DK0758883T3 - Fusogene liposomer og fremgangsmåder til fremstilling af og anvendelse af disse - Google Patents
Fusogene liposomer og fremgangsmåder til fremstilling af og anvendelse af disseInfo
- Publication number
- DK0758883T3 DK0758883T3 DK94919976T DK94919976T DK0758883T3 DK 0758883 T3 DK0758883 T3 DK 0758883T3 DK 94919976 T DK94919976 T DK 94919976T DK 94919976 T DK94919976 T DK 94919976T DK 0758883 T3 DK0758883 T3 DK 0758883T3
- Authority
- DK
- Denmark
- Prior art keywords
- lipid
- outermost
- lipid bilayer
- liposome
- bilayer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1994/003996 WO1995027478A1 (en) | 1994-04-12 | 1994-04-12 | Fusogenic liposomes and methods of making and using same |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0758883T3 true DK0758883T3 (da) | 2003-06-02 |
Family
ID=22242444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94919976T DK0758883T3 (da) | 1994-04-12 | 1994-04-12 | Fusogene liposomer og fremgangsmåder til fremstilling af og anvendelse af disse |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0758883B1 (da) |
JP (1) | JP3804025B2 (da) |
KR (1) | KR100315132B1 (da) |
AT (1) | ATE234605T1 (da) |
AU (1) | AU689479B2 (da) |
CA (1) | CA2187748C (da) |
DE (1) | DE69432320T2 (da) |
DK (1) | DK0758883T3 (da) |
ES (1) | ES2196028T3 (da) |
FI (1) | FI964083A0 (da) |
NO (1) | NO318814B1 (da) |
NZ (1) | NZ268146A (da) |
WO (1) | WO1995027478A1 (da) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ336539A (en) * | 1996-10-15 | 2000-09-29 | Liposome Co Inc | Peptide-lipid conjugates, liposomes and liposomal drug delivery |
US6339069B1 (en) | 1996-10-15 | 2002-01-15 | Elan Pharmaceuticalstechnologies, Inc. | Peptide-lipid conjugates, liposomes and lipsomal drug delivery |
US6835395B1 (en) | 1997-05-14 | 2004-12-28 | The University Of British Columbia | Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles |
DE69841002D1 (de) * | 1997-05-14 | 2009-09-03 | Univ British Columbia | Hochwirksame verkapselung von nukleinsäuren in lipidvesikeln |
US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
CA2382611A1 (en) * | 1999-08-27 | 2001-03-08 | Inex Pharmaceuticals Corp. | Compositions for stimulating cytokine secretion and inducing an immune response |
CA2520864A1 (en) | 2003-03-31 | 2004-10-21 | Alza Corporation | Lipid particles having asymmetric lipid coating and method of preparing same |
CN101111306B (zh) | 2005-01-28 | 2010-09-29 | 独立行政法人科学技术振兴机构 | 经脱水缩合反应可发生相转移的分子集合体及其相转移方法 |
EP3494964B1 (en) * | 2007-05-14 | 2021-04-07 | Konica Minolta Holdings, Inc. | Liposome and method for producing liposome |
US9937128B2 (en) * | 2009-08-03 | 2018-04-10 | The University Of North Carolina At Chapel Hill | Liposomes comprising a calcium phosphate-containing precipitate |
TR201901311T4 (tr) | 2009-12-01 | 2019-02-21 | Translate Bio Inc | İnsan genetik hastalıklarında mRNA'nın teslimi için steroid türevi. |
BR112013031553A2 (pt) | 2011-06-08 | 2020-11-10 | Shire Human Genetic Therapies, Inc. | composições, mrna que codifica para uma hgla e seu uso, uso de pelo menos uma molécula de mrna e um veículo de transferência e uso de um mrna que codifica para proteína exógena |
WO2013185067A1 (en) | 2012-06-08 | 2013-12-12 | Shire Human Genetic Therapies, Inc. | Nuclease resistant polynucleotides and uses thereof |
CN105142676B (zh) | 2013-03-14 | 2022-06-28 | 夏尔人类遗传性治疗公司 | Cftr mrna组合物以及相关方法和用途 |
SG11201507425RA (en) | 2013-03-14 | 2015-10-29 | Shire Human Genetic Therapies | Methods for purification of messenger rna |
EP3060258A1 (en) | 2013-10-22 | 2016-08-31 | Shire Human Genetic Therapies, Inc. | Mrna therapy for phenylketonuria |
EP3501605B1 (en) | 2013-10-22 | 2023-06-28 | Translate Bio, Inc. | Mrna therapy for argininosuccinate synthetase deficiency |
JP6571679B2 (ja) | 2014-04-25 | 2019-09-04 | トランスレイト バイオ, インコーポレイテッド | メッセンジャーrnaの精製方法 |
AU2018224326B2 (en) | 2017-02-27 | 2024-01-04 | Translate Bio, Inc. | Novel codon-optimized CFTR mRNA |
MA49138A (fr) | 2017-05-16 | 2020-03-25 | Translate Bio Inc | Traitement de la fibrose kystique par administration d'arnm à codons optimisés codant pour la cftr |
CN112930396B (zh) | 2018-08-24 | 2024-05-24 | 川斯勒佰尔公司 | 用于纯化信使rna的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4946787A (en) * | 1985-01-07 | 1990-08-07 | Syntex (U.S.A.) Inc. | N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
WO1987007530A1 (en) * | 1986-06-16 | 1987-12-17 | The Liposome Company, Inc. | Induction of asymmetry in vesicles |
JPH0395118A (ja) * | 1989-09-07 | 1991-04-19 | Green Cross Corp:The | プロスタグランジン含有脂肪小体製剤 |
DE4013632A1 (de) * | 1990-04-27 | 1991-10-31 | Max Planck Gesellschaft | Liposomen mit positiver ueberschussladung |
US5283185A (en) * | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
-
1994
- 1994-04-12 DE DE69432320T patent/DE69432320T2/de not_active Expired - Fee Related
- 1994-04-12 AU AU70915/94A patent/AU689479B2/en not_active Ceased
- 1994-04-12 KR KR1019960705605A patent/KR100315132B1/ko not_active IP Right Cessation
- 1994-04-12 AT AT94919976T patent/ATE234605T1/de not_active IP Right Cessation
- 1994-04-12 CA CA002187748A patent/CA2187748C/en not_active Expired - Fee Related
- 1994-04-12 DK DK94919976T patent/DK0758883T3/da active
- 1994-04-12 JP JP52630695A patent/JP3804025B2/ja not_active Expired - Fee Related
- 1994-04-12 NZ NZ268146A patent/NZ268146A/en not_active IP Right Cessation
- 1994-04-12 WO PCT/US1994/003996 patent/WO1995027478A1/en active IP Right Grant
- 1994-04-12 EP EP94919976A patent/EP0758883B1/en not_active Expired - Lifetime
- 1994-04-12 ES ES94919976T patent/ES2196028T3/es not_active Expired - Lifetime
-
1996
- 1996-10-09 NO NO19964284A patent/NO318814B1/no unknown
- 1996-10-11 FI FI964083A patent/FI964083A0/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI964083A (fi) | 1996-10-11 |
NO964284D0 (no) | 1996-10-09 |
EP0758883A1 (en) | 1997-02-26 |
AU689479B2 (en) | 1998-04-02 |
DE69432320T2 (de) | 2003-12-04 |
CA2187748C (en) | 2007-04-10 |
ES2196028T3 (es) | 2003-12-16 |
FI964083A0 (fi) | 1996-10-11 |
ATE234605T1 (de) | 2003-04-15 |
DE69432320D1 (de) | 2003-04-24 |
NZ268146A (en) | 1997-10-24 |
EP0758883B1 (en) | 2003-03-19 |
NO964284L (no) | 1996-10-09 |
JPH09511521A (ja) | 1997-11-18 |
KR100315132B1 (ko) | 2002-06-26 |
NO318814B1 (no) | 2005-05-09 |
WO1995027478A1 (en) | 1995-10-19 |
AU7091594A (en) | 1995-10-30 |
CA2187748A1 (en) | 1995-10-19 |
JP3804025B2 (ja) | 2006-08-02 |
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