DK0568821T3 - Calluscelleinduktion og fremstilling af taxaner - Google Patents

Calluscelleinduktion og fremstilling af taxaner

Info

Publication number
DK0568821T3
DK0568821T3 DK93105668T DK93105668T DK0568821T3 DK 0568821 T3 DK0568821 T3 DK 0568821T3 DK 93105668 T DK93105668 T DK 93105668T DK 93105668 T DK93105668 T DK 93105668T DK 0568821 T3 DK0568821 T3 DK 0568821T3
Authority
DK
Denmark
Prior art keywords
taxanes
preparation
cell induction
callus cell
callus
Prior art date
Application number
DK93105668T
Other languages
Danish (da)
English (en)
Inventor
Paul M Cino
Steven R Schwarz
Dana L Cazzulino
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Application granted granted Critical
Publication of DK0568821T3 publication Critical patent/DK0568821T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
DK93105668T 1992-04-07 1993-04-06 Calluscelleinduktion og fremstilling af taxaner DK0568821T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86482692A 1992-04-07 1992-04-07

Publications (1)

Publication Number Publication Date
DK0568821T3 true DK0568821T3 (da) 2000-03-06

Family

ID=25344160

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93105668T DK0568821T3 (da) 1992-04-07 1993-04-06 Calluscelleinduktion og fremstilling af taxaner

Country Status (9)

Country Link
US (2) US5527702A (fr)
EP (1) EP0568821B1 (fr)
JP (1) JP3228592B2 (fr)
AT (1) ATE184646T1 (fr)
CA (2) CA2434692A1 (fr)
DE (1) DE69326377T2 (fr)
DK (1) DK0568821T3 (fr)
ES (1) ES2136099T3 (fr)
GR (1) GR3032105T3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
CA2434692A1 (fr) * 1992-04-07 1993-10-08 Paul M. Cino Induction de cellules de cal et la preparation de taxanes
AU3265195A (en) * 1994-08-26 1996-03-22 Institute Of Materia Medica Chinese Academy Of Medical Sciences Novel taxol derivative
US20050158699A1 (en) * 1995-06-07 2005-07-21 Kadkade Prakash G. Cryopreservation of plant cells
US5965438A (en) * 1995-06-07 1999-10-12 Phyton, Inc. Cryopreservation of plant cells
KR20090005241A (ko) 1996-05-24 2009-01-12 디에프비 바이오테크 인코포레이티드 탁수스종의 세포 배양에 의한 탁산의 생산 증진 방법
EP2266607A3 (fr) 1999-10-01 2011-04-20 Immunogen, Inc. Des immunoconjugués pour le traitement des cancers.
US6452024B1 (en) 2000-02-22 2002-09-17 Chaichem Pharmaceuticals International Process for extraction and purification of paclitaxel from natural sources
US6759539B1 (en) 2003-02-27 2004-07-06 Chaichem Pharmaceuticals International Process for isolation and purification of paclitaxel from natural sources
KR20070086651A (ko) 2003-05-23 2007-08-27 스태니슬로 카르핀스키 400 ｎｍ 내지 700ｎｍ의 파장의 광선을 주사하여 식물세포 내의 식물성 화학물질의 농도를 변경하는 방법 및기구
EP1739184A1 (fr) * 2005-06-28 2007-01-03 Centro Biotecnologie Avanzate Méthode pour la production du taxol et/ou des taxanes des cultures des cellules de noisette
CN100427588C (zh) * 2006-09-15 2008-10-22 清华大学 紫杉细胞的培养方法及其专用培养基
CN1932024B (zh) * 2006-09-15 2010-09-29 清华大学 紫杉醇的生物合成方法及其专用培养基
JP4563493B2 (ja) * 2009-02-25 2010-10-13 タヒボジャパン株式会社 ナフトキノン系抗がん活性成分の効率的製造

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2747334A (en) * 1952-05-20 1956-05-29 Pfizer & Co C Cultivation of plant tissue
GB1495709A (en) * 1974-01-28 1977-12-21 British Petroleum Co Method and apparatus for growing plant cells
US4038778A (en) * 1976-09-27 1977-08-02 Gte Laboratories Incorporated Tissue culture technique for asexual plant reproduction and a medium for use therewith
US4152214A (en) * 1977-10-07 1979-05-01 The United States Of America As Represented By The Secretary Of Agriculture Production of homodeoxyharringtonine and other cephalotaxine esters by tissue culture
US4206221A (en) 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
US4463522A (en) * 1979-07-26 1984-08-07 Eckhart Lindemann System and apparatus for plant tissue culture propagation
US4501815A (en) * 1979-10-29 1985-02-26 Albert Einstein College Of Medicine Of Yeshiva University Article for culturing differentiated cells
US4352887A (en) * 1979-10-29 1982-10-05 Albert Einstein College Of Medicine Of Yeshiva University Method and article for culturing differentiated cells
ATE8797T1 (de) * 1980-11-06 1984-08-15 Albright & Wilson Limited Schwielenkultur in einer nahrhaften stroemung.
IL69333A (en) * 1983-07-26 1986-04-29 Biolog Ind Process for plant tissue culture propagation
CH665217A5 (de) * 1985-02-15 1988-04-29 Agrogen Stiftung Verfahren und vorrichtung zur in vitro kultur von pflanzenzellen, pflanzengeweben, pflanzenorganen, pflanzenteilen sowie zur mikropropagation und regeneration von ganzen pflanzen.
JPS61254127A (ja) * 1985-05-02 1986-11-11 三浦　喜温 ニチニチソウ器官培養によるインド−ルアルカロイドの製造方法
US4960703A (en) * 1986-04-23 1990-10-02 Personnalite Juridique De La Station Des Cultures Fruitieres Et Maraicheres Composition for in vitro micropropagation of plants
CA1289902C (fr) * 1987-05-15 1991-10-01 Jean Archambault Immobilisation de cellules vegetales sur une surface
US5019504A (en) 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
WO1992013961A1 (fr) * 1991-02-12 1992-08-20 Nippon Steel Corporation PROCEDE POUR PRODUIRE DU TAXOL PAR CULTURE CELLULAIRE DE L'ESPECE $i(TAXUS)
US5413928A (en) * 1991-06-21 1995-05-09 Worcester Polytechnic Institute Process for extracting enhanced amounts of plant secondary metabolites with limited loss of plant viability
WO1993002067A1 (fr) * 1991-07-17 1993-02-04 Nippon Steel Corporation Compose antitumoral nsc-lsc1 et son procede de production
US5344775A (en) * 1991-11-15 1994-09-06 Escagenetics Corporation Synthesis of taxanes in culture using pseudocalluscells
IT1258838B (it) * 1992-01-31 1996-02-29 Indena Spa Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species
JPH05244971A (ja) * 1992-03-06 1993-09-24 Nippon Oil Co Ltd タキサン類化合物の製造方法
EP0633719A4 (fr) * 1992-04-01 1995-12-20 Union Camp Corp PROCEDE POUR INDUIRE UNE EMBRYOGENESE SOMATIQUE DANS LE -i(TAXUS) ET PRODUCTION D'ALCALOIDES CONTENANT UN NOYAU DE TAXANE SELON CE PROCEDE.
CA2434692A1 (fr) * 1992-04-07 1993-10-08 Paul M. Cino Induction de cellules de cal et la preparation de taxanes
US5322779A (en) * 1992-04-16 1994-06-21 The Research And Development Institute, Inc. At Montana State University Taxol production by taxomyces andreanae
AU4242993A (en) * 1992-05-21 1993-12-13 Penn State Research Foundation, The Cultured (taxus) tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds
CA2069122A1 (fr) * 1992-05-21 1993-11-22 Richard N. Arteca Methodes and compositions pour la production of taxol, de precurseurs du taxol et de derives du taxol provenant de cultures de tissus vegetaux
JP2967532B2 (ja) * 1992-06-11 1999-10-25 日石三菱株式会社 タキサン類化合物の製造方法

Also Published As

Publication number Publication date
EP0568821A1 (fr) 1993-11-10
US5527702A (en) 1996-06-18
CA2434692A1 (fr) 1993-10-08
DE69326377D1 (de) 1999-10-21
DE69326377T2 (de) 2000-05-11
JPH0678758A (ja) 1994-03-22
US5665576A (en) 1997-09-09
ES2136099T3 (es) 1999-11-16
JP3228592B2 (ja) 2001-11-12
EP0568821B1 (fr) 1999-09-15
CA2092849C (fr) 2003-11-18
ATE184646T1 (de) 1999-10-15
GR3032105T3 (en) 2000-03-31
CA2092849A1 (fr) 1993-10-08

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