ATE247089T1 - Pyridoncarbonsäurederivate oder ihre salze und diese als aktive bestandteile enthaltende medikamente - Google Patents

Pyridoncarbonsäurederivate oder ihre salze und diese als aktive bestandteile enthaltende medikamente

Info

Publication number
ATE247089T1
ATE247089T1 AT97946800T AT97946800T ATE247089T1 AT E247089 T1 ATE247089 T1 AT E247089T1 AT 97946800 T AT97946800 T AT 97946800T AT 97946800 T AT97946800 T AT 97946800T AT E247089 T1 ATE247089 T1 AT E247089T1
Authority
AT
Austria
Prior art keywords
group
amino
salts
substituted
halogen atom
Prior art date
Application number
AT97946800T
Other languages
English (en)
Inventor
Nobuya Sakae
Akira Yazaki
Yasuhiro Kuramoto
Jiro Yoshida
Yoshiko Niino
Yoshihiro Oshita
Yuzo Hirao
Norihiro Hayashi
Hirotaka Amano
Original Assignee
Wakunaga Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakunaga Pharma Co Ltd filed Critical Wakunaga Pharma Co Ltd
Application granted granted Critical
Publication of ATE247089T1 publication Critical patent/ATE247089T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AT97946800T 1996-11-28 1997-11-27 Pyridoncarbonsäurederivate oder ihre salze und diese als aktive bestandteile enthaltende medikamente ATE247089T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP31769396 1996-11-28
JP16724597 1997-06-24
PCT/JP1997/004326 WO1998023592A1 (fr) 1996-11-28 1997-11-27 Nouveaux derives d'acide pyridonecarboxylique ou leurs sels, et medicaments contenant ceux-ci en tant que principe actif

Publications (1)

Publication Number Publication Date
ATE247089T1 true ATE247089T1 (de) 2003-08-15

Family

ID=26491349

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97946800T ATE247089T1 (de) 1996-11-28 1997-11-27 Pyridoncarbonsäurederivate oder ihre salze und diese als aktive bestandteile enthaltende medikamente

Country Status (8)

Country Link
US (1) US6136823A (de)
EP (1) EP0945435B1 (de)
JP (1) JP3448305B2 (de)
KR (1) KR100516379B1 (de)
AT (1) ATE247089T1 (de)
CA (1) CA2271136C (de)
DE (1) DE69724140T2 (de)
WO (1) WO1998023592A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK285814B6 (sk) * 1999-07-01 2007-08-02 Wakunaga Pharmaceutical Co., Ltd. Kyselina 1-(6-amino-3,5-difluoropyridín-2-yl)-8-bromo-7-(3- etylaminoazetidín-1-yl)-6-fluoro-4-oxo-1,4-dihydrochinolín-3- karboxylová alebo jej soľ, farmaceutický prostriedok s jej obsahom a jej použitie
PE20011349A1 (es) 2000-06-16 2002-01-19 Upjohn Co 1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US20030232059A1 (en) * 2002-06-18 2003-12-18 Ling Yuk Cheung Feed additives for fishes
KR20060041254A (ko) * 2003-07-24 2006-05-11 아스텔라스세이야쿠 가부시키가이샤 퀴놀론 유도체 또는 그의 염
JP4858683B2 (ja) * 2005-01-20 2012-01-18 アステラス製薬株式会社 キノロン誘導体又はその塩の製造法
JP4853824B2 (ja) * 2005-01-20 2012-01-11 アステラス製薬株式会社 キノロン誘導体を有効成分とする医薬組成物
JO2323B1 (en) * 2005-05-12 2006-06-28 الجامعة الأردنية Compounds of Pyrido [f-3,2] quinoxaline-8-carboxylic acid and its equivalents of pyrido [g-3,2] quinoxalin.
PT2383271E (pt) * 2006-03-13 2013-10-10 Kyorin Seiyaku Kk Aminoquinolonas como inibidores de gsk-3
TWI391378B (zh) 2006-03-16 2013-04-01 Astellas Pharma Inc 喹啉酮衍生物或其製藥學上可被容許之鹽
GB2442951B (en) * 2006-08-10 2011-02-23 Univ Jordan Anticancer and antibacterial agents
US8389514B2 (en) 2007-09-11 2013-03-05 Kyorin Pharmaceutical Co., Ltd. Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors
CN101855229A (zh) 2007-09-12 2010-10-06 埃迪威克斯生物科学公司 作为gsk-3抑制剂的螺环状氨基喹诺酮
US8071591B2 (en) 2009-03-11 2011-12-06 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones as GSK-3 inhibitors
CN106256824B (zh) * 2015-06-18 2020-10-27 重庆医药工业研究院有限责任公司 一种高纯度德拉沙星葡甲胺盐的制备方法
WO2018011017A1 (de) 2016-07-11 2018-01-18 Bayer Pharma Aktiengesellschaft 7-substituierte 1-pyridyl-naphthyridin-3-carbonsäureamide und ihre verwendung
JOP20190045A1 (ar) 2016-09-14 2019-03-14 Bayer Ag مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها.
EP3296298A1 (de) 2016-09-14 2018-03-21 Bayer Pharma Aktiengesellschaft 7-substituierte 1-aryl-naphthyridin-3-carbonsäureamide und ihre verwendung
JOP20190086A1 (ar) 2016-10-21 2019-04-18 Novartis Ag مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
WO2018107112A1 (en) 2016-12-09 2018-06-14 University Of Iowa Research Foundation Quinolone-based compounds with anticancer activity
CN114539213A (zh) * 2021-08-18 2022-05-27 广东工业大学 一种氟喹诺酮类化合物及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774246A (en) * 1984-01-26 1988-09-27 Abbott Laboratories Quinoline antibacterial compounds
JPS60163866A (ja) * 1984-01-26 1985-08-26 アボツト　ラボラトリーズ キノリン系抗菌性化合物
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
GB8524662D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinolone compounds
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
JPH0348682A (ja) * 1989-07-14 1991-03-01 Yoshitomi Pharmaceut Ind Ltd ピリドンカルボン酸化合物
DE3934082A1 (de) * 1989-10-12 1991-04-18 Bayer Ag Chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung als antivirale mittel
CA2247018A1 (en) * 1996-02-27 1997-09-04 Dainippon Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives and intermediates for the synthesis thereof
WO1997040036A1 (fr) * 1996-04-19 1997-10-30 Wakunaga Pharmaceutical Co., Ltd. Nouveaux derives de l'acide pyridonocarboxylique ou des sels de cet acide et agents antibacteriens contenant ces substances en tant que composant actif

Also Published As

Publication number Publication date
EP0945435A4 (de) 1999-12-15
CA2271136C (en) 2008-11-25
DE69724140T2 (de) 2004-06-03
KR20000053224A (ko) 2000-08-25
CA2271136A1 (en) 1998-06-04
JP3448305B2 (ja) 2003-09-22
EP0945435A1 (de) 1999-09-29
WO1998023592A1 (fr) 1998-06-04
DE69724140D1 (de) 2003-09-18
US6136823A (en) 2000-10-24
EP0945435B1 (de) 2003-08-13
KR100516379B1 (ko) 2005-09-26

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