DK0606336T3 - Fremgangsmåde til fremstilling af antimikrobielle quinolonyllactamer - Google Patents

Fremgangsmåde til fremstilling af antimikrobielle quinolonyllactamer

Info

Publication number
DK0606336T3
DK0606336T3 DK92920743.9T DK92920743T DK0606336T3 DK 0606336 T3 DK0606336 T3 DK 0606336T3 DK 92920743 T DK92920743 T DK 92920743T DK 0606336 T3 DK0606336 T3 DK 0606336T3
Authority
DK
Denmark
Prior art keywords
quinolone
compound
lactam
moiety
steps
Prior art date
Application number
DK92920743.9T
Other languages
Danish (da)
English (en)
Inventor
Ronald Eugene White
Thomas Prosser Demuth Jr
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Application granted granted Critical
Publication of DK0606336T3 publication Critical patent/DK0606336T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK92920743.9T 1991-10-01 1992-09-28 Fremgangsmåde til fremstilling af antimikrobielle quinolonyllactamer DK0606336T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76961591A 1991-10-01 1991-10-01

Publications (1)

Publication Number Publication Date
DK0606336T3 true DK0606336T3 (da) 1997-04-14

Family

ID=25085987

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92920743.9T DK0606336T3 (da) 1991-10-01 1992-09-28 Fremgangsmåde til fremstilling af antimikrobielle quinolonyllactamer

Country Status (22)

Country Link
US (1) US5281703A (zh)
EP (1) EP0606336B1 (zh)
KR (1) KR100253825B1 (zh)
CN (1) CN1046523C (zh)
AT (1) ATE150463T1 (zh)
AU (1) AU667837B2 (zh)
BR (1) BR9206590A (zh)
CA (1) CA2120493A1 (zh)
CZ (1) CZ73194A3 (zh)
DE (1) DE69218445T2 (zh)
DK (1) DK0606336T3 (zh)
ES (1) ES2101119T3 (zh)
FI (1) FI941490A (zh)
GR (1) GR3023227T3 (zh)
HU (1) HUT67423A (zh)
MX (1) MX9205620A (zh)
NO (1) NO304599B1 (zh)
NZ (1) NZ244557A (zh)
PT (1) PT100920B (zh)
RU (1) RU2130938C1 (zh)
SK (1) SK37594A3 (zh)
WO (1) WO1993007154A1 (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
DE69431684T2 (de) * 1993-12-28 2003-03-20 Kao Corp Vernetzte Zellulosefasern, absorbierende Papiere und absorbierende Elemente, Deckschicht und absorbierende Gegenstände, wobei diese Fasern Verwendung finden
CA2196538C (en) * 1994-08-02 2000-04-25 Jared Lynn Randall Process for making antimicrobial compounds
MX9700872A (es) * 1994-08-02 1997-05-31 Procter & Gamble Procedimiento para producir antimicrobianos de quinolonil-lactama y compuestos intermediarios novedosos.
US5607928A (en) * 1994-08-05 1997-03-04 Zeneca Limited Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives
EP0695753A1 (en) * 1994-08-05 1996-02-07 Zeneca Limited Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
WO1999028308A1 (en) * 1997-11-29 1999-06-10 Truett William L Antibiotics and process for preparation
US6437119B1 (en) 1998-05-07 2002-08-20 William Lawrence Truett Compounds formed from two or three antibiotics and their processes of preparation
US6638908B1 (en) * 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
US6947844B2 (en) * 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
IN191798B (zh) 2000-11-03 2004-01-03 Ranbaxy Lab Ltd
EP1245566B1 (en) * 2001-03-30 2004-01-07 Dar Al Dawa Development, and Investment Co. Quinolin-4-one derivatives and their use as antibiotics
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
CN1780846A (zh) * 2003-03-05 2006-05-31 Rib－X医药品有限公司 双官能杂环化合物及其制备和使用方法
US20070149463A1 (en) * 2003-10-30 2007-06-28 Oyelere Adegboyega K Bifunctional macrolide heterocyclic compounds and methods of making and using the same
WO2005049632A1 (en) * 2003-11-18 2005-06-02 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT49889A (en) * 1988-03-31 1989-11-28 Hoffmann La Roche Process for producing acyl derivatives
EP0366193A3 (en) * 1988-10-24 1992-01-08 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial quinolonyl lactams
ES2129388T3 (es) * 1988-10-24 1999-06-16 Procter & Gamble Pharma Fluoroquinolonil-cefems antimicrobianos.
ES2148135T3 (es) * 1988-10-24 2000-10-16 Norwich Eaton Pharma Nuevos esteres antimicrobianos de quinolonil lactamas.
EP0366189A3 (en) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial lactam-quinolones
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
DE69132256T2 (de) * 1990-04-18 2001-01-25 Procter & Gamble Pharma Antimikrobielle chinolonyl-lactame

Also Published As

Publication number Publication date
HUT67423A (en) 1995-04-28
RU2130938C1 (ru) 1999-05-27
BR9206590A (pt) 1995-04-25
NZ244557A (en) 1996-02-27
AU2693892A (en) 1993-05-03
DE69218445T2 (de) 1997-08-07
ATE150463T1 (de) 1997-04-15
AU667837B2 (en) 1996-04-18
FI941490A0 (fi) 1994-03-30
FI941490A (fi) 1994-05-02
US5281703A (en) 1994-01-25
KR100253825B1 (ko) 2000-05-01
MX9205620A (es) 1993-12-01
EP0606336B1 (en) 1997-03-19
CN1046523C (zh) 1999-11-17
PT100920B (pt) 1999-07-30
SK37594A3 (en) 1995-02-08
GR3023227T3 (en) 1997-07-30
ES2101119T3 (es) 1997-07-01
DE69218445D1 (de) 1997-04-24
PT100920A (pt) 1993-10-29
HU9400940D0 (en) 1994-06-28
CZ73194A3 (en) 1994-11-16
NO941108L (no) 1994-05-31
WO1993007154A1 (en) 1993-04-15
CA2120493A1 (en) 1993-04-15
NO304599B1 (no) 1999-01-18
NO941108D0 (no) 1994-03-25
CN1075146A (zh) 1993-08-11
EP0606336A1 (en) 1994-07-20

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