2004-08-12 |
US7368116B2 (en) | 2008-05-06 |
AU688606B2 (en) | 1998-03-12 |
WO1996010419A2 (fr) | 1996-04-11 |
GR3035458T3 (en) | 2001-05-31 |
JP4078319B2 (ja) | 2008-04-23 |
US20050186180A1 (en) | 2005-08-25 |
JP3907698B2 (ja) | 2007-04-18 |
EP0784483B1 (fr) | 2000-11-29 |
US6548068B1 (en) | 2003-04-15 |
DE69519521D1 (de) | 2001-01-04 |
JPH10506902A (ja) | 1998-07-07 |
DE69519521T2 (de) | 2001-06-28 |
ES2154738T3 (es) | 2001-04-16 |
JP2007105045A (ja) | 2007-04-26 |
CA2201587C (fr) | 2002-06-25 |
EP1016418B1 (fr) | 2009-12-30 |
AU3735395A (en) | 1996-04-26 |
US20050063993A1 (en) | 2005-03-24 |
WO1996010419A3 (fr) | 1996-05-17 |
CA2201587A1 (fr) | 1996-04-11 |
EP1016418A2 (fr) | 2000-07-05 |
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