DK0712838T3 - Acylphenylglycinderivat og forebyggende middel og lægemiddel til sygdomme, der er forårsaget af en forøget kollagenaseaktiv - Google Patents
Acylphenylglycinderivat og forebyggende middel og lægemiddel til sygdomme, der er forårsaget af en forøget kollagenaseaktivInfo
- Publication number
- DK0712838T3 DK0712838T3 DK94923067T DK94923067T DK0712838T3 DK 0712838 T3 DK0712838 T3 DK 0712838T3 DK 94923067 T DK94923067 T DK 94923067T DK 94923067 T DK94923067 T DK 94923067T DK 0712838 T3 DK0712838 T3 DK 0712838T3
- Authority
- DK
- Denmark
- Prior art keywords
- collagenase activity
- diseases caused
- preventative
- drug
- increased collagenase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21812493 | 1993-08-09 | ||
PCT/JP1994/001284 WO1995004715A1 (fr) | 1993-08-09 | 1994-08-03 | Derive d'acylphenylglycine et agent preventif et curatif, concernant des maladies causees par une activite collagenase accrue, contenant un tel compose comme ingredient actif |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0712838T3 true DK0712838T3 (da) | 1999-07-19 |
Family
ID=16715014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94923067T DK0712838T3 (da) | 1993-08-09 | 1994-08-03 | Acylphenylglycinderivat og forebyggende middel og lægemiddel til sygdomme, der er forårsaget af en forøget kollagenaseaktiv |
Country Status (10)
Country | Link |
---|---|
US (1) | US5795891A (ja) |
EP (1) | EP0712838B1 (ja) |
KR (1) | KR100312097B1 (ja) |
CN (1) | CN1038583C (ja) |
AT (1) | ATE172959T1 (ja) |
DE (1) | DE69414396T2 (ja) |
DK (1) | DK0712838T3 (ja) |
ES (1) | ES2123808T3 (ja) |
TW (1) | TW280810B (ja) |
WO (1) | WO1995004715A1 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9501737D0 (en) * | 1994-04-25 | 1995-03-22 | Hoffmann La Roche | Hydroxamic acid derivatives |
US6127427A (en) | 1995-11-23 | 2000-10-03 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
US6462023B1 (en) | 1996-09-10 | 2002-10-08 | British Biotech Pharmaceuticals, Ltd. | Cytostatic agents |
CN1060804C (zh) * | 1997-03-17 | 2001-01-17 | 中国科学院微生物研究所 | Iv型胶原酶特异性人源基因工程抗体 |
WO2001052891A1 (fr) * | 2000-01-20 | 2001-07-26 | Nippon Organon K. K. | Inhibiteurs d'invasion plasmodiale dans des erythrocytes |
US20210393632A1 (en) | 2018-10-04 | 2021-12-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Egfr inhibitors for treating keratodermas |
CN110554118A (zh) * | 2019-10-15 | 2019-12-10 | 宁夏师范学院 | 一种检测尿液中萘酚含量的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743587A (en) * | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
FR2609289B1 (fr) * | 1987-01-06 | 1991-03-29 | Bellon Labor Sa Roger | Nouveaux composes a activite d'inhibiteurs de collagenase, procede pour les preparer et compositions pharmaceutiques contenant ces composes |
AU2228292A (en) * | 1991-06-14 | 1993-01-12 | Research Corporation Technologies, Inc. | Peptide derivatives of collagenase inhibitor |
-
1994
- 1994-08-03 DE DE69414396T patent/DE69414396T2/de not_active Expired - Fee Related
- 1994-08-03 CN CN94193055A patent/CN1038583C/zh not_active Expired - Fee Related
- 1994-08-03 DK DK94923067T patent/DK0712838T3/da active
- 1994-08-03 US US08/596,278 patent/US5795891A/en not_active Expired - Fee Related
- 1994-08-03 AT AT94923067T patent/ATE172959T1/de not_active IP Right Cessation
- 1994-08-03 ES ES94923067T patent/ES2123808T3/es not_active Expired - Lifetime
- 1994-08-03 KR KR1019960700667A patent/KR100312097B1/ko not_active IP Right Cessation
- 1994-08-03 WO PCT/JP1994/001284 patent/WO1995004715A1/ja active IP Right Grant
- 1994-08-03 EP EP94923067A patent/EP0712838B1/en not_active Expired - Lifetime
- 1994-08-09 TW TW083107264A patent/TW280810B/zh active
Also Published As
Publication number | Publication date |
---|---|
CN1133034A (zh) | 1996-10-09 |
EP0712838A4 (en) | 1996-03-19 |
DE69414396D1 (de) | 1998-12-10 |
KR960703843A (ko) | 1996-08-31 |
ATE172959T1 (de) | 1998-11-15 |
KR100312097B1 (ko) | 2002-11-13 |
WO1995004715A1 (fr) | 1995-02-16 |
DE69414396T2 (de) | 1999-07-15 |
CN1038583C (zh) | 1998-06-03 |
TW280810B (ja) | 1996-07-11 |
EP0712838B1 (en) | 1998-11-04 |
US5795891A (en) | 1998-08-18 |
ES2123808T3 (es) | 1999-01-16 |
EP0712838A1 (en) | 1996-05-22 |
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