DK0728148T3 - Forbedrede immunogene sammensætninger mod humant gastrin 17 - Google Patents

Forbedrede immunogene sammensætninger mod humant gastrin 17

Info

Publication number
DK0728148T3
DK0728148T3 DK95902570T DK95902570T DK0728148T3 DK 0728148 T3 DK0728148 T3 DK 0728148T3 DK 95902570 T DK95902570 T DK 95902570T DK 95902570 T DK95902570 T DK 95902570T DK 0728148 T3 DK0728148 T3 DK 0728148T3
Authority
DK
Denmark
Prior art keywords
pro
against human
glu
immunogenic compositions
human gastrin
Prior art date
Application number
DK95902570T
Other languages
Danish (da)
English (en)
Inventor
Philip C Gevas
Stephen Grimes
Stephen L Karr
Dov Michaeli
Robert Scibienski
Original Assignee
Aphton Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aphton Corp filed Critical Aphton Corp
Application granted granted Critical
Publication of DK0728148T3 publication Critical patent/DK0728148T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/843—Digestive system
    • Y10S530/844—Stomach; intestine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK95902570T 1993-11-12 1994-11-10 Forbedrede immunogene sammensætninger mod humant gastrin 17 DK0728148T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/151,219 US5468494A (en) 1993-11-12 1993-11-12 Immunogenic compositions against human gastrin 17
PCT/US1994/013205 WO1995013297A2 (fr) 1993-11-12 1994-11-10 Compositions immunogenes ameliorees agissant contre la gastrine humaine 17

Publications (1)

Publication Number Publication Date
DK0728148T3 true DK0728148T3 (da) 1999-09-27

Family

ID=22537815

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95902570T DK0728148T3 (da) 1993-11-12 1994-11-10 Forbedrede immunogene sammensætninger mod humant gastrin 17

Country Status (10)

Country Link
US (1) US5468494A (fr)
EP (1) EP0728148B1 (fr)
JP (1) JP3694893B2 (fr)
AT (1) ATE177757T1 (fr)
AU (1) AU1179795A (fr)
DE (1) DE69417252T2 (fr)
DK (1) DK0728148T3 (fr)
ES (1) ES2130575T3 (fr)
GR (1) GR3029791T3 (fr)
WO (1) WO1995013297A2 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861510B1 (en) * 1989-01-24 2005-03-01 Aphton Corporation Immunogenic compositions against gastrin peptides
ATE114160T1 (de) * 1989-01-24 1994-12-15 Aphton Corp Immunogenische zusammensetzungen gegen gastrin- peptide.
CA2261433A1 (fr) * 1993-12-09 1995-06-10 Belinda Sanchez Ramirez Composition comprenant un facteur de croissance epidermique autologue
US5688506A (en) * 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
WO1997028821A1 (fr) * 1996-02-08 1997-08-14 Aphton Corp. Procedes immunologiques appliques dans le traitement du cancer du tube digestif
US20040001842A1 (en) * 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
JP2002511066A (ja) * 1997-05-12 2002-04-09 アフトン コーポレーション Ｃｃｋ−ｂ／ガストリン受容体に対する免疫原性組成物および腫瘍の治療方法
EP1076561B1 (fr) * 1998-05-15 2005-03-30 Aphton Corporation Therapie combinee pour le traitement de tumeurs
US20030068326A1 (en) * 1998-05-15 2003-04-10 Aphton Corporation Method for the treatment of gastroesophageal reflux disease
ES2286883T3 (es) * 1998-05-15 2007-12-01 Receptor Biologix, Inc. Prevencion y tratamiento de la hipergastrinemia.
ATE300311T1 (de) * 1998-05-15 2005-08-15 Aphton Corp Vorbereitung eines medikaments zur behandlung von refluxösophagitis
US20020058040A1 (en) * 1999-12-23 2002-05-16 Stephen Grimes Stable immunogenic composition for frozen storage
US6783761B2 (en) 2000-05-05 2004-08-31 Aphton Corporation Chimeric peptide immunogens
EP1372717A2 (fr) * 2001-03-23 2004-01-02 Aphton Corporation Traitement combine du cancer du pancreas
CU22999A1 (es) * 2001-12-04 2004-10-12 Centro Inmunologia Molecular Método de tratamiento de enfermedades malignas e infecciosas crónicas
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
EP1416964A4 (fr) * 2001-07-09 2005-10-12 Aphton Corp Traitement et prevention de maladies cancereuses et precancereuses du foie, du poumon et de l'oesophage
US20040247661A1 (en) * 2002-07-03 2004-12-09 Dov Michaeli Liposomal vaccine
US20050169979A1 (en) * 2002-07-03 2005-08-04 Dov Michaeli Liposomal vaccine
EP1528915A2 (fr) * 2002-07-03 2005-05-11 Aphton Corporation Vaccin liposomal
EP1608984A2 (fr) * 2003-03-28 2005-12-28 Aphton Corporation Dosages immunologiques pour la detection de l'hormone gastrine
CA2580965C (fr) 2004-09-22 2014-04-08 Receptor Biologix, Inc. Anticorps monoclonaux de progastrine
JP5452223B2 (ja) * 2006-07-24 2014-03-26 テトラロジック ファーマシューティカルズ コーポレーション Ｉａｐ阻害剤
EP2214016B1 (fr) * 2007-10-26 2014-09-10 Advanced Life Science Institute, Inc. Anticorps dirigé contre un peptide libérant la pro-gastrine et son utilisation
US9498522B2 (en) * 2008-08-07 2016-11-22 Mercia Pharma Inc. Immunotherapeutic compositions for the treatment of alzheimer'S disease
US8283372B2 (en) 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
CN101797382B (zh) * 2010-03-03 2013-11-20 戚胜美 抗人前胃液素多肽免疫组合物
US8674064B2 (en) 2010-03-03 2014-03-18 Onkologix Ltd Immunogenic compositions against human progastrin peptides
GB201121571D0 (en) 2011-12-15 2012-01-25 Astrimmune Ltd Compounds and uses thereof
CA2912736C (fr) 2013-05-21 2021-09-07 Tyg Oncology Ltd. Composition immunogene de peptides de la gastrine
JP7469225B2 (ja) 2017-06-15 2024-04-16 キャンサー アドヴァンシーズ インク． 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526716A (en) * 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
US4201770A (en) * 1973-05-07 1980-05-06 The Ohio State University Antigenic modification of polypeptides
US4384995A (en) * 1980-01-16 1983-05-24 The Ohio State University Antigenic modification of polypeptides
US4691006A (en) * 1983-03-04 1987-09-01 Ohio State University Antigenic modification of polypeptides
US4069313A (en) * 1974-11-19 1978-01-17 Merck & Co., Inc. Water-in-oil adjuvant composition
US4894443A (en) * 1984-02-08 1990-01-16 Cetus Corporation Toxin conjugates
ATE114160T1 (de) * 1989-01-24 1994-12-15 Aphton Corp Immunogenische zusammensetzungen gegen gastrin- peptide.
US5023077A (en) * 1989-01-24 1991-06-11 Aphton Corporation Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
US5120829A (en) * 1989-03-20 1992-06-09 La Jolla Cancer Research Foundation Hydrophobic attachment site for adhesion peptides
US5256542A (en) * 1992-03-09 1993-10-26 Tanox Biosystems, Inc. Selecting low frequency antigen-specific single B lymphocytes with correction for background noise

Also Published As

Publication number Publication date
WO1995013297A2 (fr) 1995-05-18
EP0728148A1 (fr) 1996-08-28
ES2130575T3 (es) 1999-07-01
DE69417252T2 (de) 1999-07-08
GR3029791T3 (en) 1999-06-30
AU1179795A (en) 1995-05-29
JPH09505056A (ja) 1997-05-20
ATE177757T1 (de) 1999-04-15
WO1995013297A3 (fr) 1995-06-15
JP3694893B2 (ja) 2005-09-14
DE69417252D1 (de) 1999-04-22
EP0728148B1 (fr) 1999-03-17
US5468494A (en) 1995-11-21

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