DK0706796T3 - Dopamingenoptagelsesinhibitorer til behandling af parkinsonisme - Google Patents
Dopamingenoptagelsesinhibitorer til behandling af parkinsonismeInfo
- Publication number
- DK0706796T3 DK0706796T3 DK94914579T DK94914579T DK0706796T3 DK 0706796 T3 DK0706796 T3 DK 0706796T3 DK 94914579 T DK94914579 T DK 94914579T DK 94914579 T DK94914579 T DK 94914579T DK 0706796 T3 DK0706796 T3 DK 0706796T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- reincorporation
- acyl
- alkyl
- parkinsonism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15556493 | 1993-06-25 | ||
| PCT/JP1994/000728 WO1995000149A1 (fr) | 1993-06-25 | 1994-04-28 | Inhibiteur de reincorporation de dopamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0706796T3 true DK0706796T3 (da) | 2001-03-26 |
Family
ID=15608814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94914579T DK0706796T3 (da) | 1993-06-25 | 1994-04-28 | Dopamingenoptagelsesinhibitorer til behandling af parkinsonisme |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5747493A (da) |
| EP (1) | EP0706796B1 (da) |
| JP (1) | JP3062249B2 (da) |
| KR (1) | KR100307660B1 (da) |
| AT (1) | ATE199318T1 (da) |
| AU (1) | AU674955B2 (da) |
| CA (1) | CA2163986A1 (da) |
| DE (1) | DE69426771T2 (da) |
| DK (1) | DK0706796T3 (da) |
| ES (1) | ES2157258T3 (da) |
| GR (1) | GR3035688T3 (da) |
| PT (1) | PT706796E (da) |
| WO (1) | WO1995000149A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3571114B2 (ja) * | 1995-07-11 | 2004-09-29 | ポーラ化成工業株式会社 | 麻薬拮抗剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1545094A (en) * | 1976-12-14 | 1979-05-02 | Gist Brocades Nv | Piperazine derivatives |
| US4469695A (en) * | 1980-02-25 | 1984-09-04 | Ayerst, Mckenna & Harrison, Inc. | 2-(4-Hydroxyalkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives |
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| CS271571B1 (en) * | 1987-12-10 | 1990-10-12 | Protiva Miroslav | Piperazine derivatives, their salts and method of their preparation |
| CA1340113C (en) * | 1988-05-24 | 1998-11-03 | Magid A. Abou-Gharbia | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
| DE68903263T2 (de) * | 1988-10-10 | 1993-05-19 | Akzo Nv | Substituierte aromatische verbindungen mit zentraler nervensystem-wirkung. |
| US5021421A (en) * | 1989-03-03 | 1991-06-04 | Dainippon Pharmaceutical Co., Ltd. | 2-(1-Piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same |
| JPH0747574B2 (ja) * | 1989-03-03 | 1995-05-24 | 大日本製薬株式会社 | ピリジン誘導体及びそれを有効成分とする向精神剤 |
| TW205034B (da) * | 1990-09-13 | 1993-05-01 | Pola Kasei Kogyo Kk | |
| US5089497A (en) * | 1990-09-20 | 1992-02-18 | Warner-Lambert Company | Substituted piperazines as central nervous system agents |
| CA2067475C (en) * | 1991-05-08 | 2000-10-10 | Yasuo Oshiro | Carbostyril derivatives and their use |
-
1994
- 1994-04-28 ES ES94914579T patent/ES2157258T3/es not_active Expired - Lifetime
- 1994-04-28 DK DK94914579T patent/DK0706796T3/da active
- 1994-04-28 JP JP7502638A patent/JP3062249B2/ja not_active Expired - Fee Related
- 1994-04-28 WO PCT/JP1994/000728 patent/WO1995000149A1/ja active IP Right Grant
- 1994-04-28 DE DE69426771T patent/DE69426771T2/de not_active Expired - Fee Related
- 1994-04-28 AT AT94914579T patent/ATE199318T1/de not_active IP Right Cessation
- 1994-04-28 KR KR1019950705267A patent/KR100307660B1/ko not_active IP Right Cessation
- 1994-04-28 PT PT94914579T patent/PT706796E/pt unknown
- 1994-04-28 CA CA002163986A patent/CA2163986A1/en not_active Abandoned
- 1994-04-28 US US08/557,167 patent/US5747493A/en not_active Expired - Fee Related
- 1994-04-28 EP EP94914579A patent/EP0706796B1/en not_active Expired - Lifetime
- 1994-04-28 AU AU66891/94A patent/AU674955B2/en not_active Ceased
-
2001
- 2001-04-02 GR GR20010400537T patent/GR3035688T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3062249B2 (ja) | 2000-07-10 |
| US5747493A (en) | 1998-05-05 |
| AU6689194A (en) | 1995-01-17 |
| DE69426771D1 (de) | 2001-04-05 |
| PT706796E (pt) | 2001-06-29 |
| CA2163986A1 (en) | 1995-01-05 |
| ATE199318T1 (de) | 2001-03-15 |
| DE69426771T2 (de) | 2001-06-13 |
| EP0706796A1 (en) | 1996-04-17 |
| WO1995000149A1 (fr) | 1995-01-05 |
| ES2157258T3 (es) | 2001-08-16 |
| EP0706796A4 (en) | 1999-03-24 |
| KR100307660B1 (ko) | 2001-12-28 |
| EP0706796B1 (en) | 2001-02-28 |
| KR960702310A (ko) | 1996-04-27 |
| AU674955B2 (en) | 1997-01-16 |
| GR3035688T3 (en) | 2001-07-31 |
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