DK0773936T3 - Makrocykliske chelatdannende stoffer, deres chelater og anvendelse inden for det diagnostiske område - Google Patents

Makrocykliske chelatdannende stoffer, deres chelater og anvendelse inden for det diagnostiske område

Info

Publication number
DK0773936T3
DK0773936T3 DK95928457T DK95928457T DK0773936T3 DK 0773936 T3 DK0773936 T3 DK 0773936T3 DK 95928457 T DK95928457 T DK 95928457T DK 95928457 T DK95928457 T DK 95928457T DK 0773936 T3 DK0773936 T3 DK 0773936T3
Authority
DK
Denmark
Prior art keywords
chelates
chelating agents
diagnostic field
macrocyclic chelating
metal ions
Prior art date
Application number
DK95928457T
Other languages
English (en)
Inventor
Fulvio Uggeri
Pier Lucio Anelli
Marino Brocchetta
Franco Fedeli
Giuseppe Manfredi
Original Assignee
Bracco Spa
Dibra Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa, Dibra Spa filed Critical Bracco Spa
Application granted granted Critical
Publication of DK0773936T3 publication Critical patent/DK0773936T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95928457T 1994-07-29 1995-07-24 Makrocykliske chelatdannende stoffer, deres chelater og anvendelse inden for det diagnostiske område DK0773936T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941646A IT1274038B (it) 1994-07-29 1994-07-29 Chelanti macrociclici loro chelati e relativi usi in campo diagnostico
PCT/EP1995/002931 WO1996004259A1 (en) 1994-07-29 1995-07-24 Macrocyclic chelants, their chelates and uses thereof in the diagnostic field

Publications (1)

Publication Number Publication Date
DK0773936T3 true DK0773936T3 (da) 1999-04-06

Family

ID=11369406

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95928457T DK0773936T3 (da) 1994-07-29 1995-07-24 Makrocykliske chelatdannende stoffer, deres chelater og anvendelse inden for det diagnostiske område

Country Status (21)

Country Link
US (2) US5622688A (da)
EP (1) EP0773936B1 (da)
JP (1) JP2941062B2 (da)
KR (1) KR100376950B1 (da)
CN (1) CN1064355C (da)
AT (1) ATE167477T1 (da)
AU (1) AU691024B2 (da)
BR (1) BR9508435A (da)
CA (1) CA2196041A1 (da)
DE (2) DE69503055T2 (da)
DK (1) DK0773936T3 (da)
ES (1) ES2100827T3 (da)
FI (1) FI970327A (da)
GR (1) GR970300019T1 (da)
HU (1) HUT76805A (da)
IL (1) IL114732A0 (da)
IT (1) IT1274038B (da)
MX (1) MX9700674A (da)
NO (1) NO307214B1 (da)
WO (1) WO1996004259A1 (da)
ZA (1) ZA956174B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1274038B (it) * 1994-07-29 1997-07-14 Bracco Spa Chelanti macrociclici loro chelati e relativi usi in campo diagnostico
DE69721250T2 (de) * 1996-12-23 2004-02-19 Bracco Research S.A. Zusammensetzungen zur kontrasterhöhung in der kernspin-tomographie für untersuchungen des verdauungstraktes von patienten
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
FR2772025B1 (fr) * 1997-12-10 2000-03-03 Guerbet Sa Chelates metalliques de macrocycles polyaminocarboxyliques et leur application a l'imagerie par resonance magnetique
AU3225900A (en) * 1999-02-09 2000-08-29 Board Of Regents, The University Of Texas System Ph sensitive mri contrast agents
US20020146371A1 (en) * 2000-10-18 2002-10-10 Li King Chuen Methods for development and use of diagnostic and therapeutic agents
EP1326523A4 (en) * 2000-10-19 2005-01-05 Gen Hospital Corp VISUALIZATION OF THE ENZYMATIC ACTIVITY
US20030100829A1 (en) * 2001-11-27 2003-05-29 Sheng-Ping Zhong Medical devices with magnetic resonance visibility enhancing material
US20040215240A1 (en) * 2003-04-11 2004-10-28 Lovett Eric G. Reconfigurable subcutaneous cardiac device
FR2857967B1 (fr) * 2003-07-25 2015-04-24 Centre Nat Rech Scient Complexes de lanthanide, leur preparation et leurs utilisations
US20050107838A1 (en) * 2003-09-18 2005-05-19 Lovett Eric G. Subcutaneous cardiac rhythm management with disordered breathing detection and treatment
ATE430146T1 (de) 2004-07-02 2009-05-15 Bracco Imaging Spa Kontrastmittel mit hoher relaxivität zur verwendung in der magnetresonanzbilddarstellung (mri), enthaltend eine chelatbildende gruppe mit polyhydroxylierten substituenten
CN109384737A (zh) * 2017-08-04 2019-02-26 天津科伦药物研究有限公司 一种四氮杂环钇络合物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
IT1224416B (it) * 1987-12-24 1990-10-04 Bracco Ind Chimica Spa Chelanti macrociclici e loro chelati
US5053503A (en) * 1989-02-17 1991-10-01 Centocor Chelating agents
DE4035760A1 (de) * 1990-11-08 1992-05-14 Schering Ag Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
IT1274038B (it) * 1994-07-29 1997-07-14 Bracco Spa Chelanti macrociclici loro chelati e relativi usi in campo diagnostico
GB9504910D0 (en) * 1995-03-10 1995-04-26 Nycomed Imaging As Compounds

Also Published As

Publication number Publication date
CA2196041A1 (en) 1996-02-15
BR9508435A (pt) 1997-12-23
NO307214B1 (no) 2000-02-28
HUT76805A (en) 1997-11-28
AU3221195A (en) 1996-03-04
ITMI941646A0 (it) 1994-07-29
ES2100827T3 (es) 1998-09-16
IT1274038B (it) 1997-07-14
ITMI941646A1 (it) 1996-01-29
FI970327A (fi) 1997-03-25
KR970704713A (ko) 1997-09-06
JPH10503505A (ja) 1998-03-31
US5622688A (en) 1997-04-22
DE69503055D1 (de) 1998-07-23
ATE167477T1 (de) 1998-07-15
NO970342D0 (no) 1997-01-27
JP2941062B2 (ja) 1999-08-25
ZA956174B (en) 1996-03-07
EP0773936B1 (en) 1998-06-17
NO970342L (no) 1997-04-01
ES2100827T1 (es) 1997-07-01
IL114732A0 (en) 1995-11-27
DE773936T1 (de) 1997-09-25
WO1996004259A1 (en) 1996-02-15
MX9700674A (es) 1997-04-30
DE69503055T2 (de) 1998-10-15
US5708166A (en) 1998-01-13
GR970300019T1 (en) 1997-07-30
CN1064355C (zh) 2001-04-11
KR100376950B1 (ko) 2003-07-16
CN1154108A (zh) 1997-07-09
FI970327A0 (fi) 1997-01-27
AU691024B2 (en) 1998-05-07
EP0773936A1 (en) 1997-05-21

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