DK0683665T3 - Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse - Google Patents
Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelseInfo
- Publication number
- DK0683665T3 DK0683665T3 DK94908636T DK94908636T DK0683665T3 DK 0683665 T3 DK0683665 T3 DK 0683665T3 DK 94908636 T DK94908636 T DK 94908636T DK 94908636 T DK94908636 T DK 94908636T DK 0683665 T3 DK0683665 T3 DK 0683665T3
- Authority
- DK
- Denmark
- Prior art keywords
- biologically active
- particles
- methods
- active substances
- carrier
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000013543 active substance Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229940088623 biologically active substance Drugs 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 239000000320 mechanical mixture Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1136393A | 1993-01-29 | 1993-01-29 | |
PCT/US1994/000892 WO1994016683A1 (en) | 1993-01-29 | 1994-01-26 | Magnetically responsive composition for carrying biologically active substances and methods of production and use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0683665T3 true DK0683665T3 (da) | 2002-04-02 |
Family
ID=21750068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94908636T DK0683665T3 (da) | 1993-01-29 | 1994-01-26 | Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse |
Country Status (12)
Country | Link |
---|---|
US (3) | US5549915A (da) |
EP (1) | EP0683665B1 (da) |
JP (2) | JP3145120B2 (da) |
AT (1) | ATE210967T1 (da) |
AU (1) | AU6165394A (da) |
CA (1) | CA2154913C (da) |
DE (1) | DE69429507T2 (da) |
DK (1) | DK0683665T3 (da) |
ES (1) | ES2165385T3 (da) |
HK (1) | HK1013256A1 (da) |
PT (1) | PT683665E (da) |
WO (1) | WO1994016683A1 (da) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6200547B1 (en) | 1994-01-26 | 2001-03-13 | Ferx Incorporated | Magnetically responsive compositions for carrying biologically active substances and methods of production and use |
EP0683665B1 (en) * | 1993-01-29 | 2001-12-19 | Ferx Incorporated | Magnetically responsive composition for carrying biologically active substances and methods of production and use |
US6482436B1 (en) | 1993-01-29 | 2002-11-19 | Ferx Incorporated | Magnetically responsive composition |
US5958458A (en) * | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
US6368586B1 (en) | 1996-01-26 | 2002-04-09 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US5985312A (en) * | 1996-01-26 | 1999-11-16 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
US6488615B1 (en) | 2000-03-31 | 2002-12-03 | Ferx Incorporated | Permanent magnet keeper-shield assembly |
US7090636B2 (en) * | 2000-03-31 | 2006-08-15 | Fe Rx Incorporated | Permanent magnet keeper-shield assembly |
WO2002069351A1 (en) * | 2001-02-26 | 2002-09-06 | University Of Utah Research Foundation | Magnetic activated carbon particles for adsorption of solutes from solution |
US6921283B2 (en) * | 2001-08-27 | 2005-07-26 | Trompeter Electronics, Inc. | BNC connector having visual indication |
FR2832598B1 (fr) * | 2001-11-26 | 2006-01-27 | Oreal | Article de conditionnement et/ou d'application d'un produit |
AU2003214812A1 (en) * | 2002-01-09 | 2003-07-30 | Ferx Incorporated | Magnetic delivery compositions |
EP1482956A1 (en) * | 2002-02-01 | 2004-12-08 | Vanderbilt University | Targeted drug delivery methods |
US8097185B2 (en) * | 2002-02-26 | 2012-01-17 | University Of Utah Research Foundation | Magnetic activated carbon particles for adsorption of solutes from solution |
WO2004066975A1 (en) * | 2002-12-18 | 2004-08-12 | Hough Ear Institute | Otologic nanotechnology |
US8651113B2 (en) * | 2003-06-18 | 2014-02-18 | Swr&D Inc. | Magnetically responsive nanoparticle therapeutic constructs and methods of making and using |
US7723311B2 (en) * | 2003-06-18 | 2010-05-25 | Nanobiomagnetics, Inc. | Delivery of bioactive substances to target cells |
US7344491B1 (en) | 2003-11-26 | 2008-03-18 | Nanobiomagnetics, Inc. | Method and apparatus for improving hearing |
ES2264839B1 (es) * | 2003-11-24 | 2007-10-01 | Universidad De Zaragoza (Inst Denanociencia De Ar Agom. | Farmacoterapia parenteral focalizada mediante el implante de imanes permanentes en los organos diana. |
DE10359252A1 (de) * | 2003-12-17 | 2005-07-28 | Siemens Ag | Navigierte Wärmebehandlung von Tumoren mit enzymumhüllten Eisenpartikeln |
US20070100457A1 (en) * | 2004-03-04 | 2007-05-03 | Hyde Edward R Jr | Paramagnetic liquid interface |
CN1976681A (zh) * | 2004-03-26 | 2007-06-06 | 弗尔克斯破产财产公司 | 可磁性靶向丝裂霉素c组合物及其使用方法 |
US20060024378A1 (en) * | 2004-08-02 | 2006-02-02 | Mehta Rakesh H | Magnetically responsive carbon nano-structures for transporting biologically active substances, and methods relating thereto |
US20070281007A1 (en) * | 2004-08-27 | 2007-12-06 | Jacob Jules S | Mucoadhesive Oral Formulations of High Permeability, High Solubility Drugs |
US8568286B2 (en) * | 2006-06-14 | 2013-10-29 | Cardiac Pacemakers, Inc. | Methods to position therapeutic agents using a magnetic field |
EP2444912A3 (en) * | 2006-06-28 | 2012-07-25 | IHI Corporation | Magnetic drug, magnetic drug guidance system and magnetic drug design method |
US20080097606A1 (en) * | 2006-10-19 | 2008-04-24 | Cragg Andrew H | Knee joint prosthesis and hyaluronate compositions for treatment of osteoarthritis |
US20090169484A1 (en) | 2007-12-28 | 2009-07-02 | Ihi Corporation | Iron-salen complex |
JP5433155B2 (ja) * | 2008-02-20 | 2014-03-05 | 株式会社Ihi | 磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置 |
JP2009274962A (ja) * | 2008-05-12 | 2009-11-26 | Yoshihiro Ishikawa | 鉄サレン錯体、磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置 |
CN102239138A (zh) | 2008-11-20 | 2011-11-09 | 株式会社Ihi | 自磁性金属salen络合物 |
WO2011077750A1 (ja) | 2009-12-25 | 2011-06-30 | 株式会社Ihi | 磁石体及び磁石体を用いたドラッグデリバリー制御装置 |
EP2578643B1 (en) | 2010-06-01 | 2019-07-10 | IHI Corporation | Fluorescent dye material and use thereof |
US10398668B2 (en) | 2010-10-19 | 2019-09-03 | The Board Of Regents Of The University Of Oklahoma | Glutamate treatment of cardiovascular disorders |
US8740872B2 (en) | 2010-10-19 | 2014-06-03 | The Board Of Regents Of The University Of Oklahoma | Magnetically-targeted treatment for cardiac disorders |
US9744235B2 (en) | 2010-10-19 | 2017-08-29 | The Board Of Regents Of The University Of Oklahoma | Treatment of cardiovascular disorders with targeted nanoparticles |
JP2012176905A (ja) * | 2011-02-25 | 2012-09-13 | Ihi Corp | 金属サレン錯体化合物 |
JP2012131737A (ja) * | 2010-12-21 | 2012-07-12 | Ihi Corp | 金属サレン錯体化合物及びその製造方法 |
SG192062A1 (en) * | 2010-12-21 | 2013-08-30 | Ihi Corp | Metal-salen complex compound and production method for same |
JP2012167067A (ja) | 2011-02-15 | 2012-09-06 | Ihi Corp | 自己磁性金属サレン錯体化合物 |
JP5873656B2 (ja) | 2011-06-13 | 2016-03-01 | 株式会社Ihi | 金属サレン錯体化合物、局所麻酔薬剤及び抗悪性腫瘍薬剤 |
JP6017766B2 (ja) | 2011-07-26 | 2016-11-02 | 株式会社Ihi | 新規な金属サレン錯体化合物の抗がん剤 |
WO2013051389A1 (ja) | 2011-10-04 | 2013-04-11 | 株式会社Ihi | 金属サレン錯体化合物応答性薬剤及び金属サレン錯体化合物の体内挙動制御システム |
RU2573400C1 (ru) * | 2011-10-06 | 2016-01-20 | АйЭйчАй КОРПОРЕЙШН | Магнитная композиция и способ ее получения |
SG11201702260RA (en) | 2014-09-26 | 2017-04-27 | Ihi Corp | Anti-cancer agent and cancer cell killing method |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3718594A (en) * | 1970-11-30 | 1973-02-27 | Eastman Kodak Co | Method of preparing magnetically responsive carrier particles |
US4106488A (en) * | 1974-08-20 | 1978-08-15 | Robert Thomas Gordon | Cancer treatment method |
US4345588A (en) * | 1979-04-23 | 1982-08-24 | Northwestern University | Method of delivering a therapeutic agent to a target capillary bed |
US4247406A (en) * | 1979-04-23 | 1981-01-27 | Widder Kenneth J | Intravascularly-administrable, magnetically-localizable biodegradable carrier |
US4331654A (en) * | 1980-06-13 | 1982-05-25 | Eli Lilly And Company | Magnetically-localizable, biodegradable lipid microspheres |
WO1983001738A1 (en) * | 1981-11-12 | 1983-05-26 | SCHRÖDER, Ulf | Intravascularly administrable, magnetically responsive nanosphere or manoparticle, a process for the production thereof, and the use thereof |
JPS59122429A (ja) * | 1982-12-28 | 1984-07-14 | Japan Synthetic Rubber Co Ltd | 生物学的物質の担体用磁性粒子 |
US4652257A (en) * | 1985-03-21 | 1987-03-24 | The United States Of America As Represented By The Secretary Of The Navy | Magnetically-localizable, polymerized lipid vesicles and method of disrupting same |
US4849209A (en) * | 1985-06-07 | 1989-07-18 | Cadema Medical Products, Inc. | Treatment of arthritis, including rheumatoid arthritis with 166 Holmium radionuclide |
US4818614A (en) * | 1985-07-29 | 1989-04-04 | Shiseido Company Ltd. | Modified powder |
US4690130A (en) * | 1985-12-19 | 1987-09-01 | Mirell Stuart G | Electromagnetic therapy control system |
US4871716A (en) * | 1986-02-04 | 1989-10-03 | University Of Florida | Magnetically responsive, hydrophilic microspheres for incorporation of therapeutic substances and methods of preparation thereof |
JPH01122037U (da) * | 1988-02-12 | 1989-08-18 | ||
SU1722256A3 (ru) * | 1989-11-02 | 1992-03-23 | Viktor A Volkonskij | Cпocoб пoлучehия maгhиtoупpabляemoй диcпepcии |
EP0683665B1 (en) * | 1993-01-29 | 2001-12-19 | Ferx Incorporated | Magnetically responsive composition for carrying biologically active substances and methods of production and use |
-
1994
- 1994-01-26 EP EP94908636A patent/EP0683665B1/en not_active Expired - Lifetime
- 1994-01-26 PT PT94908636T patent/PT683665E/pt unknown
- 1994-01-26 US US08/188,062 patent/US5549915A/en not_active Expired - Lifetime
- 1994-01-26 DK DK94908636T patent/DK0683665T3/da active
- 1994-01-26 AU AU61653/94A patent/AU6165394A/en not_active Abandoned
- 1994-01-26 ES ES94908636T patent/ES2165385T3/es not_active Expired - Lifetime
- 1994-01-26 AT AT94908636T patent/ATE210967T1/de not_active IP Right Cessation
- 1994-01-26 DE DE69429507T patent/DE69429507T2/de not_active Expired - Fee Related
- 1994-01-26 CA CA002154913A patent/CA2154913C/en not_active Expired - Fee Related
- 1994-01-26 JP JP51728294A patent/JP3145120B2/ja not_active Expired - Fee Related
- 1994-01-26 WO PCT/US1994/000892 patent/WO1994016683A1/en active IP Right Grant
-
1995
- 1995-06-07 US US08/480,195 patent/US5705195A/en not_active Expired - Lifetime
- 1995-06-07 US US08/480,141 patent/US5651989A/en not_active Expired - Lifetime
-
1998
- 1998-12-22 HK HK98114605A patent/HK1013256A1/xx not_active IP Right Cessation
-
2000
- 2000-06-12 JP JP2000175975A patent/JP3176600B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0683665A4 (en) | 1996-04-17 |
US5651989A (en) | 1997-07-29 |
AU6165394A (en) | 1994-08-15 |
JP3145120B2 (ja) | 2001-03-12 |
US5549915A (en) | 1996-08-27 |
ATE210967T1 (de) | 2002-01-15 |
US5705195A (en) | 1998-01-06 |
CA2154913A1 (en) | 1994-08-04 |
JP3176600B2 (ja) | 2001-06-18 |
EP0683665B1 (en) | 2001-12-19 |
DE69429507T2 (de) | 2002-05-16 |
EP0683665A1 (en) | 1995-11-29 |
ES2165385T3 (es) | 2002-03-16 |
JP2001010978A (ja) | 2001-01-16 |
DE69429507D1 (de) | 2002-01-31 |
WO1994016683A1 (en) | 1994-08-04 |
JPH08506111A (ja) | 1996-07-02 |
CA2154913C (en) | 1999-10-19 |
HK1013256A1 (en) | 1999-08-20 |
PT683665E (pt) | 2002-05-31 |
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