ATE360808T1 - Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren - Google Patents

Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren

Info

Publication number
ATE360808T1
ATE360808T1 AT96923760T AT96923760T ATE360808T1 AT E360808 T1 ATE360808 T1 AT E360808T1 AT 96923760 T AT96923760 T AT 96923760T AT 96923760 T AT96923760 T AT 96923760T AT E360808 T1 ATE360808 T1 AT E360808T1
Authority
AT
Austria
Prior art keywords
detection
extraction
amplification
nucleic acid
nucleic acids
Prior art date
Application number
AT96923760T
Other languages
English (en)
Inventor
John C Gerdes
Lynn D Jankovsky
Diane L Kozwich
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of ATE360808T1 publication Critical patent/ATE360808T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT96923760T 1995-07-13 1996-07-12 Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren ATE360808T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88595P 1995-07-13 1995-07-13

Publications (1)

Publication Number Publication Date
ATE360808T1 true ATE360808T1 (de) 2007-05-15

Family

ID=21693436

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96923760T ATE360808T1 (de) 1995-07-13 1996-07-12 Unabhängiges gerät zur extraktion, amplifikation und nachweis von nukleinsäuren

Country Status (8)

Country Link
US (1) US5955351A (de)
EP (1) EP0838025B1 (de)
JP (1) JPH11509100A (de)
AT (1) ATE360808T1 (de)
AU (1) AU718183B2 (de)
CA (1) CA2226717A1 (de)
DE (1) DE69637047T2 (de)
WO (1) WO1997003348A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6986985B1 (en) * 1994-01-13 2006-01-17 Enzo Life Sciences, Inc. Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct
US20050123926A1 (en) * 1994-01-13 2005-06-09 Enzo Diagnostics, Inc., In vitro process for producing multiple nucleic acid copies
US20110097791A1 (en) * 1999-04-16 2011-04-28 Engelhardt Dean L Novel process, construct and conjugate for producing multiple nucleic acid copies
US6153425A (en) * 1995-07-13 2000-11-28 Xtrana, Inc. Self-contained device integrating nucleic acid extraction, amplification and detection
US5989499A (en) * 1997-05-02 1999-11-23 Biomerieux, Inc. Dual chamber disposable reaction vessel for amplification reactions
US6429007B1 (en) 1997-05-02 2002-08-06 BIOMéRIEUX, INC. Nucleic acid amplification reaction station for disposable test devices
US6410275B1 (en) 1997-05-02 2002-06-25 Biomerieux, Inc. Disposable test devices for performing nucleic acid amplification reactions
ES2249818T3 (es) * 1997-06-09 2006-04-01 F. Hoffmann-La Roche Ag Dispositivo desechable despues de su uso en un proceso.
WO1999033559A1 (en) 1997-12-24 1999-07-08 Cepheid Integrated fluid manipulation cartridge
DE69940647D1 (de) 1998-05-01 2009-05-07 Gen Probe Inc Automatische diagnostische Analysevorrichtung
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
US6413780B1 (en) 1998-10-14 2002-07-02 Abbott Laboratories Structure and method for performing a determination of an item of interest in a sample
JP2002528093A (ja) * 1998-10-23 2002-09-03 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 表面における核酸の単離及び精製のための方法並びに手段
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US6391541B1 (en) * 1999-05-28 2002-05-21 Kurt E. Petersen Apparatus for analyzing a fluid sample
US9073053B2 (en) * 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US6159727A (en) * 1999-06-04 2000-12-12 Clontech Laboratories, Inc. Hybridization chamber
WO2000077253A1 (en) * 1999-06-16 2000-12-21 Hitachi, Ltd. Apparatus and method for gene examination
US6664104B2 (en) 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
DE19963032A1 (de) 1999-12-24 2001-06-28 Roche Diagnostics Gmbh System zur Bearbeitung von Proben in einer Mehrkammeranordnung
DE10006214A1 (de) 2000-02-11 2001-08-16 Roche Diagnostics Gmbh System zur einfachen Nukleinsäureanalytik
US20080260593A1 (en) * 2000-03-22 2008-10-23 Dewalch Norman Binz Method and apparatus for processing substances in a single container
ATE487539T1 (de) * 2000-03-22 2010-11-15 Dewalch Technologies Inc Verfahren und gerät zur verarbeitung von substanzen in einem einzigen behälter
US6869532B2 (en) * 2001-06-04 2005-03-22 Cuno Incorporated Nucleic acid binding matrix
US20030098271A1 (en) * 2001-11-26 2003-05-29 Ralph Somack Capsule and tray systems for combined sample collection, archiving, purification, and PCR
US20040014097A1 (en) * 2002-05-06 2004-01-22 Mcglennen Ronald C. Genetic test apparatus and method
EP1525055A1 (de) * 2002-07-12 2005-04-27 British Biocell International Limited Vorrichtung zur Nukleinsäuresequenzanalyse mittels Querflussaufbau und Verfahrenzur Verwendung desselben
US20060278242A1 (en) * 2005-03-23 2006-12-14 Mcglennen Ronald C Apparatus and methods for medical testing
US8594948B2 (en) * 2002-09-18 2013-11-26 Ronald C. McGlennen Apparatus and methods for medical testing
US7217542B2 (en) * 2002-10-31 2007-05-15 Hewlett-Packard Development Company, L.P. Microfluidic system for analyzing nucleic acids
US7597936B2 (en) * 2002-11-26 2009-10-06 University Of Utah Research Foundation Method of producing a pigmented composite microporous material
WO2004048936A2 (en) * 2002-11-26 2004-06-10 University Of Utah Research Foundation Microporous materials, methods, and articles for localizing and quantifying analytes
DE102004021822B3 (de) * 2004-04-30 2005-11-17 Siemens Ag Verfahren und Anordnung zur DNA-Amplifikation mittels PCR unter Einsatz von Trockenreagenzien
DE102004021780B4 (de) * 2004-04-30 2008-10-02 Siemens Ag Verfahren und Anordnung zur DNA-Isolierung mit Trockenreagenzien
US20060264714A1 (en) * 2005-03-23 2006-11-23 Mcglennen Ronald C Apparatus and methods for medical testing
GB0604973D0 (en) * 2006-03-11 2006-04-19 Central Science Lab Csl Of San Purification method and kit
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
WO2008012550A2 (en) * 2006-07-28 2008-01-31 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
WO2008014485A2 (en) 2006-07-28 2008-01-31 California Institute Of Technology Multiplex q-pcr arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
CN1888902B (zh) * 2006-08-11 2011-05-18 杭州优思达生物技术有限公司 全封闭式靶核酸扩增物快速检测装置
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
US7492312B2 (en) * 2006-11-14 2009-02-17 Fam Adly T Multiplicative mismatched filters for optimum range sidelobe suppression in barker code reception
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
CN103157400B (zh) 2007-06-21 2014-12-24 简·探针公司 用于将容器暴露于多个热区的仪器和方法
DE102007029772B4 (de) * 2007-06-22 2011-12-08 Aj Innuscreen Gmbh Verfahren und Schnelltest zum Nachweis spezifischer Nukleinsäuresequenzen
IL184183A0 (en) * 2007-06-25 2007-10-31 Benjamin Alspector Bi directional transfer of an aliquot of fluid between compartments
US8415141B2 (en) * 2007-08-17 2013-04-09 Qimin You Enclosed unit for rapid detection of a target nucleic acid amplification product
WO2009024773A1 (en) 2007-08-17 2009-02-26 Diagnostics For The Real World, Ltd Device, system and method for processing a sample
EP2207893B1 (de) 2007-10-19 2011-12-28 Becton, Dickinson and Company Verfahren zum nachweis von beta-lactamase
US9409166B2 (en) * 2007-12-10 2016-08-09 The Trustees Of The University Of Pennsylvania Integrated PCR reactor for cell lysis, nucleic acid isolation and purification, and nucleic acid amplication related applications
WO2009106838A1 (en) * 2008-02-29 2009-09-03 Isis Innovation Limited Diagnostic methods
US9817001B2 (en) 2008-05-27 2017-11-14 Boston Heart Diagnostics Corporation Methods for determining LDL cholesterol treatment
US8470541B1 (en) * 2008-09-27 2013-06-25 Boston Heart Diagnostics Corporation Methods for separation and immuno-detection of biomolecules, and apparatus related thereto
WO2010047778A1 (en) * 2008-10-20 2010-04-29 Becton Dickinson And Company Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets
WO2010075025A2 (en) * 2008-12-16 2010-07-01 Shell Oil Company Device for evaluating a heat exchange fluid
US9121054B2 (en) * 2009-12-08 2015-09-01 Biohelix Corporation Detection of nucleic acid amplification products in the presence of an internal control sequence on an immunochromatographic strip
KR20130029128A (ko) 2010-07-23 2013-03-21 베크만 컬터, 인코포레이티드 실시간 pcr용 용기
JP5051557B2 (ja) * 2010-11-09 2012-10-17 株式会社ジェイ・エム・エス 分離容器および分離方法
CA2851838A1 (en) 2011-10-13 2013-04-18 Boston Heart Diagnostics Corporation Compositions and methods for treating and preventing coronary heart disease
WO2013070755A2 (en) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Centrifuge system and workflow
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
EP3373015A1 (de) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotierungssystem und arbeitsablauf
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
US9910054B2 (en) 2011-11-07 2018-03-06 Beckman Coulter, Inc. System and method for processing samples
CN104040352B (zh) 2011-11-07 2016-09-07 贝克曼考尔特公司 机械臂
US10428375B2 (en) 2012-02-03 2019-10-01 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
EP2864503B1 (de) * 2012-06-26 2019-10-09 Axxin Pty Ltd Nukleinsäureamplifikations- und -nachweiskit
JP6166938B2 (ja) * 2013-04-18 2017-07-19 ローム株式会社 マイクロチップ
US9828624B2 (en) 2013-07-24 2017-11-28 Boston Heart Diagnostics Corporation Driving patient compliance with therapy
WO2015187849A2 (en) 2014-06-04 2015-12-10 Lucigen Corporation Sample collection and analysis devices
US10472620B2 (en) 2014-07-01 2019-11-12 General Electric Company Method, substrate and device for separating nucleic acids
US10870845B2 (en) 2014-07-01 2020-12-22 Global Life Sciences Solutions Operations UK Ltd Methods for capturing nucleic acids
US9593368B2 (en) 2014-07-01 2017-03-14 General Electric Company Methods for amplifying nucleic acids on substrates
AU2015346009B2 (en) 2014-11-14 2020-07-23 Axxin Pty Ltd Biological sample collection and storage assembly
CA2968221A1 (en) 2014-11-17 2016-05-26 Boston Heart Diagnostic Corporation Cardiovascular disease risk assessment
WO2017011862A1 (en) 2015-07-17 2017-01-26 Axxin Pty Ltd Diagnostic test assembly, apparatus, method
EP3400284A4 (de) * 2016-01-08 2019-10-23 Advanced Theranostics Inc. Vollintegrierte, eigenständige versorgungsortvorrichtung zum nachweis von zielnukleinsäuren
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
CN110621770B (zh) 2017-04-19 2024-04-09 耶马都惠须龙株式会社 Pcr用容器、装试剂的pcr用容器及试剂盒
WO2019060950A1 (en) 2017-09-27 2019-04-04 Axxin Pty Ltd SYSTEM AND METHOD FOR DIAGNOSTIC TESTING
CA3120216A1 (en) * 2018-11-19 2020-05-28 Biocartis Nv Enhanced detection of low-copy-number nucleic acids in an integrated workflow
EP3937780A4 (de) 2019-03-14 2022-12-07 InSilixa, Inc. Verfahren und systeme zur zeitgesteuerten fluoreszenzbasierten detektion
JP2024510383A (ja) * 2020-10-26 2024-03-07 ティエリー ナバロ Ｄｎａまたはｒｎａ増幅装置とその手法
CN113249214B (zh) * 2021-07-05 2022-05-10 广州和实生物技术有限公司 一种可家庭自测的核酸检测装置、其使用方法及用途

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3715189A (en) * 1970-06-15 1973-02-06 Secretary Of The Treasury Qualitative analysis device
US4473530A (en) * 1980-09-24 1984-09-25 Villa Real Antony Euclid C Compact sanitary urinalysis unit
CA1219824A (en) * 1981-04-17 1987-03-31 David C. Ward Modified nucleotides and methods of preparing and using same
US4458020A (en) * 1982-11-15 1984-07-03 Quidel Integrated single tube plunger immunoassay system having plural reagent chambers
US4687732A (en) * 1983-06-10 1987-08-18 Yale University Visualization polymers and their application to diagnostic medicine
DE3431536A1 (de) * 1984-08-28 1986-03-13 Boehringer Mannheim Gmbh, 6800 Mannheim Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5310650A (en) * 1986-09-29 1994-05-10 Abbott Laboratoires Method and device for improved reaction kinetics in nucleic acid hybridizations
FR2612297B1 (fr) * 1987-03-10 1990-10-05 Pasteur Diagnostics Dispositif de laboratoire pour analyse necessitant la mise en contact transitoire d'une phase solide et d'une phase liquide
GB8728639D0 (en) * 1987-12-08 1988-01-13 Scient Generics Ltd Device for analytical determinations
CA1323293C (en) * 1987-12-11 1993-10-19 Keith C. Backman Assay using template-dependent nucleic acid probe reorganization
DE3813278A1 (de) * 1988-01-12 1989-07-20 Boehringer Mannheim Gmbh Verfahren zum nachweis von nukleinsaeuren
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
CA2031659A1 (en) * 1990-01-26 1991-07-27 John B. Findlay Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
SE465086B (sv) * 1990-05-16 1991-07-22 Mats Malmquist Reagenskapillaerer, reaktionskaerl, beredningssaett och anvaendning daerav
US5114858A (en) * 1990-06-26 1992-05-19 E. I. Du Pont De Nemours And Company Cellular component extraction process in a disposable filtration vessel
JPH04187077A (ja) * 1990-11-22 1992-07-03 Shimadzu Corp 核酸の抽出精製装置
US5455166A (en) * 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5230864A (en) * 1991-04-10 1993-07-27 Eastman Kodak Company Gravity assisted collection device
US5387510A (en) * 1991-10-02 1995-02-07 Eastman Kodak Company Detection of amplified nucleic acid using secondary capture oligonucleotides and test kit
IL102486A (en) * 1991-10-04 1997-11-20 Orgenics Ltd Method and apparatus for detection of nucleic acid sequences with a nucleic acid probe
DE4143639C2 (de) * 1991-12-02 2002-10-24 Qiagen Gmbh Verfahren zur Isolierung und Reinigung von Nukleinsäuren
US5244635A (en) * 1992-06-19 1993-09-14 Cirrus Diagnostics, Inc. Centrifuge vessel with coaxial waste chamber having cap to prevent waste fluid transfer from the chamber into the vessel
EP0609431B1 (de) * 1992-08-24 1997-10-08 Dade MicroScan Inc. Abdichtbarer behälter zum konservieren und behandeln analytischer proben
DE4321904B4 (de) * 1993-07-01 2013-05-16 Qiagen Gmbh Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen
US5415839A (en) * 1993-10-21 1995-05-16 Abbott Laboratories Apparatus and method for amplifying and detecting target nucleic acids
JP3034954B2 (ja) * 1993-10-22 2000-04-17 アボツト・ラボラトリーズ 汚染を最小限にするための反応チューブおよび使用方法
US5725831A (en) * 1994-03-14 1998-03-10 Becton Dickinson And Company Nucleic acid amplification apparatus
DE4412286A1 (de) * 1994-04-09 1995-10-12 Boehringer Mannheim Gmbh System zur kontaminationsfreien Bearbeitung von Reaktionsabläufen
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
US5639428A (en) * 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
US5955351A (en) 1999-09-21
WO1997003348A1 (en) 1997-01-30
AU6458096A (en) 1997-02-10
CA2226717A1 (en) 1997-01-30
EP0838025B1 (de) 2007-04-25
DE69637047D1 (de) 2007-06-06
EP0838025A1 (de) 1998-04-29
EP0838025A4 (de) 1999-10-06
JPH11509100A (ja) 1999-08-17
DE69637047T2 (de) 2007-12-27
AU718183B2 (en) 2000-04-06

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