DK0658101T3 - Aerosolformuleringer fri for overfladeaktivt middel og indeholdende beclomethasondipropionat - Google Patents

Aerosolformuleringer fri for overfladeaktivt middel og indeholdende beclomethasondipropionat

Info

Publication number
DK0658101T3
DK0658101T3 DK93917708T DK93917708T DK0658101T3 DK 0658101 T3 DK0658101 T3 DK 0658101T3 DK 93917708 T DK93917708 T DK 93917708T DK 93917708 T DK93917708 T DK 93917708T DK 0658101 T3 DK0658101 T3 DK 0658101T3
Authority
DK
Denmark
Prior art keywords
surfactant
aerosol formulations
beclomethasone dipropionate
containing beclomethasone
formulations free
Prior art date
Application number
DK93917708T
Other languages
English (en)
Inventor
Philip John Neale
Anthony James Taylor
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929216381A external-priority patent/GB9216381D0/en
Priority claimed from GB929216382A external-priority patent/GB9216382D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK0658101T3 publication Critical patent/DK0658101T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK93917708T 1992-07-31 1993-07-30 Aerosolformuleringer fri for overfladeaktivt middel og indeholdende beclomethasondipropionat DK0658101T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929216381A GB9216381D0 (en) 1992-07-31 1992-07-31 Medicaments
GB929216382A GB9216382D0 (en) 1992-07-31 1992-07-31 Medicaments
PCT/EP1993/002040 WO1994003153A1 (en) 1992-07-31 1993-07-30 Surfactant free aerosol formulations containing beclomethasone dipropionate

Publications (1)

Publication Number Publication Date
DK0658101T3 true DK0658101T3 (da) 1998-09-21

Family

ID=26301356

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93917708T DK0658101T3 (da) 1992-07-31 1993-07-30 Aerosolformuleringer fri for overfladeaktivt middel og indeholdende beclomethasondipropionat

Country Status (11)

Country Link
EP (2) EP0775484B1 (da)
JP (1) JPH07509475A (da)
CN (1) CN1052401C (da)
AT (2) ATE248582T1 (da)
AU (1) AU670616B2 (da)
DE (2) DE69333187T2 (da)
DK (1) DK0658101T3 (da)
ES (2) ES2206619T3 (da)
GR (1) GR3026185T3 (da)
MX (1) MX9304585A (da)
WO (1) WO1994003153A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
WO1994021386A2 (en) * 1993-03-25 1994-09-29 Research Corporation Technologies, Inc. Polymers useful in forming self-assembled bonded anisotropic ultrathin layers and their use
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
GB9425160D0 (en) 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
US5747001A (en) * 1995-02-24 1998-05-05 Nanosystems, L.L.C. Aerosols containing beclomethazone nanoparticle dispersions
TR199701170T1 (xx) * 1995-04-14 1998-02-21 Glaxo Wellcome Inc. Beklometazon dipropionat i�in �l��lm�� doz inhaleri.
CZ292578B6 (cs) * 1995-04-14 2003-10-15 Glaxo Wellcome Inc. Inhalátor, inhalační systém
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US6068832A (en) * 1996-08-29 2000-05-30 Schering Corporation Chlorofluorocarbon-free mometasone furoate aerosol formulations
US6054487A (en) * 1997-03-18 2000-04-25 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
EP0998300A1 (en) * 1997-03-18 2000-05-10 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
AU4417500A (en) 1999-04-14 2000-11-14 Glaxo Group Limited Pharmaceutical aerosol formulation
US6540982B1 (en) * 2000-01-25 2003-04-01 Aeropharm Technology Incorporated Medical aerosol formulation
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
AU6124601A (en) 2000-05-10 2001-11-20 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
NZ528640A (en) * 2001-03-30 2004-06-25 Jagotec Ag Medical aerosol formulations
US6455028B1 (en) 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
CN100369608C (zh) * 2006-03-15 2008-02-20 修涞贵 一种治疗过敏性鼻炎的混悬液型喷雾剂及制备方法
RU2482495C2 (ru) * 2006-10-12 2013-05-20 Конинклейке Филипс Электроникс Н.В. Быстрый биосенсор со слоем реагента
DK2120875T3 (da) 2007-02-11 2018-10-22 Map Pharmaceuticals Inc Fremgangsmåde til terapeutisk administration af dhe med henblik på at muliggøre hurtig lindring af migræne samtidig med minimering af bivirkningsprofilen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1429184A (en) 1972-04-20 1976-03-24 Allen & Hanburys Ltd Physically anti-inflammatory steroids for use in aerosols
IT1121513B (it) 1979-05-28 1986-04-02 Chiesi Farma Spa Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol
ATE3774T1 (de) * 1980-05-02 1983-06-15 Schering Corporation Beclomethason-ester-solvate, verfahren zu ihrer herstellung und herstellung einer formulierung.
FI63672C (fi) * 1980-05-19 1983-08-10 Orion Yhtymae Oy Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan
KR880001237B1 (ko) 1984-07-25 1988-07-12 호비온 인터 리미티드 베클로메타손 17,21-디프로피오네이트의 용매화합물의 제조방법
GB8432063D0 (en) 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
DE69109284T2 (de) 1990-03-23 1995-08-24 Minnesota Mining & Mfg Verwendung von fluorierten löslichen tensiden zur herstellung von aerosolarzneimitteln mit dosierter abgabe.
HUT63554A (en) * 1990-06-29 1993-09-28 Fisons Plc Aerosol preparations under pressure
DK0553298T3 (da) 1990-10-18 1995-04-18 Minnesota Mining & Mfg Aerosolformulering omfattende beclomethason-17,21-dipropionat
EP0656206B1 (en) * 1991-06-10 2001-08-08 Schering Corporation Non-chlorofluorocarbon aerosol formulations
NZ243062A (en) * 1991-06-10 1993-09-27 Schering Corp Aerosol containing medicament and 1,1,1,2-tetrafluoroethane

Also Published As

Publication number Publication date
WO1994003153A1 (en) 1994-02-17
ATE162709T1 (de) 1998-02-15
CN1052401C (zh) 2000-05-17
JPH07509475A (ja) 1995-10-19
DE69316760T2 (de) 1998-06-04
EP0775484A1 (en) 1997-05-28
ES2206619T3 (es) 2004-05-16
GR3026185T3 (en) 1998-05-29
AU670616B2 (en) 1996-07-25
ES2112988T3 (es) 1998-04-16
MX9304585A (es) 1994-03-31
AU4705093A (en) 1994-03-03
ATE248582T1 (de) 2003-09-15
DE69333187T2 (de) 2004-07-15
EP0775484B1 (en) 2003-09-03
DE69316760D1 (de) 1998-03-05
EP0658101A1 (en) 1995-06-21
EP0658101B1 (en) 1998-01-28
DE69333187D1 (de) 2003-10-09
CN1088436A (zh) 1994-06-29

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