DK0682256T3 - Fremgangsmåde til en vivo-påvisning af collagennedbrydning - Google Patents

Fremgangsmåde til en vivo-påvisning af collagennedbrydning

Info

Publication number
DK0682256T3
DK0682256T3 DK95201148T DK95201148T DK0682256T3 DK 0682256 T3 DK0682256 T3 DK 0682256T3 DK 95201148 T DK95201148 T DK 95201148T DK 95201148 T DK95201148 T DK 95201148T DK 0682256 T3 DK0682256 T3 DK 0682256T3
Authority
DK
Denmark
Prior art keywords
vivo detection
collagen degradation
pyridinoline
collagen
whereinis
Prior art date
Application number
DK95201148T
Other languages
English (en)
Inventor
David R Eyre
Original Assignee
Washington Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27034100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0682256(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/444,881 external-priority patent/US5140103A/en
Application filed by Washington Res Found filed Critical Washington Res Found
Application granted granted Critical
Publication of DK0682256T3 publication Critical patent/DK0682256T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/108—Osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95201148T 1989-12-01 1990-11-30 Fremgangsmåde til en vivo-påvisning af collagennedbrydning DK0682256T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/444,881 US5140103A (en) 1987-11-06 1989-12-01 Peptide fragments containing HP and LP cross-links
US07/614,719 US5300434A (en) 1987-11-06 1990-11-21 Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide

Publications (1)

Publication Number Publication Date
DK0682256T3 true DK0682256T3 (da) 2005-02-14

Family

ID=27034100

Family Applications (3)

Application Number Title Priority Date Filing Date
DK91900109.9T DK0502928T3 (da) 1989-12-01 1990-11-30 Fremgangsmåder til detektion af collagennedbrydning in vivo
DK95201176T DK0682257T3 (da) 1989-12-01 1990-11-30 Fremgangsmåder til detektion af collagennedbrydning in vivo
DK95201148T DK0682256T3 (da) 1989-12-01 1990-11-30 Fremgangsmåde til en vivo-påvisning af collagennedbrydning

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK91900109.9T DK0502928T3 (da) 1989-12-01 1990-11-30 Fremgangsmåder til detektion af collagennedbrydning in vivo
DK95201176T DK0682257T3 (da) 1989-12-01 1990-11-30 Fremgangsmåder til detektion af collagennedbrydning in vivo

Country Status (13)

Country Link
US (5) US5300434A (da)
EP (6) EP0890840A3 (da)
JP (6) JP2782017B2 (da)
AT (3) ATE133790T1 (da)
AU (1) AU645049B2 (da)
DE (4) DE69025199T2 (da)
DK (3) DK0502928T3 (da)
ES (2) ES2133656T3 (da)
GR (3) GR940300047T1 (da)
IE (1) IE65280B1 (da)
NO (1) NO309483B1 (da)
RU (1) RU2139541C1 (da)
WO (1) WO1991008478A2 (da)

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US6153732A (en) * 1987-11-06 2000-11-28 Washington Research Foundation Kit for detecting analyte indicative of type II collagen resorption in vivo
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US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
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US5350855A (en) * 1992-09-30 1994-09-27 Metra Biosystems, Inc. Derivatized D-acyl pyridinium reagent
US6132976A (en) * 1992-12-04 2000-10-17 Shriners Hospitals For Children Immunoassays for the measurement of collagen denaturation and cleavage in cartilage
US5736344A (en) * 1992-12-17 1998-04-07 Metra Biosystems, Inc. Serum pyridinium crosslinks assay
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US6030792A (en) * 1997-11-13 2000-02-29 Pfizer Inc Assays for measurement of protein fragments in biological media
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DE69926888T2 (de) * 1998-06-19 2006-03-30 Washington Research Foundation, Seattle Knorpelresorptionsassays
US6348320B1 (en) * 1998-06-19 2002-02-19 Washington Research Foundation Cartilage resorption assays measuring type II collagen fragments
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US5320970A (en) * 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
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Also Published As

Publication number Publication date
AU6889891A (en) 1991-06-26
US5300434A (en) 1994-04-05
JP2999416B2 (ja) 2000-01-17
US5656439A (en) 1997-08-12
EP1560026A1 (en) 2005-08-03
JP2782017B2 (ja) 1998-07-30
US5473052A (en) 1995-12-05
US5677198A (en) 1997-10-14
ES2061422T3 (es) 1996-03-16
JPH05502223A (ja) 1993-04-22
EP0502928A1 (en) 1992-09-16
EP0890840A2 (en) 1999-01-13
EP0682257B1 (en) 1999-04-28
JPH10260183A (ja) 1998-09-29
DE69025199T2 (de) 1996-05-30
EP0682256A1 (en) 1995-11-15
GR940300047T1 (en) 1994-07-29
JP2002139492A (ja) 2002-05-17
JP2000055915A (ja) 2000-02-25
ES2133656T3 (es) 1999-09-16
DE69034170D1 (de) 2004-11-18
JP2999444B2 (ja) 2000-01-17
ATE179521T1 (de) 1999-05-15
EP0682256B1 (en) 2004-10-13
EP0682257A1 (en) 1995-11-15
ATE279730T1 (de) 2004-10-15
RU2139541C1 (ru) 1999-10-10
WO1991008478A2 (en) 1991-06-13
NO922149L (no) 1992-07-29
AU645049B2 (en) 1994-01-06
GR3030646T3 (en) 1999-10-29
EP0502928B1 (en) 1996-01-31
DE69033082D1 (de) 1999-06-02
DK0502928T3 (da) 1996-02-19
IE65280B1 (en) 1995-10-18
GR3018852T3 (en) 1996-05-31
JP2000050865A (ja) 2000-02-22
ES2061422T1 (es) 1994-12-16
DE69034170T2 (de) 2006-03-02
IE904344A1 (en) 1991-06-05
DE69025199D1 (de) 1996-03-14
EP1632502A1 (en) 2006-03-08
NO309483B1 (no) 2001-02-05
EP0890840A3 (en) 2000-05-17
DE69033082T2 (de) 1999-09-30
US5576189A (en) 1996-11-19
WO1991008478A3 (en) 1991-11-28
DK0682257T3 (da) 1999-11-08
ATE133790T1 (de) 1996-02-15
DE502928T1 (de) 1994-08-18
JPH09113510A (ja) 1997-05-02
JP3299941B2 (ja) 2002-07-08
NO922149D0 (no) 1992-05-29

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