DK0563278T3 - Regulering af geneekspression med ioniserende stråling - Google Patents

Regulering af geneekspression med ioniserende stråling

Info

Publication number
DK0563278T3
DK0563278T3 DK92903431T DK92903431T DK0563278T3 DK 0563278 T3 DK0563278 T3 DK 0563278T3 DK 92903431 T DK92903431 T DK 92903431T DK 92903431 T DK92903431 T DK 92903431T DK 0563278 T3 DK0563278 T3 DK 0563278T3
Authority
DK
Denmark
Prior art keywords
tissues
ionizing radiation
gene expression
regulation
enhancer
Prior art date
Application number
DK92903431T
Other languages
English (en)
Inventor
Ralph R Weichselbaum
Vikas P Sukhatme
Donald W Kufe
Dennis E Hallahan
Original Assignee
Dana Farber Cancer Inst Inc
Arch Dev Corp The University O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc, Arch Dev Corp The University O filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of DK0563278T3 publication Critical patent/DK0563278T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0023—Agression treatment or altering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
DK92903431T 1990-12-20 1991-12-19 Regulering af geneekspression med ioniserende stråling DK0563278T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63362690A 1990-12-20 1990-12-20
PCT/US1991/009651 WO1992011033A1 (en) 1990-12-20 1991-12-19 Control of gene expression by ionizing radiation

Publications (1)

Publication Number Publication Date
DK0563278T3 true DK0563278T3 (da) 2000-08-21

Family

ID=24540424

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92903431T DK0563278T3 (da) 1990-12-20 1991-12-19 Regulering af geneekspression med ioniserende stråling

Country Status (10)

Country Link
US (2) US5612318A (da)
EP (1) EP0563278B1 (da)
JP (1) JP3337214B2 (da)
AT (1) ATE190354T1 (da)
AU (1) AU657111B2 (da)
CA (1) CA2098849C (da)
DE (1) DE69132031T2 (da)
DK (1) DK0563278T3 (da)
ES (1) ES2144414T3 (da)
WO (1) WO1992011033A1 (da)

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Also Published As

Publication number Publication date
DE69132031T2 (de) 2000-07-13
EP0563278A4 (da) 1994-02-02
EP0563278B1 (en) 2000-03-08
ES2144414T3 (es) 2000-06-16
AU9170291A (en) 1992-07-22
US5817636A (en) 1998-10-06
US5612318A (en) 1997-03-18
WO1992011033A1 (en) 1992-07-09
JPH06506194A (ja) 1994-07-14
DE69132031D1 (de) 2000-04-13
EP0563278A1 (en) 1993-10-06
JP3337214B2 (ja) 2002-10-21
AU657111B2 (en) 1995-03-02
CA2098849A1 (en) 1992-06-21
ATE190354T1 (de) 2000-03-15
CA2098849C (en) 2007-07-10

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