SK37594A3 - Method of preparation of antimicrobial quinolonyl lactams - Google Patents
Method of preparation of antimicrobial quinolonyl lactams Download PDFInfo
- Publication number
- SK37594A3 SK37594A3 SK375-94A SK37594A SK37594A3 SK 37594 A3 SK37594 A3 SK 37594A3 SK 37594 A SK37594 A SK 37594A SK 37594 A3 SK37594 A3 SK 37594A3
- Authority
- SK
- Slovakia
- Prior art keywords
- oxo
- carboxylic acid
- hydrogen
- alkyl
- bond
- Prior art date
Links
- 0 C[C@]([C@]([C@@]1SC(COC(N(CC2)C(C)CN2c(c(OC)c(c2c3)N(C4CC4)C=C(*)C2=O)c3F)=O)=C(*)N11)C1=O)O Chemical compound C[C@]([C@]([C@@]1SC(COC(N(CC2)C(C)CN2c(c(OC)c(c2c3)N(C4CC4)C=C(*)C2=O)c3F)=O)=C(*)N11)C1=O)O 0.000 description 4
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76961591A | 1991-10-01 | 1991-10-01 | |
| PCT/US1992/008246 WO1993007154A1 (en) | 1991-10-01 | 1992-09-28 | Process for making antimicrobial quinolonyl lactams |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK37594A3 true SK37594A3 (en) | 1995-02-08 |
Family
ID=25085987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK375-94A SK37594A3 (en) | 1991-10-01 | 1992-09-28 | Method of preparation of antimicrobial quinolonyl lactams |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5281703A (zh) |
| EP (1) | EP0606336B1 (zh) |
| KR (1) | KR100253825B1 (zh) |
| CN (1) | CN1046523C (zh) |
| AT (1) | ATE150463T1 (zh) |
| AU (1) | AU667837B2 (zh) |
| BR (1) | BR9206590A (zh) |
| CA (1) | CA2120493A1 (zh) |
| CZ (1) | CZ73194A3 (zh) |
| DE (1) | DE69218445T2 (zh) |
| DK (1) | DK0606336T3 (zh) |
| ES (1) | ES2101119T3 (zh) |
| FI (1) | FI941490A (zh) |
| GR (1) | GR3023227T3 (zh) |
| HU (1) | HUT67423A (zh) |
| MX (1) | MX9205620A (zh) |
| NO (1) | NO304599B1 (zh) |
| NZ (1) | NZ244557A (zh) |
| PT (1) | PT100920B (zh) |
| RU (1) | RU2130938C1 (zh) |
| SK (1) | SK37594A3 (zh) |
| WO (1) | WO1993007154A1 (zh) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| EP0661030B1 (en) * | 1993-12-28 | 2000-07-12 | Kao Corporation | Sanitary napkin |
| WO1996004286A1 (en) * | 1994-08-02 | 1996-02-15 | The Procter & Gamble Company | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds |
| CA2196538C (en) * | 1994-08-02 | 2000-04-25 | Jared Lynn Randall | Process for making antimicrobial compounds |
| EP0695753A1 (en) * | 1994-08-05 | 1996-02-07 | Zeneca Limited | Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use |
| US5607928A (en) * | 1994-08-05 | 1997-03-04 | Zeneca Limited | Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives |
| US5693791A (en) * | 1995-04-11 | 1997-12-02 | Truett; William L. | Antibiotics and process for preparation |
| WO1999028308A1 (en) * | 1997-11-29 | 1999-06-10 | Truett William L | Antibiotics and process for preparation |
| US6437119B1 (en) | 1998-05-07 | 2002-08-20 | William Lawrence Truett | Compounds formed from two or three antibiotics and their processes of preparation |
| US6947844B2 (en) * | 2000-08-09 | 2005-09-20 | Yale University | Modulators of ribosomal function and identification thereof |
| US6638908B1 (en) * | 2000-08-09 | 2003-10-28 | Yale University | Crystals of the large ribosomal subunit |
| IN191798B (zh) | 2000-11-03 | 2004-01-03 | Ranbaxy Lab Ltd | |
| ATE257468T1 (de) | 2001-03-30 | 2004-01-15 | Dar Al Dawa Dev And Invest Co | Chinolin-4-on derivate und deren verwendung als antibiotika |
| IL151012A0 (en) | 2001-08-03 | 2003-02-12 | Ribosomes Structure And Protei | Ribosomes structure and protein synthesis inhibitors |
| US6952650B2 (en) | 2001-08-03 | 2005-10-04 | Yale University | Modulators of ribosomal function and identification thereof |
| AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| CN1780846A (zh) * | 2003-03-05 | 2006-05-31 | Rib－X医药品有限公司 | 双官能杂环化合物及其制备和使用方法 |
| JP2007509980A (ja) * | 2003-10-30 | 2007-04-19 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 二官能性マクロライド複素環式化合物およびそれらの化合物を調製および使用する方法 |
| EP1699808A1 (en) * | 2003-11-18 | 2006-09-13 | Rib-X Pharmaceuticals, Inc. | Bifunctional macrolide heterocyclic compounds and methods of making and using the same |
| JP5383037B2 (ja) | 2004-02-27 | 2014-01-08 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 大環状化合物およびそれらを製造し使用する方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT49889A (en) * | 1988-03-31 | 1989-11-28 | Hoffmann La Roche | Process for producing acyl derivatives |
| SG67307A1 (en) * | 1988-10-24 | 1999-09-21 | Procter & Gamble Pharma | Novel antimicrobial quinolonyl lactam esters |
| EP0366640B1 (en) * | 1988-10-24 | 1999-02-03 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial fluoroquinolonyl cephems |
| EP0366189A3 (en) * | 1988-10-24 | 1992-01-02 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial lactam-quinolones |
| EP0366193A3 (en) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial quinolonyl lactams |
| ZA912279B (en) * | 1990-04-09 | 1992-02-26 | Hoffmann La Roche | Carbapenem compounds |
| CA2078444A1 (en) * | 1990-04-18 | 1991-10-19 | Thomas P. Demuth, Jr. | Antimicrobial quinolonyl lactams |
-
1992
- 1992-09-28 EP EP92920743A patent/EP0606336B1/en not_active Expired - Lifetime
- 1992-09-28 DE DE69218445T patent/DE69218445T2/de not_active Expired - Fee Related
- 1992-09-28 CZ CS94731A patent/CZ73194A3/cs unknown
- 1992-09-28 WO PCT/US1992/008246 patent/WO1993007154A1/en not_active Application Discontinuation
- 1992-09-28 BR BR9206590A patent/BR9206590A/pt not_active Application Discontinuation
- 1992-09-28 ES ES92920743T patent/ES2101119T3/es not_active Expired - Lifetime
- 1992-09-28 AU AU26938/92A patent/AU667837B2/en not_active Ceased
- 1992-09-28 KR KR1019940701029A patent/KR100253825B1/ko not_active IP Right Cessation
- 1992-09-28 CA CA002120493A patent/CA2120493A1/en not_active Abandoned
- 1992-09-28 AT AT92920743T patent/ATE150463T1/de not_active IP Right Cessation
- 1992-09-28 SK SK375-94A patent/SK37594A3/sk unknown
- 1992-09-28 DK DK92920743.9T patent/DK0606336T3/da active
- 1992-09-28 HU HU9400940A patent/HUT67423A/hu unknown
- 1992-09-28 RU RU94018240A patent/RU2130938C1/ru active
- 1992-09-30 MX MX9205620A patent/MX9205620A/es not_active IP Right Cessation
- 1992-09-30 NZ NZ244557A patent/NZ244557A/en unknown
- 1992-09-30 CN CN92112821A patent/CN1046523C/zh not_active Expired - Fee Related
- 1992-10-01 PT PT100920A patent/PT100920B/pt not_active IP Right Cessation
-
1993
- 1993-05-07 US US08/059,529 patent/US5281703A/en not_active Expired - Fee Related
-
1994
- 1994-03-25 NO NO941108A patent/NO304599B1/no not_active IP Right Cessation
- 1994-03-30 FI FI941490A patent/FI941490A/fi unknown
-
1997
- 1997-04-22 GR GR970400889T patent/GR3023227T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI941490A (fi) | 1994-05-02 |
| CZ73194A3 (en) | 1994-11-16 |
| EP0606336B1 (en) | 1997-03-19 |
| DE69218445T2 (de) | 1997-08-07 |
| PT100920B (pt) | 1999-07-30 |
| AU667837B2 (en) | 1996-04-18 |
| ATE150463T1 (de) | 1997-04-15 |
| FI941490A0 (fi) | 1994-03-30 |
| MX9205620A (es) | 1993-12-01 |
| HUT67423A (en) | 1995-04-28 |
| DE69218445D1 (de) | 1997-04-24 |
| DK0606336T3 (da) | 1997-04-14 |
| AU2693892A (en) | 1993-05-03 |
| HU9400940D0 (en) | 1994-06-28 |
| WO1993007154A1 (en) | 1993-04-15 |
| CN1075146A (zh) | 1993-08-11 |
| NZ244557A (en) | 1996-02-27 |
| EP0606336A1 (en) | 1994-07-20 |
| NO304599B1 (no) | 1999-01-18 |
| KR100253825B1 (ko) | 2000-05-01 |
| ES2101119T3 (es) | 1997-07-01 |
| RU2130938C1 (ru) | 1999-05-27 |
| CA2120493A1 (en) | 1993-04-15 |
| US5281703A (en) | 1994-01-25 |
| NO941108D0 (no) | 1994-03-25 |
| GR3023227T3 (en) | 1997-07-30 |
| CN1046523C (zh) | 1999-11-17 |
| BR9206590A (pt) | 1995-04-25 |
| PT100920A (pt) | 1993-10-29 |
| NO941108L (no) | 1994-05-31 |
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