DE60040335D1 - Derivatisierte nukleinsäuren und deren verwendung - Google Patents

Derivatisierte nukleinsäuren und deren verwendung

Info

Publication number
DE60040335D1
DE60040335D1 DE60040335T DE60040335T DE60040335D1 DE 60040335 D1 DE60040335 D1 DE 60040335D1 DE 60040335 T DE60040335 T DE 60040335T DE 60040335 T DE60040335 T DE 60040335T DE 60040335 D1 DE60040335 D1 DE 60040335D1
Authority
DE
Germany
Prior art keywords
derivated
nucleic acids
sample
nucleic acid
invention features
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60040335T
Other languages
English (en)
Inventor
David F Englert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Packard Bioscience Co
Original Assignee
Packard Bioscience Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Packard Bioscience Co filed Critical Packard Bioscience Co
Application granted granted Critical
Publication of DE60040335D1 publication Critical patent/DE60040335D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60040335T 1999-07-14 2000-07-14 Derivatisierte nukleinsäuren und deren verwendung Expired - Lifetime DE60040335D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14380499P 1999-07-14 1999-07-14
PCT/US2000/019176 WO2001006012A1 (en) 1999-07-14 2000-07-14 Derivative nucleic acids and uses thereof

Publications (1)

Publication Number Publication Date
DE60040335D1 true DE60040335D1 (de) 2008-11-06

Family

ID=22505724

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60040335T Expired - Lifetime DE60040335D1 (de) 1999-07-14 2000-07-14 Derivatisierte nukleinsäuren und deren verwendung

Country Status (6)

Country Link
EP (1) EP1194592B1 (de)
AT (1) ATE409236T1 (de)
AU (1) AU6345700A (de)
CA (1) CA2379132C (de)
DE (1) DE60040335D1 (de)
WO (1) WO2001006012A1 (de)

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US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
CA2450139A1 (en) * 2001-06-11 2002-12-19 Illumina, Inc Multiplexed detection methods
US20110151438A9 (en) 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
CA2467577A1 (en) 2001-11-19 2003-05-30 Parallele Bioscience, Inc. Multiplex pcr
EP1319718A1 (de) * 2001-12-14 2003-06-18 Keygene N.V. Hochdurchsatzanalyse und Detektion von mehreren Zielsequenzen
US20030235827A1 (en) * 2002-06-25 2003-12-25 Orchid Biosciences, Inc. Methods and compositions for monitoring primer extension and polymorphism detection reactions
US7595883B1 (en) 2002-09-16 2009-09-29 The Board Of Trustees Of The Leland Stanford Junior University Biological analysis arrangement and approach therefor
CN1318606C (zh) * 2002-09-19 2007-05-30 阿普里拉股份有限公司 检测靶序列的方法和组合物
AU2003275138A1 (en) * 2002-09-19 2004-04-08 Applied Biosystems, Llc. Methods and compositions for detecting targets
AU2003202671A1 (en) * 2003-01-21 2004-08-13 Guoliang Fu Quantitative multiplex detection of nucleic acids
WO2004065628A1 (en) * 2003-01-21 2004-08-05 Guoliang Fu Quantitative multiplex detection of nucleic acids
WO2005026389A2 (en) * 2003-08-29 2005-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna
ES2539784T3 (es) * 2003-09-02 2015-07-06 Keygene N.V. Procedimientos basados en OLA para la detección de secuencias de ácidos nucleicos objetivo
US7531306B2 (en) * 2003-11-12 2009-05-12 Geneohm Sciences, Inc. Nucleic acid hybridization methods
WO2006005080A2 (en) * 2004-06-30 2006-01-12 Applera Corporation Method for detection of a nucleic acid sequence
WO2006005081A2 (en) * 2004-06-30 2006-01-12 Applera Corporation Compositions and methods for identifying nucleotides in polynucleotide sequences
WO2010057525A1 (en) * 2008-11-19 2010-05-27 Fondazione Parco Tecnologico Padano Oligonucleotide primers for nucleotide indexing of polymorphic pcr products and methods for their use
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
CN105779604A (zh) * 2011-02-10 2016-07-20 三菱丽阳株式会社 核酸的检测方法
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
EP3225698B1 (de) 2011-09-06 2019-07-31 Gen-Probe Incorporated Geschlossene nukleinsäurestrukturen
DE102011055247A1 (de) 2011-11-10 2013-05-16 Albert-Ludwigs-Universität Freiburg Multianalyt-Reportersystem
CN105849275B (zh) 2013-06-25 2020-03-17 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
GB2536446B (en) * 2015-03-17 2020-06-03 Salisbury Nhs Found Trust PCR method
EP3530752B1 (de) 2015-04-10 2021-03-24 Spatial Transcriptomics AB Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben
WO2018186930A1 (en) * 2017-04-06 2018-10-11 MyOmicsDx, Inc Method and kit for constructing nucleic acid library
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
EP3894585A2 (de) 2018-12-10 2021-10-20 10X Genomics, Inc. Erzeugung von erfassungssonden zur räumlichen analyse
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
EP3976820A1 (de) 2019-05-30 2022-04-06 10X Genomics, Inc. Verfahren zum nachweis der räumlichen heterogenität einer biologischen probe
EP4025711A2 (de) 2019-11-08 2022-07-13 10X Genomics, Inc. Erhöhung der spezifität einer analytbindung
SG11202106899SA (en) 2019-12-23 2021-09-29 10X Genomics Inc Methods for spatial analysis using rna-templated ligation
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
EP4242325A3 (de) 2020-04-22 2023-10-04 10X Genomics, Inc. Verfahren zur räumlichen analyse unter verwendung von gezieltem rna-abbau
EP4153775A1 (de) 2020-05-22 2023-03-29 10X Genomics, Inc. Simultane räumlich-zeitliche messung der genexpression und der zellaktivität
EP4153776A1 (de) 2020-05-22 2023-03-29 10X Genomics, Inc. Räumliche analyse zur erkennung von sequenzvarianten
WO2021242834A1 (en) 2020-05-26 2021-12-02 10X Genomics, Inc. Method for resetting an array
WO2021252499A1 (en) 2020-06-08 2021-12-16 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
EP4165207A1 (de) 2020-06-10 2023-04-19 10X Genomics, Inc. Verfahren zur bestimmung einer position eines analyten in einer biologischen probe
AU2021294334A1 (en) 2020-06-25 2023-02-02 10X Genomics, Inc. Spatial analysis of DNA methylation
US11981960B1 (en) 2020-07-06 2024-05-14 10X Genomics, Inc. Spatial analysis utilizing degradable hydrogels
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11981958B1 (en) 2020-08-20 2024-05-14 10X Genomics, Inc. Methods for spatial analysis using DNA capture
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
AU2021409136A1 (en) 2020-12-21 2023-06-29 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
WO2023034489A1 (en) 2021-09-01 2023-03-09 10X Genomics, Inc. Methods, compositions, and kits for blocking a capture probe on a spatial array

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US5104792A (en) * 1989-12-21 1992-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method for amplifying unknown nucleic acid sequences
US5994069A (en) * 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
US5846717A (en) * 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5503980A (en) * 1992-11-06 1996-04-02 Trustees Of Boston University Positional sequencing by hybridization
US5422252A (en) * 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5876924A (en) * 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
WO1996015271A1 (en) * 1994-11-16 1996-05-23 Abbott Laboratories Multiplex ligations-dependent amplification
US5985557A (en) * 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
EP1736554B1 (de) * 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Bestimmung von Unterschieden in der Nukleinsäuresequenz mittels einer Kombination von Ligasebestimmung und Polymerasekettenreaktion
WO1998015644A2 (en) * 1996-09-27 1998-04-16 The Chinese University Of Hong Kong Parallel polynucleotide sequencing method
WO1998035058A2 (en) * 1997-02-07 1998-08-13 Ribozyme Pharmaceuticals, Inc. Improved process for detection and quantification of nucleic acid molecules

Also Published As

Publication number Publication date
ATE409236T1 (de) 2008-10-15
AU6345700A (en) 2001-02-05
WO2001006012A1 (en) 2001-01-25
EP1194592A4 (de) 2004-12-08
EP1194592B1 (de) 2008-09-24
CA2379132C (en) 2011-05-31
EP1194592A1 (de) 2002-04-10
CA2379132A1 (en) 2001-01-25

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