DK0667920T3 - Fremgangsmåder til påvisning af prostatacancermetastase - Google Patents

Fremgangsmåder til påvisning af prostatacancermetastase

Info

Publication number
DK0667920T3
DK0667920T3 DK93925095T DK93925095T DK0667920T3 DK 0667920 T3 DK0667920 T3 DK 0667920T3 DK 93925095 T DK93925095 T DK 93925095T DK 93925095 T DK93925095 T DK 93925095T DK 0667920 T3 DK0667920 T3 DK 0667920T3
Authority
DK
Denmark
Prior art keywords
prostate cancer
methods
cancer metastasis
detecting prostate
rna
Prior art date
Application number
DK93925095T
Other languages
Danish (da)
English (en)
Inventor
Carlo Croce
Leonard Gomella
Grant S Mulholland
Jose G Moreno
Rainer Fischer
Original Assignee
Univ Jefferson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Jefferson filed Critical Univ Jefferson
Application granted granted Critical
Publication of DK0667920T3 publication Critical patent/DK0667920T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK93925095T 1992-10-29 1993-10-27 Fremgangsmåder til påvisning af prostatacancermetastase DK0667920T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97332292A 1992-10-29 1992-10-29
PCT/US1993/010331 WO1994010343A1 (fr) 1992-10-29 1993-10-27 Procedes de detection de micrometastase du cancer de la prostate

Publications (1)

Publication Number Publication Date
DK0667920T3 true DK0667920T3 (da) 2003-04-14

Family

ID=25520753

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93925095T DK0667920T3 (da) 1992-10-29 1993-10-27 Fremgangsmåder til påvisning af prostatacancermetastase

Country Status (10)

Country Link
US (2) US5506106A (fr)
EP (1) EP0667920B1 (fr)
JP (1) JPH08502889A (fr)
AT (1) ATE231187T1 (fr)
CA (1) CA2148350A1 (fr)
DE (1) DE69332642T2 (fr)
DK (1) DK0667920T3 (fr)
ES (1) ES2191018T3 (fr)
PT (1) PT667920E (fr)
WO (1) WO1994010343A1 (fr)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2148350A1 (fr) * 1992-10-29 1994-05-11 Carlo Croce Methodes de detection des micrometastases du cancer de la prostate
US5674682A (en) * 1992-10-29 1997-10-07 Thomas Jefferson University Nucleic acid primers for detecting micrometastasis of prostate cancer
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
EP0760006A1 (fr) * 1994-04-15 1997-03-05 The Trustees Of Columbia University In The City Of New York Procede de d'evaluation au niveau moleculaire des stades d'evolution du cancer de la prostate
EP0804593A1 (fr) * 1994-05-10 1997-11-05 Mayo Foundation For Medical Education And Research Polypeptide hk2 recombine
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
AU4897896A (en) * 1995-01-04 1996-07-24 Trustees Of Boston University Primers for the pcr amplification of metastatic sequences
AUPN274295A0 (en) * 1995-05-02 1995-05-25 Garvan Institute Of Medical Research GDU, a novel signalling protein
US6218529B1 (en) 1995-07-31 2001-04-17 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
US6329179B1 (en) * 1996-03-26 2001-12-11 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US7785842B2 (en) * 1996-03-26 2010-08-31 Oncomedx, Inc. Comparative analysis of extracellular RNA species
US8043835B1 (en) 1996-03-26 2011-10-25 Oncomedx, Inc. Methods for detecting and monitoring cancer using extracellular RNA
US6759217B2 (en) * 1996-03-26 2004-07-06 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US5861248A (en) * 1996-03-29 1999-01-19 Urocor, Inc. Biomarkers for detection of prostate cancer
EP0904397A4 (fr) * 1996-04-16 2003-01-29 Smithkline Beecham Corp Procede de detection de l'antigene specifique de la prostate utilise pour surveiller et diagnostiquer le cancer de la prostate
US5925519A (en) * 1996-06-03 1999-07-20 The Regents Of The University Of California Genetic alterations associated with prostate cancer
CA2744096C (fr) * 1996-07-31 2013-07-30 Laboratory Corporation Of America Holdings Biomarqueurs et cibles de diagnostic, de pronostic et de traitement du cancer de la prostate
CN1238013A (zh) * 1996-11-14 1999-12-08 梅奥医学教育及研究基金会 转移性前列腺癌的检测方法
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
CA2273847C (fr) * 1996-12-06 2013-08-13 Urocor, Inc. Diagnostic d'etat pathologique a l'aide de profils d'arn messager
AU6551398A (en) * 1997-03-11 1998-09-29 Anna C. Ferrari Method of detecting prostate cancer metastasis
US20070009934A1 (en) * 1997-03-14 2007-01-11 Kopreski Michael S Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US8440396B2 (en) * 1997-03-14 2013-05-14 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US6190857B1 (en) * 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
US7332270B1 (en) 1997-03-24 2008-02-19 Urocor, Inc. Diagnosis of disease state using mRNA profiles in peripheral leukocytes
NO972006D0 (no) * 1997-04-30 1997-04-30 Forskningsparken I Aas As Ny metode for diagnose av sykdommer
US7659073B2 (en) 1997-04-30 2010-02-09 Hybritech Incorporated Forms of prostate specific antigens and methods for their detection
US7288636B2 (en) 1997-04-30 2007-10-30 Hybritech Incorporated Forms of prostate specific antigens and methods for their detection
WO1998049323A1 (fr) * 1997-04-30 1998-11-05 Hybritech Incorporated Formes d'antigene a specificite prostatique (asp) et leurs procedes de detection
WO1998059073A1 (fr) 1997-06-20 1998-12-30 Mayo Foundation For Medical Education And Research Procede de detection du cancer du sein
DE19736691A1 (de) * 1997-08-22 1999-02-25 Michael Prof Dr Med Giesing Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen
CA2303404A1 (fr) * 1997-09-11 1999-03-18 Abbott Laboratories Reactifs et methodes servant a detecter les maladies de la prostate
US6300088B1 (en) 1997-11-24 2001-10-09 Duke University Method of detecting prostate specific antigen
US5972615A (en) * 1998-01-21 1999-10-26 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate disease
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
CA2330628A1 (fr) 1998-05-01 1999-11-11 Queen's University At Kingston Procede de diagnostic sur l'etat du systeme vasculaire
EP1082460A4 (fr) * 1998-05-21 2003-02-12 Diadexus Inc Nouveau procede de diagnostic, de surveillance et de stadification du cancer de la prostate
US6861215B1 (en) 1998-05-21 2005-03-01 Diadexus, Inc. Method of diagnosing, monitoring, and staging prostate cancer
US7226731B1 (en) 1998-07-24 2007-06-05 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services PB 39, a gene dysregulated in prostate cancer, and uses thereof
AU5128799A (en) * 1998-07-24 2000-02-14 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Pb 39, a gene dysregulated in prostate cancer, and uses thereof
FR2782730B1 (fr) * 1998-08-25 2002-05-17 Biocom Sa Procede de separation cellulaire pour l'isolation de cellules pathogeniques, notamment cancereuses rares, equipement et reactif pour la mise en oeuvre du procede et application du procede
US8163524B2 (en) * 1998-09-22 2012-04-24 Oncomedx, Inc. Comparative analysis of extracellular RNA species
US20090233276A1 (en) * 1998-09-22 2009-09-17 Oncomedx, Inc. Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions
US20060204989A1 (en) * 1998-09-22 2006-09-14 Kopreski Michael S Comparative analysis of extracellular RNA species
CA2360073C (fr) * 1999-01-28 2011-01-18 Gen-Probe Incorporated Sondes et amorces pour la detection d'antigene prostatique specifique (psa) dans un echantillon biologique
US6156515A (en) 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
US6875854B1 (en) 1999-11-18 2005-04-05 The Brigham And Women's Hospital, Inc. Compositions and methods for the improved diagnosis and treatment of germ cell tumors
WO2003009806A2 (fr) * 2001-07-25 2003-02-06 Oncomedx Inc. Methodes d'evaluation d'affections pathologiques utilisant un arn extracellulaire
US20030104454A1 (en) * 2001-11-05 2003-06-05 Kopreski Michael S. Method for detection of DNA methyltransferase RNA in plasma and serum
US20100159464A1 (en) * 2001-11-05 2010-06-24 Oncomedx, Inc. Method for Detection of DNA Methyltransferase RNA in Plasma and Serum
CA2432365A1 (fr) * 2003-06-30 2004-12-30 Jack A. Schalken Methode specifique de detection du cancer de la prostate fondee sur le gene pca3 et trousses connexes
CA2617581A1 (fr) * 2005-08-01 2007-02-08 The Ohio State University Research Foundation Procedes a base de micro-arn pour le diagnostic du cancer du sein
EP1937280B1 (fr) * 2005-09-12 2014-08-27 The Ohio State University Research Foundation Compositions pour le traitement de cancers associes au gene bcl2
WO2007044413A2 (fr) * 2005-10-05 2007-04-19 The Ohio State University Research Foundation Gene wwox, vecteurs renfermant celui-ci et utilisations de ceux-ci dans le traitement de cancer
EP2487258B1 (fr) 2006-01-05 2014-10-01 The Ohio State University Research Foundation Procédés à base de micro ARN pour le diagnostic de cancer du côlon, du pancréas et de l'estomac
CA2635616A1 (fr) 2006-01-05 2007-07-19 Carlo M. Croce Anomalies dans l'expression des micro-arn dans des tumeurs endocrines pancreatiques et des tumeurs a cellules acineuses
US7943318B2 (en) 2006-01-05 2011-05-17 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer
CN101448958A (zh) 2006-03-20 2009-06-03 俄亥俄州立大学研究基金会 人巨核细胞生成期间的微小rna指纹
ES2562607T3 (es) * 2006-07-13 2016-03-07 The Ohio State University Research Foundation MIR-21 para el diagnóstico de adenocarcinoma de colon con mal pronóstico de supervivencia
ES2374446T3 (es) * 2006-09-19 2012-02-16 The Ohio State University Research Foundation Expresión de tcl1 en la leucemia linfocítica crónica (llc) regulada por mir-29 y mir-181.
US8252538B2 (en) 2006-11-01 2012-08-28 The Ohio State University MicroRNA expression signature for predicting survival and metastases in hepatocellular carcinoma
CA2674895A1 (fr) * 2007-01-31 2008-08-07 The Ohio State University Research Foundation Methodes et compositions a base de micro-arn pour le diagnostic, le pronostic et le traitement de la leucemie aigue myeloide (lam)
WO2008136971A1 (fr) * 2007-04-30 2008-11-13 The Ohio State University Research Foundation Procédé de différenciation entre le cancer du pancréas et une fonction pancréatique normale et/ou la pancréatite chronique
CN105950706A (zh) * 2007-06-08 2016-09-21 由卫生与公众服务部代表的美利坚合众国政府 确定肝细胞癌亚型和检测肝癌干细胞的方法
CA2690749A1 (fr) 2007-06-15 2008-12-24 The Ohio State University Research Foundation Proteines de fusion all-1 oncogenes pour cibler le traitement de micro-arn regule par drosha
CN101809169B (zh) * 2007-07-31 2013-07-17 俄亥俄州立大学研究基金会 通过靶向dnmt3a和dnmt3b恢复甲基化的方法
ES2570359T3 (es) 2007-08-03 2016-05-18 Univ Ohio State Res Found Regiones ultraconservadas que codifican ARNnc
DE102007037008B4 (de) * 2007-08-06 2015-09-10 Siemens Aktiengesellschaft Diagnosesubstanz zur Anwendung in einem Verfahren zur Bestimmung der Aggressivität eines Prostatatumors
EP2183593B1 (fr) * 2007-08-22 2016-01-13 The Ohio State University Research Foundation Procédés et compositions pour induire une dérégulation de la phosphorylation de epha7 et de erk dans des cas de leucémies humaines aigües
JP5401460B2 (ja) * 2007-09-06 2014-01-29 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション ヒト卵巣癌中のマイクロｒｎａシグネチャー
US20090136942A1 (en) * 2007-09-18 2009-05-28 Oncomedx, Inc. Analysis of Extracellular RNA
JP5723156B2 (ja) * 2007-10-11 2015-05-27 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイションＴｈｅ Ｏｈｉｏ Ｓｔａｔｅ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ 食道腺癌の診断及び治療のための方法及び組成物
US8911998B2 (en) 2007-10-26 2014-12-16 The Ohio State University Methods for identifying fragile histidine triad (FHIT) interaction and uses thereof
AU2008329755A1 (en) * 2007-11-30 2009-06-04 The Ohio State University Research Foundation MicroRNA expression profiling and targeting in peripheral blood in lung cancer
CN104031984A (zh) * 2008-02-28 2014-09-10 俄亥俄州立大学研究基金会 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物
AU2009219193A1 (en) * 2008-02-28 2009-09-03 The Ohio State University Research Foundation MicroRNA signatures associated with human chronic lymphocytic leukemia (CCL) and uses thereof
AU2009257410B2 (en) 2008-06-11 2014-03-06 Fudan University Use of miR-26 family as a predictive marker of hepatocellular carcinoma and responsiveness to therapy
AU2010321555B2 (en) 2009-11-23 2015-10-15 The Ohio State University Materials and methods useful for affecting tumor cell growth, migration and invasion
US8946187B2 (en) 2010-11-12 2015-02-03 The Ohio State University Materials and methods related to microRNA-21, mismatch repair, and colorectal cancer
CA2817982C (fr) 2010-11-15 2020-06-30 The Regents Of The University Of Michigan Systemes mucoadhesifs a liberation controlee
EP2683387A4 (fr) 2011-03-07 2014-09-03 Univ Ohio State Activité mutatrice induite par l'inflammation des liaisons au microarn-155 (mir-155) et le cancer
US9249468B2 (en) 2011-10-14 2016-02-02 The Ohio State University Methods and materials related to ovarian cancer
EP2790735A4 (fr) 2011-12-13 2015-12-09 Ohio State Innovation Foundation Procédés et compositions se rapportant à mir-21 et mir-29a, à l'inhibition d'exosome, et à la métastase cancéreuse
AU2013209477B2 (en) 2012-01-20 2016-12-08 The Ohio State University Breast cancer biomarker signatures for invasiveness and prognosis
CN111518170A (zh) * 2020-05-09 2020-08-11 新乡医学院 基于fret的psa荧光探针、制备方法及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446122A (en) * 1979-12-28 1984-05-01 Research Corporation Purified human prostate antigen
US5176995A (en) * 1985-03-28 1993-01-05 Hoffmann-La Roche Inc. Detection of viruses by amplification and hybridization
US5153118A (en) * 1985-12-17 1992-10-06 Eastern Virginia Medical Authority Monoclonal antibodies having binding specificity to human prostate tumor-associated antigens and methods for employing the same
US4803169A (en) * 1986-02-05 1989-02-07 Cetus Corporation Assay for human breast cancer
US5085983A (en) * 1988-08-19 1992-02-04 City Of Hope Detection of human tumor progression and drug resistance
AU662906B2 (en) * 1991-06-26 1995-09-21 F. Hoffmann-La Roche Ag Methods for detection of carcinoma metastases by nucleic acid amplification
CA2148350A1 (fr) * 1992-10-29 1994-05-11 Carlo Croce Methodes de detection des micrometastases du cancer de la prostate

Also Published As

Publication number Publication date
CA2148350A1 (fr) 1994-05-11
JPH08502889A (ja) 1996-04-02
PT667920E (pt) 2003-06-30
WO1994010343A1 (fr) 1994-05-11
US5688649A (en) 1997-11-18
EP0667920A1 (fr) 1995-08-23
ATE231187T1 (de) 2003-02-15
ES2191018T3 (es) 2003-09-01
DE69332642D1 (de) 2003-02-20
DE69332642T2 (de) 2003-10-02
US5506106A (en) 1996-04-09
EP0667920A4 (fr) 1998-12-16
EP0667920B1 (fr) 2003-01-15

Similar Documents

Publication Publication Date Title
DK0667920T3 (da) Fremgangsmåder til påvisning af prostatacancermetastase
ATE121794T1 (de) Verfahren zum nachweis des karzinogenen menschlichen papillomavirus.
FR2694754B1 (fr) Fragments d'ADN de mycobactéries, amorces d'amplification, sondes d'hybridation, réactifs et procédé de détection de détection de mycobactéries.
CA2072314A1 (fr) Methodes de detection des metastases par l'amplification de l'acide nucleique
ATE360808T1 (de) Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren
NO975508L (no) DNA-sekvens og kodet bryst- spesifikt brystkreftprotein
DK1038022T3 (da) Evaluering af humane papillomavirus-tilknyttede sygdomme
ATE133715T1 (de) Verfahren zum nachweis von gesplei ter mrna
NO964187D0 (no) Fremgangsmåte for fremstilling av mykobakterier
FR2810406B1 (fr) Nouveaux cryptates de terre rare peu sensibles a l'extinction de fluorescence
ES2170145T3 (es) Sustancias y procedimientos de deteccion de micobacterium tuberculosis.
FR2670797B1 (fr)
PT968421E (pt) Diagnostico precoce do cancro gastrico
DE69630142D1 (de) Verfahren zur identifizierung metastatischer sequenzen
WO2002006537A3 (fr) Methodes permettant d'identifier des facteurs de protection renaux
DK0461496T3 (da) Fremgangsmåde til kvantitativ bestemmelse af DNA-sekvenser
ATE184055T1 (de) Verfahren zum sensitiven nachweis von reverser transcriptase
FR2694768B1 (fr) Séquences d'oligonucléotides pour la détection spécifique de mollicutes par amplication de gènes conservés.
DE69214843D1 (de) Verfahren zum nachweis von beschädigungen des magenepithels
GB9510954D0 (en) Detection of DNA damage
FR2678285B1 (fr)
ATE251223T1 (de) Immuno-magnetische zelltrennung zur erkennung von krebsmetastasenbildung-assozierten genen
ATE219149T1 (de) Verfahren zur bestimmung von crohn's krankheit und colitis ulcerosa
DE69635025D1 (de) Neues verfahren zum nachweis von cryptosporidium
WO1999058712A3 (fr) Detection de genes