DK0630402T3 - Ny ketoesterreduktase, fremstilling deraf og anvendelse deraf til enzymatiske redoxreaktioner - Google Patents

Ny ketoesterreduktase, fremstilling deraf og anvendelse deraf til enzymatiske redoxreaktioner

Info

Publication number
DK0630402T3
DK0630402T3 DK93903849.3T DK93903849T DK0630402T3 DK 0630402 T3 DK0630402 T3 DK 0630402T3 DK 93903849 T DK93903849 T DK 93903849T DK 0630402 T3 DK0630402 T3 DK 0630402T3
Authority
DK
Denmark
Prior art keywords
preparation
redox reactions
keto ester
ester reductase
enzymatic redox
Prior art date
Application number
DK93903849.3T
Other languages
English (en)
Inventor
Maria-Regina Kula
Joerg Peters
Original Assignee
Forschungszentrum Juelich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich Gmbh filed Critical Forschungszentrum Juelich Gmbh
Application granted granted Critical
Publication of DK0630402T3 publication Critical patent/DK0630402T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/921—Candida

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK93903849.3T 1992-03-13 1993-03-05 Ny ketoesterreduktase, fremstilling deraf og anvendelse deraf til enzymatiske redoxreaktioner DK0630402T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4207921 1992-03-13

Publications (1)

Publication Number Publication Date
DK0630402T3 true DK0630402T3 (da) 1997-12-22

Family

ID=6453910

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93903849.3T DK0630402T3 (da) 1992-03-13 1993-03-05 Ny ketoesterreduktase, fremstilling deraf og anvendelse deraf til enzymatiske redoxreaktioner

Country Status (7)

Country Link
US (1) US5523223A (da)
EP (1) EP0630402B1 (da)
JP (1) JP3672307B2 (da)
CA (1) CA2117482C (da)
DE (1) DE59306681D1 (da)
DK (1) DK0630402T3 (da)
WO (1) WO1993018138A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3574682B2 (ja) * 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
DE59914278D1 (de) * 1998-02-18 2007-05-10 Lonza Ag Verfahren zur herstellung von trifluor-3(r)-hydroxybuttersäurederivaten
IL132500A0 (en) 1998-10-29 2001-03-19 Pfizer Prod Inc Stereoselective microbial reduction of a racemic tetralone
US6451587B1 (en) 1999-09-29 2002-09-17 Pfizer Inc. Microbial asymmetric reduction of 2-chloro-1-[-6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yl]-ethanone
US6884607B2 (en) * 2000-12-07 2005-04-26 Sumitomo Chemical Company, Limited Process for producing optically active 4-halo-3-hydroxybutanoate
BR0208265A (pt) * 2001-03-22 2004-03-02 Bristol Myers Squibb Co Redução estereosseletiva de acetofenona substituìda
EP1537222B1 (en) * 2002-08-09 2011-03-09 Codexis, Inc. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
DE10327454A1 (de) 2003-06-18 2005-01-20 Juelich Enzyme Products Gmbh Oxidoreduktase aus Pichia capsulata
JP2007502111A (ja) * 2003-08-11 2007-02-08 コデクシス， インコーポレイテッド ４−置換３−ヒドロキシ酪酸誘導体およびビシナルなシアノ，ヒドロキシ置換カルボン酸エステルの生成のための酵素的プロセス
AT413541B (de) * 2004-05-10 2006-03-15 Iep Gmbh Verfahren zur herstellung von 2-butanol
AT501928B1 (de) * 2004-10-27 2010-09-15 Iep Gmbh Verfahren zur herstellung von chiralen alkoholen
AT502395B1 (de) * 2005-07-27 2007-03-15 Iep Gmbh Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen
AT502185B1 (de) * 2005-09-23 2007-02-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
AT503486B1 (de) * 2006-04-11 2008-05-15 Iep Gmbh Verfahren zur enantioselektiven reduktion von steroiden
US8828704B2 (en) * 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
CN101528917B (zh) 2006-10-02 2015-07-29 科德克希思公司 用于制备立体异构纯的他汀类及其合成中间体的组合物和方法
AT504542B1 (de) 2006-12-07 2008-09-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten
TWI601825B (zh) * 2007-09-27 2017-10-11 Ｉｅｐ有限公司 對映異構選擇性酶催化還原中間產物之方法
EP2226386A1 (de) 2009-03-05 2010-09-08 IEP GmbH Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen
CN102803233B (zh) * 2009-06-22 2017-03-01 爱思开生物制药株式会社 制备氨基甲酸(r)‑1‑芳基‑2‑四唑基‑乙酯的方法
US8404461B2 (en) 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
CN103097400B (zh) 2010-05-27 2015-12-16 细胞制药有限公司 新的7α-羟类固醇脱氢酶敲除突变体及其用途
DE102013104418B4 (de) 2013-04-30 2018-09-27 Cambrex Iep Gmbh Biokatalytisches Verfahren für die Herstellung von (R)-3-Chinuclidinol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56160991A (en) * 1980-05-15 1981-12-11 Atsuyuki Kato Stabilized dihydrofolate reductase
SU1044631A1 (ru) * 1981-11-19 1983-09-30 Институт биохимии им.А.Н.Баха Способ получени ферментов 1.4.1.3,1-глутамат: АД( @ )+ -оксиредуктазы и 1.4.1.4,1-глутамат: АД( @ )+ -оксиредуктазы(дезаминирующих)
JPS59135889A (ja) * 1983-01-24 1984-08-04 Agency Of Ind Science & Technol トリメトプリムに対する耐性が増強したプラスミド
US5169758A (en) * 1986-05-02 1992-12-08 Boehringer Mannheim Gmbh Stabilized, NAD(P)H-dependent, soluble nitrate reductase, a process for the preparation thereof and a reagent containing it
DE3903759A1 (de) * 1989-02-09 1990-08-16 Ruetgerswerke Ag Verfahren zur herstellung von 2-oxochinolin
JPH0648981B2 (ja) * 1991-11-26 1994-06-29 工業技術院長 新規なジヒドロ葉酸還元酵素及び改変ジヒドロ葉酸還元酵素遺伝子

Also Published As

Publication number Publication date
JP3672307B2 (ja) 2005-07-20
EP0630402B1 (de) 1997-06-04
EP0630402A1 (de) 1994-12-28
JPH07505770A (ja) 1995-06-29
DE59306681D1 (de) 1997-07-10
CA2117482A1 (en) 1993-09-16
CA2117482C (en) 2005-02-15
US5523223A (en) 1996-06-04
WO1993018138A1 (de) 1993-09-16

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