DK0663445T3 - Fremgangsmåde til fremstilling af 7beta-(4-carboxybutanamido)-cephalosporansyre-acylase("GA")enzym - Google Patents

Fremgangsmåde til fremstilling af 7beta-(4-carboxybutanamido)-cephalosporansyre-acylase("GA")enzym

Info

Publication number
DK0663445T3
DK0663445T3 DK95200057T DK95200057T DK0663445T3 DK 0663445 T3 DK0663445 T3 DK 0663445T3 DK 95200057 T DK95200057 T DK 95200057T DK 95200057 T DK95200057 T DK 95200057T DK 0663445 T3 DK0663445 T3 DK 0663445T3
Authority
DK
Denmark
Prior art keywords
enzyme
carboxybutanamido
acylase
cephalosporanic acid
preparation
Prior art date
Application number
DK95200057T
Other languages
English (en)
Inventor
Der Goes Wilhelmus Van
Antonella Bernardi
Aldo Bosetti
Giuliana Franzosi
Pietro Cesti
Original Assignee
Mini Ricerca Scient Tecnolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog
Application granted granted Critical
Publication of DK0663445T3 publication Critical patent/DK0663445T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DK95200057T 1994-01-14 1995-01-11 Fremgangsmåde til fremstilling af 7beta-(4-carboxybutanamido)-cephalosporansyre-acylase("GA")enzym DK0663445T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI940031A IT1269180B (it) 1994-01-14 1994-01-14 Processo per la produzione dell'enzima acido 7beta- (4-carbossibutanamido)-cefalosporanico acilasi

Publications (1)

Publication Number Publication Date
DK0663445T3 true DK0663445T3 (da) 1999-11-01

Family

ID=11367491

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95200057T DK0663445T3 (da) 1994-01-14 1995-01-11 Fremgangsmåde til fremstilling af 7beta-(4-carboxybutanamido)-cephalosporansyre-acylase("GA")enzym

Country Status (8)

Country Link
US (2) US5612210A (da)
EP (1) EP0663445B1 (da)
JP (1) JP2805594B2 (da)
AT (1) ATE179755T1 (da)
DE (1) DE69509417T2 (da)
DK (1) DK0663445T3 (da)
ES (1) ES2132511T3 (da)
IT (1) IT1269180B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766871A (en) * 1996-11-27 1998-06-16 Food Industry Research And Development Institute Screening and characterization of glutaryl-7-aminocephalosporanic acid acylase
AU9742398A (en) * 1997-09-09 1999-03-29 Biochemie Gesellschaft Mbh Esterase free enzymes
FR3094492A1 (fr) * 2019-04-01 2020-10-02 Polyneuros Procédé de détection ou de suivi de l’évolution d’une maladie chronique dégénérative par dosage immunologique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2464298A1 (fr) * 1979-09-04 1981-03-06 Roquette Freres Procede de trempage du mais, produits ainsi obtenus et leur application a la fabrication de la penicilline
US4440792A (en) * 1982-09-07 1984-04-03 A. E. Staley Manufacturing Company Method for preventing gelation of corn steep liquor
ES2020792A6 (es) * 1990-08-03 1991-09-16 Antibioticos Sa Un procedimiento enzimatico para la presentacion de acido 7-amino-cefa-losporanico y un procedimiento para expresar la enzima 7b (4-carboxibutanamido) cefalosporinacilasa.
DE4136389A1 (de) * 1991-03-18 1992-10-08 Hoechst Ag Verfahren zur herstellung von glutarylacylase in grossen mengen

Also Published As

Publication number Publication date
US5801048A (en) 1998-09-01
DE69509417D1 (de) 1999-06-10
US5612210A (en) 1997-03-18
IT1269180B (it) 1997-03-21
JP2805594B2 (ja) 1998-09-30
DE69509417T2 (de) 1999-12-16
JPH07303483A (ja) 1995-11-21
ITMI940031A1 (it) 1995-07-14
ATE179755T1 (de) 1999-05-15
ITMI940031A0 (it) 1994-01-14
EP0663445A1 (en) 1995-07-19
EP0663445B1 (en) 1999-05-06
ES2132511T3 (es) 1999-08-16

Similar Documents

Publication Publication Date Title
Yamada et al. Nitrile hydratase and its application to industrial production of acrylamide
EP0188316B1 (en) Process for the preparation of amides using microorganisms
EP0187048A3 (en) Process for the production of soy hydrolysate, enzymatically modified soy protein and the use thereof as an egg white substitute
DK0625571T3 (da) Mikroorganismer, deres anvendelse samt fremgangsmåde til fremstilling af L-alfa-aminosyrer
DE60141633D1 (de) Neuartige glukose-6-phosphat dehydrogenase
US5814497A (en) Enzymatic hydrolysis of racemic a-substituted 4-methylthiobutyronitriles using a nitrilase from alcaligenes faecalis, gordona terrae or rhodococcus sp
DK0663445T3 (da) Fremgangsmåde til fremstilling af 7beta-(4-carboxybutanamido)-cephalosporansyre-acylase("GA")enzym
DK461985D0 (da) Fremgangsmaade til enzymatisk hydrolyse af d-alfa-aminosyreamider
EP0686698A3 (de) Biotechnologisches Verfahren zur Herstellung von cyclischen S-alpha-Aminocarbonsäuren und R-alpha-Aminocarbonsäureamiden
ATE35826T1 (de) Verfahren zur herstellung von l-alphaaminos|uren.
BR0012572A (pt) Processo para produção de l-aminoácidos de seus derivados racêmicos de n-acetil-d, l por dissociação de racemato enzimática por meio de enzimas isoladas, recombinantes
WO2003000910A3 (en) Metabolic controlled fermentation process for pseudomonic acid production
EP0775748A2 (en) Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon
DK0567323T3 (da) Forbedret fremgangsmåde til fremstilling af cephalosporiner
EP0194818A3 (en) Production of interleukin-2
IL81555A0 (en) Enzymatic process for 3-substituted cephalosporins
ES2093596T1 (es) Colesterol oxidasa nueva.
KR880003009A (ko) 카르니틴의 제조방법
KR970021294A (ko) 유기산 생성이 억제된 대장균 변이주
JPH0574353B2 (da)
SU1356455A1 (ru) Способ получения основы питательной среды для приготовления стафилококкового энтеротоксина типа а
WO2002095045A3 (fr) Procede de preparation d'acides carboxyliques aliphatiques par hydrolyse enzymatique de composes nitriles aliphatiques
GB1514837A (en) Microorganic strains and process for producing t-amino acids
JPH0367580A (ja) ストレプトミセスｓｐ．Ｙ―１８３及びヒダントイナーゼの製造方法
JPH05219969A (ja) α−ヒドロキシイソ酪酸の生物学的製造法