DE69426771D1 - Dopaminreinkorporationshemmer zur behandlung des parkinsonschen syndroms - Google Patents
Dopaminreinkorporationshemmer zur behandlung des parkinsonschen syndromsInfo
- Publication number
- DE69426771D1 DE69426771D1 DE69426771T DE69426771T DE69426771D1 DE 69426771 D1 DE69426771 D1 DE 69426771D1 DE 69426771 T DE69426771 T DE 69426771T DE 69426771 T DE69426771 T DE 69426771T DE 69426771 D1 DE69426771 D1 DE 69426771D1
- Authority
- DE
- Germany
- Prior art keywords
- syndrome
- treating parkinson
- dopamine
- hydrogen
- reincorporation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Finger-Pressure Massage (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Eye Examination Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15556493 | 1993-06-25 | ||
PCT/JP1994/000728 WO1995000149A1 (fr) | 1993-06-25 | 1994-04-28 | Inhibiteur de reincorporation de dopamine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69426771D1 true DE69426771D1 (de) | 2001-04-05 |
DE69426771T2 DE69426771T2 (de) | 2001-06-13 |
Family
ID=15608814
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69426771T Expired - Fee Related DE69426771T2 (de) | 1993-06-25 | 1994-04-28 | Dopaminreinkorporationshemmer zur behandlung des parkinsonschen syndroms |
Country Status (13)
Country | Link |
---|---|
US (1) | US5747493A (de) |
EP (1) | EP0706796B1 (de) |
JP (1) | JP3062249B2 (de) |
KR (1) | KR100307660B1 (de) |
AT (1) | ATE199318T1 (de) |
AU (1) | AU674955B2 (de) |
CA (1) | CA2163986A1 (de) |
DE (1) | DE69426771T2 (de) |
DK (1) | DK0706796T3 (de) |
ES (1) | ES2157258T3 (de) |
GR (1) | GR3035688T3 (de) |
PT (1) | PT706796E (de) |
WO (1) | WO1995000149A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3571114B2 (ja) * | 1995-07-11 | 2004-09-29 | ポーラ化成工業株式会社 | 麻薬拮抗剤 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1545094A (en) * | 1976-12-14 | 1979-05-02 | Gist Brocades Nv | Piperazine derivatives |
US4469695A (en) * | 1980-02-25 | 1984-09-04 | Ayerst, Mckenna & Harrison, Inc. | 2-(4-Hydroxyalkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives |
IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
CS271571B1 (en) * | 1987-12-10 | 1990-10-12 | Protiva Miroslav | Piperazine derivatives, their salts and method of their preparation |
CA1340113C (en) * | 1988-05-24 | 1998-11-03 | Magid A. Abou-Gharbia | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
ES2052890T3 (es) * | 1988-10-10 | 1994-07-16 | Akzo Nv | Un metodo para la sintesis de compuestos aromaticos di- y trisubstituidos. |
DE69010232T2 (de) * | 1989-03-03 | 1994-12-01 | Dainippon Pharmaceutical Co | 2-(1-Piperazinyl)-4-phenylcycloalkanpyridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten. |
JPH0747574B2 (ja) * | 1989-03-03 | 1995-05-24 | 大日本製薬株式会社 | ピリジン誘導体及びそれを有効成分とする向精神剤 |
TW205034B (de) * | 1990-09-13 | 1993-05-01 | Pola Kasei Kogyo Kk | |
US5089497A (en) * | 1990-09-20 | 1992-02-18 | Warner-Lambert Company | Substituted piperazines as central nervous system agents |
CA2067475C (en) * | 1991-05-08 | 2000-10-10 | Yasuo Oshiro | Carbostyril derivatives and their use |
-
1994
- 1994-04-28 US US08/557,167 patent/US5747493A/en not_active Expired - Fee Related
- 1994-04-28 ES ES94914579T patent/ES2157258T3/es not_active Expired - Lifetime
- 1994-04-28 WO PCT/JP1994/000728 patent/WO1995000149A1/ja active IP Right Grant
- 1994-04-28 DK DK94914579T patent/DK0706796T3/da active
- 1994-04-28 AT AT94914579T patent/ATE199318T1/de not_active IP Right Cessation
- 1994-04-28 DE DE69426771T patent/DE69426771T2/de not_active Expired - Fee Related
- 1994-04-28 JP JP7502638A patent/JP3062249B2/ja not_active Expired - Fee Related
- 1994-04-28 CA CA002163986A patent/CA2163986A1/en not_active Abandoned
- 1994-04-28 EP EP94914579A patent/EP0706796B1/de not_active Expired - Lifetime
- 1994-04-28 AU AU66891/94A patent/AU674955B2/en not_active Ceased
- 1994-04-28 PT PT94914579T patent/PT706796E/pt unknown
- 1994-04-28 KR KR1019950705267A patent/KR100307660B1/ko not_active IP Right Cessation
-
2001
- 2001-04-02 GR GR20010400537T patent/GR3035688T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0706796A1 (de) | 1996-04-17 |
PT706796E (pt) | 2001-06-29 |
CA2163986A1 (en) | 1995-01-05 |
KR100307660B1 (ko) | 2001-12-28 |
EP0706796B1 (de) | 2001-02-28 |
DE69426771T2 (de) | 2001-06-13 |
KR960702310A (ko) | 1996-04-27 |
ATE199318T1 (de) | 2001-03-15 |
AU674955B2 (en) | 1997-01-16 |
GR3035688T3 (en) | 2001-07-31 |
JP3062249B2 (ja) | 2000-07-10 |
AU6689194A (en) | 1995-01-17 |
EP0706796A4 (de) | 1999-03-24 |
ES2157258T3 (es) | 2001-08-16 |
US5747493A (en) | 1998-05-05 |
WO1995000149A1 (fr) | 1995-01-05 |
DK0706796T3 (da) | 2001-03-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1111951T1 (el) | Φαινυλο-καρβοξαμιδικες ενωσεις χρησιμες για την αντιμετωπιση πονου | |
ES2150489T3 (es) | 1-amidinofenil-pirrolidonas, -piperidinonas, -azetinonas como inhibidores de la agregacion de plaquetas. | |
DK0638071T3 (da) | Heterocykliske carboxylsyrederivater, der bindes til retenoidreceptorer (RAR) | |
HK1074794A1 (en) | The use of substituted cyanopyrrolidines for treating hyperlipidemia | |
DE68914292D1 (de) | Zusammensetzung zur Behandlung von ischämischen Störungen in Organen. | |
EA200000614A1 (ru) | 2,3-замещенные соединения индола в качестве ингибиторов сох-2 | |
ATE247089T1 (de) | Pyridoncarbonsäurederivate oder ihre salze und diese als aktive bestandteile enthaltende medikamente | |
DK0453042T3 (da) | Hidtil ukendte 2 9-disubstituerede 4H-pyhrido[1 2-a]pyridin-4-oner | |
DE69326395T2 (de) | Spirooxathiolan-quinuclidin-Derivat zur Behandlung des Sjögren-Syndroms | |
DE69202166D1 (de) | Verwendung von Tetrahydrothienopyridinderivate als Angiogenese-Inhibitoren. | |
PT1080081E (pt) | Derivados do benzofuraxano e a sua utilizacao no tratamento da angina de peito | |
EP0546177A4 (de) | Benzopyran derivat, seine darstellung und pharmazeutische zusammensetzung, welche dieses enthält. | |
FI935799A0 (fi) | Arylsubstituerade heterocykliska foereningar | |
DE69426771T2 (de) | Dopaminreinkorporationshemmer zur behandlung des parkinsonschen syndroms | |
DK1174131T3 (da) | Anvendelse af et middel til forbedring af astrocytfunktion til behandling af Parkinsons sygdom | |
FI935798A0 (fi) | Alkylsubstituerade heterocykliska foereningar | |
MY143862A (en) | Piperidine-substituted indoles-or heteroderivatives thereof | |
ES2168119T3 (es) | Derivados de quinoxalina para el tratamiento de tinnitus. | |
DK0660840T3 (da) | Phosphono-substituerede tetrazolderivater. | |
DE3884878T2 (de) | Uricosuretische Zusammensetzung. | |
BR9206978A (pt) | Composição farmacêutica para inibir infecção com vírus da aids | |
TH23895A (th) | ซับสทิทิวเทด 2-เฟนิลพิริดีน |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |