DK0730664T3 - Nucleinsyreanaloginduceret transkription af dobbeltstrenget DNA - Google Patents

Nucleinsyreanaloginduceret transkription af dobbeltstrenget DNA

Info

Publication number
DK0730664T3
DK0730664T3 DK95901410T DK95901410T DK0730664T3 DK 0730664 T3 DK0730664 T3 DK 0730664T3 DK 95901410 T DK95901410 T DK 95901410T DK 95901410 T DK95901410 T DK 95901410T DK 0730664 T3 DK0730664 T3 DK 0730664T3
Authority
DK
Denmark
Prior art keywords
initiation site
dna
stranded dna
template
double
Prior art date
Application number
DK95901410T
Other languages
English (en)
Inventor
Michael Egholm
Rolf Henrik Berg
Peter Eigil Nielsen
Ole Buchardt
Original Assignee
Buchardt Dorte
Berg Rolf Hendrik
Peter Eigil Nielsen
Michael Egholm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Buchardt Dorte, Berg Rolf Hendrik, Peter Eigil Nielsen, Michael Egholm filed Critical Buchardt Dorte
Application granted granted Critical
Publication of DK0730664T3 publication Critical patent/DK0730664T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
DK95901410T 1993-11-25 1994-11-22 Nucleinsyreanaloginduceret transkription af dobbeltstrenget DNA DK0730664T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9324245A GB2284209A (en) 1993-11-25 1993-11-25 Nucleic acid analogue-induced transcription of RNA from a double-stranded DNA template
PCT/EP1994/003858 WO1995014789A1 (en) 1993-11-25 1994-11-22 Nucleic acid analogue induced transcription of double stranded dna

Publications (1)

Publication Number Publication Date
DK0730664T3 true DK0730664T3 (da) 1999-09-27

Family

ID=10745684

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95901410T DK0730664T3 (da) 1993-11-25 1994-11-22 Nucleinsyreanaloginduceret transkription af dobbeltstrenget DNA

Country Status (10)

Country Link
US (1) US5837459A (da)
EP (1) EP0730664B1 (da)
JP (1) JP3143475B2 (da)
AT (1) ATE176932T1 (da)
CA (1) CA2176746C (da)
DE (1) DE69416692T2 (da)
DK (1) DK0730664T3 (da)
ES (1) ES2133709T3 (da)
GB (1) GB2284209A (da)
WO (1) WO1995014789A1 (da)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770738B1 (en) * 1992-05-22 2004-08-03 Isis Pharmaceuticals, Inc. Higher order structure and binding of peptide nucleic acids
CA2140081C (en) * 1994-01-13 2008-04-01 Dean L. Engelhardt Process, construct and conjugate for producing multiple nucleic acid copies
AU7016096A (en) * 1995-10-20 1997-05-07 Trustees Of Boston University Nucleic acid clamps
US6617422B1 (en) 1997-05-23 2003-09-09 Peter Nielsen Peptide nucleic acid monomers and oligomers
US6989270B1 (en) 1997-10-17 2006-01-24 Mayo Foundation For Medical Education And Research Using polyamide nucleic acid oligomers to engender a biological response
US6723560B2 (en) 1998-10-08 2004-04-20 Mayo Foundation For Medical Education And Research Using polyamide nucleic acid oligomers to engender a biological response
EP1073766A1 (en) 1998-04-29 2001-02-07 Trustees Of Boston University Methods and compositions pertaining to pd-loops
US7981599B1 (en) 1998-07-31 2011-07-19 Boston Probes, Inc. Non-nucleic acid probes, probe sets, methods and kits pertaining to the detection of individual human chromosomes X, Y, 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 16, 17, 18 and 20 as 13/21 as a pair
US20040014644A1 (en) * 2000-03-14 2004-01-22 Vladimir Efimov Oligonucleotide analogues and methods of use for modulating gene expression
CA2402319A1 (en) 2000-03-14 2001-09-20 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
US6962906B2 (en) * 2000-03-14 2005-11-08 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
DK1349958T3 (da) 2000-09-26 2009-09-21 Boston Probes Inc Prober, probesæt, fremgangsmåder og kits til at opnå påvisning, identifikation og/eller tælling af bakterier
CA2425917A1 (en) * 2000-10-13 2002-04-18 Crosslink Genetics Corporation Artificial transcriptional factors and methods of use
WO2002057493A2 (en) * 2000-12-15 2002-07-25 Boston Probes, Inc. Methods for determining organisms
ATE346950T1 (de) 2001-03-09 2006-12-15 Boston Probes Inc Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
ATE527376T1 (de) 2001-05-18 2011-10-15 Boston Probes Inc Pna-sonden, sondensätze, verfahren und kits im zusammenhang mit dem nachweis von candida
WO2003027328A2 (en) * 2001-09-24 2003-04-03 Boston Probes, Inc. Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid
US7045319B2 (en) * 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
EP1487858A4 (en) * 2002-03-21 2006-01-04 Boston Probes Inc PNA OLIGOMERS, OLIGOMER SETS, PROCESSES AND KITS FOR DETECTION OF BACILLUS ANTHRACIS
US20030211509A1 (en) * 2002-03-26 2003-11-13 Wiley Steven R. TNF-delta ligand and uses thereof
JP2006507798A (ja) * 2002-05-17 2006-03-09 アプレラ コーポレイション Listeriaの決定に関するPNAプローブ、プローブセット、方法およびキット
CA2495895A1 (en) 2002-09-08 2004-03-18 Applera Corporation Methods, compositions and libraries pertaining pna dimer and pna oligomer synthesis
AU2003297557B2 (en) * 2002-11-21 2009-02-26 Cellscript, Inc. Methods for using primers that encode one strand of a double-stranded promoter
US20040259132A1 (en) * 2002-11-22 2004-12-23 Henrik Stender Peptide nucleic acid probes for analysis of pseudomonas (sensu stricto)
WO2005042709A2 (en) * 2003-10-29 2005-05-12 Ribomed Biotechnologies, Inc. Compositions, methods and detection technologies for reiterative oligonucleotide synthesis
WO2005111235A2 (en) * 2004-05-04 2005-11-24 Dak Denmark A/S Methods for detecting chromosome aberrations
JP2008522588A (ja) * 2004-12-06 2008-07-03 バイオヴェリス コーポレイション 炭疽菌(Bacillusanthracis)を検出するための方法及び組成物
WO2006081426A2 (en) * 2005-01-28 2006-08-03 Applera Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target dna template
WO2006130872A2 (en) 2005-06-02 2006-12-07 Advandx, Inc. Peptide nucleic acid probes for analysis of microorganisms
EP1920072A2 (en) 2005-07-01 2008-05-14 Dako Denmark A/S In situ hybridization detection method
US20080241838A1 (en) * 2006-12-29 2008-10-02 Applera Corporation, Applied Biosystems Group Methods and systems for detecting nucleic acids
EP2069525A1 (en) * 2006-12-29 2009-06-17 Applied Biosystems, LLC Systems and methods for detecting nucleic acids
WO2009003493A2 (en) 2007-07-03 2009-01-08 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
US8242243B2 (en) 2008-05-15 2012-08-14 Ribomed Biotechnologies, Inc. Methods and reagents for detecting CpG methylation with a methyl CpG binding protein (MBP)
EP3219812B1 (en) 2008-05-27 2020-09-02 Agilent Technologies, Inc. Hybridization compositions and methods
US8211644B2 (en) * 2008-07-13 2012-07-03 Ribomed Biotechnologies, Inc. Molecular beacon-based methods for detection of targets using abscription
WO2010097655A1 (en) 2009-02-26 2010-09-02 Dako Denmark A/S Compositions and methods for rna hybridization applications
RU2011141720A (ru) 2009-03-15 2013-04-27 Рибомед Байотекнолоджиз, Инк. Молекулярное обнаружение, основанное на абскрипции
ES2601237T3 (es) 2009-12-02 2017-02-14 Dako Denmark A/S Composiciones y métodos para realizar hibridaciones sin desnaturalización
WO2011087789A2 (en) 2009-12-22 2011-07-21 Becton, Dickinson And Company Methods for the detection of microorganisms
WO2013046033A1 (en) 2011-09-30 2013-04-04 Dako Denmark A/S Hybridization compositions and methods using formamide
EP3252173A1 (en) 2011-10-21 2017-12-06 Dako Denmark A/S Hybridization compositions and methods
WO2014033314A1 (en) 2012-09-03 2014-03-06 Uab Bioseka Antisense oligonucleotide targeting bacterial glucosyltransferases
WO2014093291A1 (en) 2012-12-10 2014-06-19 Advandx, Inc. Use of probes for mass spectrometric identification of microorganisms or cells and associated conditions of interest
US9777274B2 (en) 2013-03-15 2017-10-03 Techulon Inc. Antisense molecules for treatment of staphylococcus aureus infection
KR20160021076A (ko) 2013-03-15 2016-02-24 테출론 인코포레이티드 스타필로코커스 아우레우스 감염의 치료를 위한 안티센스 분자
LT6214B (lt) 2013-10-07 2015-08-25 Uab "Bioseka" Priešprasminiai oligonukleotidai aterosklerozės ir kardiovaskulinių infekcijų prevencijai
WO2015057998A1 (en) 2013-10-16 2015-04-23 The University Of British Columbia Device for formulating particles at small volumes
AU2016385135B2 (en) 2016-01-06 2022-02-17 The University Of British Columbia Bifurcating mixers and methods of their use and manufacture
WO2018064755A1 (en) 2016-10-03 2018-04-12 Precision Nanosystems Inc. Compositions for transfecting resistant cell types

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340807C (en) * 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
IE65771B1 (en) * 1990-01-25 1995-11-15 Zeneca Ltd Amplification of nucleotide sequences using vectorette units
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
GB9211979D0 (en) * 1992-06-05 1992-07-15 Buchard Ole Uses of nucleic acid analogues

Also Published As

Publication number Publication date
EP0730664A1 (en) 1996-09-11
ATE176932T1 (de) 1999-03-15
WO1995014789A1 (en) 1995-06-01
CA2176746A1 (en) 1995-06-01
GB9324245D0 (en) 1994-01-12
ES2133709T3 (es) 1999-09-16
JPH09503393A (ja) 1997-04-08
GB2284209A (en) 1995-05-31
CA2176746C (en) 2000-08-08
EP0730664B1 (en) 1999-02-24
GB2284209A8 (en) 1995-09-25
DE69416692D1 (de) 1999-04-01
JP3143475B2 (ja) 2001-03-07
DE69416692T2 (de) 1999-08-05
US5837459A (en) 1998-11-17

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