DE69416692T2 - Mittels nukleinsäureanalogs induzierte transkription von doppelsträngiger dna - Google Patents

Mittels nukleinsäureanalogs induzierte transkription von doppelsträngiger dna

Info

Publication number
DE69416692T2
DE69416692T2 DE69416692T DE69416692T DE69416692T2 DE 69416692 T2 DE69416692 T2 DE 69416692T2 DE 69416692 T DE69416692 T DE 69416692T DE 69416692 T DE69416692 T DE 69416692T DE 69416692 T2 DE69416692 T2 DE 69416692T2
Authority
DE
Germany
Prior art keywords
initiation site
dna
stranded dna
double
template
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69416692T
Other languages
English (en)
Other versions
DE69416692D1 (de
Inventor
Rolf Henrik Berg
Michael Egholm
Peter Eigil Nielsen
Ole Buchardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BERG ROLF HENDRIK FREDERICKSBERG DK
BUCHARDT DORTE VAERLOSE DK
EGHOLM MICHAEL LEXINGTON MASS US
Original Assignee
BERG ROLF HENDRIK FREDERICKSBERG DK
BUCHARDT DORTE VAERLOSE DK
EGHOLM MICHAEL LEXINGTON MASS US
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BERG ROLF HENDRIK FREDERICKSBERG DK, BUCHARDT DORTE VAERLOSE DK, EGHOLM MICHAEL LEXINGTON MASS US filed Critical BERG ROLF HENDRIK FREDERICKSBERG DK
Application granted granted Critical
Publication of DE69416692D1 publication Critical patent/DE69416692D1/de
Publication of DE69416692T2 publication Critical patent/DE69416692T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69416692T 1993-11-25 1994-11-22 Mittels nukleinsäureanalogs induzierte transkription von doppelsträngiger dna Expired - Fee Related DE69416692T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9324245A GB2284209A (en) 1993-11-25 1993-11-25 Nucleic acid analogue-induced transcription of RNA from a double-stranded DNA template
PCT/EP1994/003858 WO1995014789A1 (en) 1993-11-25 1994-11-22 Nucleic acid analogue induced transcription of double stranded dna

Publications (2)

Publication Number Publication Date
DE69416692D1 DE69416692D1 (de) 1999-04-01
DE69416692T2 true DE69416692T2 (de) 1999-08-05

Family

ID=10745684

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69416692T Expired - Fee Related DE69416692T2 (de) 1993-11-25 1994-11-22 Mittels nukleinsäureanalogs induzierte transkription von doppelsträngiger dna

Country Status (10)

Country Link
US (1) US5837459A (de)
EP (1) EP0730664B1 (de)
JP (1) JP3143475B2 (de)
AT (1) ATE176932T1 (de)
CA (1) CA2176746C (de)
DE (1) DE69416692T2 (de)
DK (1) DK0730664T3 (de)
ES (1) ES2133709T3 (de)
GB (1) GB2284209A (de)
WO (1) WO1995014789A1 (de)

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US6770738B1 (en) * 1992-05-22 2004-08-03 Isis Pharmaceuticals, Inc. Higher order structure and binding of peptide nucleic acids
CA2140081C (en) * 1994-01-13 2008-04-01 Dean L. Engelhardt Process, construct and conjugate for producing multiple nucleic acid copies
WO1997014793A1 (en) * 1995-10-20 1997-04-24 Trustees Of Boston University Nucleic acid clamps
US6617422B1 (en) 1997-05-23 2003-09-09 Peter Nielsen Peptide nucleic acid monomers and oligomers
US6723560B2 (en) 1998-10-08 2004-04-20 Mayo Foundation For Medical Education And Research Using polyamide nucleic acid oligomers to engender a biological response
US6989270B1 (en) 1997-10-17 2006-01-24 Mayo Foundation For Medical Education And Research Using polyamide nucleic acid oligomers to engender a biological response
EP1073766A1 (de) 1998-04-29 2001-02-07 Trustees Of Boston University Methoden und zusammensetzungen betreffend pd-loops
US7981599B1 (en) 1998-07-31 2011-07-19 Boston Probes, Inc. Non-nucleic acid probes, probe sets, methods and kits pertaining to the detection of individual human chromosomes X, Y, 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 16, 17, 18 and 20 as 13/21 as a pair
US20040014644A1 (en) * 2000-03-14 2004-01-22 Vladimir Efimov Oligonucleotide analogues and methods of use for modulating gene expression
US6962906B2 (en) * 2000-03-14 2005-11-08 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
CA2402319A1 (en) 2000-03-14 2001-09-20 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
US20020090626A1 (en) 2000-09-26 2002-07-11 Hyldig-Nielsen Jens J. Probes, probe sets, methods and kits pertaining to the detection, identification and/or enumeration of bacteria
WO2002031166A2 (en) * 2000-10-13 2002-04-18 Crosslink Genetics Corporation Artificial transcriptional factors and methods of use
US6905824B2 (en) * 2000-12-15 2005-06-14 Boston Probes, Inc. Methods for determining organisms not requiring the separation of fixative or excess probe
JP4408628B2 (ja) 2001-03-09 2010-02-03 ボストン プローブス，インコーポレイテッド 組み合わせオリゴマーならびにそれらの調製のためのライブラリーに適する、方法、キット、および組成物
WO2002095052A2 (en) 2001-05-18 2002-11-28 Boston Probes, Inc. Pna probes, probe sets, methods and kits pertaining to the detection of candida
WO2003027328A2 (en) 2001-09-24 2003-04-03 Boston Probes, Inc. Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid
US7045319B2 (en) * 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
AU2003230717A1 (en) * 2002-03-21 2003-10-08 Boston Probes, Inc. Pna oligomers, oligomers sets, methods and kits pertaining to the detection of bacillus anthracis
US20030211509A1 (en) * 2002-03-26 2003-11-13 Wiley Steven R. TNF-delta ligand and uses thereof
US20040005611A1 (en) * 2002-05-17 2004-01-08 Hyldig-Nielsen Jens J. PNA probes, probe sets, methods and kits pertaining to the determination of Listeria
DE60330182D1 (de) * 2002-09-08 2009-12-31 Applera Corp Festphasengebundene PNA-Dimere und deren Synthese
WO2004048594A2 (en) * 2002-11-21 2004-06-10 Epicentre Technologies Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
US20040259132A1 (en) * 2002-11-22 2004-12-23 Henrik Stender Peptide nucleic acid probes for analysis of pseudomonas (sensu stricto)
US20050214796A1 (en) * 2003-10-29 2005-09-29 Hanna Michelle M Compositions, methods and detection technologies for reiterative oligonucleotide synthesis
US7306916B2 (en) * 2004-05-04 2007-12-11 Dako Denmark A/S Methods for detecting chromosome aberrations
EP1836317A2 (de) * 2004-12-06 2007-09-26 BioVeris Corporation Verfahren und zusammensetzungen zum nachweis von bacillus anthracis
US7700287B2 (en) * 2005-01-28 2010-04-20 Life Technologies Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template
EP1904079A4 (de) 2005-06-02 2009-10-21 Advandx Inc Peptid-nukleinsäure-sonden zur untersuchung von mikroorganismen
US8546309B2 (en) 2005-07-01 2013-10-01 Dako Denmark A/S Monomeric and polymeric linkers useful for conjugating biological molecules and other substances
US20080241838A1 (en) * 2006-12-29 2008-10-02 Applera Corporation, Applied Biosystems Group Methods and systems for detecting nucleic acids
CN101978070A (zh) * 2006-12-29 2011-02-16 应用生物系统公司 检测核酸的系统和方法
EP3620465A1 (de) 2007-07-03 2020-03-11 Dako Denmark A/S Verbesserte verfahren zur herstellung, markierung und verwendung von mhc-multimeren
CA2724343A1 (en) 2008-05-15 2009-11-19 Ribomed Biotechnologies, Inc. Methods and reagents for detecting cpg methylation with a methyl cpg binding protein (mbp)
ES2668555T3 (es) 2008-05-27 2018-05-18 Dako Denmark A/S Composiciones y métodos para la detección de aberraciones cromosómicas con tampones de hibridación novedosos
US8211644B2 (en) * 2008-07-13 2012-07-03 Ribomed Biotechnologies, Inc. Molecular beacon-based methods for detection of targets using abscription
US9303287B2 (en) 2009-02-26 2016-04-05 Dako Denmark A/S Compositions and methods for RNA hybridization applications
JP2012520086A (ja) 2009-03-15 2012-09-06 リボムド バイオテクノロジーズ インク アブスクリプションに基づく分子検出
WO2011067678A2 (en) 2009-12-02 2011-06-09 Matthiesen Steen H Compositions and methods for performing hybridizations with no denaturation
US9404160B2 (en) 2009-12-22 2016-08-02 Becton, Dickinson And Company Methods for the detection of microorganisms
EP2761028A1 (de) 2011-09-30 2014-08-06 Dako Denmark A/S Hybridisierungszusammensetzungen und -verfahren mit formamid
EP2768974B1 (de) 2011-10-21 2017-07-19 Dako Denmark A/S Hybridisierungszusammensetzungen und -verfahren
WO2014033314A1 (en) 2012-09-03 2014-03-06 Uab Bioseka Antisense oligonucleotide targeting bacterial glucosyltransferases
WO2014093291A1 (en) 2012-12-10 2014-06-19 Advandx, Inc. Use of probes for mass spectrometric identification of microorganisms or cells and associated conditions of interest
EP2970976A4 (de) 2013-03-15 2016-11-02 Techulon Inc Antisense-moleküle zur behandlung von staphylococcus-aureus-infektionen
US9777274B2 (en) 2013-03-15 2017-10-03 Techulon Inc. Antisense molecules for treatment of staphylococcus aureus infection
LT6214B (lt) 2013-10-07 2015-08-25 Uab "Bioseka" Priešprasminiai oligonukleotidai aterosklerozės ir kardiovaskulinių infekcijų prevencijai
US10159652B2 (en) 2013-10-16 2018-12-25 The University Of British Columbia Device for formulating particles at small volumes
US10076730B2 (en) 2016-01-06 2018-09-18 The University Of British Columbia Bifurcating mixers and methods of their use and manufacture
US20210284998A1 (en) 2016-10-03 2021-09-16 Precision Nanosystems Inc. Compositions for Transfecting Resistant Cell Types

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340807C (en) * 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
IE65771B1 (en) * 1990-01-25 1995-11-15 Zeneca Ltd Amplification of nucleotide sequences using vectorette units
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
GB9211979D0 (en) * 1992-06-05 1992-07-15 Buchard Ole Uses of nucleic acid analogues

Also Published As

Publication number Publication date
US5837459A (en) 1998-11-17
DK0730664T3 (da) 1999-09-27
WO1995014789A1 (en) 1995-06-01
DE69416692D1 (de) 1999-04-01
EP0730664A1 (de) 1996-09-11
GB2284209A8 (en) 1995-09-25
GB2284209A (en) 1995-05-31
EP0730664B1 (de) 1999-02-24
JPH09503393A (ja) 1997-04-08
CA2176746C (en) 2000-08-08
ES2133709T3 (es) 1999-09-16
JP3143475B2 (ja) 2001-03-07
CA2176746A1 (en) 1995-06-01
GB9324245D0 (en) 1994-01-12
ATE176932T1 (de) 1999-03-15

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee