DK0640608T3 - Mellemprodukter til syntese af cephalosporiner - Google Patents
Mellemprodukter til syntese af cephalosporinerInfo
- Publication number
- DK0640608T3 DK0640608T3 DK94111894T DK94111894T DK0640608T3 DK 0640608 T3 DK0640608 T3 DK 0640608T3 DK 94111894 T DK94111894 T DK 94111894T DK 94111894 T DK94111894 T DK 94111894T DK 0640608 T3 DK0640608 T3 DK 0640608T3
- Authority
- DK
- Denmark
- Prior art keywords
- cephalosporins
- intermediates
- synthesis
- salts
- haca
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0152093A AT400717B (de) | 1993-07-30 | 1993-07-30 | Neue guanidin- und amidinsalze von 7-amino-3- hydroxymethyl-3-cephem-4-carbonsäure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0640608T3 true DK0640608T3 (da) | 2002-03-18 |
Family
ID=3515408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94111894T DK0640608T3 (da) | 1993-07-30 | 1994-07-29 | Mellemprodukter til syntese af cephalosporiner |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5639877A (da) |
| EP (1) | EP0640608B1 (da) |
| JP (1) | JP2939129B2 (da) |
| KR (1) | KR100378508B1 (da) |
| AT (2) | AT400717B (da) |
| DE (1) | DE69429224T2 (da) |
| DK (1) | DK0640608T3 (da) |
| ES (1) | ES2169053T3 (da) |
| PT (1) | PT640608E (da) |
| SG (1) | SG64370A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19961926A1 (de) | 1999-12-22 | 2001-07-05 | Basf Coatings Ag | Thermisch mit aktinischer Strahlung härtbare Stoffgemische und ihre Verwendung |
| AT411996B (de) | 2000-09-11 | 2004-08-26 | Sandoz Ag | Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes |
| CN102617506B (zh) * | 2011-01-31 | 2015-04-01 | 石药集团中奇制药技术（石家庄）有限公司 | 一种头孢地尼及其中间体的制备方法 |
| CN102617601A (zh) * | 2011-01-31 | 2012-08-01 | 石药集团中奇制药技术（石家庄）有限公司 | 一种头孢地尼的制备方法 |
| CN102775425A (zh) * | 2011-05-12 | 2012-11-14 | 华东理工大学 | 一种头孢卡品二异丙胺盐的一锅煮制备方法 |
| CN104072518A (zh) * | 2014-06-18 | 2014-10-01 | 威海昊同医药科技有限公司 | 一种头孢卡品二异丙胺盐的制备方法 |
| CN109503630A (zh) * | 2018-12-14 | 2019-03-22 | 河北合佳医药科技集团股份有限公司 | 一种去乙酰头孢噻肟的制备方法 |
| CN109678887B (zh) * | 2018-12-26 | 2020-08-14 | 湖北凌晟药业有限公司 | 一种盐酸头孢卡品酯中间体bcn的制备方法 |
| CN113025679B (zh) * | 2021-03-17 | 2023-04-28 | 石药集团内蒙古中诺药业有限公司 | 一种叔丁氧羰基头孢卡品前体酸的酶法制备工艺 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4331664A (en) * | 1976-04-12 | 1982-05-25 | Fujisawa Pharmaceutical Co., Ltd. | Syn isomer of 7-[2-cyclo(lower) alkoxyimino-2-(2-amino-or substituted aminothiazol-4-yl)acetamido]-3-lower alkanoyloxymethyl or heterocyclicthiomethyl-3-cephem-4-carboxylic acid compounds |
| US4430498A (en) * | 1979-03-01 | 1984-02-07 | Ciba-Geigy Corporation | 8-Oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene compounds |
| DK165118C (da) * | 1980-11-22 | 1993-03-01 | Gema Sa | Fremgangsmaade til fremstilling af oploesninger af 7-aminocephalosporansyrer |
| ES8505362A1 (es) * | 1983-05-26 | 1985-06-01 | Gema Sa | "sales de acidos amino-beta-lactamicos, para su aplicacion a la obtencion de n-acil derivados de los mismos, y procedimiento para la obtencion de dichas sales" |
| US4560749A (en) * | 1983-11-18 | 1985-12-24 | Eli Lilly And Company | Cephem-3-imidates and 3-amidines |
| DE3481769D1 (de) * | 1984-01-23 | 1990-05-03 | Takeda Chemical Industries Ltd | Cephemderivate und ihre herstellung. |
| US4833134A (en) * | 1986-08-19 | 1989-05-23 | Takeda Chemical Industries, Ltd. | Cephem compounds |
| EP0304858A3 (en) * | 1987-08-25 | 1989-12-20 | Takeda Chemical Industries, Ltd. | Cephem compounds, their production and use |
| ES2007428A6 (es) * | 1987-10-21 | 1989-06-16 | Palomo Coll Alberto | Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicos. |
| JP3121903B2 (ja) * | 1992-02-07 | 2001-01-09 | 塩野義製薬株式会社 | デアセチルセファロスポラン酸のカルバモイル化方法 |
-
1993
- 1993-07-30 AT AT0152093A patent/AT400717B/de not_active IP Right Cessation
-
1994
- 1994-07-28 JP JP6176880A patent/JP2939129B2/ja not_active Expired - Lifetime
- 1994-07-28 US US08/281,881 patent/US5639877A/en not_active Expired - Lifetime
- 1994-07-28 KR KR1019940018401A patent/KR100378508B1/ko active IP Right Grant
- 1994-07-29 ES ES94111894T patent/ES2169053T3/es not_active Expired - Lifetime
- 1994-07-29 DE DE69429224T patent/DE69429224T2/de not_active Expired - Lifetime
- 1994-07-29 EP EP94111894A patent/EP0640608B1/en not_active Expired - Lifetime
- 1994-07-29 AT AT94111894T patent/ATE209652T1/de active
- 1994-07-29 DK DK94111894T patent/DK0640608T3/da active
- 1994-07-29 PT PT94111894T patent/PT640608E/pt unknown
- 1994-07-29 SG SG1996008976A patent/SG64370A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT400717B (de) | 1996-03-25 |
| SG64370A1 (en) | 1999-04-27 |
| PT640608E (pt) | 2002-04-29 |
| ATA152093A (de) | 1995-07-15 |
| ATE209652T1 (de) | 2001-12-15 |
| JPH0753563A (ja) | 1995-02-28 |
| EP0640608A1 (en) | 1995-03-01 |
| DE69429224D1 (de) | 2002-01-10 |
| EP0640608B1 (en) | 2001-11-28 |
| KR950003299A (ko) | 1995-02-16 |
| JP2939129B2 (ja) | 1999-08-25 |
| US5639877A (en) | 1997-06-17 |
| DE69429224T2 (de) | 2002-07-25 |
| ES2169053T3 (es) | 2002-07-01 |
| KR100378508B1 (ko) | 2005-09-02 |
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